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Diagnosis and Evaluation of Eating Disorders in The Pediatric Patient
Diagnosis and Evaluation of Eating Disorders in The Pediatric Patient
E
ating disorders are challeng- screening recommendations for these complications such as gastrointestinal
ing to diagnose in the pediatric disorders. obstruction by formation of bezoar or
population, as these disorders perforation of the stomach or intestines,
can have an insidious onset and those PICA heavy metal poisoning caused by the
suffering can have limited insight into Pica is an eating disorder that in- ingestion of metal-based substances, or
their illness. Due to the high prevalence volves eating items over a period of infections such as toxoplasmosis and
of these disorders and the associated at least 1 month that are not typical- toxocariasis.2,3 Although pica is more
morbidity and mortality, it is critical ly thought of as food and that do not common in pregnant women and chil-
that pediatricians accurately diagnose contain significant nutritional value. dren, prevalence in the general popula-
these conditions as early as possible. Non-nutritive foods could include pa- tion is unknown.4
This article provides a review of the per, soap, cloth, hair, string, wool,
current diagnostic criteria for eating soil, chalk, talcum powder, paint, gum,
disorders included in the Feeding and metal, pebbles, charcoal, ash, clay, RUMINATION DISORDER
Eating Disorders section of The Diag- starch, or ice. Pica can occur at any Rumination disorder (RD) involves
nostic and Statistical Manual of Men- age and gender, although the diagnosis the regular regurgitation of food that oc-
tal Disorders, fifth edition (DSM-5),1 is not made in children younger than curs for at least 1 month. Regurgitated
and discusses initial evaluation and age 2 years to exclude developmen- food can be re-chewed, re-swallowed,
or spit out. When someone regurgitates
Briana Sacco, MD, is an Assistant Professor of Psychiatry, Division of Child and Adolescent Psychiatry, their food, they do not appear to be try-
University of Texas Southwestern Medical Center; and the Medical Director, Center for Pediatric Eating ing to do so, nor do they appear to be
Disorders, Children’s Medical Center Plano, Children’s Health. Urszula Kelley, MD, CEDS, is a Professor of stressed, upset, or disgusted. Medical
Psychiatry, Division of Child and Adolescent Psychiatry, University of Texas Southwestern Medical Cen- etiologies, including gastrointestinal
ter; a Child Psychiatrist, Center for Pediatric Eating Disorders, Children’s Medical Center Plano, Children’s conditions, must be excluded before
Health; and the Director of Psychiatric Services, Children’s Medical Center Plano, Children’s Health. this diagnosis is made, and a child can-
Address correspondence to Briana Sacco, MD, Children’s Medical Center Plano, Children’s Health, not have this diagnosis concurrently
7601 Preston Road, Suite P4300, Plano, TX, 75024; email: briana.sacco@utsouthwestern.edu. with another eating disorder diagnosis
Disclosure: The authors have no relevant financial relationships to disclose. (such as avoidant restrictive food intake
doi:10.3928/19382359-20180523-02 disorder [ARFID], anorexia nervosa
[AN] or bulimia nervosa [BN]). RD, if type is general food aversion. These experience. This type can present in
severe enough to warrant independent children typically eat a small amount of a child of any age, from infancy into
clinical attention, can be diagnosed in food, and this is a pattern that develops adulthood.1,5,6
the presence of another mental disor- by age 3 years. These children may not
der, including intellectual disability.1 recognize hunger sensations, frequent- Concurrent Medical Condition
Prevalence of RD in the general popu- ly demonstrate a lack of interest in food The fourth and final type is a concur-
lation is unknown.4 or eating, and often they would rather rent medical condition. These children
play or talk than eat. Given reduced can develop food refusal or inadequate
AVOIDANT RESTRICTIVE FOOD nutritional intake, these children are at intake at any age, and these behaviors
INTAKE DISORDER risk for significant growth deficiency, may come and go depending on the
Children suffering from ARFID often exhibiting both weight and height medical condition contributing to the
present with avoidance or restriction deficiencies. For some children, these symptoms. These children will typi-
of food intake resulting in clinically restrictive eating behaviors will persist cally initiate feeding but may become
significant failure to meet nutritional into adulthood.1,5,6 distressed or refuse to continue eating.
