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Treatment: Stroke Unit
Treatment: Stroke Unit
Treatment: Stroke Unit
loss of brain function(s) due to disturbance in the blood supply to the brain. This can be due
to ischemia (lack of blood flow) caused by blockage (thrombosis, arterial embolism), or a
hemorrhage (leakage of blood).[1] As a result, the affected area of the brain is unable to
function, leading to inability to move one or more limbs on one side of the body, inability to
understand or formulate speech, or an inability to see one side of the visual field.[2]
Treatment
[edit] Stroke unit
Ideally, people who have had a stroke are admitted to a "stroke unit", a ward or dedicated
area in hospital staffed by nurses and therapists with experience in stroke treatment. It has
been shown that people admitted to a stroke unit have a higher chance of surviving than those
admitted elsewhere in hospital, even if they are being cared for by doctors without experience
in stroke.[2]
When an acute stroke is suspected by history and physical examination, the goal of early
assessment is to determine the cause. Treatment varies according to the underlying cause of
the stroke, thromboembolic (ischemic) or hemorrhagic. A non-contrast head CT scan can
rapidly identify a hemorrhagic stroke by imaging bleeding in or around the brain. If no
bleeding is seen, a presumptive diagnosis of ischemic stroke is made.
An ischemic stroke is caused by a thrombus (blood clot) occluding blood flow to an artery
supplying the brain. Definitive therapy is aimed at removing the blockage by breaking the
clot down (thrombolysis), or by removing it mechanically (thrombectomy). The more rapidly
blood flow is restored to the brain, the fewer brain cells die.[82]
Other medical therapies are aimed at minimizing clot enlargement or preventing new clots
from forming. To this end, treatment with medications such as aspirin, clopidogrel and
dipyridamole may be given to prevent platelets from aggregating[30].
In addition to definitive therapies, management of acute stroke includes control of blood
sugars, ensuring the patient has adequate oxygenation and adequate intravenous fluids.
Patients may be positioned with their heads flat on the stretcher, rather than sitting up, to
increase blood flow to the brain. It is common for the blood pressure to be elevated
immediately following a stroke. Although high blood pressure may cause some strokes,
hypertension during acute stroke is desirable to allow adequate blood flow to the brain.
[edit] Thrombolysis
Intra-artial fibrinolysis, where a catherter is passed up an artery into the brain and the
medication is injected at the site of thrombosis, has been found to improve outcomes in
people with acute ischemic stroke.[87][original research?]
Another intervention for acute ischemic stroke is removal of the offending thrombus directly.
This is accomplished by inserting a catheter into the femoral artery, directing it into the
cerebral circulation, and deploying a corkscrew-like device to ensnare the clot, which is then
withdrawn from the body. Mechanical embolectomy devices have been demonstrated
effective at restoring blood flow in patients who were unable to receive thrombolytic drugs or
for whom the drugs were ineffective,[88][89][90][91] though no differences have been found
between newer and older versions of the devices.[92] The devices have only been tested on
patients treated with mechanical clot embolectomy within eight hours of the onset of
symptoms.
Angioplasty and stenting have begun to be looked at as possible viable options in treatment
of acute ischemic stroke. In a systematic review of six uncontrolled, single-center trials,
involving a total of 300 patients, of intra-cranial stenting in symptomatic intracranial arterial
stenosis, the rate of technical success (reduction to stenosis of <50%) ranged from 90-98%,
and the rate of major peri-procedural complications ranged from 4-10%. The rates of
restenosis and/or stroke following the treatment were also favorable.[93] This data suggests
that a large, randomized controlled trial is needed to more completely evaluate the possible
therapeutic advantage of this treatment.
Anticoagulation can prevent recurrent stroke. Among patients with nonvalvular atrial
fibrillation, anticoagulation can reduce stroke by 60% while antiplatelet agents can reduce
stroke by 20%.[96]. However, a recent meta-analysis suggests harm from anti-coagulation
started early after an embolic stroke.[97] Stroke prevention treatment for atrial fibrillation is
determined according to the CHADS/CHADS2 system.
If studies show carotid stenosis, and the patient has residual function in the affected side,
carotid endarterectomy (surgical removal of the stenosis) may decrease the risk of recurrence
if performed rapidly after stroke.
Patients with intracerebral hemorrhage require neurosurgical evaluation to detect and treat the
cause of the bleeding, although many may not need surgery. Anticoagulants and
antithrombotics, key in treating ischemic stroke, can make bleeding worse and cannot be used
in intracerebral hemorrhage. Patients are monitored and their blood pressure, blood sugar,
and oxygenation are kept at optimum levels.
