Professional Documents
Culture Documents
BACA Programme July 08
BACA Programme July 08
BACA Programme July 08
BRITISH ASSOCIATION
OF
CLINICAL ANATOMISTS
The Summer Scientific Meeting and Annual General Meeting of the Association
will be held at:-
The Liverpool Medical Institution, Mount Pleasant, Liverpool.
(Please note 10 minutes for oral communications with a further 5 minutes for
questions: Posters will be discussed as scheduled during the Tea/coffee/lunch
breaks. At the allotted time for each poster presenters MUST be beside their
poster to discuss it with delegates)
Please support colleagues presenting posters during the breaks between oral
presentations.
14. SETH, Ajai, Jai SETH, Harold ELLIS, Department of Anatomy, School of Biomedical and
Health Sciences, Guys Campus, King’s College London, U.K. Axial Torsion of Meckel’s
Diverticulum – A Case Report and Review of the Previous Publications.
15. MORRISON, Stuart, Janet REID, Richard DRAKE, Departments of Anatomy and
Radiology, Cleveland Clinic, Ohio USA. Obstetric MRI imaging of Foetal Anatomy.
20. DENNIS, Helen, Roger SOAMES, Centre for Anatomy and Human Identification, College
of Life Sciences, University of Dundee, Dundee, Scotland. The cervical internal carotid
artery and relation of the common carotid bifurcation to the hypoglossal nerve.
21. DELIEU, John,1 Nigel JOHN,1 Mike MAHON,2 Paul MULLINS,1 Hayley DERRICOTT,2
Ik Soo LIM,1 Rhys THOMAS1 1Bangor University and 2Keele University, UK. Magnetic
resonance imaging of an embalmed human head.
22. LO, William, Harold ELLIS, Department of Anatomy and Human Sciences, King’s
College London, Guy’s Campus, London, UK. The Circle Before Willis
23. OWENS, David, Heikki WHITTET Department of ENT, Department of ENT Singleton
Hospital, Swansea. The anterior ethmoid artery in sinus surgery. A discussion of the
anatomical variations found and a surgical approach to its management in epistaxis.
25. PHILLIPS Carla and Abayomi ODEKUNLE Anatomy Unit, Department of Preclinical
Sciences, Faculty of Medical Sciences , University of the West Indies, St. Augustine
Campus, Trinidad and Tobago. Morphological and Craniometrical studies of the
Agouti’s (Dasyprocta Leporina) skull
Close of meeting
ABSTRACTS
EDUCATIONAL
13. BURWELL, R Geoffrey1, Ranjit K AUJLA 1*, Alanah S KIRBY 1*, Peter H
DANGERFIELD2, Alan MOULTON 3, Ashley A COLE 1, Fran J POLAK1*, Roland K
PRATT1*, and John K WEBB1*, Centre for Spinal Studies and Surgery, Queen’s Medical
Centre, Nottingham, Children’s Hospital, University of Liverpool, and Department of
Orthopaedic Surgery, King’s Mill Hospital, Mansfield, UK. Leptin-hypothalamic
dysfunction of energy metabolism (bioenergetics) affecting a normal sympathetic
nervous system mechanism contributing to human trunk size in girls: expressed
asymmetrically and potentially pathogenic for adolescent idiopathic scoliosis
(Supported by AO)
Asymmetries in upper arm length (UAL) are evaluated by higher and lower
body mass index (BMI) subsets about means for three groups of girls age
11-18 years: 1) normals (n=274), 2) scoliosis screening referrals (n=137),
and 3) preoperative girls with adolescent idiopathic scoliosis (AIS) (n=110).
