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Practical 1 Genetics
Practical 1 Genetics
Practical 1 Genetics
Practical Genetic
PRACTICAL REPORT
PRACTICAL NUMBER :1
A genotype is the set of genes that make up an individual. The phrase can also
apply to the two alleles that are inherited for a certain gene. When the information
encoded in the genes' DNA is used to generate protein and RNA molecules, the
genotype is expressed. The expression of the genotype contributes to the phenotype,
or observable traits, of a person (Christopher, n.d.). Many genes are presented twice
since humans have a homologous pair of each chromosome, generally one from each
parent, maternal and paternal.
Each time a cell multiplies, this initial genetic material is duplicated, ensuring that
all cells have the identical DNA. The division process of the cell called mitosis. Genes
contain the instructions for the cell to create proteins, which result in distinct physical
characteristics. Alleles are variations in the sequence of these genes; one allele may be
dominant while the other is recessive, and different alleles may interact in a number of
ways depending on which chromosome they are on, resulting in a broad range of
phenotypic consequences (Greenwood, 2021).
2.0 OBJECTIVES
1. To examine a few characters that is known to be controlled by your genes.
2. To identify and characterize the various visible traits in the human body.
3.0 MATERIAL AND METHOD
1. The following ranges of characters in the human body were studied:
Dominant Recessive
No Character
Allele Phenotype Allele Phenotype
1 Earlobe attachment E Free earlobes e Attached earlobes
2 Bent little finger B Bent little finger b Straight little finger
3 Mid-digital hair M Mid digital hair m No mid-digital hair
4 Tongue roller T Can roll tongue t Can’t roll tongue
5 Widow’s peak W Has peak w Lacks peak
6 Hitchhiker’s thumb H Hitchhiker’s thumb h Normal thumb
7 Dimples D Dimple present d No dimples
Short hallux (big
8 A Shorter hallux a Longer hallux
toe)
9 Eye colour B Eyes not blue b Blue eyes
10 Handedness R Right-handed r Left-handed
Hand clasping
11 L Left thumb on top l Right thumb on top
(Interlaced fingers)
12 Forelock F White forelock f No white forelock
13 Darwin’s tubercle N Has tubercle n No tubercle
14 Chin Cleft C Cleft chin c Smooth chin
15 Achoo syndrome S Sneezing s Not sneezing
4.0 RESULT
Table 1: The number of students in the class having dominant and recessive
phenotype in each characteristic
Table 1 shows the number of students in the class that having dominant and
recessive phenotype for each of the characteristics. Students that have free earlobes
are higher than students with attached earlobes. The number of students that can bent
little finger are 25 while students that have straight little finger are 46. Next, number of
students with mid-digital hair and shorter hallux which are dominant, are both 38
students while others with no mid-digital hair and longer hallux which are recessive, are
both 33 students. The number of students that can roll their tongue are higher than
student who cannot roll their tongue. More, there are only 28 students who have
Hitchhiker’s thumb while the other 43 students have normal thumb. The number of
students who has Darwin’s tubercle and no tubercle are 35 and 36 respectively.
Students who have dimple are minority number in the class where there are only 23
students, while 48 students have no dimples. There are no students with blue eyes in
the class. For number of students that have white forelock is only one person while the
other 70 students have no white forelock. Furthermore, majority number of students in
the class are right-handed. For students who has Widow’s peak are 13 students and
students with lack peak are 58 students. Next character is hand clasping (interlaced
fingers), there are 47 students who their left thumb on top and 24 students for right
thumb on top. Finally, for students with dominant phenotype in having cleft chin and
sneezing achoo syndrome are same where both have 9 students, whereas for students
with recessive phenotype in having smooth chin and not sneezing are also same with
both having 62 students.
Graph 1: The percentage of students in the class having dominant and recessive
phenotype in each characteristic
5.0 DISCUSSION
5.1 Earlobe attachment
An earlobe is made up of connective tissues, areola tissues, and fat cells mixed
together. Earlobes have a healthy blood supply, which helps them stay warm and in
balance. Free earlobes and connected earlobes are the two main forms of earlobes
found in humans (Khetrapal, 2021). There are some people have unattached earlobes,
which curve up between the lowest point of the earlobe and the point where the ear
joins the head, as illustrated in the left of the image above. Other people have attached
earlobes, which merge in with the side of the head, as depicted in the right of the
image above (McDonald, 2011). Based on the result, 48 students which 67.61% of the
class have unattached earlobes while 23 students which is 32.39% of the class have
attached earlobes. Unattached earlobes were found to be dominant over attached
earlobes in one of the first earlobes studies (Wu, 2010). Unattached earlobes occur as a
result of a dominant allele's effect. The offspring will be born with unattached earlobes
if both parents' genes exhibit the dominant allele or one of the parents express
dominant allele and the other parent express recessive allele. If a baby with attached
earlobes is born to parents with unattached earlobes, both parents will have a copy of
the dominant and recessive gene.
