SRI VENKATESHWARAA MEDICAL COLLEGE HOSPITAL AND RESEARCH

CENTRE
Ariyur, Puducherry. Ph.0413-2644435, 2644482
DEPARTMENT OF PATHOLOGY
Cell Injury OSPE Charts
(Competency: 2.8)

Chart A

A seven year old mentally retarded boy was bought to the paediatrics OPD, by the child care home person for
evening rise of temperature and complaints of swelling in the neck for past two months. On examination there
were multiple matted cervical lymph nodes of sizes ranging between 1 to 3cm. Biopsy of the lymph node showed
the below picture.

1. What is your diagnosis? Give justifications for your diagnosis.

2. What is the pathology seen in the stared area?
3. Write the morphological features of necrosis.
4. What are the different types of necrosis?
5. What is the composition of caseous necrosis?
6. What is a granuloma?
7. What is the pathogenesis of granuloma?
8. Enumerate causes of granuloma.
9. Enumerate causes of caseous necrosis
 SRI VENKATESHWARAA MEDICAL COLLEGE HOSPITAL AND RESEARCH
CENTRE
Ariyur, Puducherry. Ph.0413-2644435, 2644482
DEPARTMENT OF PATHOLOGY
Cell Injury OSPE Charts
(Competency: 2.8)

Chart B

A 45 yrs old male had severe chest pain and was admitted to the hospital. Investigations revealed elevated CK
MB and Troponin I & T. The microscopic picture of heart is given below.

Normal cardiac muscle

1. What is the probable diagnosis? What type of necrosis is seen in this condition?
2. What is the pathology seen in the stared area?
3. What are the other organs where this particular type of necrosis is seen?
4. What is the dye used to demonstrate this type of necrosis grossly. Explain how the dye works.
5. Write the morphological features of necrosis.
6. What are the different types of necrosis?
 SRI VENKATESHWARAA MEDICAL COLLEGE HOSPITAL AND RESEARCH
CENTRE
Ariyur, Puducherry. Ph.0413-2644435, 2644482
DEPARTMENT OF PATHOLOGY
Cell Injury OSPE Charts
(Competency: 2.8)

Chart C

A 52 year old male, chronic alcoholic came to the Casualty with pain in the abdomen which was radiating to
the back for the past 2 days. On examination, the patient had epigastric tenderness with guarding.
Serum amylase: More than three times the normal value
Serum lipase: Markedly elevated
Liver function test: Normal

The pancreas of the patient showed the below picture.

1. What is your diagnosis? Give justifications for your diagnosis.

2. What is the pathology seen in the stared area?
3. What are the other organs where this particular type of necrosis is seen?
4. Write the pathogenesis of this condition.
5. Write the morphological features of necrosis.
6. What are the different types of necrosis?
 SRI VENKATESHWARAA MEDICAL COLLEGE HOSPITAL AND RESEARCH
CENTRE
Ariyur, Puducherry. Ph.0413-2644435, 2644482
DEPARTMENT OF PATHOLOGY
Cell Injury OSPE Charts
(Competency: 2.8)

Chart D

A 24 year old female came to OPD with complaints of fatigue and malar rash on her face. The patient also had
oral ulcers. Bilateral shin shows palpable purpura.
Erythrocyte sedimentation rate: Elevated
C Reactive Protein: Elevated
Anti Nuclear Antibody: Positive.
ds DNA: Positive
Biopsy taken from the leg lesions showed the following picture

1. What is your diagnosis? Give justifications for your diagnosis.

2. What is the pathology seen in the stared area?
3. What is the pathogenesis of this finding?
 SRI VENKATESHWARAA MEDICAL COLLEGE HOSPITAL AND RESEARCH
CENTRE
Ariyur, Puducherry. Ph.0413-2644435, 2644482
DEPARTMENT OF PATHOLOGY
Cell Injury OSPE Charts
(Competency: 2.8)

4. Write the morphological features of necrosis.

5. What are the different types of necrosis?