Index

A Adenomatoid odontogenic tumor, 145-147, 146f

Abrasion of teeth, 367, 368f Adenosquamous carcinoma, 198
Abscess Adipose tissue neoplasms
palatal, 89, 89f description of, 316
periapical, 86-87, 87f lipoma, 316f, 316-317
pulpal, 80 liposarcoma, 317, 317f
Acantholysis, 266 Adult monostotic fibrous dysplasia, 101, 101f-102
Acanthosis, 177, 177f Afibrinogenemia, 421
Acanthosis nigricans, 174 Agranulocytosis, 400f, 400-401
Acetylsalicylic acid, 389, 390f Albumin, 421
Achlorhydria, 395 Alkaline phosphatase, 106
Acinar cells, 331, 331f Allergic reactions
Acinic cell carcinoma, 360-361, 361f-362f angioedema, 279, 279f
Acoustic neuromas, 306 contact stomatitis, 278f, 278-279
Acquired coagulopathy, 421 description of, 278
Acral lentiginous melanoma, 202 pathogenesis of, 278
Actinic cheilitis, 187, 187f Alveolar rhabdomyosarcoma, 315
Actinic lentigo, 173 Alveolar ridge, squamous cell carcinoma of, 192, 192f
Actinomyces, 238-240 Amalgam tattoo, 388f-389f, 388-389
Actinomycosis, oral-cervicofacial, 238-240, 239f Ameloblastic carcinoma, 159, 159f
Acute caries, 73 Ameloblastic fibroma, 155f-156f, 155-156
Acute lymphonodular pharyngitis, 221 Ameloblastic fibro-odontoma, 158-159
Acute nonspecific ulcers, 231, 231f Ameloblastoma
Acute osteomyelitis, 87-88, 88f acanthomatous pattern of, 139, 140f
Acute primary herpetic gingivostomatitis, 210f, 210-211 basal cell variant, 139, 140f
Acute pseudomembranous candidiasis, 241, 241f characteristics of, 136-137
Acute pulpitis, 80, 80f clinical features of, 137f, 137-138
Acyclovir, for herpes simplex virus, 213 common, 137f-140f, 137-141
Adenocarcinoma. See also Carcinoma definition of, 136
adenoid cystic carcinoma, 358f-360f, 358-360 desmoplastic, 139, 140f
definition of, 347 epithelial sources of, 136, 136f
not otherwise specified, 363-364 follicular pattern of, 138-139, 139f-140f
polymorphous low-grade, 362f-363f, 362-363 granular cell variant, 139, 140f
salivary gland, 356 histopathology of, 138-139, 139f
Adenoid cystic carcinoma, 358f-360f, 358-360 malignant, 159
Adenoid squamous cell carcinoma, 197-198 peripheral, 142-143, 143f
Adenoma plexiform pattern of, 139, 139f-140f
basal cell, 351, 351f radiographic features of, 138, 138f
canalicular, 351, 352f treatment of, 139, 141
cystadenomas, 355 types of, 137f
definition of, 347 unicystic, 141f-142f, 141-142
dermal analogue, 352 Amelogenesis imperfecta
inverted ductal papilloma, 355 clinical features of, 18
monomorphic, 351f, 351-352 definition of, 17
pleomorphic hypocalcified, 17-18, 19f
characteristics of, 348-349 hypomaturation, 18, 20f
clinical features of, 349f, 349-350 hypoplastic, 17-18, 19f
definition of, 348 radiographic features of, 18, 20
epidemiology of, 349-350 Witkop/Saul classification of, 18b
histopathology of, 350f, 350-351 Anemia
palatal, 349, 349f assessment of, 394, 394f
parotid gland, 349, 349f disease factors involved in, 394
plasmacytoid myoepithelial cells in, 350 fetal erythroblastosis, 398
treatment of, 351 hypochromic, 394

Page references followed by "f" indicate figures, "t" indicate tables,

and "b" indicate boxes.

433
434 INDEX

Anemia—cont’d Benign fibrous histiocytoma, 300f, 300-301

iron deficiency, 395 Benign lesions and tumors. See also specific lesion or tumor
microcytic, 394 acanthosis nigricans, 174
pathogenesis of, 394-395 actinic lentigo, 173
pernicious, 395-396, 396f cemento-ossifying fibroma, 116-117, 117f-118f
sickle cell, 396-397 central giant cell lesion, 120f-122f, 120-121
thalassemia, 397-398, 398f description of, 112-113
Aneurysmal bone cyst, 121-123, 122f exostosis, 113-114, 114f
Angiocentric lymphoma, 411 fibrous tissue
Angioedema, 279, 279f benign fibrous histiocytoma, 300f, 300-301
Angiosarcoma, 324, 324f benign solitary fibrous tumor, 301, 301f
Angular cheilitis, 243 description of, 298
Ankyloglossia, 28, 28f desmoplastic fibroma, 298
Ankylosis, 372, 373f fibromatosis, 298f-299f, 298-299
Anodontia myofibromatosis, 298, 299f
partial, 3-4 nodular fasciitis, 299-300, 300f
total, 3, 3f giant cell lesions, 117-123
Anticoagulant therapy, 421 Langerhans cell histiocytosis. See Langerhans cell histiocytosis
Antoni A tissue, 306-307 melanotic macules, 168f, 168-169
Antral mucoceles, 332 melasma, 173-174
Aphthous major, 255, 255f neural tissue
Aphthous minor, 253-255, 254f granular cell tumor. See Granular cell tumor
Apical periodontal cyst. See Periapical cyst neurilemoma, 306f, 306-307
Apical periodontitis, chronic, 83 neuroectodermal tumor of infancy, 312, 312f
Apoptosis, 186 neurofibroma, 307f-308f, 307-309
Arrested caries, 74 nevi. See Nevus
Arteriovenous malformations, 321 osteoblastoma, 115f-116f, 115-116
Aspergillosis, 248 osteoid osteoma, 115-116
Aspergillus, 248 osteoma, 114f-115f, 114-115
Atrophic (erythematous) candidiasis, 241-242, 242f peripheral giant cell granuloma, 119f-120f, 119-120
Attrition of teeth, 367, 367f Peutz-Jeghers syndrome, 173
Atypical lymphoproliferative disease, 412 salivary gland
Avulsion of teeth, 369 anatomic distribution of, 347t
characteristics of, 347t
intraductal papilloma, 355
B monomorphic adenoma, 351f, 351-352
“Baby-bottle” caries, 71, 73f oncocytoma, 354f, 354-355
Bacteria-associated leukocytosis, 403 papillary cystadenoma lymphomatosum, 353f, 353-354
Bacterial infections papillary cystadenomas, 355
Actinomyces, 238-240 pleomorphic adenoma. See Pleomorphic adenoma
impetigo, 235, 235f sialadenoma papilliferum, 355
Mycobacterium, 235-236 seborrheic keratosis, 173
oral-cervicofacial actinomycosis, 238-240, 239f smoker's melanosis, 165, 169, 169f, 176
osteomyelitis, 235 torus mandibularis, 113, 114f
pharyngitis, 234 torus palatinus, 113, 113f
scarlet fever, 234-235 traumatic bone cyst, 123f, 123-124
Staphylococcus, 235 Benign migratory glossitis, 375f-376f, 375-376
Streptococcus, 234-235 Benign solitary fibrous tumor, 301, 301f
tonsillitis, 234 Biliary atresia, 386
Treponema pallidum, 236-238 Biopsy
tuberculosis, 236 for herpes simplex virus diagnosis, 213
Bacterial sialadenitis, 343f, 343-344 for leukoplakia evaluations, 175
Band cells, 403 Birbeck granules, 126
Basal cell adenoma, 351, 351f Birthmarks. See Hemangioma
Basal cell carcinoma Blastomyces dermatitidis, 247-248
clinical features of, 198-199, 199f Blastomycosis, North American, 247-248
definition of, 198 Bleeding disorders
histopathology of, 199, 199f-200f capillary fragility, 419-420
treatment of, 199-200 causes of, 417b
Basaloid pattern, 359 coagulation disorders, 420-422
Basaloid squamous cell carcinoma, 198 description of, 417
Behcet syndrome, 256-257 hemostatic mechanisms, 417
Benign cystic lymph node. See Cervical lymphoepithelial cyst platelet disorders, 418-419
 INDEX 435