Figure 2: straight little finger (left) and bent little finger (right).
(Bio- Packet- Evolution, n.d.)
According to mythology, little fingers can be split into two categories which are
bent and straight as shown in the picture above. The trait is controlled by a single gene
with two alleles, with the dominant allele for B and the recessive allele for b. A
dominant allele results in the end joint of the little finger of each hand bending inward
(McDonald, 2011). Straight little fingers are a result of the recessive genotype. Based
on the researchers, only four patients out of a total of 4,304 were found to have bent
little fingers (Marden et al., 1964). Based on the result, there are 25 students (35.21%)
in the class have bent little finger while 46 students (64.79%) in the class have straight
little finger. People may inherit the dominant allele (B) that encodes for bent little finger
and the recessive allele (b) that encodes for straight little finger. An individual inherits
one set of genes from their mother and another set from their father, forming a
complete set of alleles, whether BB (homozygous dominant), Bb (heterozygous
dominant) or bb (recessive).
5.7 Dimples
The majority of researchers consider dimples a dominant genetic trait, meaning
that one copy of the altered gene in each cell is sufficient to cause dimples
(Wiedemann, 1990). The most prevalent facial feature is dimples, which are a dominant
trait, that is inherited from a single gene (Kosif, 2015). The analysis shows that 32.39%
of students in 71 students of a class have dimple. Dimple-prone people may inherit the
dominant allele (D) that encodes for dimples and the recessive allele (d) that encodes
for smooth skin or no dimples or inherit both dominant allele (D) from both parents. An
individual inherits one set of genes from their mother and another set from their father,
forming a complete set of alleles, whether DD (homozygous dominant), Dd
(heterozygous dominant) or dd (recessive). The chances of their offspring inheriting the
same dominant trait (dimples) are very high if both parents display the same
characteristic (Schulman, 2019). A child will not have dimples if neither parent has
them, unless a spontaneous mutation occurs. A child who inherits the dimple gene from
one or both of the parents has a 25%-50% chance of inheriting the gene. Both parents
who have dimples have a 50%-100% chance of passing that gene onto the child,
depending on how the dimple genes were inherited (Kosif, 2015).
In the same way as other characteristics, the factor for relatively long hallux is
recessive from the one for relatively long second toe (Kaplan & Powell, 1964). Although
Morton's toes are genetically linked, their inheritance does not conform to the simple
dominant-recessive model (Aigbogun et al., 2019). Based on the result, 46.48%
individuals have longer hallux (aa) while 53.52% individuals have shorter hallux (Aa or
AA). Carrier of autosomal recessive allele (a) condition among parents causes a
condition where each parent has one recessive gene and one dominant gene that gives
the potential to pass the recessive trait on to the child. Genetic traits or conditions can
be passed down from parent to child through autosomal recessive inheritance, where a
child inherits one copy of each mutated gene from each parent. Short hallux makes it
obvious that the individual has a longer second toe. This condition is known as morton’s
toe as shown in Figure 4 The length of the big toe and the length of the second toe
are determined genetically but may be influenced by more than one gene or by a
combination of genetics and environment.
Figure 5: left thumb on top (left) and right thumb on top (right)
(Syrovatkina, 2019)
The position of the hand clasping whether the left thumb on top (L) or right
thumb on the top (l) does not relate with the handedness or major sexual dimorphism
(Lutz, 1908). Based on the result, there are 47 people, who is equal to 66.20% in the
class, who put their left thumb on top while the others put their right thumb on top.
Right thumb on top may result from acquiring two recessive copies, or alleles of the
genes (ll) that determine the position of the thumb. The trait of the hand clasping was
inherited from both parents to their children. The mating of both left thumb on top (L x
L) produces more left thumb offspring than the mating of both right thumb on top (l x
l). However, over a third of the children of l x l matings are L (Reiss, 1999). This
happens because whether both parents may not have the dominant genotype, (LL or
Ll), their children might have the dominant genotype. This kind of condition might occur
because the dominant allele (L) is over the recessive allele (l).
5.12 Forelock
Forelock is an autosomal dominant genetic disorder with the majority of those
affected having a white patch of hair near the forehead. Forelock may be caused by
genetic mutations that affect melanin production. Forelock is an autosomal dominant
genetic disorder, which means that 50 percent of those affected by forelock will pass
the condition on to their offspring (Smith, 2018). Based on the result, only 1 person
(1.41%) has a forelock while the other 70 people (98.59%) do not have a forelock.
