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RESOURCE GUIDE FOR DEVELOPING

BELOW THE LINE MATERIALS – CONSUMERS

Disclaimer
This material (Resource for Developing BTL Material for Consumers) has been created only as a guide for constru cting a
detailing aid for consumers and it is not intended to be distributed to any external recipient in this format. Most of th e
information con tained in this template detailing aid is related to fiber in gen eral and it may not n ecessarily be correct
for every type of fiber. Before being used, as a whole or parts of it, the template detailing aid must be adapted to
reflect th e local environment and it must be locally reviewed and approved by Medical, Regulatory and Legal.
YOUR DIGESTIVE SYSTEM

The digestive system is a group of organs responsible for the “digestion” process:

• Ingestion: involves the entry


of food and fluids into the
body through the mouth
• Digestion: begins in the
mouth, immediately after
ingestion to break down
complex mole cules into
simpler ones. Digestion
involves both chemical
processes (caused by
digestive enzymes such as
amylase and pepsin) and
mechanical processes (i.e.
mastication in the mouth
and churning in the
stomach).

• Absorption: necessary to provide energy and certain essential compounds,


such as vitamins and minerals, to cells and organs.
• Defecation: elimination of unabsorbed and undigested food residues plus
the waste products of metabolism.

The digestive tract is separated into an upper part and a lower part and is
comprised of the follo wing organs:

2
DIGESTIVE DISORDERS –
UNCOMFORTABLE AND DISTRESSING
Digestive disorders are very common and can affect millions of people
throughout the world. Many people suffer from digestive proble ms, with symptoms
that range from changes in bowel habits (constipation/infrequent stools) to
abdominal problems (discomfort, cramping, bloating, ‘gurgling’ in the bowel, and
flatulence).

These symptoms can cause discomfort, inconvenience and distress and are
often debilitating enough to cause suffering and stop you from fully enjoying your
daily life.

Causes
Often, the symptoms signify no more than a temporary change in bowel habit,
usually caused by multiple factors such as stress, fatigue, a diet high in fat and
low in fiber, smoking or excessive alcohol consumption. If digestive proble ms
have been experie nced for at least 3 days per month in the last 3 months, it is
most likely that they are caused by irritable bowel syndrome (IBS). This is a
common conditio n that affects around 10–15% of the general population1.
However, more serio us conditions such as inflammatory bowel disease or
diverticular disease may be causing the problems; therefore, if symptoms persist
you should consult your doctor.

Irritable bowel syndrome

3
COULD FIBER BE THE ANSWER TO YOUR DIGESTIVE
PROBLEMS?

It has been recognized for many years that diets high in dietary fiber lead to a low
prevalence of obesity, cardiovascular diseases and bowel irregularitie s or more
serious conditions. In contrast, the low-fiber, highly-refined diet of the develo ped
world is associated with a much higher prevalence of all of these conditions.

Recommended daily intakes of fiber vary from 20–40 g/day, depending on age
and gender. However, due to modern busy lifestyle and eating habits, it is often
very difficult to achie ve these recommended levels with regular die t and many
people would require a fiber supplement, which can be bought over-the-counter.

Recommended daily intake (RDI) of fiber


US American Dietetic 20–35 g/day for healthy adults plus 5 g/day
Association for children
>25 g/day, preferably from whole grain
World Health Organization
foods
Minimum fiber intake 12–24 g/day for healthy
British Nutrition Foundation
adults
Adults less than 50 years, 38 g/day for men,
Food and Nutrition Board of the 25 g/day for women
Institute of Medicine Adults older than 50 years, 30 g/day for men,
21 g/day for women

Types of fiber
Fiber is either classed as dietary or functional:

• Dietary fibers are the edible parts of plants that are not broken down in the
digestive system and therefore arrive in the large intestine intact.
• Functional fibers are isolated, extracted or synthetic non-digestible fibers that
may be added to the diet.

All fibers can also be sub-classified as soluble (dissolve in water) or non-soluble


(pass through the intestines almost intact), as well as fermentable (broken down by
the natural bacteria in the large intestine to form essential fatty acids) or non-
fermentable (excreted virtually intact).

