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Bovine Spongiform Encephalopathy-Scrapie Antigen Test Kit (BSE-Scrapie)
Bovine Spongiform Encephalopathy-Scrapie Antigen Test Kit (BSE-Scrapie)
Bovine Spongiform Encephalopathy-Scrapie Antigen Test Kit (BSE-Scrapie)
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 1 of 15
BSE 99-09437
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 8/20/2012
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 8/20/2012
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 8/20/2012
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 8/20/2012
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 8/20/2012
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0
Company IDEXX Laboratories, Inc. IDEXX Laboratories Pty Ltd. IDEXX Europe B.V.
One IDEXX Drive Metro Centre Scorpius 60 Building F
Westbrook, ME 04092 Unit 20, 38-46 South Street Hoofddorp 2132 LR
United States Rydalmere, NSW 2116 Australia The Netherlands
Telephone 1-800-548-6733 1-800-655-978 00800 727 43399
Fax 1-207-556-4346 1-800-634-409 00800 433 99329
Conditioning buffer
Acute Toxicity, Oral, Category 4
Chronic Aquatic Toxicity, Category 3
Pictogram
Negative control
Skin Irritation, Category 2
Serious Eye Damage, Category 1
Pictogram
Conditioning buffer
Hazard symbol(s) Xn Harmful
N Dangerous for the environment
R-phrase(s) R22 Harmful if swallowed.
R32 Contact with acids liberates very toxic gas.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in
the aquatic environment.
S-phrase(s) S45 In case of accident or if you feel unwell, seek medical advice
immediately.
S61 Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
Negative control
Hazard symbol(s) Xi Irritant
R-phrase(s) R38 Irritating to skin.
R41 Risk of serious damage to eyes.
S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S28 After contact with skin, wash immediately with plenty of soap and water.
S37/39 Wear suitable gloves and eye/face protection.
Conditioning buffer
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Alkaliine salts and alkaline earth salts - - 615-030-00-5 - < 50%
of thiocyanic acid
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Conjugate diluent
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 2%
ProClin 150 - - - - ≤ 0.5%
Negative control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trometamol 77-86-1 201-064-4 - TY2900000 < 10%
N-lauroylsarcosine 97-78-9 202-608-3 - - ≤ 5%
Triton X-100 9036-19-5 - - MD0907600 ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Plate diluent 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 5%
Zwittergent 3-14 14933-09-6 239-003-9 - - ≤ 5%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Plate diluent 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trypsin 9002-07-7 232-650-8 647-010-00-7 YN5075000 < 7%
Trometamol 77-86-1 201-064-4 - TY2900000 < 4%
Positive control
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Trade secret - - - - < 30%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.2%
Substrate solution
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Substrate solution - - - - 100%
Wash solution 1
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
N-lauroyl sarcosine 97-78-9 202-200-5 - - ≤ 1%
Sodium azide 26628-22-8 247-852-1 011-004-00-7 VY8050000 ≤ 0.1%
Wash solution 2
Substance CAS-No. EC-No. Index-No. RTECS-No. Concentration
Sodium chloride 7647-14-7 231-598-3 - VZ4725000 < 10%
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 6 of 15
BSE 99-09437
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Conditioning buffer
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth. Call a POISON CENTER or doctor/physician if you feel unwell.
Negative control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth.
Plate diluent 2
IF INHALED: Remove victim to fresh air and keep comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER/doctor.
IF ON SKIN: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
IF SWALLOWED: Rinse mouth.
Positive control
IF INHALED: Remove victim to fresh air and keep comfortable for breathing.
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. Rinse skin with water/shower. Wash
contaminated clothing before reuse.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTER or
doctor/physician.
5. FIRE FIGHTING MEASURES
Environmental precautions
Avoid release to the environment. Collect spillage.
Positive control
Soak up with inert absorbent material and dispose of as hazardous waste.
7. HANDLING AND STORAGE
Exposure Controls
Handle in accordance with good industrial hygiene and safety practice. Do not get in eyes, on skin, or on clothing.
Control parameters
Substance Country Value Control parameter Update
Trade Secret Australia TWA 1 mg/m3 07.2008
STEL 2 mg/m3
Belgium TWA 1 mg/m3 03.2002
STEL 2 mg/m3
Denmark TWA 0.5 mg/m3 10.2002
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 8 of 15
BSE 99-09437
N-lauroylsarcosine
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 10 of 15
BSE 99-09437
ProClin 150
Acute toxicity LD50 Oral - rat - 2630 mg/kg
Skin corrosion/irritation Skin - rabbit - Corrosive
Serious eye damage/eye irritation Eyes - rabbit - Corrosive to eyes
Respiratory or skin sensitization guinea pig - May cause sensitization by skin contact.
