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A Modified Steiners Analysis That Does Not Requir
A Modified Steiners Analysis That Does Not Requir
A Modified Steiners Analysis That Does Not Requir
DOI: 10.1111/ocr.12250
ORIGINAL ARTICLE
1
Department of Developmental
Biology, Harvard School of Dental Medicine, Structured Abstract
Boston, Massachusetts Objective: To correlate traditional Steiner’s skeletal and dental measurements to
2
Private Practice, Boston, Massachusetts
similar measurements that use the eyes and natural head position as references in-
3
The Forsyth Institute, Cambridge,
stead of the cranial base.
Massachusetts
4
Department of Orthodontics, University of Setting and Sample: One hundred and fifty-t wo lateral cephalometric radiographs
Illinois College of Dentistry, Chicago, Illinois (66 female and 86 male) from the Harvard Forsyth twin sample were included in the
Funding information convexity of the cornea together with natural head position as references instead of
NIH Blueprint for Neuroscience Research, the cranial base. A Pearson product-moment correlation coefficient was measured to
Grant/Award Number: (ROI DE 02873);
American Association of Orthodontics determine the correlation between the conventional Steiner’s analysis measure-
Foundation (AAOF) ments and the novel measurements relying on the eyes and natural head position.
Results: Steiner’s cephalometric measurements of the jaws to each other, the diver-
gency and the orientation of the incisors had a strong positive correlation with their
counterparts that relied on true horizontal and/or the eyes (P < 0.001).
Conclusion: The eyes and true horizontal can be used as alternatives to the cranial base
when diagnosing the relationship between the jaws and the position and orientation of
the teeth. Since the eyes and natural head position are identifiable without ionizing ra-
diation, future research should focus on the use of radiographic exposures limited to
the upper and lower jaws for orthodontic diagnosis and outcome assessment.
KEYWORDS
cephalometric analysis, cornea eyes, natural head position, orthodontic diagnosis, radiation
protection
1 | I NTRO D U C TI O N and orientation of the jaws and teeth to those of a comparable refer-
ence group.1 The sella-nasion (SN) plane is a horizontal reference in
Orthodontic records traditionally include panoramic radiographs the cranial base utilized by the most widely used cephalometric anal-
used to detect abnormalities in the teeth and surrounding struc- ysis (Steiner’s analysis).1 A point, the innermost point on the contour
tures, and cephalometric radiographs used to compare the position of the premaxilla, and B point, the innermost point on the contour
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in
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© 2018 The Authors. Orthodontics & Craniofacial Research Published by John Wiley & Sons Ltd
#16-0113). De-identified lateral cephalograms used in this inves- Each cephalogram tracing was then altered by substituting SN for a
tigation were collected from the Harvard Forsyth Institute growth true horizontal based on natural head orientation20 drawn through
18
sample database (1956-1983). a point corresponding to the maximum convexity of the cornea (C
The subject selection for this study was based on the availabil- point). After the tracings were altered, the following measurements
ity and quality of lateral cephalometric radiographs from which the were obtained as follows: TH-C A (°), TH-CB (°), ACB (°), TH-GoGn (°),
required landmarks could be adequately identified. Subjects that re- S-C (mm) U1-C A (mm), U1-C A (°), L1-CB (mm), L1-CB (°). All measure-
ceived orthodontic treatment were excluded from the study. ments were recorded in a Microsoft Excel spreadsheet (Microsoft
A post hoc power analysis was conducted with a clinically mean- Excel for Mac 2017; Version 15.33).
ingful difference set at 2 mm for linear measurements and 2-
5°
for angular measurements. The study sample size was sufficient in
2.3 | Reliability
finding these differences at 90% power, an alpha of 0.05 and use of
two-sided tests. To ensure an even distribution of pre-pubertal and Ten randomly selected lateral cephalograms were traced and as-
post-pubertal children and to check the stability of the cornea during sessed independently by the two examiners to evaluate inter-
the growth spurt, each of the 76 subjects (33 female and 43 male) observer reliability.
evaluated had two cephalograms traced. (age 8 years ± 12 months
and age 18 years ± 12 months).19 Each cephalogram was considered a
2.4 | Statistical analysis
separate sample resulting in a total sample of 152 and an average age
of 12 years and 6 months. Subjects were all of Caucasian ethnicity. Inter-examiner reliability was assessed using intraclass correlation
To report Caucasian reference measurements for the new anal- coefficients (ICCs). Paired sample t tests were used to compare the
ysis, subjects with an ANB of 2 ± 2° at age 18 were isolated to re- growth at the cornea point to the growth at nasion relative to sella
semble Steiner’s reference group (39 subjects, 20 males, 19 females). and to compare the change in traditional and new cephalometric
measurements between age 8 and 18. Two-t ailed t tests were used
to evaluate gender differences. A Pearson product-moment correla-
2.2 | Methodology
tion coefficient was used to determine the correlation between the
The digitized lateral cephalograms were uploaded to Dolphin Imaging conventional Steiner’s analysis measurements and the novel cepha-
software (Dolphin Imaging & Management Solutions, Chatsworth, lometric measurements containing C point.