Blue nevus, 172, 172f Carcinoma—cont’d

Bone cyst acinic cell, 360-361, 361f-362f
aneurysmal, 121-123, 122f adenoid cystic, 358f-360f, 358-360
traumatic, 123f, 123-124 ameloblastic, 159, 159f
Bone disorders and disturbances basal cell
cleft lip, 33-36, 34f-35f clinical features of, 198-199, 199f
cleft palate, 33-36, 34f-35f definition of, 198
cleidocranial dysplasia, 37, 38f histopathology of, 199, 199f-200f
Crouzon syndrome, 38-39, 39f treatment of, 199-200
Down syndrome, 39-40, 40b, 40f metastases, 203-204
focal osteoporotic bone marrow defect, 36-37, 37f mucoepidermoid, 356f-357f, 356-358
hemangiomas, 321 nasopharyngeal, 195-197, 196f-197f
hemifacial atrophy, 33 odontogenic, 160, 160f
hemifacial hypertrophy, 32, 33f primary intraosseous, 160, 161f
lingual mandibular salivary gland depression, 36, 36f spindle cell, 195, 195f
oral-facial-digital syndrome, type I, 40 squamous cell. See Squamous cell carcinoma
Papillon-Lefèvre syndrome, 40-41, 41f TNM staging of, 194t
Treacher Collins syndrome, 39, 39f verrucous, 194f-195f, 194-195
BP-1 antigen, 263 Carcinoma in situ, 183, 184f
Branchial cleft cyst. See Cervical lymphoepithelial cyst Caries
Bruxism, 367 acute, 73
Buccal bifurcation cyst, 52 arrested, 74
Buccal mucosa, squamous cell carcinoma of, 192-193 “baby-bottle,” 71, 73f
Bulimia, 369f cemental, 72-73, 73f
Bullous pemphigoid, 263 chronic, 73
Burkitt lymphoma, 414-415, 415f definition of, 71
Burns dentin, 75f-76f, 75-76
acetylsalicylic acid, 389, 390f enamel, 74f, 74-75
chemical, 389-390, 390f-391f epidemiology of, 71
electrical, 381 pit and fissure, 71, 72f
thermal, 381, 381f preventive measures for, 71
pulpitis secondary to, 76
radiation, 383, 383f
C recurrent, 73
Calcifying epithelial odontogenic tumor, 143-145, 144f-145f root, 72-73, 73f
Calcifying odontogenic cyst, 147f-148f, 147-148 smooth-surface, 71, 72f-73f, 74
Canalicular adenoma, 351, 352f types of, 71-74, 72f-73f
Candida albicans infections Cavernous hemangioma, 320, 320f, 320-321
acute pseudomembranous candidiasis, 241, 241f Cellulitis, 88-89
angular cheilitis, 243 Cemental caries, 72-73, 73f
atrophic (erythematous) candidiasis, 241-242, 242f Cemental tear, 369
chronic hyperplastic candidiasis, 242f, 242-243 Cementoblastoma, 153-154, 154f
chronic mucocutaneous candidiasis, 244, 244f Cemento-osseous lesions
clinical features of, 240, 240b description of, 95-96
description of, 240 florid cemento-osseous dysplasia, 98, 99f
median rhomboid glossitis, 243f, 243-244 histopathology of, 96f
Candidiasis periapical cemental dysplasia, 95t, 96-98, 97f
acute pseudomembranous, 241, 241f Cemento-ossifying fibroma, 116-117, 117f-118f
atrophic (erythematous), 241-242, 242f Cementum disturbances, 27
chronic hyperplastic, 242f, 242-243 Central giant cell lesion, 120f-122f, 120-121
chronic mucocutaneous, 244, 244f Central neurofibroma, 308
classification of, 240b Central odontogenic fibroma, 151f, 151-152
human immunodeficiency virus, 230, 230f Cervical enamel projections, 14f, 14-15
predisposing factors, 240b Cervical lymphoepithelial cyst, 64, 65f
in Sjögren syndrome, 346 Chancre, 237, 237f
Cannon disease. See White sponge nevus Cheilitis glandularis, 280, 280f
Cap stage, of odontogenesis, 135, 135f Cheilitis granulomatosa, 281, 281f-282f
Capillary fragility, 419-420 Chemical burns, 389-390, 390f-391f
Capillary hemangioma, 321, 321f Chemical injuries
Capsid, 208, 208f amalgam tattoo, 388f-389f, 388-389
Carabelli cusp, 9 biliary atresia, 386
Carcinoma. See also Adenocarcinoma; Malignant neoplasms and congenital porphyria, 386
tumors cyclosporine, 387
436 INDEX