Forelock is an autosomal dominant genetic. If the mother or father has the dominant
allele (F), they children will surely inherit the forelock trait.
Gene for cleft chin is C and the gene for smooth chin is c. Because cleft chin is a
dominant trait, possessing the dominant allele from either one parent (Cc) or both
parents (CC) will always result in the phenotype associated with the dominant allele
(Pelz, n.d.). Based on the result, there are 12.68% people with a cleft chin while the
other 87.32% have a smooth chin. It clearly shows that the data was contrary to the
theory that cleft chin is dominant over smooth chin. It is equally possible for someone
with a cleft chin to have two dominant alleles or one dominant allele and one recessive
allele. Each of the children will inherit a dominant phenotype if both copies of the gene
are dominant. They will very certainly have cleft chins. If a person has one dominant
cleft gene and one recessive cleft gene, their children will have an equal chance of
having a cleft chin or a smooth chin. This implies that each of the offspring has a 50%
chance of developing a cleft chin. If a recessive gene is passed down from a mother or
father, the form of their children's chin is determined by which genes the other spouse
possesses. If the child gets another recessive gene, their chin will most likely be smooth
and while if the child gets a dominant gene, they will most likely have a cleft chin or
smooth chin (Dorman, 2007).
6.0 CONCLUSION
Genetics is the field of biology that studies DNA of organisms, how it appears as
genes, and how those genes are passed down through generations. Genes contain the
instructions for the cell to create proteins, which result in distinct physical
characteristics and different alleles may interact in several ways depending on which
chromosome they are on, resulting in a broad range of phenotypic consequences. There
are eight characteristics that have higher percentage of recessive phenotype which are
straight little finger, lack of Widow’s peak, has Hitchhiker’s thumb, has no dimples, has
no white forelock, no tubercle, has smooth chin and not sneezing (no achoo syndrome).
The other seven characteristics are higher in percentage of dominant phenotype which
had free earlobes, mid digital hair, can roll their tongue, has shorter hallux, do not have
blue eyes, right-handed, and have interlaced fingers where the left thumb on top.
Majority number of students in the class are having recessive genotype than dominant
genotype.
7.0 REFERENCE
Aigbogun, E. O., Alabi, A. S., Didia, B. C., & Ordu, K. S. (2019). Morton's toe:
Prevalence and inheritance pattern among Nigerians. International Journal of
Applied and Basic Medical Research, 9(2), 89.
Bio- Packet- Evolution. (n.d). Google Docs. Retrieved from
https://docs.google.com/document/d/1N68s4SOjqhyBWc5aQOC92ZKQU6uDP10
HZaS4BxNQjKg/edit
Breitenbach, R. A., Swisher, P. K., Kim, M. K., & Patel, B. S. (1993). The photic sneeze
reflex as a risk factor to combat pilots. Military medicine, 158(12), 806-809.
Christopher P. (n.d.). Genetic Glossary: Genotype. Genome.Gov. Retrieved from
https://www.genome.gov/genetics-glossary/genotype
Coren, S. (1995). Family Patterns in Handedness: Evidence for Indirect Inheritance
Mediated by Birth Stress. Behavior Genetics. Vol 25, p 517–524.
Darwin’s tubercle - General Practice Notebook. (2018). GP Notebook. Retrieved from
https://gpnotebook.com/simplepage.cfm?ID=832176200
Dorman, L. (2007). Understanding Genetics. The Tech Interactive. Retrieved from
https://genetics.thetech.org/ask/ask240
Eiberg, H., & Mohr, J. (1996). Assignment of genes coding for brown eye colour (BEY2)
and brown hair colour (HCL3) on chromosome 15q. European Journal of Human
Genetics, 4(4), 237-241.
Forrester, J. M. (1985). Sneezing on exposure to bright light as an inherited response.
Human heredity, 35(2), 113-114.
Grant, M. D., & Lauderdale, D. S. (2002). Cohort effects in a genetically determined
trait: eye colour among US whites. Annals of human biology, 29(6), 657-666.
Greenwood, M. (2021). What is Genetics? News-Medical.Net. Retrieved from
https://www.azolifesciences.com/article/What-is-Genetics.aspx
Hammond, C. (2018). Do you inherit the ability to roll your tongue? BBC Future.
Retrieved from https://www.bbc.com/future/article/20180130-do-you-inherit-
the-ability-to-roll-your-tongue
Hecht, M. (2019). What Exactly Is Morton’s Toe? Healthline. Retrieved from
https://www.healthline.com/health/mortons-toe
Is Eye Color Genetic? | What Your Eye Color Has to Do With Your History. (2021).