CA), subsequently traced by two senior orthodontic residents (M.S.
and S.F.), and analysed using Steiner’s analysis. The following land-
3 | R E S U LT S
marks of interest were initially identified on each cephalogram: sella
(S), nasion (N), A point (A), B point (B), gonion (Go), gnathion (Gn),
3.1 | Inter-examiner reliability and growth between
the upper incisor root apex and crown tip; and the lower incisor root
age 8 and 18
apex and crown tip (Figure 1). Values for the following measure-
ments were obtained as follows: SNA (°), SNB (°), ANB (°), SN-GoGn Inter-examiner reliability was determined using intraclass correlation
(°), S-N (mm), U1-NA (mm), U1-NA (°), L1-NB (mm) and L1-NB (°). coefficients (ICCs) for each cephalometric measurement. ICCs calcu-
lated to assess the concordance of landmark identification between
the two examiners ranged from 0.915 to 0.996 (P < 0.001) demon-
strating excellent reliability. 21
The paired sample t test comparing S-N to S-C resulted in a P
value of 0.57 indicating no significant difference between growths
at nasion and the cornea during the growth spurt.
Table 1 reports means and standard deviations for all cephalo-
metric measurements for all the subjects. Table 2 reports normative
values at age 8 and 18 for the proposed analysis for the subjects that
had an ANB angle of 2 ± 2° at age 18. Most traditional and proposed
measurements had a statistically significant difference before and
after the growth spurt (Table 2). With the exception of SNA and SNB
at age 18, no significant gender differences were detected (Tables 3
and 4).
F I G U R E 1 Traditional and proposed measurements used in the The cephalometric measurements intended to assess the magnitude
study of jaw discrepancy, ANB and ACB, were very strongly correlated
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4 FINN et al.
TA B L E 1 Mean values of
Measurement Mean Standard deviation Minimum Maximum
cephalometric measurements (n = 152)
Traditional Steiner measurements
SNA 81.29 3.73 69.7 94.8
SNB 77.33 3.84 69.8 88.9
ANB 3.96 2.57 −4.7 9.2
SN-GoGn 33.5 5.29 20.2 48.5
U1-NA (°) 19.33 6.46 1 41.2
U1-NA (mm) 2.68 2.55 −3.4 8.8
L1-NB (°) 23.85 6.87 3.6 39.4
L1-NB (mm) 4.07 2.39 −2 11.8
Proposed measurements
TH-C A 95.33 4.23 83.4 110.3
TH-CB 88.79 2.96 82.5 98.4
ACB 6.5 3.08 −1.5 13.3
TH-GoGn 24.05 4.88 14.1 40.3
U1-C A (°) 14.91 6.95 −3.5 36.3
U1-C A (mm) 1.07 2.69 −4.9 7.2
L1-CB (°) 25.72 6.69 8.6 40.1
L1-CB (mm) 4.63 2.34 −0.9 12
C, maximum convexity of the cornea; A, A point; B, B point; Gn, gnathion; Go, gonion; L1, lower inci-
sor; N, nasion; S, sella; TH, true horizontal; U1, upper incisor.
(r = 0.943, P < 0.001; Figure 2). 22 Steiner’s mandibular plane angle measurements SNA and SNB showed weak correlations with TH-C A
SN-MP showed a strong positive correlation with the mandibular and TH-CB (r > 0.28, P < 0.001). All of Steiner’s dental cephalomet-
plane to true horizontal TH-MP (r = 0.697, P < 0.001). The angular ric measurements of inclination and position showed a very strong
TA B L E 2 Mean values of cephalometric measurements at age 8 and 18 for subjects that had an ANB angle of 2° ± 2 at age 18 (n = 39)
P Value
Mean at Standard Mean at Standard (Paired t Significance at
Measurement 8 y deviation Min Max 18 y deviation Min Max test) P < 0.01
C, maximum convexity of the cornea; A, A point; B, B point; Gn, gnathion; Go, gonion; L1, lower incisor; N, nasion; S, sella; TH, true horizontal; U1, upper
incisor.