Chemical injuries—cont’d Connective tissue disorders—cont’d

erythroblastosis fetalis, 386 malignant neoplasms—cont’d
graphite, 389 types of, 288, 288b
nifedipine, 387-388, 388f vascular tissue, 324-325
phenytoin, 386-387 muscle tissue, 313-316
teeth, 385-386 neural tissue. See Neural tissue
tetracycline, 385, 385f odontogenic tumors
Cherubism, 95t, 103f-104f, 103-104 cementoblastoma, 153-154, 154f
Chicken pox. See Varicella-zoster virus odontogenic fibroma. See Odontogenic fibroma
Cholelithiasis, 337 odontogenic myxoma, 152f-153f, 152-153
Chondrosarcoma, 129-130, 130f Contact stomatitis, 278f, 278-279
Choristoma Cooley anemia. See Thalassemia
definition of, 325 Coumadin, 421
osseous and cartilaginous, 326-327 Coxsackieviruses
Chronic apical periodontitis, 83 acute lymphonodular pharyngitis, 221
Chronic caries, 73 definition of, 219
Chronic granulomatous disease hand, foot, and mouth disease, 220f, 220-221
characteristics of, 282 herpangina, 219-220, 220f
of childhood, 402 Craig cyst, 52
Chronic hyperplastic candidiasis, 242f, 242-243 Craniofacial dysostosis. See Crouzon syndrome
Chronic hyperplastic pulpitis, 82, 82f Craniofacial fibrous dysplasia, 99
Chronic leukemia, 405 CREST syndrome, 276
Chronic mucocutaneous candidiasis, 244, 244f Crohn disease, oral, 280-281
Chronic osteomyelitis, 90f-91f, 90-91 Crouzon syndrome, 38-39, 39f
Chronic pulpitis, 81, 81f Crown fractures, 368-369
Chronic sclerosing sialadenitis Cryptococcosis, 246-247
clinical features of, 340f, 340-341 Cryptococcosus neoformans, 246-247
definition of, 332, 340 Culture
histopathology of, 332f, 341 herpes simplex virus, 213
treatment of, 341 varicella-zoster virus, 216
Cicatricial pemphigoid, 263 Cutaneous T-cell lymphoma, 409
Civatte bodies, 261 Cyclic neutropenia, 401
Cleft lip, 33-36, 34f-35f Cyclins, 185
Cleft palate, 33-36, 34f-35f Cyclosporine, 387, 387f
Cleidocranial dysplasia, 37, 38f Cyst(s)
Coagulation disorders, 420-422 aneurysmal bone, 121-123, 122f
Coagulopathy, acquired, 421 calcifying odontogenic, 147f-148f, 147-148
Coccidioides immitis, 246 cervical lymphoepithelial, 64, 65f
Coccidioidomycosis, 246 definition of, 46
Cold sore. See Herpes labialis dentigerous, 49f-50f, 49-51
Coloration of teeth dermoid, 66-67, 67f
biliary atresia effects, 386 developmental. See Developmental cysts
erythroblastosis fetalis effects, 386 elements of, 46f
tetracycline effects, 385, 385f epidermoid, 67, 68f
Common ameloblastoma, 137f-140f, 137-141 eruption, 51f, 51-52
Complex odontoma, 157f fissural, 61
Compound nevus, 171, 172f gingival cyst of the adult, 59, 59f-60f
Compound odontoma, 157f glandular odontogenic, 60-61, 61f
Concrescence, 13f, 13-14 heterotopic oral gastrointestinal, 68
Condyloma acuminatum, 224-225, 225f incisive canal, 61
Congenital gingival granular cell tumor, 311, 311f lateral periodontal, 56-59, 58f
Congenital lip pits, 27f, 27-28 lymphoepithelial, 63-64, 64f-65f
Congenital porphyria, 386 mucus retention, 335-337, 336f-337f
Connective tissue disorders nasolabial, 63, 63f
adipose tissue, 316-317 nasopalatine duct, 62f, 62-63
age-based onset of, 288b oncocytic, 335
benign neoplasms paradental, 52f-53f, 52-53
fibrous tissue, 298-301 periapical, 47f-48f, 47-49, 84-86, 85f-86f
neural tissue, 306-312 residual, 48f, 49, 86
types of, 288, 288b thyroglossal tract, 65-66, 66f
fibrous tissue. See Fibrous tissue traumatic bone, 123f, 123-124
malignant neoplasms Cystadenomas, 355
fibrous tissue, 302f, 302-303 Cystic hygroma, 322-323, 323f
neural tissue, 313 Cytologic smear
 INDEX 437

