USAGE OF

STEM
CELLS
 Reasons to Store Baby’s Stem Cells

1 in every 200 people will need to undergo a stem cell

transplantation in their life time.

1 of the top 10 common cancers in India, Non-Hodgkins's

lymphoma, is a stem cell treatable disease.

2 of the top 5 most common childhood cancers in India,

Leukemia and Lymphoma, are treatable with stem cells.

1 in 500 babies in the world has cerebral palsy, a neurological

disorder incurred at birth, which may be treated with cellular
therapy.

Umbilical Cord V/s Bone Marrow

Umbilical Cord Bone Marrow
Easy to collect Invasive process

Painless Extreme painful

No surgical intervention Surgical intervention

Potentiality of stem cells are high Stem cells with more maturity

Lesser chance of GVHD Higher risk of GVHD

HLA – More acceptable HLA – Difficult to match

Rich source, contains 10 times more Lesser quantity of stem cells derived
Stem cells derived human pelvic bone
Stem cells derived from biological waste part
through series of injections

No Risk Chances of side effects

Potential Uses of Stem Cells
 Standard Therapies

Acute Lymphoblastic
Refractory Anemia Aplastic Anemia
Leukemia (ALL)

Refractory Anemia with

Acute Myelogenous
Ringed Sideroblasts Fanconi Anemia
Leukemia (AML)
(Sideroblastic anemia)

Congenital
Acute Biphenotypic Refractory Anemia
Dyserythropoietic
Leukemia with Excess Blasts
Anemia

Chronic Lymphocytic Refractory Anemia Paroxysmal Nocturnal

Leukemia (CLL) with Excess Blasts Hemoglobinuria (PNH)
in Transformation

Chronic
Chronic Myelogenous
Myelomonocytic Sickle Cell Disease
Leukemia (CML)
Leukemia (CMML)

Juvenile Chronic Beta Thalassemia

Myelogenous Hodgkin's Lymphoma Major
Leukemia (JCML) (aka Cooley's Anemia)

Juvenile Non-Hodgkin's
Myelomonocytic Lymphoma Diamond-Blackfan
Leukemia (JMML) (Burkitt's Lymphoma) Anemia
 Standard Therapies

Agnogenic Myeloid
Pure Red Cell Aplasia Omenn Syndrome Metaplasia
(Myelofibrosis)

Amegakaryocytosis / Infantile Genetic

Congenital Agranulocytosis Digeorge Syndrome
Thrombocytopenia (Kostmann Syndrome)

Glanzmann Hemophagocytic
Myelokathexis
Thrombasthenia Lymphohistiocytosis

SCID with Adenosine

Leukocyte Adhesion
Deaminase Deficiency Ataxia-Telangiectasia
Deficiency
(ADA-SCID)

Bare Lymphocyte Lymphoproliferative

SCID which is X-linked
Syndrome Disorders

SCID with absence of Common Variable Wiskott-Aldrich

T & B Cells Immunodeficiency Syndrome

SCID with absence of

Digeorge Syndrome Acute Myelofibrosis
T Cells, Normal B Cells
 Standard Therapies

Polycythemia Vera Plasma Cell Leukemia Systemic Mastocytosis

Essential Waldenstrom’s Morquio Syndrome

Thrombocythemia Macroglobulinemia (MPS-IV)

Chediak-Higashi Cartilage-Hair Maroteaux-Lamy

Syndrome Hypoplasia Syndrome (MPS-VI)

Sly Syndrome (MPS-VII)

Chronic Granulomatous Erythropoietic Porphyria (beta-glucuronidase
Disease deficiency)

Neutrophil Actin Hermansky-Pudlak Mucolipidosis II

Deficiency Syndrome (I-cell Disease)

Adrenoleukodystrophy
Reticular Dysgenesis Pearson's Syndrome
(ALD)

Krabbe Disease
Shwachman-Diamond
Multiple Myeloma (Globoid Cell
Syndrome
Leukodystrophy)
 Standard Therapies