requirements. To meet DSM-51 criteria, Based on the child’s medical experience
children present with at least one of the Sensory Food Aversion (eg, constipation causing cramping ab-
following features: weight loss (or lack The second type is sensory food dominal pains, gastroesophageal reflux
of expected weight and height gains for aversion, in which a child may refuse to causing sharp stomach pains), these
age and gender), significant nutritional eat foods due to specific taste, texture, children associate discomfort with food
deficiency or health impact, depen- temperature, or smell experiences that and eating, and this is thought to con-
dence on enteral feeding or oral nutri- are aversive to the child. These children tribute to the development of avoidant
tional supplements for growth, and/or will demonstrate food refusal after in- eating behaviors. Medical management
marked interference with psychosocial troduction of a new or different type of of these children may improve their
functioning. The children do not ex- food that is aversive to the child, and symptoms but will not fully resolve
press concerns about body weight or subsequently that child may general- their avoidant eating behaviors, and as
shape. Exclusion criteria include devel- ize this aversion and refuse other foods a result they will continue to struggle
opmentally normal picky eating behav- with similar color, appearance, or smell. with adequate weight gain.1,5,6
iors and culturally or religiously sanc- These children will eat preferred foods Although ARFID has been observed
tioned practices. Before the diagnosis without difficulty, so they may dem- by medical and mental health providers
can be made, medical etiologies must onstrate specific dietary deficiencies for years, the diagnosis was formalized
be excluded.1 depending on their eating preferences, in DSM-51 in 2013, so epidemiological
but may not show any signs of overall data are limited. Prevalence of ARFID
General Food Aversion growth deficiency. These children tend in children treated for eating disorders
The DSM-51 diagnostic criteria for to present in the first decade of life, al- in the tertiary care setting ranges from
ARFID is quite broad, but character- though their symptoms may also persist 5% to 22%.6-8 One cohort of 13-year-
istic subtypes have been described and into adulthood.1,5,6 old adolescents screened for ARFID
are helpful to keep in mind in the con- in Switzerland had 3% prevalence of
text of clinical presentation and diag- Posttraumatic Feeding Disorder ARFID symptoms. Of these children
nostic formulation. In considering the The third type is posttraumatic feed- with ARFID symptoms, 39% reported
most common clinical presentations ing disorder, in which a child demon- general food aversion, 61% sensory
and based on Chatoor’s work in infant strates acute onset of food refusal. This food aversion, and 15% posttraumatic
psychiatry,5 children and adolescents typically presents after a traumatic feeding disorder, with 15% reporting 2
presenting with ARFID can be further event (eg, choking) or repeated trau- or more ARFID symptom types. Medi-
described by 1 of 4 subtypes (Table 1).6 matic insults to the oropharynx or gas- cal comorbidities were not assessed
Although these children usually have trointestinal tract (eg, intubation or up- in this sample.9 In a psychiatrically
one prominent presenting type, they per endoscopy). The child’s consistent based eating disorder program, ARFID
can meet criteria for more than one type refusal to eat can present in a variety prompting presentation to clinical care
based on their clinical history. The first of ways based on the child’s traumatic was 43% sensory food aversion, 22%
TABLE 1. TABLE 2.
hypothermia and bradycardia are sug- need for further evaluation and possibly 4. Kelly NR, Shank LM, Bakalar JL, Tanofsky-
Kraff M. Pediatric feeding and eating disor-
gestive of malnutrition processes, so af- referral for eating disorder treatment.21
ders: current state of diagnosis and treatment.
ter excluding medical causes, consider A more detailed screening tool for ado- Curr Psychiatry Rep. 2014;16(5):446-458.
a possible diagnosis of AN or ARFID. lescents with AN or BN would be the 26- doi: 10.1007/s11920-014-0446-z.