Cytologic smear—cont’d Double lip, 28, 28f

herpes simplex virus, 213 Down syndrome, 39-40, 40b, 40f
varicella-zoster virus, 216 Downey cells, 404
Cytomegalovirus, 218f, 218-219 Drug-induced gingival hyperplasia
characteristics of, 297f, 297-298
cyclosporine, 387, 387f
D nifedipine, 387-388, 388f
Deciduous teeth phenytoin, 386-387
natal teeth, 5, 5f Dysgenic polycystic disease, 335, 336f
supernumerary, 4 Dysplasia
Delayed eruption of teeth, 5 adult monostotic fibrous, 101, 101f-102
Dens evaginatus, 9-10, 11f cleidocranial, 37, 38f
Dens invaginatus, 8-9, 9f-10f craniofacial fibrous, 99
Dental caries. See Caries dentin. See Dentin dysplasia
Dental lamina ectodermal, 3, 3f
cysts derived from epithelial, 180-183, 181f-182f
description of, 53 fibrous. See Fibrous dysplasia
gingival cyst of the adult, 59, 59f-60f florid cemento-osseous, 98, 99f
glandular odontogenic cyst, 60-61, 61f juvenile fibrous, 99-101, 100f
lateral periodontal cyst, 56-59, 58f Dystrophic calcifications, 81, 81f
in newborn, 59-60, 60f Dystrophic epidermolysis bullosa, 269, 269t
odontogenic keratocyst, 54f-55f, 54-56, 56b, 57f
definition of, 53
rests of, 53f E
Dentigerous cyst, 49f-50f, 49-51 Early bell stage, of odontogenesis, 135, 135f
Dentin Ectodermal dysplasia, 3, 3f
caries of, 75f-76f, 75-76 Ectomesenchymal chondromyxoid tumor, 326
secondary, 74 Electrical burns, 381
tertiary, 367 Embedded teeth, 6
Dentin dysplasia Embryonic skin cysts, 66-67, 67f
definition of, 23 Enamel
type I, 23-24, 24f acquired disturbances of, 15-17
type II, 24, 25f amelogenesis imperfecta
Dentinogenesis imperfecta clinical features of, 18
clinical features of, 20, 22f definition of, 17
definition of, 20 hypocalcified, 17-18, 19f
histopathology of, 21, 23, 23f hypomaturation, 18, 20f
radiographic features of, 21, 22f hypoplastic, 17-18, 19f
treatment of, 23 radiographic features of, 18, 20
types of, 20 Witkop/Saul classification of, 18b
Denture injuries and conditions caries of, 74f, 74-75
chemical, 390, 391f epithelium reductions, cysts derived from
papillomatosis, 380 dentigerous cyst, 49f-50f, 49-51
physical, 380, 380f eruption cyst, 51f, 51-52
sore mouth. See Atrophic (erythematous) candidiasis paradental cyst, 52f-53f, 52-53
Dermal analogue adenoma, 352 focal hypoplasia of, 15-16, 16f
Dermoid cyst, 66-67, 67f formation of, 17
Desmoglein 3, 266f generalized hypoplasia of, 16-17, 17f
Desmoplastic fibroma, 298 Encephalotrigeminal angiomatosis, 321
Developmental cysts Epidemic parotitis. See Mumps
description of, 61 Epidermoid cyst, 67, 68f
embryonic skin, 66-67, 67f Epidermolysis bullosa
lymphoepithelial cysts, 63-64, 64f-65f acquired, 268, 269t
mucosal epithelium, 68 clinical features of, 269-270, 270f
nasolabial cyst, 63, 63f definition of, 268
nasopalatine duct cyst, 62f, 62-63 hereditary, 268, 269t
thyroglossal tract cyst, 65-66, 66f histopathology of, 270, 270f
vestigial ducts, 62-63 treatment of, 270
vestigial tract, 65-66, 66f Epidermolysis bullosa acquisita, 268, 269t
Diffuse chronic sclerosing osteomyelitis, 91 Epidermolysis bullosa let lis, 269
Dilaceration, 7, 7f Epidermolysis bullosa simplex, 268, 269t
Dilantin. See Phenytoin Epimyoepithelial islands, 346, 346f
Dilated odontoma, 8, 9f Epithelial disorders
Discoid lupus erythematosus, 275f, 275-276 acanthosis, 177, 177f
438 INDEX

Epithelial disorders—cont’d Erythema multiforme—cont’d

acanthosis nigricans, 174 minor, 271f, 271-272
actinic lentigo, 173 oral lesions in, 272
anatomy of, 165, 176t pathogenesis of, 270-271, 271f
atrophy, 179-180 precipitating factors, 270, 271b
benign lesions, 165-167 toxic epidermal necrolysis, 271-273
characteristics of, 165-167 treatment of, 273-274
pigmented, 167-174 Erythroblastosis, fetal, 398
carcinoma in situ, 183, 184f Erythroblastosis fetalis, 386
dysplasia, 180-183, 181f-182f Erythroplakia, 183f, 183-184
erythroplakia, 183f, 183-184 Ewing sarcoma, 130-132, 131f
hyperkeratosis, 176f, 176-177 Exostosis, 113-114, 114f
hyperplasia, 176-179 External resorption of teeth, 370-372, 371f-372f
keratoacanthoma, 166-167, 167f
leukoplakia
clinical features of, 174f, 174-175, 175b F
proliferative verrucous, 178-179, 179f Factitious injuries, 378-379, 379f
malignant. See Squamous cell carcinoma Famciclovir, for herpes simplex virus, 213
melanoma. See Melanoma Fetal erythroblastosis, 398
melanotic macules, 168f, 168-169 Fibroma
melasma, 173-174 ameloblastic, 155f-156f, 155-156
nevus cemento-ossifying, 116-117, 117f-118f
blue, 172, 172f central odontogenic, 151f, 151-152
compound, 171, 172f desmoplastic, 298
definition of, 170 giant cell, 291
histologic types of, 170f irritation, 290
intramucosal, 170f-171f, 170-171 peripheral, 289, 291
junctional, 171, 171f peripheral odontogenic, 150f, 150-151
Spitz, 172-173 peripheral ossifying, 291f-292f, 291-292
nicotine stomatitis, 178, 178f psammomatoid juvenile ossifying, 116
odontogenic tumors Fibromatosis, 298f-299f, 298-299
adenomatoid, 145-147, 146f Fibro-osseous lesions
ameloblastoma. See Ameloblastoma cemento-osseous lesions. See Cemento-osseous lesions
calcifying epithelial, 143-145, 144f-145f characteristics of, 95t
calcifying odontogenic cyst, 147f-148f, 147-148 cherubism, 95t, 103f-104f, 103-104
squamous, 148-149, 149f description of, 95
oral submucous fibrosis, 179-180, 180f fibrous dysplasia. See Fibrous dysplasia
Peutz-Jeghers syndrome, 173 Fibrosarcoma, 302f-303f, 302-303
pigmentation considerations, 165 Fibrous dysplasia
pigmented lesions, 167-174 adult monostotic, 101, 101f-102
pseudoepitheliomatous hyperplasia, 177, 177f craniofacial, 99
seborrheic keratosis, 173 definition of, 99
smoker's melanosis, 165, 169, 169f, 176 features of, 95t
squamous cell carcinoma. See Squamous cell carcinoma juvenile, 99-101, 100f
squamous papilloma, 165-166, 166f polyostotic, 102f, 102-103
Epithelioid cell nevus. See Spitz nevus Fibrous tissue disorders
Epstein-Barr virus, 217-218 benign neoplasms
Epulis, 289, 318 benign fibrous histiocytoma, 300f, 300-301
Epulis fissuratum, 294, 380 benign solitary fibrous tumor, 301, 301f
Erosion of teeth, 368, 368f-369f description of, 298
Eruption cyst, 51f, 51-52 desmoplastic fibroma, 298
Eruption hematoma, 51-52 fibromatosis, 298f-299f, 298-299
Eruption of teeth myofibromatosis, 298, 299f
delayed, 5 nodular fasciitis, 299-300, 300f
disturbances in, 4-6 hyperplasia
impacted teeth, 5-6, 6f drug-induced gingival, 297f, 297-298
premature, 5, 5f focal fibrous, 290f, 290-291
Eruption sequestrum, 6f, 6-7 hereditary gingival fibromatosis, 296f, 296-297
Erythema multiforme hyperplastic gingivitis, 295-296, 296f
clinical features of, 271f-273f, 271-273 inflammatory fibrous, 294, 294f
definition of, 270 inflammatory papillary, 295, 295f
diagnosis of, 264t peripheral giant cell granuloma, 292-294, 293f
histopathology of, 273, 273f-274f peripheral ossifying fibroma, 291f-292f, 291-292
immunofluorescence testing of, 273, 274f malignant neoplasms, 302f, 302-303
major, 272, 273f Fingernail injuries, 378, 379f
 INDEX 439