In lower BMI subsets: 1) preoperative girls show abnormally increased
asymmetry of UAL, and 2) in thoracic AIS of screened and preoperative
girls, UAL asymmetry is associated significantly with Cobb angle and
apical vertebral rotation. Higher and lower BMI subsets are likely to
separate girls with higher from those with lower circulating leptin levels. In
the lower BMI subset preoperative girls show abnormal UAL asymmetry
and relatively reduced pelvic and shoulder widths, suggesting all are linked
to lower circulating leptin levels. The UAL asymmetry is not explained by
hormonal mechanisms. Given that leptin signals energy stores (metabolic
fuel) to the hypothalamus, we hypothesize: 1) normal trunk size control is
dual, by hypothalamic neuroendocrine and neural mechanisms, the latter
via the sympathetic nervous system (SNS); and 2) AIS initiation results
from hypothalamic dysfunction of the neural mechanism (possibly
involving abnormality of a G-protein coupled receptor to leptin, or a
G-protein) with the SNS inducing potentially pathogenetic asymmetries in
vertebrae, ribs, ilia, and upper arms.
14. SETH, Ajai, Jai SETH, Harold ELLIS, Department of Anatomy, School of Biomedical and
Health Sciences, Guys Campus, King’s College London, U.K. Axial Torsion of Meckel’s
Diverticulum – A Case Report and Review of the Previous Publications.
Johann Friedrich Meckel, in 1809, described the anatomy and embryology
of this small bowel diverticulum, which bears his name. Meckel’s
diverticulum (MD) is the most common congenital abnormality of the
gastrointestinal tract, with a prevalence ranging from 1 to 4% of the
population. The large majority are clinically silent, and are incidentally
identified at surgery or at autopsy. Lifetime risk of complications is
estimated at 4%, most of these presenting in adults. It is these cases that can
cause problems to the clinician, as the diagnosis can be elusive, and
consequences extremely serious. We present a case of axial torsion of the
MD around it’s base; one of the rarest complications. Factors predisposing
to axial torsion of MD include the presence of mesodiverticular bands, a
narrow base, an excessive length, and associated neoplastic growth or
inflammation of the diverticulum. Once identified, prompt surgical excision
generally leads to an uncomplicated recovery. A retrospective review of all
cases, published in the English language, of axial torsion of Meckel’s
diverticulum was performed. This identified 24 cases, with the earliest case
published in 1952. The demographic details, clinical features,
investigations, operative diagnosis, surgical procedure and histopathology
are noted and discussed.
15. MORRISON, Stuart, Janet REID, Richard DRAKE, Departments of Anatomy and
Radiology, Cleveland Clinic, Ohio USA. Obstetric MRI imaging of Foetal Anatomy.
Ultrasound remains the initial and in most pregnancies the only needed
method for imaging of the foetal and maternal anatomy. MRI however
offers several advantages over ultrasound which together with improved
technical factors have increased the value of MRI imaging during
pregnancy. These advantages include a large field of view and exquisite
imaging of the brain that is not degraded by the skull bones. Normal brain
maturation following the chronological appearance of the sulci and gyri can
be dated from an atlas. Exquisite soft tissue contrast allows excellent
imaging of the entire foetal anatomy. For example the foetal liver can be
easily separated from the foetal lung in cases of congenital diaphragmatic
hernia. MRI is not operator dependant or degraded by maternal obesity or
oligohydramnios. All scans were obtained after 20 weeks gestation on a 1.5
Tesla magnet. The majority were performed to better image the central
nervous system for presumed brain and spine anomalies. Diaphragmatic
hernia identified by ultrasound can be confirmed by MRI and volumes of
the lung obtained to aid in the prognosis prior to delivery. The placenta and
maternal anatomy can also be imaged. Examples of normal foetal anatomy
and embryological errors will be presented.
20. DENNIS, Helen, Roger SOAMES, Centre for Anatomy and Human Identification, College
of Life Sciences, University of Dundee, Dundee, Scotland. The cervical internal carotid
artery and relation of the common carotid bifurcation to the hypoglossal nerve.
Carotid endarterectomy is the main preventative procedure for patients at
risk of ischaemic stroke. However, the reported rates of complications, such
as cranial nerve palsies, are high. The aim of the present study is to
determine the relationship of the common carotid bifurcation (CCB) and
course of the cervical part of the internal carotid artery (ICA) to bony and
soft tissue structures. Forty five carotid regions (12 males, 12 females) were
dissected, the course of the ICA described and distances from the CCB to
specific anatomical landmarks measured. Twenty nine (64%) specimens had
a straight ICA, 12 (27%) a curved ICA, 3 (7%) pronounced kinking of the
ICA and 1 (2%) a coiled ICA: in addition the ICA was medial to the
external carotid artery in 4 (9%) specimens. Based on the distance between
the CCB and sternoclavicular joint (SCJ) a ‘safe zone’ for the hypoglossal
nerve can be established. At the mean CCB-SCJ distance (100mm) the
hypoglossal was observed to lie within 15.5mm superior to the CCB in 5%
of specimens: the larger the distance the smaller the safe zone. This can be
extrapolated for use on patients undergoing carotid endarterectomy to
reduce the incidence of injuries to the hypoglossal nerve.
