NCOMP ATIBIL1T1 ES IN RESCRIPTJON

Dr. Parjanya Shukla

&
Inom pahbibhis OCCUs as a osult o Dr. M. P. Singh Clasms

mixing too oo mov antogonisfie Aubstans

On undlesirabl brodut s fomud

which oct K Aofaty , eficaty and oppaoranu

"phammacuuital praparaHon
ThintracHon o har drug wih otken dg
Comus undun incompaibiihs du oh additiu
addliues wlh addiHves
LdOaqe mor

Lncompakbihis ma occua Duwng Compounding and disparsing

duun man actuing
Packaging 0
ad miniatrahion

y s ntompaibljhis-
By-Dr. Mahandra frakap SIngh
(A) Physital TntompahbiibHas
(B) Chamica IntompahibiuHs
CC) TRenabLuhic IntombahHbiliH

Phyaical lncombahibibHs
Da. When tuo OT mo Aubatoncas au ombinad
toqehn
immisubibty, insalubilty
AhyAical chonq Haupitaton
liquthracton
 Phyaical Tntombaibilit vi» ib and Jasiby
(017actad by abplytng Dr. Parjanya Shukla

Dr. M. P. Singh lasses

hamaauhetd akil

*Phyaikal i'ntombahbidiy Con bi touchad by

i) Chonq OTden mixing
Emuliicaton
ii) AddiHono Auwpending agent
(iv) Change in om i'nqmdent
(v) addiHon, Aubsti uron oT omion d
enabuhcally inachiu Aubalan

By-Dr. Mahundra fraub Singk

Exombla
Tmmisubibty-
Castor oil IS ml
Watsr upto 60 ml

Emulsu/y ing agent Is sd.

R ephacinu Suly hata 0-25

Men hol 0 02 m

Laguid onoffin uto 30 m

Ephadrin Slþhats not holubb in liguid porohin

Aubahbuted i t onhydros ephudvin (Salubls in Liqusd pororin)
2
()Praiplobion Dr. Parjanya Shuhla
&
TnchTA benzoin (ompalund 5.0 ml Dr. M. P. Singh Classes

Clycan IS-0 ml
Kos woaY upto 00 md

Tnctu hunzoin contu'n OsinA

ehong in Aalunt Ault raupitakon

addihion oa Hinchuy wih xabid himing

yiald innt talladal dispuvaion.

(4) osfrachon
Manhol 5
5
Comphor
Ammonium chlmid 30
ught maq nesium Carbonate 60

Menhol t Comphort Ammnum chlemol

ge igupad on mixing

add light magneAium carbonah »

}rlooing9
owdowder.
By-Dr.M.P.Singk
ChemicalTncompahbibi
Ww

x Chimical incompaibility iult du to

Chamica intavachion b/w inqradients

om toxicoY inachut broduc

3
Lohil disbenxing Buh prnphion Dr. Parjanya Shukla

Ritk brewnt for mation d Kormu produe r. M.P. Singh Cto

Y
COTYRc am and inom t pcnkr.

Chumical Intompatibilhs au
hoo tyhe
Toaraled Adjastad
minimised by chonginq thi ordey prontad by odbion o7
mixing 0Y mixin 80luhiom Anhshtuhon ons of Ka
in dlHl fom uacHng inrudant wik
(No albnab'on mads in Povmulo) anothun qual tnabukc
valu
Cy-Dr.Makandrofrakab Sins
Chemica IntompoHkies moy be

tenhona Unintenhional

Jhen prasnber prsnb Jhen prscnhad torhau

knowingly pYCnhaud knowing k Incompaibilit.
intompafthl duqs
exampls -

(alfains cirat 4.0

oclium dalicylake 30
watr upto

Crtr'c aud d Cetwin tihaB1 xuack toih Sodium Aaluelate to

yiald aubitabid ailicylic aud
 Thavopulic Thtombalibiiky Dr. Parjanya Shukla

x Thrapuhc incombatibilihy may ull Dr. M.P. Stingh Classes

rAs Cribinq dug for spauise degrae o

phaacolog/eal acHon
but

natur 0Y hanaity of th achion dijusn from

mkandud bka xnbr.
xThis ocur du to-

(4) EmoY In do0

2 Wrong dug OT dozaqe oTm
(3) Conra - indicatud drug.
(4)SyneTgishc oY antagonishic druqa.
5) ntarachons
(1) Eror in doxag By-Dr. Mahu ndra Praab Singk

Ahro pin Aulphaa 0006 &

Phuno barbitone 001S
Aapirin 6-300

quanthty aropinu Aulbhats moy han maimum do

So lumad back to TAACnbr Por COTTLCHon
(3) Wrong d or dosage Pom
Grtain druq hau qwte imilor namu -

ik
»padnisonand prAdnisoJonalwayp
diqoxin and diqitoxin danqar o
wTonq dYu
 (3) Conha-indicaked dugs
'

:
Dr. Parjanya Shukla

Slbhodiozin
Sulpha maragini
950 m
So m
Dr. M. P. Singh Clase

Hmmmium chlondu 5o0 m

Ammonium chlondu umnamy auidiT

Caus depaniion d Alpho namids ehyshl in kid nay

oDYLSYphon Julaxad back to pnb

4) ynu1qihic and antagonishic drug4-

Aaty Aalicylic auid 0-69

obenecid
boh au ud to trea qaut but Combina-on laad to
nauragaHon d achon
5) Drug intarachona' By-Dr.Mahundra hroap Sing

Auwophenhidin ISO
Aahy) salitylie arid 00 m
analauucA
ollein 30 m

Autophonetidin depr th CNS (undesirabla)

Cofln sHmulah CNS

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