Fissural cyst, 61 Gingivostomatitis, acute primary herpetic, 210f, 210-211

Fissured tongue, 377f, 377-378 Glandular odontogenic cyst, 60-61, 61f
Fistula Globulomaxillary radiolucency, 47
definition of, 88 Glossitis
oroantral, 89, 90f benign migratory, 375f-376f, 375-376
Floor of mouth, squamous cell carcinoma of, 191f, 191-192 Hunter, 395
Florid cemento-osseous dysplasia, 98, 99f median rhomboid, 243f, 243-244
Fluorescent antibody traumatic atrophic, 374f, 374-375
herpes simplex virus, 213 Graft-versus-host disease, 259, 406
varicella-zoster virus, 216 Granular cell tumor
Fluoride mottling, 17, 18f characteristics of, 309-311, 310f
Fluorosis, 17, 18f congenital gingival, 311, 311f
Focal chronic sclerosing osteomyelitis, 91 Granulocytic sarcoma, 406
Focal enamel hypoplasia, 15-16, 16f Granuloma
Focal epithelial hyperplasia, 226, 226f periapical, 81, 83-84, 84f
Focal fibrous hyperplasia, 290f, 290-291 peripheral giant cell, 119f-120f, 119-120, 292-294, 293f
Focal osteoporotic bone marrow defect, 36-37, 37f pyogenic, 318f, 318-319, 321-322
Foliate papillitis, 32 traumatic ulcerative granuloma with stromal eosinophilia, 378
Fordyce granules, 29f, 29-30 Graphite injuries, 389
Fractures of teeth Gummas, 238
crown, 368-369
root, 369, 369f
Frenal tag, 28, 28f H
Fusion, 12-13, 13f Hairy leukoplakia, 229f-230f, 229-230
Hairy tongue, 376f, 376-377
Hamartomas, 305-306, 306f
G Hand, foot, and mouth disease, 220f, 220-221
Gardner syndrome, 114, 115f, 326 Hand-Schüller disease, 124-125
Garrè osteomyelitis, 52, 91f, 91-92 Heck disease. See Focal epithelial hyperplasia
Gastrointestinal cyst, heterotopic oral, 68 Hemangioendothelioma, 324
Gemination, 12, 12f Hemangioma
Generalized enamel hypoplasia, 16-17, 17f bone, 321
Generalized macrodontia. See Macrodontia capillary, 321, 321f
Generalized microdontia. See Microdontia cavernous, 320f, 320-321
Genital wart. See Condyloma acuminatum characteristics of, 319-320
Geographic tongue. See Benign migratory glossitis clinical features of, 320, 320f
Ghost teeth. See Regional odontodysplasia definition of, 317, 319
Giant cell fibroma, 291 histopathology of, 321f, 321-322
Giant cell lesions intracranial, 321
aneurysmal bone cyst, 121-123, 122f intramuscular, 320, 320f
central, 120f-122f, 120-121 port-wine stain, 321, 321f
characteristics of, 117-118, 118b pyogenic granuloma vs., 321-322
histopathology of, 118f treatment of, 322
peripheral giant cell granuloma, 119f-120f, 119-120 Hemangiopericytoma, 324, 324f
Gilles de la Tourette syndrome, 379, 379f Hemidesmosome, 262
Gingiva Hemifacial atrophy, 33
chemical injuries of, 386 Hemifacial hypertrophy, 32, 33f
connective tissue, reactive hyperplasia of, 289, 289f Hemoglobin electrophoresis, 397f
cyclosporine effects, 387, 387f Hemophilia, 420-422
drug-induced hyperplasia of Hemostasis, 417
characteristics of, 297f, 297-298 Hereditary gingival fibromatosis, 296f, 296-297
cyclosporine, 387, 387f Hereditary hemorrhagic telangiectasia, 419-420, 420f
nifedipine, 387-388, 388f Hereditary opalescent dentin, 20, 22f
phenytoin, 386-387 Herniated buccal fat pad, 316
factitious injuries of, 378, 379f Herpangina, 219-220, 220f
hereditary fibromatosis of, 296f, 296-297 Herpes labialis, 211f, 212
hyperplasia of. See Gingiva, drug-induced hyperplasia of Herpes simplex virus
phenytoin effects, 386-387 acute primary herpetic gingivostomatitis, 210f, 210-211
physical injuries to, 373f, 373-374 acyclovir for, 213
squamous cell carcinoma of, 192, 192f clinical features of, 210
toothbrush trauma to, 373f, 373-374 diagnosis of, 213
Gingival cyst of the adult, 59, 59f-60f herpes labialis, 211f, 212
Gingivitis histopathology of, 213, 214f
human immunodeficiency virus, 231, 231f intraepithelial viral vesicle formation, 214f
hyperplastic, 295-296, 296f intraoral sites, 212
440 INDEX