Metachromatic
Neuroblastoma Niemann-Pick Disease
Leukodystrophy

Pelizaeus-Merzbacher
Medulloblastoma Sandhoff Disease
Disease

Wolman Disease Retinoblastoma Lesch-Nyhan Syndrome

Osteopetrosis

Therapies in Clinical Trial

Hypoxic Ischemic
Cerebral Palsy Traumatic Brain Injury
Encephalopathy (HIE)

Spinal Cord Injury Autism Hearing Loss

Amyotrophic Lateral
Crohn's Disease Diabetes, Type 1
Sclerosis (ALS)

Graft-versus-Host Kidney plus stem cell

Disease (GvHD) transplant
 Therapies in Clinical Trial

Lupus Compartment Syndrome Fanconi Anemia

Multiple Sclerosis Ischemic Stroke HIV

Metachromatic
Rheumatoid Arthritis Ischemic Heart Disease Leukodystrophy

Support for Misc. Severe Combined

Myocardial Infarction
Open Cardiac Surgery Immunodeficiency

Hypoplastic Left Heart

Cardiomyopathy Sickle Cell
Syndrome (HLHS)

Critical Limb Ischemia Adrenoleukodystrophy Thalassemia

Chronic Granulomatous Wiskott-Aldrich

Grow vascular graft
Disease (X-linked) Syndrome
 Therapies in Clinical Trial

Alveolar Cleft Bronchopulmonary

Knee Cartilage Repair
Palate Repair Dysplasia (BPD)

Epidermolysis Bullosa Lysosomal Storage

HIV aka "AIDS"
Diseases

Clinical Trial with stemcells from Cord Tissue

Alzheimer's Disease Autism Lupus

Diabetes, Type 1 Spinal Cord Injury Liver Cirrhosis

Ataxia (Hereditary) Rheumatoid Arthritis Cerebral Palsy

Hypoxic Ischemic
Aplastic Anemia Cardiomyopathy
Encephalopathy (HIE)

Graft-versus-Host
Multiple Sclerosis Traumatic Brain Injury
Disease (GvHD)
Media Articles
Media Articles
Success of Cryoviva
 Cerebral Palsy

Cerebral palsy the most common

childhood physical disability strikes
approximately 2.5 of every 1000 live
term berths and increases to 22 of every
1000 live premature births. Diagnosis of
Cerebral Palsy (CP) refers to problems
with neural control of motor function,
which leads to complication in behavior,
learning, communication epilepsy,
vision, hearing, perception and
sensation.*

Stem cells transplants of Cryoviva clients

DATE OF AUTOLOGOUS/ DOCTOR
RECEPIENT AGE/ SEX HOSPITAL DIAGNOSIS
ISSUE ALLOGENIC IN-CHARGE
Aurov NCRM, Dr. Deepak
Kartaveeryarjuna 5/16/2009 06 months/ M Autologous Cerebral Palsy
Chennai Ranade
Teja

Sir Gangaram Dr. Anupam

Praneit Singh 1/11/2011 2½ Years/ M Autologous Cerebral Palsy
Delhi Sachdeva

Autologous Holy Angel

Vihaan Dutta 5/6/2014 04 Years/M Dr. B.S. Rajput Cerebral Palsy
Delhi

Aarav Mishra 4/4/2016 5½ Years/ M Sibling Holy Angel Dr. B.S. Rajput Cerebral Palsy
Delhi

* MacLennan A. A template for defining a causal relation between acute intrapartum events and
cerebral palsy: international consensus statement. BMJ 1999; 319: 1054-1059
 Thalassemia Major

Thalassemia syndromes are a heterogeneous group of single

gene disorders, inherited in an autosomal recessive manner,
prevalent in certain parts of the world. Worldwide, 15 million
people have clinically apparent thalassemic disorders. Every
year approximately 100,000 children with Thalassemia Major
are born world over, of which 10,000 are born in India.*

