Brand Name: Hepalean Generic Name: Heparin Drug Classification: Therapeutic: 

anticoagulants Pharmacologic: antithrombotics

Dosage, Route & Frequency Drug-Drug & Side Effects/

Drug Action Drug-Food Indications Contraindications Adverse Reactions
Recommended Prescribed Interactions (By System)

Adult: IV 5000-U NONE Potentiates Drug: May Prophylaxis and Contraindicated in GI: drug-induced
bolus dose, then the inhibitory prolong PT, treatment of patients with: hepatitis. Derm:
20,000–40,000 effect of which is used to various alopecia, rashes,
 Hypersensitivity
U infused over antithrombin monitor therapy thromboembolic urticaria. Hemat:
24 h, dose on factor Xa with oral  Uncontrolled Bleeding, anemia,
disorders including:
adjusted to and thrombin. anticoagulants; Bleeding thrombocytopenia
Venous
maintain desired In low doses, aspirin, NSAIDs
APTT or 5000– prevents the increase risk of
thromboembolism,  Severe Local: pain at
Pulmonary emboli, thrombocytopenia injection site.
10,000 U IV conversion of bleeding;
Atrial fibrillation
piggyback q4–6h prothrombin nitroglycerin IV  Open wounds MS: osteoporosis
with embolization,
SC 10,000– to thrombin by may decrease
20,000 U its effects on anticoagulant  Avoid use of Misc: fever,
Acute and chronic
followed by factor Xa. activity; products hypersensitivity.
consumptive
8000–20,000 U Higher doses protamine coagulopathies, containing benzyl
q8–12h neutralize antagonizes Peripheral arterial alcohol in
thrombin, effects of thromboembolism premature infants
Child: IV 50 U/kg
preventing the heparin.
bolus, then
conversion of
20,000 U/m2/24 Herbal:
fibrinogen to
h or 50–100 Feverfew,
fibrin.
U/kg q4h or 15– ginkgo, ginger,
25 U/kg/h valerian may
potentiate
bleeding.