4
IN GENERAL, DIETARY FIBER CAN OFFER YOU SUBSTANTIAL
HEALTH BENEFITS

Fiber (whether obtained from the diet or added to your healthy, regular diet in the
form of a supplement) has several beneficial effects in the body and has a
positive impact on the regularity of the digestive system:

• Alleviates constipation and helps to restore healthy bowel habits by retaining


water in the bowel and increasing the water content of stools2–14.

• Reduces loose stools and diarrhea by decreasing contractio ns of the


intestinal muscles, increasing bowel transit time and stimulating sodium and
water absorptio n in the colon13,15–18.

• Act as an energy source for many body cells by increasing the formation of
‘short-chain fatty acids’ (SCFA)19,20.

• Has a beneficial ‘prebiotic’ effect by promoting the formation of the natural


‘good’ (probiotic ) bacteria in the large intestine and inhibiting the growth of
potentially harmful bacteria21–28.

• Gives a feeling of ‘fullness’ after eating, but has low nutrient value so won’t
cause weight gain. In fact, high fiber intake is associated with lower body
weight and body fat and so increased fiber intake may lead to weight
reduction21,29–39.

• Can help to reduce sugar levels in the blood, especially after eating40–59.

• May reduce ‘bad’ LDL-cholesterol in the blood, with potential positive


effects on the cardio vascular system19,60–62.

• Can increase absorption of certain minerals and nutrients (e.g. calcium,


magnesium, zinc) by the intestines63–67.

• Has a positive effect on the immune system by improving the ability of the
intestine wall to resist entry of harmful bacteria and by stimulating the growth
of “good” bacteria and the productio n of immune cells and antibodies68,69.

5
BENEFIBER IS AN EXCELLENT SOLUTION TO HELP YOU GET
THE DAILY FIBER YOU NEED
What is Benefiber?
y Benefiber is a revolutionary food supplement containing the soluble,
fermentable fiber of natural origin, wheat dextrin.

y The wheat dextrin in Benefiber is processed using heat and enzymes so that it
arrives in the large intestine virtually intact and provides all the benefits of
dietary fiber.

y Benefiber is non-thickening so is easy to take and


blends easily with food without altering their taste
or texture.

y Benefiber is:

– Sugar free
– Gluten free
– Sodium free (<5mg /100g)
– Clear
– Taste-free
– Dissolves completely

y Benefiber provides the benefits of dietary fiber in a


convenient and easy-to-use supplement, and can help you maintain a good
digestive health.

Nutritional information for wheat dextrin

Per 1 serving = 3.9 g


Per 100 g
(= 2 teaspoons)
Energy 200 kcal (835 kJ) 7 kcal (29 kJ)
Protein <0.5 g < 0.018 g
Carbohydrates (sugars,
15 g 0.525 g
polyalcohol, starch)
Fat — —
Dietary fiber 85 g 3g
Potassium <1 mg <0.035 mg
Sodium <5 mg <0.175 mg
* Dry solids basis

6
BENEFIBER CAN HELP PROVIDE THE BENEFITS
OF DIETARY FIBER

Wheat dextrin of Benefiber promotes digestive health through its dual action:

7
Wheat dextrin contained in Benefiber produces significant amounts of SCFAs,
including butyrate, which nourish the digestive system and provide energy to
organs, like the colon19

Wheat dextrin produces significantly more SCFA over 24 ho urs than inulin and
psyllium19

Wheat dextrin promotes the production of 40% greater amounts of butyrate


than PHGG 19

Wheat dextrin promotes 39% greater SCFA production than PHGG 19

8
Wheat dextrin provides a slower, more steady rate of SCFA production than
inulin (enhancing effectiveness and improving tolerability 19

Wheat dextrin is fermented slowly and gradually, leading to a significantly high


production of SCFA, while helping to minimize the undesirable effects of gas
production and flatulence. Because of its slow fermentatio n, Benefiber is easy for
your digestive system to tolerate, as demonstrated in clinical studies where
subjects consumed up to 45 g of wheat dextrin (equal to 15 servings.21,70.