Stem cells transplants of Cryoviva clients

DATE OF AUTOLOGOUS/ DOCTOR
RECEPIENT AGE/ SEX HOSPITAL DIAGNOSIS
ISSUE ALLOGENIC IN-CHARGE
Harshita BLK Memorial Dr. Dharma Thalassemia
2/26/2010 07 Years/ F Sibling
Agarwal Delhi Chaudhary Major

Apollo Thalassemia
Auronisha Roy 6/9/2010 05 Years/ F Sibling Dr. Revathi Raj
Chennai Major
Bhavna BLK Memorial Dr. Dharma Thalassemia
11/24/2010 14½ Years/ F Sibling
Manglani Delhi Chaudhary Major

Apollo Thalassemia
Preeti Jain 11/14/2011 05 Years/ M Sibling Dr. Revathi Raj
Chennai Major

BLK Memorial Dr. Dharma Thalassemia

Vanshika 12/19/2011 10 Years/ F Sibling
Delhi Chaudhary Major

Krishana Sir Gangaram Dr. Sathya Thalassemia

4/20/2012 07 Years/ F Sibling
Ladhani Delhi Prakash Yadav Major

Apollo Thalassemia
Vibish 6/17/2013 04 Years/ M Sibling Dr. Revathi Raj
Chennai Major

Apollo Thalassemia
Maryam 7/29/2013 07 Years/ F Sibling Dr. Revathi Raj
Chennai Major

Dr. M. Joseph Thalassemia

Lakshya 8/14/2014 11 Years/ M Sibling CMC, Ludhiana
John Major
Rajiv Gandhi Dr. Rayaz Thalassemia
Navya 4/14/2015 06 Years/ F Sibling Cancer Institute
Ahmed Major
Delhi
Shubham Soni Manipal Dr. Satyendra Thalassemia
11/3/2015 10 Years/ M Sibling
Agarwal Jaipur Katewa Major

* Weatherall DJ, Clegg JB. The Thalassemia Syndromes. 4th ed. Oxford:
Blackwell Scientific Publications; 2001
 Brain Tumor

The cause of most primary brain tumours is unknown, research

into this is ongoing. Brain tumours, like other tumours, are not
infectious and can't be passed on to other people. They are
slightly more common in men than in women. In the year 2006
at TATA Memorial Hospital in Mumbai, India 372 people were
diagnosed with Brain and Central Nervous System Tumours, out
of which 250 (67%) were males and 122 (33%) were females.*

Stem cells transplants of Cryoviva clients

DATE OF AUTOLOGOUS/ DOCTOR
RECEPIENT AGE/ SEX HOSPITAL DIAGNOSIS
ISSUE ALLOGENIC IN-CHARGE

Natsha Shah 1/19/2015 06 Years/ F Autologous Denvax Clinic Dr. Jamal

Brain Tumor
Delhi A Khan

* http://www.healthlibrary.com/book77_chapter947.htm
Let’s serve your patients with once in a lifetime
opportunity of stem cells banking
 Words from a baby yet to be born

Hello Doctor………
Thanks for taking care of me and my mom during pregnancy. My
stem cells are the precious gift of god, which can ensure the
health for lifelong.
I would request you to kindly get it preserved.
 Cryoviva Biotech Pvt. Ltd.
(Formerly known as Cryobanks International India Pvt. Ltd.)

129, Pace City-1, Sector 37, Gurgaon, Haryana-122001, (India)

Tel. No.: 0124-4734100 – 110, Fax No.: 0124-4734111
Toll Free: 1-800-102-2796 (Airtel), Helpline No.: +91 9582 28 4444
Website: www.cryoviva.in, Email: support@cryoviva.in
CIN No.: U85195DL2005PTC137768, Regd. Office: F-2/7, Okhla Industrial Area, Phase I, New Delhi-110020

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