FINN et al. |
5
TA B L E 3 Male and female mean values for traditional and proposed cephalometric measurements at age 8 for subjects that had an ANB
angle of 2° ± 2 at age 18 (n = 39, 20 males and 19 females)
P Value (t test)
Female Gender
Male mean Standard Mean at Standard difference at Significance
Measurement at 8 y deviation Min Max age 8 y deviation Min Max age 8 at P < 0.01
U1-NA (mm) 1.61 1.48 −1.6 4.6 35.63 3.28 28.3 41 0.575 NS
L1-NB (°) 21.28 5.33 13.7 31.5 35.63 3.28 28.3 41 0.310 NS
L1-NB (mm) 3.165 1.41 0.7 5.4 35.63 3.28 28.3 41 0.823 NS
Male and female normative values for proposed measurements at age 8
THCA 96.46 3.29 90 103.5 96.21 3.57 90.1 102.9 0.821 NS
THCB 89.495 2.92 83.6 95.1 88.58 2.74 83.7 92.3 0.322 NS
ACB 6.96 1.47 4.4 9.1 7.54 1.91 4.2 10.6 0.292 NS
TH-GoGn 24.76 3.73 19.9 33.2 24.25 4.76 15.1 31.5 0.710 NS
U1-C A (°) 14.01 4.93 5.9 23.1 24.25 4.76 15.1 31.5 0.521 NS
U1-C A (mm) 0.015 1.62 −2.3 3.4 24.25 4.76 15.1 31.5 0.700 NS
L1-CB (°) 23.035 5.49 15.3 32.3 24.25 4.76 15.1 31.5 0.208 NS
L1-CB (mm) 3.67 1.34 1.8 6.3 24.25 4.76 15.1 31.5 0.649 NS
C, maximum convexity of the cornea; A, A point; B, B point; Gn, gnathion; Go, gonion; L1, lower incisor; N, nasion; S, sella; TH, true horizontal; U1, upper
incisor.
positive Pearson correlation with their novel counterparts using the measurements evaluated were strongly or very strongly correlated
cornea instead of nasion (r > 0.95, P < 0.001; Figure 2). with the measurements that involved the eyes and natural head po-
sition instead of the cranial base (P < 0.001).
Although ANB and ACB had a near perfect correlation, the
4 | D I S CU S S I O N fact that SNA and SNB had weak correlations with their counter-
parts relying on the eyes and natural head position comes as no
The agreement in landmark identification between the two examin- surprise. The position of sella is known to be highly variable with
ers in this study was higher than that was reported by Uysal et al23 individual variations exceeding 10°. 25,26 Most clinicians are aware
who had ICC values ranging from 0.484 to 0.727. The inter-examiner of this individual variation in the cranial base and will often cor-
correlations seen in this study were more consistent with those rect measurements to SN using true horizontal when they notice
observed by Toy et al24 who presented correlation values between a sella that is too low or too high. This brings into question the
0.836 and 0.990 (P < 0.001 for both studies). diagnostic value of exposing the cranial base in the first place when
Pre and post pubertal evaluation indicated that the change in a non-r adiographic alternative is reproducible to within 1-3 ° even
the distance between nasion and sella was not statistically differ- 5 years after the original recording. 27 The relative stability of the
ent from the change in the distance between nasion and the cornea cranial base does make it useful for superimpositions to evaluate
point. It also showed that most of Steiner’s measurements and the treatment progress and outcomes. Further research is necessary
measurements proposed in this study were significantly different to validate the use of the eyes and natural head position for those
before and after puberty that is why separate standards for the new applications.
analysis were reported for age 8 and 18. A clinical judgement based An obvious limitation is the two-d imensional nature of the
on developmental age and the appearance of secondary sexual char- records used. However, the intent of this study is clearly not to
acteristics can be made to decide whether to compare a growing trace the eyes on cephalometric radiographs but to prove the
patient to pre-pubertal or post-pubertal reference values. concept that the eyes along with natural head position can be
The results of the cross-sectional investigation demonstrate that used for orthodontic diagnosis as an alternative to the cranial
Steiner’s ANB angle, mandibular plane angle and all of the dental base. Since the eyes and natural head position can both be
|
6 FINN et al.
TA B L E 4 Male and female mean values for traditional and proposed cephalometric measurements at age 18 for subjects that had an ANB
angle of 2° ± 2 at age 18 (n = 39, 20 males and 19 females)
P Value (t Test)
Gender
Male Mean Standard Female Mean Standard difference at Significance
Measurement at 18 y deviation Min Max at age 18 y deviation Min Max age 18 at P < 0.01
C, maximum convexity of the cornea; A, A point; B, B point; Gn, gnathion; Go, gonion; L1, lower incisor; N, nasion; S, sella; TH, true horizontal; U1, upper
incisor.
identified without the need for radiation using 2D or 3D facial used as the reference to measure the position of the jaws, teeth
photographs, this concept could allow limiting the radiographic and the divergency (Figure 3). Recent studies have established
field of view needed for orthodontic diagnosis and outcome as- reference values for measurements that use of the eyes and
sessment. For example, 2D or 3D radiographic exposure limited natural head position as references for 3D surface imaging and
to the upper and lower jaws can be registered to a 2D or 3D fa- tested them on orthodontic patients yielding results in agree-
cial photograph, and a true horizontal through the cornea can be ment with the ones in this paper. 28,29
F I G U R E 3 Demonstration of how a limited field of view radiographic exposure can be indexed to a photograph to perform the proposed
analysis
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