21. DELIEU, John,1 Nigel JOHN,1 Mike MAHON,2 Paul MULLINS,1 Hayley DERRICOTT,2
Ik Soo LIM,1 Rhys THOMAS1 1Bangor University and 2Keele University, UK. Magnetic
resonance imaging of an embalmed human head.
Embalmed human cadavers provide a rich source of teaching and research
material for health related, pathological and anatomical studies. However it
would be valuable to both utilise such specimens in conjunction with
imaging and volume rendered simulations as well as providing stand-alone
computerised images in situations where cadaveric material is inappropriate.
Previous CT and MR studies of embalmed material are scant and suggest
poor tissue differentiation. In this study a partially prosected formaldehyde
fixed head embalmed three years previously was scanned in the sagittal
plane at 0.5 mm3 resolution using a Philips Achieva 3 Tesla MRI scanner,
giving a high resolution DICOM data set. Preliminary observation showed
that tissue types and specific structures were clearly identifiable throughout
the head including differentiation of grey and white matter areas of the
brain. Observations were made easily manageable using public domain
software. In conclusion, we affirm that high resolution MRI may be utilised
with traditionally embalmed material to generate multi-planar data sets for
visualisation, segmentation, and volume rendering. A Virtual Environment
or Augmented Reality (AR) application is being developed as a potential
novel approach to supplement anatomy teaching, whereby external and
internal anatomy can be explored in three dimensions from any view point.
22. LO, William, Harold ELLIS, Department of Anatomy and Human Sciences, King’s
College London, Guy’s Campus, London, UK. The Circle Before Willis
Thomas Willis (1621-1675) is famous for the eponymous anastomotic
arterial supply to the human brain. However, was he the first person to
describe this important anatomical structure? We trace the history of
discovery of the intracranial arterial ramification in human from 4th century
BC, when Herophilus discribed the rete mirabile (“wonderful net”) in sheep,
which was later incorporated into Galen’s physiological scheme, illustrated
in Vesalius’s Tabulae Anatomicae Sex (1538) but eventually denied in De
Humani Corporis Fabrica (1543). Since then, Fallopius, Casserio and
Vesling made important contributions to the understanding of the blood
supply to the brain and Wepfer (1658) provided an accurate description of
the ‘circle’. However, it was not until 1664 that Willis provided the first
undisputably complete illustration of the structure in Cerebri Anatome with
the aid of illustrations by Christopher Wren, who later designed the St
Paul’s Cathedral. Despite not being the first person to describe the ‘circle’,
we suggest that Willis still deserves to be the bearer of this eponymous
structure.
23. OWENS, David, Heikki WHITTET Department of ENT, Department of ENT Singleton
Hospital, Swansea. The anterior ethmoid artery in sinus surgery. A discussion of the
anatomical variations found and a surgical approach to its management in epistaxis.
The Anterior ethmoid artery is one of the confluence of vessels that form
kiesselbachs plexus of the anterior nasal septum. During surgery to the
paranasal sinuses the artery is at risk of surgical trauma due to its position
within the ethmoid cells. Division of the artery at this site may result in
significant bleeding and because of the vessel intra-orbital course a serious
risk intra-orbital haemorrhage and potentially blindness. This presentation
will discuss the anatomy of the vessel and the variations in its intranasal
course which expose it to a risk of iatrogenic injury. We will also describe
the anatomical principles of surgical cessation of haemorrhage from the
anterior ethmoid artery via an external approach.