Herpes simplex virus—cont’d Human papillomavirus—cont’d

latent infections, 209f condyloma acuminatum, 224-225, 225f
lytic infections, 209f Epstein-Barr virus and, 217
neonatal, 212 focal epithelial hyperplasia, 226, 226f
oral, 211f, 211-212 squamous papilloma, 223
prodromal stage, 213 structure of, 223
recurrent, 211-212 subtypes of, 223
structure of, 209-210 verruca vulgaris, 223-224, 224f
treatment of, 213 Human T-lymphotropic virus 1, 226
Herpes viruses Hunter glossitis, 395
latency of, 208-209 Hutchinson incisors, 16
types of, 209 Hutchinson triad, 238
Herpes zoster Hyaline bodies, 48, 48f
clinical features of, 215-216, 216f Hypercementosis, 14, 14f
treatment of, 217 Hyperkeratosis, 176f, 176-177
Herpetic whitlow, 212f, 212-213 Hyperorthokeratosis, 176, 176f
Herpetiform ulcers, 256, 256f Hyperparakeratosis, 176, 176f, 242
Hertwig root sheath, 136 Hyperparathyroidism, 109f, 109-110
Heterotopic oral gastrointestinal cyst, 68 Hyperplasia
Histiocytoma drug-induced gingival
benign fibrous, 300f, 300-301 characteristics of, 297f, 297-298
malignant fibrous, 302f-303f, 302-303 cyclosporine, 387, 387f
Histiocytosis X, 124 nifedipine, 387-388, 388f
Histoplasma capsulatum, 244-246, 245f phenytoin, 386-387
Histoplasmosis, 244-246, 245f epithelial
Hodgkin lymphoma acanthosis, 177, 177f
classification of, 406t hyperkeratosis, 176f, 176-177
clinical features of, 407 nicotine stomatitis, 178, 178f
definition of, 406 proliferative verrucous leukoplakia, 178-179, 179f
histopathology of, 407f-408f, 407-409 fibrous tissue
Reed-Sternberg cells, 406, 407f, 408 drug-induced gingival, 297f, 297-298
staging of, 406-407, 407t focal fibrous hyperplasia, 290f, 290-291
treatment of, 409 hereditary gingival fibromatosis, 296f, 296-297
Human herpesvirus-6, 219 hyperplastic gingivitis, 295-296, 296f
Human herpesvirus-7, 219 inflammatory fibrous hyperplasia, 294, 294f
Human herpesvirus-8, 219, 324 inflammatory papillary hyperplasia, 295, 295f
Human immunodeficiency virus peripheral giant cell granuloma, 292-294, 293f
acute nonspecific ulcers in, 231, 231f peripheral ossifying fibroma, 291f-292f, 291-292
AIDS stage of neural tissue
description of, 228-229, 229b palisaded encapsulated neuroma, 304-305, 305f
lesions in, 229b traumatic neuroma, 303-304, 304f
candidiasis in, 230, 230f vascular tissue, 318-319
CD4 cells, 227-228, 228f Hyperplastic gingivitis, 295-296, 296f
clinical features of, 228-229 Hyperplastic pulpitis, 82, 82f
fungal infections in, 231 Hypochromic anemia, 394
gingivitis in, 231, 231f Hypodontia, 3-4, 4f
hairy leukoplakia, 229f-230f, 229-230 Hypophosphatasia, 27
highly active antiretroviral therapy for, 228
Kaposi sarcoma, 232f-233f, 232-233, 324-325, 325f
lesions, 229b I
linear gingival erythema in, 231, 231f Idiopathic thrombocytopenic purpura, 418
non-Hodgkin lymphoma in, 233, 233f-234f, 410 Immune-mediated disorders
pediatric, 234 description of, 253
periodontitis in, 231, 231f epidermolysis bullosa
reverse transcriptase, 227 acquired, 268, 269t
RNA genome, 227 clinical features of, 269-270, 270f
stages of, 228-229 definition of, 268
structure of, 226-227, 227f hereditary, 268, 269t
symptomatic stage of, 228 histopathology of, 270, 270f
viral infections in, 234 treatment of, 270
Western blot technique for, 228 erythema multiforme
Human papillomavirus clinical features of, 271f-273f, 271-273
characteristics of, 186-187, 223 definition of, 270
 INDEX 441

Immune-mediated disorders—cont’d Immune-mediated reactions—cont’d

erythema multiforme—cont’d contact stomatitis, 278f, 278-279
diagnosis of, 264t orofacial granulomatosis
histopathology of, 273, 273f-274f cheilitis granulomatosa, 281, 281f-282f
immunofluorescence testing of, 273, 274f description of, 280
major, 272, 273f Melkersson-Rosenthal syndrome, 280, 282
minor, 271f, 271-272 oral Crohn disease, 280-281
oral lesions in, 272 pyostomatitis vegetans, 283
pathogenesis of, 270-271, 271f sarcoidosis, 282-283, 283f
precipitating factors, 270, 271b Wegener granulomatosis, 283
toxic epidermal necrolysis, 271-273 Impacted teeth, 5-6, 6f
treatment of, 273-274 Impetigo, 235, 235f
lichen planus Incisive canal cyst, 61
causative factors of, 257 Infections
clinical features of, 258-260 bacterial. See Bacterial infections
cutaneous, 259 Candida albicans. See Candida albicans infections
definition of, 257 caries. See Caries
diagnosis of, 260, 261f viral. See Viral infections
erosive, 258, 259f, 261, 264t Infectious mononucleosis, 217, 403-404
graft-versus-host disease in, 259 Inflammatory fibrous hyperplasia, 294, 294f
histopathology of, 260f, 260-261 Inflammatory papillary hyperplasia, 295, 295f
pathogenesis of, 257, 258f Internal resorption of teeth, 370, 370f
plaque, 258, 259f, 261 Intracranial hemangiomas, 321
reticular, 258, 258f Intraductal papilloma, 355
squamous cell carcinoma and, 257 Intramucosal nevus, 170f-171f, 170-171
treatment of, 261-262 Intramuscular hemangioma, 317, 320, 320f
variants of, 259 Intrinsic factor, 395
lichenoid reactions, 262, 262b, 262f Invagination stage, of odontogenesis, 135, 135f
lupus erythematosus Inverted ductal papilloma, 355
definition of, 274 Iron deficiency anemia, 395
discoid, 275f, 275-276 Irreversible pulpitis, 76-78, 78f
epidemiology of, 274 Irritation fibroma, 290
pathogenesis of, 274
subacute cutaneous, 275
systemic, 274-275, 275f J
lymphoepithelial sialadenitis, 344 Jaffe syndrome, 99
mucous membrane pemphigoid Jaw
clinical features of, 263-264, 264f metastases to, 203-204, 204f
definition of, 262 mucoepidermoid carcinoma of, 356-357
diagnosis of, 264, 264t Junctional epidermolysis bullosa, 268-269, 269t
epithelial atrophy in, 263 Junctional nevus, 171, 171f
histopathology of, 264-265, 265f Juvenile fibrous dysplasia, 99-101, 100f
oral, 263
pathogenesis of, 262-263, 263f
treatment of, 265 K
pemphigus vulgaris Kaposi sarcoma
clinical features of, 266-267, 267f clinical features of, 232f-233f, 232-233, 324, 325f
definition of, 265 definition of, 324
diagnosis of, 264t histopathology of, 232, 233f, 325, 325f
epidemiology of, 265 human herpesvirus-8 and, 219, 324
histopathology of, 267-268, 268f treatment of, 325
mucous membranes affected, 266 Keratin mucopolysaccharide dystrophy, 273, 273f
paraneoplastic, 266 Keratoacanthoma, 166-167, 167f
pathogenesis of, 266, 266f Keratocyst, odontogenic, 54f-55f, 54-56, 56b, 57f
treatment of, 268 Koebner phenomenon, 259
Tzanck cells, 267 Koplik spots, 222
progressive systemic sclerosis, 276-277, 277f
recurrent aphthous stomatitis. See Recurrent aphthous stomatitis
Immune-mediated reactions L
allergic reactions, 278f-279f, 278-279 Langerhans cell histiocytosis
angioedema, 279, 279f classification of, 125
cheilitis glandularis, 280, 280f clinical features of, 124f, 124-125
chronic granulomatous disease, 282 definition of, 124
442 INDEX

