Immunoglobuli Structure Function Location Unique Thing

n
G Single Y-shaped unit (monomer) Levels Found in Only maternal
increase in all body antibody that
chronic fluids crosses
infections. placenta to
provide passive
crosses natural
placenta to immunity
provide
passive Most abundant
natural in serum
immunity.

Useful in Main antibody in

Rh secondary
incompatibilit response
y

Triggers
foreign cell
destruction
mediated
by
complemen
t system.
A single (monomer) or double unit (dimer) 1. Inhibits Found on The most
held together by J chain adherence of mucosal predominant
microbes. surfaces antibody in the
and in colostrum
2. Promotes secretion
phagocytosis s e.g., Second most
and intracellular saliva, abundant in
killing of tears, serum.
microbes. sweat,
milk,
3. Provides colostrum
defence against
salmonella,
vibrio cholera,
polio
and influenza.
Protection
against
“CORONA “

4. Protects
newborn during
first month of
life.
M Composed of 5 Y-shaped units (IgG Protection Blood largest
type) held together by a J polypeptide against stream immunoglobulin
chain. Thus, IgM is a pentamer. toxoplasmosis,
rubella, HIV, NOT
CMV TRANSPORTE
D ACROSS
500-1000 times PLACENTA.
more effective
than IgG in IgM can
opsonization simultaneously
and 20 times combine with
more effective in 5 antigenic sites
bacterial due to its
agglutination. pentameric
structure.
Absence results
in septicemia. Produced in
 primary
response to
antigen
E IgE is a single Y-shaped monomer The IgE Mainly in IgE levels
molecules ECF are elevated in
tightly bind with individuals with
mast cells which Present in allergies
release small
histamine and amounts
cause allergy in lining of
respiratory
IgE is and
associated with intestinal
Hypersensitivity tracts.
Type 1
reactions
involved in
asthma, hay
fever, eczema,
parasitic
infections

D Resembles IgG in structure. Helps in IgD Their function,

inducing B cell molecules however, is not
response are known for
present on certain. Some
the workers believe
surface of that
B cells IgD may
function as B-
Present in cell receptor.
the ECF