Laboratory evaluation may show leuko- item self-report Eating Attitudes Test or 5. Chatoor I. Diagnosis and Treatment of Feed-
ing Disorders in Infants, Toddlers and Young
penia, anemia, and/or thrombocytope- the modified Children’s Eating Attitude Children. Washington, DC: Zero to Three
nia, in addition to electrolyte changes Test, also a 26-item self-report measure Press; 2009.
(elevated blood urea nitrogen, hypomag- for children in third to eighth grade.22,23 6. Sacco B, Schwalen S. Treating avoidant re-
strictive food intake disorder in children and
nesemia, hypophosphatemia). These To screen for BED in children suffering adolescents. Paper presented at: Internation-
children may have sinus bradycardia from obesity, the Adolescent Binge Eat- al Association of Eating Disorders Profes-
or arrhythmias on electrocardiogram.19 ing Scale questionnaire can help identify sionals Symposium. March 2017; Las Vegas,
NV.
Young women who have demonstrated patients who may need eating-disorder
7. Fisher MM, Rosen DS, Ornstein RM,
oligomenorrhea or amenorrhea for 6 to specific treatment.24 There is no com- Mammel KA, et al. Characteristics of avoid-
12 months can show increased risk for monly used screening tool identifying ant/restrictive food intake disorder in chil-
or decreased bone mineral density for children at risk for ARFID, although dren and adolescents: a “new disorder” in
DSM-5. J Adolesc Health. 2014;55:49-52.
age.20 Children presenting with exces- the Behavioral Pediatrics Feeding As- doi:10.1016/j.jadohealth.2013.11.013.
sive weight gain should also be evalu- sessment Scale and the Child Food Neo- 8. Fisher M, Gonzalez M, Malizio J. Eating dis-
ated for BED after consideration of phobia Scale have successfully differ- orders in adolescents: how does the DSM-
5 change the diagnosis? Int J Adolesc Med
medical etiologies, and these children entiated a clinical ARFID sample from Health. 2015;27(4):437-441. doi:10.1515/
may demonstrate signs of metabolic children who are developing typically.25 ijamh-2014-0059.
syndrome.19 For children suspected of There are no screening tools specific for 9. Kurz S, van Dyck Z, Dremmel D, et al.
Early onset restrictive eating disturbances
having AN, the American Academy pica or rumination disorder.
in primary school boys and girls. Eur Child
of Pediatrics (AAP) has specific crite- Adolesc Psychiatry. 2015;24:779-785.
ria recommending medical admission CONCLUSION doi:10.1007/s00787-014-0622-z.
(Table 3).15 Eating disorders are prevalent in the 10. Norris ML, Robinson A, Obeid N, et al.
Exploring avoidant/restrictive food in-
When children have vomiting or pediatric population, so pediatricians are take disorder in eating disordered pa-
laxative abuse, metabolic changes are likely to encounter it in clinical practice. tients: a descriptive study. Int J Eat Disord.
evident on laboratory results. Addition- Familiarity with signs and symptoms 2014;47:495-499. doi:10.1002/eat.22217.
11. Norris ML, Katzman DK. Change is
ally, these children may present with of eating disorders will help pediatric never easy, but it is possible: reflections
erosion of dental enamel, dental carries, providers recognize children at risk for on avoidant/restrictive food intake disor-
and chipped teeth, in addition to parotid eating disorders, facilitating timely med- der two years after its introduction in the
DSM-5. J Adolesc Health. 2015;57:8-9.
gland enlargement or callouses on the ical evaluation and referral for eating-
doi:10.1016/j.jadohealth.2015.04.021.
dorsal aspect of the hands (from self- disorder treatment. 12. American Psychiatric Association. Diagnos-
induced vomiting).20 In these children, tic and Statistical Manual of Mental Disor-
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