Langerhans cell histiocytosis—cont’d Lip(s)—cont’d

epidemiology of, 124 cheilitis granulomatosa, 281, 281f-282f
histopathology of, 126, 126f cleft, 33-36, 34f-35f
radiographic features of, 125f, 125-126 double, 28, 28f
treatment of, 126-127 herpes labialis, 211f, 212
Late bell stage, of odontogenesis, 135, 135f keratoacanthoma of, 167f
Latency, 208 melanotic macule, 168, 168f
Lateral periodontal cyst, 56-59, 58f mucocele of, 333f
Leiomyoma, 314f, 314-315 squamous cell carcinoma of, 189-191, 191f
Lentigo maligna melanoma, 201-202 Lip pits, congenital, 27f, 27-28
Leong premolar, 10 Lipoma, 316f, 316-317
Letterer-Siwe disease, 124-126 Liposarcoma, 317, 317f
Leukemia Ludwig angina, 89, 90
clinical features of, 405, 405f Lupus erythematosus
description of, 404-405 definition of, 274
histopathology of, 405-406 discoid, 275f, 275-276
laboratory findings, 405 epidemiology of, 274
leukocytosis vs., 402f pathogenesis of, 274
treatment of, 406 subacute cutaneous, 275
Leukocytes systemic, 274-275, 275f
disease of, 399 Lymphangioma, 317, 322-324, 323f
formation of, 398 Lymphatic drainage, 193f
neoplasms of, 404-405 Lymphoepithelial cysts, 63-64, 64f-65f
Leukocytosis Lymphoepithelial sialadenitis, 344
bacteria-associated, 403 Lymphoid cells, 404f
characteristics of, 399f Lymphoma
definition of, 402-403 angiocentric, 411
infectious mononucleosis, 403-404 Burkitt, 414-415, 415f
leukemia vs., 402f cutaneous T-cell, 409
mononuclear, 403 definition of, 404
virus-associated, 403 Hodgkin
Leukoedema, 30, 30f classification of, 406t
Leukopenia clinical features of, 407
agranulocytosis, 400f, 400-401 definition of, 406
cyclic neutropenia, 401 histopathology of, 407f-408f, 407-409
definition of, 399 Reed-Sternberg cells, 406, 407f, 408
description of, 400 staging of, 406-407, 407t
Leukoplakia treatment of, 309
clinical features of, 174f, 174-175, 175b mucosa-associated lymphoid tissue
proliferative verrucous, 178-179, 179f atypical lymphoproliferative disease, 412-413
Lichen planus characteristics of, 412
causative factors of, 257 clinical features of, 412-413
clinical features of, 258-260 definition of, 346, 412
cutaneous, 259 histopathology of, 413, 413f
definition of, 257 treatment of, 413
diagnosis of, 260, 261f non-Hodgkin
erosive, 258, 259f, 261, 264t classification of, 409b
graft-versus-host disease in, 259 clinical features of, 233, 233f-234f, 409-410, 410f
histopathology of, 260f, 260-261 definition of, 409
pathogenesis of, 257, 258f extranodal presentation of, 409-410
plaque, 258, 259f, 261 gene rearrangement assays, 412
reticular, 258, 258f histopathology of, 410-412, 411f
squamous cell carcinoma and, 257 in human immunodeficiency virus, 410
treatment of, 261-262 sites of, 409
variants of, 259 treatment of, 412
Lichenoid dysplasia, 183, 257
Lichenoid reactions, 262, 262b, 262f
Linear gingival erythema, 231, 231f M
Lingual mandibular salivary gland depression, 36, 36f Macrodontia, 2f, 2-3
Lingual thyroid nodule, 31f, 31-32 Macroglossia, 29, 29f
Lip(s) Malabsorption syndromes, 420
actinic cheilitis, 187, 187f Malignant fibrous histiocytoma, 302f-303f, 302-303
biting of, 378, 379f Malignant melanoma. See Melanoma
 INDEX 443