Luna. Retrieved from https://www.lunadna.com/is-eye-color-genetic/
Kaplan, A. R., & Powell, W. (1964). Genetics of Relative Toe Lengths1. Acta geneticae
medicae et gemellologiae: twin research, 13(3), 295-304.
Khetrapal, A. (2021). Genetics of Earlobes. News-Medical.Net. Retrieved from
https://www.news-medical.net/health/Genetics-of-Earlobes.aspx
Kosif, R. (2015). Anatomical skin dimples. Innov J Med Health Sci, 5, 15-8.
Lutz, F. E. (1908). The inheritance of the manner of clasping the hands. The American
Naturalist, 42(495), 195-196.
Marden, P. M., Smith, D. W., & McDonald, M. J. (1964). Congenital anomalies in the
newborninfant, including minor variations: A study of 4,412 babies by surface
examination for anomalies and buccal smear for sex chromatin. The Journal of
pediatrics, 64(3), 357-371.
McDonald, J. H. (2011). Myths of Human Genetics: Earlobes. Myths of Human
Genetics. Retrieved from https://udel.edu/%7Emcdonald/mythearlobe.html
McDonald, J. H. (2011). Myths of Human Genetics: Bent Little Finger. Myths of Human
Genetics. Retrieved from https://udel.edu/%7Emcdonald/mythbentpinkie.html
McDonald, J. H (2011). Myths of Human Genetics: Mid-digital Hair. Myths of Human
Genetics. Retrieved from https://udel.edu/%7Emcdonald/mythdigithair.html
McDonald, J. H (2011). Myths of Human Genetics: Tongue Rolling. Myths of Human
Genetics. Retrieved from https://udel.edu/%7Emcdonald/mythtongueroll.html
Mendelian Inheritance. (2021). FlexBooks 2.0. Retrieved from
https://flexbooks.ck12.org/cbook/ck-12-biology-flexbook-
2.0/section/3.11/primary/lesson/mendelian-inheritance-in-humans-bio/
Pelz, B. (n.d.). Human Genetics | Introductory Psychology. Lumen Learning. Retrieved
from https://courses.lumenlearning.com/suny-hccc-ss-151-1/chapter/human-
genetics/
Pietrangelo, A. (2019). Does Having a Widow’s Peak Tell Me Anything About My
Genetics? Healthline. Retrieved from https://www.healthline.com/health/widows-
peak#causes
Pratt, V. M., McLeod, H. L., Rubinstein, W. S., Scott, S. A., Dean, L. C., Kattman, B. L.,
& Malheiro, A. J. (2012). Medical genetics summaries [Internet].
Reiss, M. (1999). The genetics of hand-clasping a review and a familial study. Annals of
human biology, 26(1), 39-48.
Rubio, O., Galera, V., & Alonso, M. C. (2015). Anthropological study of ear tubercles in
a Spanish sample. Homo, 66(4), 343-356.
Schulman, J.S. (2019). Why Do Some People Have Cheek Dimples? Healthline.
Retrieved from https://www.healthline.com/health/cheek-dimples#genetics
Smith, L. M. (2018). What is piebaldism and what causes it? Medical News Today.
Retrieved from https://www.medicalnewstoday.com/articles/320561#what-is-
piebaldism
Spinney, L. (2008). Remnants of evolution. New Scientist, 198(2656), 42-45.
Starr, B. (2004). Understanding Genetics. Dominant vs. Recessive. The Tech
Interactive. Retrieved from https://genetics.thetech.org/ask/ask22
Syrovatkina, A. (2019). The Way You Cross Your Fingers Shows What Kind of Person
You Are. Bright Side Inspiration. Creativity. Wonder. Retrieved from
https://brightside.me/inspiration-psychology/the-way-you-cross-your-fingers-
shows-what-kind-of-person-you-are-794376/
10 Human Genetic Traits of Simple Inheritance: Which Do You Have? - Page 2. (2017).
10 Human Traits of Simple Inheritance. Retrieved from
https://www.scienceprofonline.com/genetics/ten-human-genetic-traits-simple-
inheritance-2.html#:%7E:text=9.,absence%20of%20hair%
What causes some people to be left-handed, and why are fewer people left-handed
than right-handed? (2004). Scientific American. Retrieved from
https://www.scientificamerican.com/article/what-causes-some-people-t/
Whelan, C. (2019). Hitchhiker’s Thumb. Healthline. Retrieved from
https://www.healthline.com/health/hitchhikers-thumb#associated-conditions
Wiedemann, H. R. (1990). Cheek dimples. American journal of medical genetics, 36(3).
Wu, D. (2010). Understanding Genetics. The Tech Interactive. Retrieved from
https://genetics.thetech.org/ask/ask372