Introduction to

biostatistics: COVID-19
2021
Professor: Fernando Vidal-Ostos
Email: fvidal-osto@alumni.unav.es

Prof. Dr. Paul Nguewa

Emails: panguewa@unav.es
 Index
• What is Covid-19?
• Key concepst.
• Transmition.
• What is basic reproduction number or Ro?.
• Take home message.
 Contex of Covid-19?
• The COVID-19 of the acronym "coronavirus disease 2019", is the
protagonist of the global pandemic that we are currently
experiencing.
• With great health, economic and social repercussions. To date
more than 84 million confirmed cases and more than 1.8 million
deaths worldwide.
 What is Covid-19?
• SARS-CoV-2 is an RNA virus with a single
positive sense strand, enveloped in a lipid
membrane. It belongs to the genus
Betacoronavirus.
• Its genome consists of approximately 30
kilobases (kb) and encodes four structural
protein.
• Although the most important is the S protein
(Spike protein) that envelops the coronavirus
giving rise to a morphology similar to a
"crown", which is why it receives the name of
coronavirus.
 Transmission of Covid-19?
• Transmission of SARS-CoV-2 occurs between infected humans and
susceptible persons.
 Key concepts of Covid-19
• COVID-19 is produced by the SARS-CoV-2 infection and is responsible
for the worldwide pandemic we are now living through.
• SARS-Cov-2 is an RNA virus.
• The SARS-Cov-2 genome consists of 30 Kb.
• And It encodes 4 structural proteins, the most important of which is S.
• Transmission:
• Direct contact.
• Contaminated objects.
• Airborne transmission.
Basic reproduction Number (Ro)
• Ro is the average number of new cases, which will produce a new case in an
infectious period.
• It is an estimator of the capacity of an infectious disease to be transmitted in a
population.
• It is a very useful parameter in the
field of public health and indicates
when it would be necessary to
establish prevention measures (R0
>1).
• According to WHO data, the R0 of
SARS-CoV-2 is estimated to be
between 1.5 and 2.5.
Basic reproduction Number (Ro)
https://www.youtube.com/watch?v=om5aLPdwTyc
Thank you!
Merci!
Gracias!
Prof. Fernando Vidal-Ostos
Email: fvidal-osto@alumni.unav.es
Prof. Dr. Paul Nguewa
Emails: panguewa@unav.es
References:
• https://www.elsevier.com/books/bioestadistica-amigable/martinez-
gonzalez/978-84-9113-407-7
• https://www.researchgate.net/publication/274068806_Nociones_bas
icas_de_Estadistica
• https://www.slideshare.net/rdhaker2011/introduction-to-
statisticsppt-rahul
• https://apps.who.int/iris/handle/10665/44055 (Eléments
d'épidémiologie, 2éme éd)
• https://www.geeksforgeeks.org/difference-between-descriptive-and-
inferential-statistics/