Stroke rehabilitation is the process by which patients with disabling strokes undergo
treatment to help them return to normal life as much as possible by regaining and relearning
the skills of everyday living. It also aims to help the survivor understand and adapt to
difficulties, prevent secondary complications and educate family members to play a
supporting role.
Good nursing care is fundamental in maintaining skin care, feeding, hydration, positioning,
and monitoring vital signs such as temperature, pulse, and blood pressure. Stroke
rehabilitation begins almost immediately.
For most stroke patients, physical therapy (PT) and occupational therapy (OT) are the
cornerstones of the rehabilitation process, but in many countries Neurocognitive
Rehabilitation is used, too. Often, assistive technology such as a wheelchair, walkers, canes,
and orthosis may be beneficial. PT and OT have overlapping areas of working but their main
attention fields are; PT involves re-learning functions as transferring, walking and other gross
motor functions. OT focusses on exercises and training to help relearn everyday activities
known as the Activities of daily living (ADLs) such as eating, drinking, dressing, bathing,
cooking, reading and writing, and toileting. Speech and language therapy is appropriate for
patients with problems understanding speech or written words, problems forming speech and
problems with swallowing.
Patients may have particular problems, such as complete or partial inability to swallow,
which can cause swallowed material to pass into the lungs and cause aspiration pneumonia.
The condition may improve with time, but in the interim, a nasogastric tube may be inserted,
enabling liquid food to be given directly into the stomach. If swallowing is still unsafe after a
week, then a percutaneous endoscopic gastrostomy (PEG) tube is passed and this can remain
indefinitely.
Stroke rehabilitation should be started as quickly as possible and can last anywhere from a
few days to over a year. Most return of function is seen in the first few months, and then
improvement falls off with the "window" considered officially by U.S. state rehabilitation
units and others to be closed after six months, with little chance of further improvement.
However, patients have been known to continue to improve for years, regaining and
strengthening abilities like writing, walking, running, and talking. Daily rehabilitation
exercises should continue to be part of the stroke patient's routine. Complete recovery is
unusual but not impossible and most patients will improve to some extent : proper diet and
exercise are known to help the brain to recover.
Flaccid" redirects here. For the states of the half-erect penis or clitoris tissues, see
Tumescence.
Flaccid paralysis
Classification and external resources
ICD-10 G81.0, G82.0, G82.3
ICD-9 359.9
Contents
[hide]
1 Causes
o 1.1 Polio
o 1.2 Botulism
o 1.3 Other
2 References
3 External links
[edit] Causes
[edit] Polio
The term acute flaccid paralysis (AFP) is often used to describe a sudden onset, as might be
found with polio.
AFP is the most common sign of acute polio, and used for surveillance during polio
outbreaks. AFP is also associated with a number of other pathogenic agents including
enteroviruses, echoviruses, and adenoviruses, among others.[2]
[edit] Botulism
The Clostridium botulinum bacteria are the cause of botulism. Vegetative cells of C.
botulinum may be ingested. Introduction of the bacteria may also occur via endospores in a
wound. When the bacteria is in vivo, they induce flaccid paralysis. This happens because C.
botulinum produces a toxin which blocks the release of acetylcholine. When this occurs, the
muscles are unable to contract.[3]
[edit] Other
Flaccid paralysis can be associated with a lower motor neuron lesion. This is in contrast to a
upper motor neuron lesion, which often presents with spastic paralysis. Included in AFP's list
are Poliomyelitis (Polio), Transverse myelitis, Guillain-Barré syndrome, enteroviral
encephalopathy [4], traumatic neuritis, Reye's syndrome etc. An AFP Surveillance programme
is conducted to increase case yield of poliomyelitis. This includes collection of 2 stool
samples within 14 days of onset of paralysis and identification of virus. and control of the
outbreak and strengthening immunisation in that area.
Flaccid paralysis an abnormal condition characterized by the weakening or the loss of muscle tone.
It may be caused by disease or by trauma affecting the nerves associated with the involved muscles
Spastic Paralysis characterized by spasms and ↑ tendon reflexes of the muscle(s) in the paralyzed
region, due to upper motor neuron disease
Synergist is a kind of muscle which performs, or assist in performing, the same set of joint motion as
the agonists. Synergists are muscles that act on movable joints . Synergists are sometimes referred
to as "neutralizers" because they help cancel out, or neutralize, extra motion from the agonists to
make sure that the force generated works within the desired plane of motion.