9
The wheat dextrin in Benefiber acts as a prebio tic, stimulating the growth of
’good’ intestinal bacteria21,22

Consumption of wheat dextrin increases the concentration of beneficial


lactobacillus bacteria21

Consumption of wheat dextrin decreases the concentration of harmful


intestinal bacteria (clostridia) 21

Wheat dextrin helps balance intestinal microflora21

10
Wheat dextrin, the fiber in Benefiber, enhances the absorption and retention of
important minerals such as magnesium and calcium71

Improved nutrition/mineral absorption with wheat dextrin71

Significance
Diet Dextrose diet Benefiber
(p value)
Calcium
Apparent absorption,
187 (28.8) 269 (37.4) 0.093
mean mg/day (%)
Retention, mean
39.3 111 0.122
mg/day
Magnesium
Apparent absorption,
65 (30.4) 117 (50.9) 0.001
mean mg/day (%)
Retention, mean
–0.3 30.9 0.024
mg/day

11
BENEFIBER MAKES MAINTAINING DIGESTIVE HEALTH
EASIER72

• 9 out of 10 people who trie d Benefiber felt it improved their health

• After 3-weeks of use, two-thirds of consumers felt that Benefiber improved their
digestive health

• Fiber users rate Benefiber as effective as inulin, but significantly more effective
than psyllium

• Benefiber users reported significantly fewer side effects than inulin users

• People who used Benefiber (wheat dextrin) reported significantly lower side
effects than those who used inulin

Tolerability was better for Benefiber than for inulin as demonstrated by the side
effects attributed to use of wheat dextrin among fiber supplement users* 72
Benefiber wheat
Inulin Psyllium
dextrin
Total consumers 174 181 153
(n)
Yes (%) 14 25A 18
B
No (%) 86 75 82
* Question asked, “Did you experience any abdominal pain, discomfort, bloating, gas,
diarrhea and/or constipation while using this product over the past few days/weeks that you
attribute to its use?”
Statistical significance at the 90% confidence level compared with A wheat dextrin, B
inulin

12
• Benefiber users reported higher compliance than psyllium users after a 3-
weeks of use

Compliance was better for Benefiber than for psyllium as demonstrated by the
length of wheat dextrin use among fiber supplement users* 72
Benefiber wheat
Inulin Psyllium
dextrin
Total consumers (n) 174 181 153
Response (%)
More than 14 days 31C 23 19
14 days 15C 16C 7
13 days 4 3 1
12 days 3 7 8A
11 days 0 3 2
10 days 12 10 11
9 days 2 4 4
8 days 3 4 3
7 days 12 11 11
6 days 3 7 7
5 days 5 4 8
4 days 3 4 6
3 days 4 3 3
2 days 1 0 6A,B
1 days 0 0 3A,B
Mean 11.0C 10.7C 8.9
* Question asked, “How many days did you use this product?”
Statistical significance at the 90% confidence level compared with A wheat dextrin, B in ulin , C
psyllium

72
Frequency of wheat dextrin use per day among fiber supplement users*

Benefiber wheat
Inulin Psyllium
dextrin
Total consumers (n) 174 181 153
Response (%)
More than 3
2 4C 0
times/day
3 times/day 10 7 9
2 times/day 45B,C 32 27
1 time/day 43 56A 64A
Mean 1.7C 1.6 1.5
* Question asked, “How many times per day, on average, did you use this product?”
Statistical significance at the 90% confidence level compared with A wheat dextrin, B In ulin , C
psyllium

13
HOW SHOULD BENEFIBER BE USED?

Because it is clear, taste-free and dissolves completely, Benefiber does not alter
the taste or texture of soft foods or beverages.

It is recommended that 2 teaspoons (3.9 g) Benefiber powder (equivalent to 3 g


fiber) are dissolved in 120–240 ml of any non-carbonated beverage or mixed with
and equivalent amount of soft hot or cold food.

All natural Benefiber makes taking fiber easier

• 100% fiber ingredient of natural origin

• Dissolves completely in beverages and soft food

• Non-gelling and never thickens

• Sugar, sodium and gluten free

• Wheat dextrin, the fiber contained in Benefiber, is


well tolerated, even at high doses21,70

• Benefiber helps provide many benefits associated


with dietary fiber:

– It has a prebiotic effect, helping to promote


healthy intestinal flora to normalize bowel
function and maintain digestive balance

– It can help provide the physiologic al and health benefits associated with
SCFA production in the bowel

– It is fermented gradually and slowly helping to minimize the undesirable


problem of intestinal gas productio n

– It may help improve the absorption and retentio n of calcium and


magnesium

– It has low glycemic and insulinemic indices

14
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