25. PHILLIPS Carla and Abayomi ODEKUNLE Anatomy Unit, Department of Preclinical
Sciences, Faculty of Medical Sciences , University of the West Indies, St. Augustine
Campus, Trinidad and Tobago. Morphological and Craniometrical studies of the
Agouti’s (Dasyprocta Leporina) skull
In a bid to sustain the efforts aimed at updating the data available to the field
of experimental animal studies on the Agouti, we carried out a pilot study
on the skull of this new arrival to the field of experimental animal studies. A
total number of ten agoutis were utilized for this study. These were obtained
from local animal farmers and hunters. Following deep anaesthesia with
xylazine and ketamine, animals were decapitated and the heads immersed in
water for hot water maceration. The heads were then heated to a temperature
of 80°C for 30 minutes and subsequently placed under cold running tap
water. The eyes were enucleated and the skin and muscle carefully peeled
off the skull, avoiding damage to the bone. The skulls were air-dried
preparatory to cranial and mandibular measurements. Parameters
corresponding to those used in previous studies such as skull length,
interorbital distance, bicondylar width, and cranial capacity were measured
with the aid of a vernier caliper, string and beads. The data were analyzed
using standard statistics, correlation coefficients and regression equations.
Variation was relatively high for some measurements. Basal length was
highly correlated with cranial capacity. Clinical significance of study will be
discussed.
POSTERS
1. SCOTT, Elizabeth, Roger SOAMES, Centre for Anatomy and Human Identification,
College of Life Sciences, University of Dundee, Dundee, Scotland. Variations in the
morphology of the abdominal aorta and lumbar arteries.
The morphology of the abdominal aorta and lumbar arteries was
investigated in 32 cadavers (14 male, 18 female). The level of aortic
bifurcation and origin of the median sacral artery; the level of origin of each
lumbar artery and aortic diameter at each level; and angle of origin and
diameter of each lumbar artery were determined. Mean aortic length (lower
border of T12 to the bifurcation) was 145.0mm, with the mean level of
bifurcation being at the lower border of L4: a median sacral was observed in
24 cadavers. Tapering of the aorta from T12 to L3 followed by an increase
until bifurcation was observed in both sexes. Only 11 specimens had four
pairs of lumbar arteries arising from the aorta, a further 11 had five pairs: in
10 specimens the lumbar arteries arose as a common trunk. The majority of
lumbar arteries arose at the level of the corresponding vertebral body or the
body above. The angle of origin of right and left lumbar arteries was
consistent, being posterolateral: common trunks arose perpendicular to the
posterior aorta. Lumbar artery diameters increased from first to fifth lumbar
artery. These results demonstrate a greater variation in lumbar artery
morphology than previously reported.
Electronic poster
8. BURWELL, R Geoffrey1, Ranjit K AUJLA 1*, Alanah S KIRBY 1*, Peter H
DANGERFIELD2, Alan MOULTON 3, Ashley A COLE 1, Fran J POLAK1*, Roland K
PRATT1*, and John K WEBB1*, Centre for Spinal Studies and Surgery, Queen’s Medical
Centre, Nottingham, Children’s Hospital, University of Liverpool, and Department of
Orthopaedic Surgery, King’s Mill Hospital, Mansfield, UK. The timing of chest growth
in screened and preoperative girls with adolescent idiopathic scoliosis revealed by
body mass index: relation to puberty, thoracic visceral growth and the evolutionary
acquirement of bipedal gait (Supported by AO)
Biacromial width for age in adolescent girls was relatively larger in higher,
than in lower, body mass index (BMI) subsets in each of three groups of
girls. Here we evaluate chest sizes for age anthropometrically as lateral and
anteroposterior (AP) diameters by higher and lower BMI subsets about the
means in two groups of girls age 11-18 years: 1) scoliosis screening referrals
(n=147), and 2) preoperative girls with adolescent idiopathic scoliosis
(n=122). Higher BMI subsets reveal: 1) chest lateral and AP size for age
relatively greater than in lower BMI subsets of both groups (chest lateral:
screened p=0.001, preoperative p<0.001; chest AP, screened p=0.015,
preoperative p<0.001)(analysis of variance with corrections for age); and 2)
relatively earlier menarche. The findings for chest lateral diameter by BMI
subset are similar to those for biacromial and biiliac widths in these groups
of subjects. An earlier puberty with estrogen secretion explains the
relatively larger chest diameters in the higher BMI subset. By analogy with
early skull growth, the driving force to increasing chest diameters may be
thoracic visceral growth. The relatively wide human ribcage was acquired in
human evolution with decoupling of head and trunk movements required for
efficient bipedal gait.
