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29/12/2021, 10:44 HELLP Syndrome: The State of the Art : Obstetrical & Gynecological Survey

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December 2004 - Volume 59 - Issue 12
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CME Program: CATEGORY 1 CME REVIEW ARTICLES 34 35 AND 36: CME REVIEW ARTICLE 36

HELLP Syndrome: The State of the Art


Baxter, Jason K. MD*; Weinstein, Louis MD†

Author Information
*Clinical Instructor, Department of Obstetrics and Gynecology, Fellow, Division of Maternal–Fetal Medicine, †Paul
A. and Eloise B. Bowers Professor and Chairman of Obstetrics and Gynecology, Thomas Jefferson University,
Philadelphia, Pennsylvania

CHIEF EDITOR’S NOTE: This article is part of a series of continuing education activities in this Journal through
which a total of 36 AMA/PRA category 1 credit hours can be earned in 2004. Instructions for how CME credits can
be earned appear on the last page of the Table of Contents.

Address correspondence to: Jason K. Baxter, MD, Suite 400, 834 Chestnut Street, Philadelphia, PA 19107. E-mail:
Jason.Baxter@jefferson.edu.

The authors have disclosed no significant financial or other relationship with any commercial entity.
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29/12/2021, 10:44 HELLP Syndrome: The State of the Art : Obstetrical & Gynecological Survey

Obstetrical & Gynecological Survey:


December 2004 - Volume 59 - Issue 12 - p 838-845
doi: 10.1097/01.ogx.0000146948.19308.c5
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Abstract
Preeclampsia/eclampsia has been recognized for centuries and continues to plague both the patient and the
obstetrician. A severe variant, the syndrome of hemolysis, elevated liver enzymes, and low platelets (HELLP), has
been recognized for 50 years. Although much new data has been elucidated about the condition, only several
observations have withstood the test of time. These are the uniqueness of the disease to humans, the progressive
nature of the disease, and the fact that delivery is the sole therapy.

Target Audience: 
Obstetricians & Gynecologists, Family Physicians

Learning Objectives: 
After completion of this article, the reader should be able to outline the history of HELLP syndrome and describe
the pathophysiology of HELLP syndrome, to summarize the clinical presentation and differential diagnosis of
HELLP syndrome, and to list the various management options.

© 2004 Lippincott Williams & Wilkins, Inc.


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