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium azide
Acute toxicity LD50 Oral - rat - 27 mg/kg
LC50 Inhalation - rat - 37 mg/m3
LD50 Dermal - rabbit - 20 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Sodium chloride
Trade secret
Acute toxicity LD50 Oral - rat - 350 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Triton X-100
Acute toxicity LD50 Oral - rat – 1,800 mg/kg
LD50 Dermal - rabbit – 8,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation Eyes - rabbit - Risk of serious damage to eyes.
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – no data available
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trometamol
Acute toxicity LD50 Oral - rat – 5,900 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Trypsin
Acute toxicity LD50 Oral - rat - > 5,000 mg/kg
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization May cause allergic respiratory and skin reactions
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
Zwittergent 3-14
Acute toxicity no data available
Skin corrosion/irritation no data available
Serious eye damage/eye irritation no data available
Respiratory or skin sensitization no data available
Germ cell mutagenicity no data available
Carcinogenicity IARC: No component of this product present at levels greater than or equal to
0.1% is identified as probable, possible or confirmed human carcinogen by
IARC.
Reproductive toxicity no data available
Specific Target Organ Toxicity – Inhalation - May cause respiratory irritation.
Single Exposure
Specific Target Organ Toxicity – no data available
Repeated Exposure
Aspiration hazard no data available
12. ECOLOGICAL INFORMATION
N-lauroylsarcosine
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
ProClin 150
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium azide
Toxicity to fish LC50 - Lepomis macrochirus – 0.68 mg/l - 96 h
Toxicity to daphnia and other aquatic EC50 - Daphnia pulex (Water flea) – 4.2 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Sodium chloride
Toxicity to fish no data available
Toxicity to daphnia and other aquatic NOEC - Daphnia - 1500 mg/l - 7 d
invertebrates. LC50 - Daphnia magna (Water flea) - 1661 mg/l - 48 h
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trade secret
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 14 of 15
BSE 99-09437
Toxicity to fish LC50 - Cyprinus carpio (Carp) - 0.4 - 2.2 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia magna (Water flea) - 0.2 mg/l - 48 h
invertebrates
Toxicity to algae Growth inhibition LOEC - Pseudokirchneriella subcapitata - 12.5 mg/l - 96 h
Persistence and degradability no data available
Bioaccumulative potential Bioaccumulation Pimephales promelas (fathead minnow) - 63d
Bioconcentration factor (BCF): 21.000
Mobility in soil no data available
PBT and vPvB assessment no data available
Triton X-100
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - 8.9 mg/l - 96.0 h
Toxicity to daphnia and other aquatic EC50 - Daphnia - 26 mg/l - 48 h
invertebrates
Toxicity to algae no data available
Persistence and degradability Biotic/Aerobic Biochemical oxygen demand - Exposure time 28 d
Result: 36 % - Not readily biodegradable.
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Other adverse effects Chemical Oxygen Demand (COD) – 2.19 mg/g
Trometamol
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Trypsin
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
PBT and vPvB assessment no data available
Zwittergent 3-14
Toxicity to fish no data available
Toxicity to daphnia and other aquatic no data available
invertebrates.
Toxicity to algae no data available
Persistence and degradability no data available
Bioaccumulative potential no data available
Mobility in soil no data available
Print Date: 4/20/2018
Document #: msds-102 -EN
Version: B
MATERIAL SAFETY DATA SHEET Revision Date: 08/09/2012
CO #: 061685
BSE-Scrapie 99-08600 Page: 15 of 15
BSE 99-09437
Packaging group
USDOT: III ADR/RID: III IMDG: III IATA: III
Environmental hazards
USDOT: yes ADR/RID: yes IMDG Marine pollutant: yes IATA: yes
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
HMIS Ratings
Conjugate concentrate, Conjugate diluent, Reconstitution buffer, SRB conjugate concentrate, Wash solution 2
Conditioning buffer, Negative control, Plate diluent 1, Plate diluent 2, Wash solution 1
Health hazard 1 Flammability 0 Physical hazard 0
Positive Control
Health hazard 2 Flammability 0 Physical hazard 0