9. NISBET, Lee, Roger, SOAMES, Centre for Anatomy and Human Identification, College
of Life Sciences, University of Dundee, Dundee, Scotland. Innervation of the patella.
Anterior knee (patellofemoral) pain can result from overuse of the joint,
trauma or damage during surgery. An understanding of the origin and course
of nerves innervating the knee is paramount to reduce the risk of surgical
injury. Ten knees (5 left, 5 right) from nine cadavers (5 males and 4 females:
mean age 71 years) were examined. The infrapatellar branch of the
saphenous nerve (IPBSN) was identified and traced to the medial and
anterior aspects of the knee and proximal leg: in the midline of the patella it
divides into 2/3 branches which continue to the lateral aspect of the knee. In
5 knees a branch from the nerve to vastus medialis was observed running
with the descending genicular artery to the medial margin of the patella
within vastus medialis: no similar fibres were observed in either vastus
intermedius or lateralis. Whether fibres from the IPBSN or those within
vastus medialis are responsible for innervating the patella and relaying pain
could not be determined. Further detailed study of a larger number of knees
is required before the likelihood of these nerves being involved in the
transmission of pain can be determined.
11. DENK Cem C., Department of Anatomy, Faculty of Medicine, Hacettepe University,
Ankara, Turkey. Cadavers From The Scope Of Religion And Law
The aim is to inform about the preparation of the cadavers, and the legal and
religious aspects of cadavers. The internet database was scanned. Related
official documents were studied. The experts of the subject were
interviewed. After researching the legal aspects of cadavers, related laws,
protocols and regulations were found. Laws no. 2238 and 2594 regulate
scientific studies on human corpses in Turkey. These laws regulate the
processes related to the corpses which are donated and bodies who are
unclaimed for, to be used in scientific university researches. These laws also
regulate the processes on the transportation, preservation, burial license of
the cadavers. According to the related laws and protocols, the bodies of
voluntary donators and bodies which are unclaimed for at least 6 months
can be used as cadavers. The bodies are buried according to appropriate
religious procedures after being used in scientific researches. When the
usage of human corpses for scientific research is analyzed from a religious
aspect, it can be observed that according to Christianity, Islam and the
Jewish religion it is acceptable to use cadavers. The only point to be taken to
account is that the body is treated with respect during the burial procedures.
12. DENK Cem C., Department of Anatomy, Faculty of Medicine, Hacettepe University,
Ankara, Turkey. Organ Donation From A Religious Point Of View
The study examines the religious aspect of organ donation. Data bases,
scientific articles and experts on the subject were scanned and interviewed.
In general, major religions point of view, in special, all world religions point
of view on the subject was analyzed. In general, it was observed that the
most authorized institutions of all religions supported organ donation.
However, since religion is a sociologically variant phenomenon and every
religion has many sects, it is impossible to reach an absolute result on the
subject. Religions in Turkey were used in the project. The declarations
about organ donation of the authorized institutions of Islam, Christianity and
Jewish religion in Turkey were examined. The results are, major sects of
Christianity (Orthodox, Protestant, Catholic) and Islam support organ
donation, while the Jewish religion supports organ donation in vital
situations but forbids it in any other case. These religions argue that the
human body has no individual state of belonging and that the body parts
gives life to others after death cannot be banned because it is a 'necessity'.
There has been negative and radical statements on the subject but these
statements do not represent the general approach of religious authorities on
organ donation.
13. TATAR Ilkan, Peter Cheng-te CHOU and Mehmet BİLGEN. Department of Radiology,
Medical University of South Carolina, Charleston,SC,USA. Imaging corticospinal tract
connectivity in injured rodent spinal cords using manganese-enhanced magnetic
resonance imaging.
