Introduction

Ophthalmic drugs are agents especially designed to be applied to the eyes. The eye is
extremely sensitive and is easily irritated if the composition of the ophthalmic preparation is
not appropriate. Ophthalmic preparations deliver a drug on the eye, into the eye, or onto the
conjunctiva. Drugs are administered to the eye for local effects such as miosis, mydriasis, and
anesthesia, or to reduce intraocular pressure in treating glaucoma.

Types of Ophthalmic drugs

1 Anti-angiogenic ophthalmic agents?

Anti-angiogenic ophthalmic agents act as vascular endothelial growth factor (VEGF) antagonists.
When retinal pigment cells become ischemic and dry up VEGF stimulates generation of new blood
vessels by a process called neovascularization. During the generation of new blood vessels in the
retina, if the blood vessels do not generate properly it causes leaking. This can lead to loss of vision.
Anti-angiogenic ophthalmic agents are used to stop neovascularization in age related macular
degeneration.

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