In rodents, the CST lies between the dorsal horns next to the central canal.
Anatomical magnetic resonance imaging (MRI) do not produce CST
specific image contrast, but manganese-enhanced (MEI) offers a novel
neuroimaging tool to anterogradely trace the CST in rodents. The goal of
this presentation is to expand the current MEI capability further and test its
utility to image the axonal fiber connectivity in an injured SC. Contusion
type spinal cord injury (SCI) was produced on rats at T4 level and at
postinjury day 14, MnCl2 solution was delivered into the rat’s motor cortex
bilaterally. The injection site was subjected to electrical stimulation. Next
day, the animal was imaged using anatomical, MEI and diffusion tensor
imaging (DTI) modalities. In sections rostral to the injury, MEI depicted
signal enhancement confined spatially to the ventral-most part of the dorsal
funiculus between the dorsal horns of the gray matter. This enhanced region
overlapped exactly with the anatomical location of the CST in rodents. The
results demonstrate the feasibility of imaging fiber connectivity in
experimentally injured SC using MEI. This imaging approach may play
important role in future investigations aimed at understanding the
neuroplasticity in experimental SCI research.
14. CELIK Hakan Hamdi, Ilkan TATAR, Selcuk TUNALI and Muhammed Mustafa ALDUR.
Department of Anatomy, Hacettepe University Medical School 06100 Ankara,Turkey.
Creating Digital Anaglyph Images From Different Regions of Formalin Fixed
Cadavers and Their Usage on Anatomy Teaching and Examinations.
Cadavers are common materials of teaching for all departments as they
accelerate both graduate and postgraduate education. But the impossibilities
of body donation like tissue and organ donations in our country, we have to
go on with the present number of cadavers in the best efficient way for the
longest time. Just here we see the anaglyph technique in which the objects
are photographed from different viewpoints as stereopairs and then
perceived three dimensionally by using special filtered glasses.
Because of the organs in the body have close relationship each other and
they have a lot of different plane from superficial to deep, it must be imaged
and studied with carefully. The images taken from formalin-fixed cadavers
from two different viewpoints by anaglyph camera simultaneously, will be
processed in special software. Then they would be suitable for viewing with
anaglyph glasses. The images which will be held by this technique, would
be used as teaching and examination materials both in graduate and
postgraduate education activities. By this mean, more people would benefit
from limited number of cadavers and also it would be possible to have
cadaver based education outside the anatomy laboratory.
Electronic poster
15. BURWELL, R Geoffrey1, Ranjit K AUJLA 1*, Alanah S KIRBY 1*, Peter H
DANGERFIELD2, Alan MOULTON 3, Ashley A COLE 1, Fran J POLAK1*, Roland K
PRATT1*, and John K WEBB1*, Centre for Spinal Studies and Surgery, Queen’s Medical
Centre, Nottingham, Children’s Hospital, University of Liverpool, and Department of
Orthopaedic Surgery, King’s Mill Hospital, Mansfield, UK. Leptin-hypothalamic
mechanisms in the puberty of normal subjects: allocation of relatively less energy
stores (metabolic fuel) to skeletal growth in girls compared with boys (Supported by
AO)
There is a link between body fat and the timing of puberty with leptin
playing a permissive role. The coupling of skeletal growth to energy balance
involves leptin and Y2-receptors on neuropeptide Y hypothalamic neurons.
Here we evaluate skeletal sizes for age by higher and lower body mass
index (BMI) subsets about the means for normal boys (n=281) and girls
(n=274) age 11-18 years. Skeletal size for age by these higher and lower
BMI subsets for boys and girls shows respectively (p values, ANOVA with
correction for age): biacromial width <0.001, 0.036; biiliac width <0.001,
0.014; corrected standing height 0.046, 0.612; corrected sitting height 0.002,
0.058; lengths of upper arm 0.140, 0.832; forearm-with-hand 0.029, 0.769;
and tibia 0.265, 0.879. In higher than lower BMI subsets significantly
greater (very highly or highly) are 1) relative trunk widths of boys
(italicized above); and 2) the sex effect favoring boys for each of biacromial
width, biiliac width, corrected standing height, subischial height, and
lengths of upper arm, forearm-with-hand and tibia (ANOVA with correction
for age and sex). The hypothesis is suggested that in puberty
leptin-hypothalamic mechanisms allocate less energy stores (metabolic fuel)
to the growing skeleton in girls than boys, because of preparing for
pregnancy and lactation.
Electronic poster
16. DANGERFIELD P H. Mason C Jones L. An anomalous muscle in the forearm. The
University of Liverpool, UK
In the course of routine dissection of the upper limbs of a donated cadaver
in the Department of Human Anatomy and Cell Biology at Liverpool, an
unusual muscle arrangement was found in the flexor compartment of both
forearms. This was established as an anomaly of Palmaris longus. While
this variant is reported to be common, it is the first instance noted in the
Liverpool dissecting rooms by the staff. One of the first reports of a similar
variant was recorded by John Morrison in 1916 in a paper in the journal of
Anatomy and Physiology. Historically, this is interesting as Dr Roberts was
the pathologist at the Royal Southern Hospital in Liverpool where
orthopaedics was established by Robert Jones and the first radiologist Dr
Thurston Holland also practiced.
18. TATAR Ilkan, Peter Cheng-te CHOU and Mehmet BİLGEN. Department of Radiology,
Medical University of South Carolina, Charleston,SC,USA. Imaging corticospinal tract
connectivity in injured rodent spinal cords using manganese-enhanced magnetic
resonance imaging.
In rodents, the CST lies between the dorsal horns next to the central canal.
Anatomical magnetic resonance imaging (MRI) do not produce CST
specific image contrast, but manganese-enhanced (MEI) offers a novel
neuroimaging tool to anterogradely trace the CST in rodents. The goal of
this presentation is to expand the current MEI capability further and test its
utility to image the axonal fiber connectivity in an injured SC. Contusion
type spinal cord injury (SCI) was produced on rats at T4 level and at
postinjury day 14, MnCl2 solution was delivered into the rat’s motor cortex
bilaterally. The injection site was subjected to electrical stimulation. Next
day, the animal was imaged using anatomical, MEI and diffusion tensor
imaging (DTI) modalities. In sections rostral to the injury, MEI depicted
signal enhancement confined spatially to the ventral-most part of the dorsal
funiculus between the dorsal horns of the gray matter. This enhanced region
overlapped exactly with the anatomical location of the CST in rodents. The
results demonstrate the feasibility of imaging fiber connectivity in
experimentally injured SC using MEI. This imaging approach may play
important role in future investigations aimed at understanding the
neuroplasticity in experimental SCI research.
19. PORZIONATO Andrea, Veronica MACCHI, Carla STECCO, Cesare TIENGO, Enrico
VIGATO, Aldo MORRA, Anna PARENTI, Raffaele SCAPINELLI, Raffaele DE CARO
Department of Human Anatomy and Physiology, University of Padova, Italy Integrated
study of the vascularization of the infrapatellar fat pad
The present study focused on the vascularization of the infrapatellar fat pad,
which plays a pivotal mechanical role in the knee function. Twenty knees
from 20 cadavers (age range: 2 days – 77 years) were perfused with barium
sulphate suspension and resected. They were fixed, frozen, sectioned in
sagittal and coronal planes, and radiographed. Sections were also cleared by
the Spalteholz technique. Twenty-two other knees were studied in vivo
through CT angiographies to evaluate origin, number and calibre of arteries
irrorating the infrapatellar fat pad. Anatomical variations of the arteries of
the knee were quite frequently found. In 25% of cases, two middle genicular
arteries were present, the inferior one usually showing narrower calbre; in
30%, the middle genicular artery originated as a collateral of the lateral
superior geniculate artery. In newborns, the infrapatellar fat pad was
vascularized by the terminal branches of the middle geniculate artery,
medial inferior geniculate artery, lateral inferior geniculate artery and
anterior tibial recurrent artery which anastomose with each other. In adults,
vascularization of the fat pad by the anterior terminal branches of the middle
geniculate artery was reduced, due to involution of the infrapatellar septum.
20. H. Hamdi ÇELİK, BROHI R. A., TATAR I, ŞEN F., DENK C. C. Department of Anatomy,
Faculty of Medicine, Hacettepe University, Ankara, Turkey. A Mylohoid Anomaly
together with Bilaterally Duplication of Digastric Anterior Belly
An anomaly of the mylohyoid muscle during dissection of the submental
region was revealed together with a bilateral duplication of the anterior
bellies of the digastric muscles. The mylohyoid muscle had distinguishable
muscle fibers originating from mylohyoid raphe and coursing inferior to the
anterior bellies of the digastric muscles to the mylohyoid line. The anterior
bellies of the digastric muscle (ABDM) were duplicated bilaterally. Such a
complex variation of the mylohyoid and digastrics together has not been
previously reported in the literature. Moreover, such an organization of the
fiber groups of the mylohyoid has never been reported.
Electronic poster
23. BURWELL, R Geoffrey1, Ranjit K AUJLA 1*, Alanah S KIRBY 1*, Peter H
DANGERFIELD2, Alan MOULTON 3, Ashley A COLE 1, Fran J POLAK1*, Roland K
PRATT1*, and John K WEBB1*, Centre for Spinal Studies and Surgery, Queen’s Medical
Centre, Nottingham, Children’s Hospital, University of Liverpool, and Department of
Orthopaedic Surgery, King’s Mill Hospital, Mansfield, UK. The timing of trunk
widening in adolescent girls with scoliosis and in normals revealed by body mass
index: leptin-hypothalamic mechanisms allocate energy stores (metabolic fuel) to
puberty and the growing skeleton topographically mainly in the trunk (Supported by
AO)
Leptin, secreted by adipocytes, is a signal of energy sufficiency. It is master
hormone with many regulatory functions mediated through the
hypothalamus including appetite repression, initiation of puberty, control of
growth and reproduction, bone growth and formation both centrally through
the SNS and peripherally. Here we evaluate skeletal sizes for age by higher
and lower body mass index (BMI) subsets about the means for each of three
groups of girls age 11-18 years: 1) normals (n=274), 2) scoliosis screening
referrals (n=137), and 3) preoperative girls (n=110). Higher and lower BMI
subsets are likely to separate girls with higher from those with lower
circulating leptin levels. The higher BMI subsets reveal 1) biacromial and
biiliac sizes for age relatively larger than in the lower BMI subsets of all
three groups, and 2) relatively earlier menarche. In the higher BMI subsets
an earlier puberty with estrogen secretion explains the relatively larger trunk
width at shoulders and pelvis especially evident at the younger ages. These
findings for girls are consistent with 1) leptin-hypothalamic mechanisms
allocating energy stores (metabolic fuel) to the process of puberty and the
growing skeleton topographically mainly in the trunk, and 2) shoulder girdle
widening being driven mainly by lateral growth of the underlying ribcage.
Electronic poster
24. Veronica MACCHI, PORZIONATO Andrea, CLEMENTE Alberto*, MORRA Aldo**,
VIGATO Enrico, STECCO Carla, MACCHI Carlo, DE CARO Raffaele Dep. Human
Anatomy and Physiology, University of Padova; *Surgical, Anestetich and Radiologic
sciences, University of Ferrara; **Section od Radiology, Euganea Medica Center, Italy.
From the Virtuos Anatomy of Leonardo Da Vinci to the Virtual Anatomy of the
Radiological Bioimages
The aim of this study is to compare the anatomical drawings of Leonardo
Da Vinci and the radiological bioimages of 3D reconstruction of CT and
MR. 35 anatomical drawings of Leonardo have been selected from the
‘Codici di Anatomia’, Windsor Collection. 3D reconstruction of 30 CT and
10 MR have been performed, using a similar range of colour of Leonardo. A
good correspondence between the drawings of Leonardo and the
radiological bioimages has been obtained, also between some cross
sectional images of Leonardo and the corresponding radiological
reconstructions. Nowadays for the didactic purposes the 3D reconstrcution
obtained from CT and MR images can be used beside the anatomical
drawings and dissecting images, giving an optimal representation of the
morphology of the organs and a more intuitive visualisation of the deepness,
spatial orientation and topography of the structures.