Malignant neoplasms and tumors. See also Adenocarcinoma; Microdontia, 2, 2f

Carcinoma; specific neoplasm or tumor Mitosoid cells, 226, 226f
ameloblastic fibro-odontoma, 158-159 Molar(s)
ameloblastoma. See Ameloblastoma impaction of, 4
fibrous tissue, 302f, 302-303 submerged deciduous, 372, 373f
leiomyoma, 314f, 314-315 Monoclonality, 411
leukemia. See Leukemia Monomorphic adenoma, 351f, 351-352
lymphoma. See Lymphoma Mononuclear leukocytosis, 403
melanoma. See Melanoma Mucocele
muscle tissue, 313-316 antral, 332
neural tissue, 313 characteristics of, 332-333
odontoma, 156-157, 157f-158f clinical features of, 333f, 333-334
salivary glands. See Salivary gland tumors, malignant color of, 334
sarcoma. See Sarcoma definition of, 332
squamous cell carcinoma. See Squamous cell carcinoma histopathology of, 334, 335f
types of, 288, 288b lower lip, 333f, 333-334
vascular tissue, 324f-325f, 324-325 marsupialization of, 334
Malignant polymorphous reticulosis, 410-411 mucous extravasation of, 332
Malignant solitary fibrous tumor, 302-303 plunging, 332
Mandibulofacial dysostosis. See Treacher Collins syndrome treatment of, 334-335
Maxilla, surgical ciliated cyst of, 68 Mucoepidermoid carcinoma, 356f-357f, 356-358
McCune-Albright syndrome, 99 Mucosa-associated lymphoid tissue lymphoma
Measles, 222 atypical lymphoproliferative disease, 412-413
Median rhomboid glossitis, 243f, 243-244 characteristics of, 412
Mediterranean anemia. See Thalassemia clinical features of, 412-413
Melanoacanthomas, oral, 168 definition of, 346, 412
Melanoma histopathology of, 413, 413f
acral lentiginous, 202 treatment of, 413
definition of, 200 Mucosal epithelium cysts, 68
epidemiology of, 200 Mucosal melanoma, 200
growth phases of, 200 Mucosal tissue
lentigo maligna, 201-202 amalgam injuries of, 388f-389f, 388-389
mucosal, 200 factitious injuries of, 378-379, 379f
nodular, 202-203, 203f graphite injuries of, 389
oral, 200 Mucositis, radiation, 382f, 382-383
skin, 200 Mucous membrane pemphigoid
superficial spreading, 200-201, 201f clinical features of, 263-264, 264f
Melanotic macules, 168f, 168-169 definition of, 262
Melasma, 173-174 diagnosis of, 264, 264t
Melkersson-Rosenthal syndrome, 280, 282, 377 epithelial atrophy in, 263
Metabolic bone diseases histopathology of, 264-265, 265f
description of, 105 oral, 263
hyperparathyroidism, 109f, 109-110 pathogenesis of, 262-263, 263f
osteogenesis imperfecta, 111-112, 112f treatment of, 265
osteopetrosis, 110-111, 111f Mucus cell metaplasia, 50
Paget disease Mucus retention cyst, 335-337, 336f-337f
bone turnover in, 106 Mulberry molars, 16
clinical features of, 106, 106f Multiple endocrine neoplasia syndrome, 305-306, 306f
complications of, 106 Multiple lipoblastomatosis, 316
definition of, 105 Multiple myeloma, 415-417
genetic predisposition for, 105 Multiple neurofibromatosis, 303, 307-309, 308f-309f
histopathology of, 107-108, 108f Mumps, 222. See also Viral endemic parotitis
osteosclerotic phase of, 107 Munro abscesses, 243
pathogenesis of, 105 Muscle tissue neoplasms
radiographic features of, 106-107, 107f description of, 313-314
scintigraphic findings, 107, 108f leiomyoma, 314f, 314-315
treatment of, 108-109 rhabdomyosarcoma, 315f, 315-316
Metastases Mycobacterium infections, 235-236
adenocarcinoma, 204f, 359 Mycoses
incidence of, 204t aspergillosis, 248
to jaw, 203-204, 204f Candida albicans. See Candida albicans infections
squamous cell carcinoma, 193, 194t coccidioidomycosis, 246
Microcytic anemia, 394 cryptococcosis, 246-247
444 INDEX

Mycoses—cont’d Nodular fasciitis, 299-300, 300f

histoplasmosis, 244-246, 245f Nodular melanoma, 202-203, 203f
North American blastomycosis, 247-248 Non-Hodgkin lymphoma
zygomycosis, 249, 249f classification of, 409b
Mycosis fungoides, 409 clinical features of, 233, 233f-234f, 409-410, 410f
Myelodysplastic syndrome, 400 definition of, 409
Myofibromatosis, 298, 299f extranodal presentation of, 409-410
Myositis ossificans, 327 gene rearrangement assays, 412
Myxoid neurofibroma, 309, 309f histopathology of, 410-412, 411f
in human immunodeficiency virus, 410
sites of, 409
N treatment of, 412
Nasolabial cyst, 63, 63f North American blastomycosis, 247-248
Nasopalatine duct cyst, 62f, 62-63
Nasopharyngeal carcinoma, 195-197, 196f-197f
Natal teeth, 5, 5f O
Necrotizing sialometaplasia, 341f-342f, 341-342 Odontoameloblastoma, 158
Necrotizing ulcerative periodontitis, 231, 231f Odontodysplasia, regional, 25f-26f, 25-27
Neonatal herpes simplex virus, 212 Odontogenesis, 135f-136f, 135-136
Neonatal teeth, 5 Odontogenic carcinoma, 160, 160f
Nerve sheath myxoma, 309 Odontogenic cysts
Neural tissue clinical features of, 47f
benign neoplasms of definition of, 46
granular cell tumor. See Granular cell tumor dentigerous cyst, 49f-50f, 49-51
neurilemoma, 306f, 306-307 eruption cyst, 51f, 51-52
neuroectodermal tumor of infancy, 312, 312f histogenetic classification of, 46b
neurofibroma, 307f-308f, 307-309 lateral periodontal cyst, 56-59, 58f
description of, 303 odontogenic keratocyst, 54f-55f, 54-56, 56b, 57f
hamartomas of, 305-306, 306f paradental cyst, 52f-53f, 52-53
hyperplasia disorders of periapical cyst, 47f-48f, 47-49
palisaded encapsulated neuroma, 304-305, 305f Odontogenic fibroma
traumatic neuroma, 303-304, 304f central, 151f, 151-152
malignant neoplasms, 313 definition of, 150
neurogenic sarcoma, 313, 313f peripheral, 150f, 150-151
Neurilemoma, 306f, 306-307 Odontogenic keratocyst, 54f-55f, 54-56, 56b, 57f
Neuroectodermal tumor of infancy, 312, 312f Odontogenic myxoma, 152f-153f, 152-153
Neurofibroma, 307f-308f, 307-309 Odontogenic tumors
Neurofibromatosis, multiple, 307-309, 308f-309f adenomatoid, 145-147, 146f
Neurogenic sarcoma, 313, 313f ameloblastic carcinoma, 159, 159f
Neuroma ameloblastic fibroma, 155f-156f, 155-156
acoustic, 306 ameloblastic fibro-odontoma, 158-159
palisaded encapsulated, 304-305, 305f ameloblastoma
traumatic, 303-304, 304f acanthomatous pattern of, 139, 140f
Neurothekeoma, 309 basal cell variant, 139, 140f
Neutropenia, cyclic, 401 characteristics of, 136-137
Neutrophil function disorders clinical features of, 137f, 137-138
chronic granulomatous disease of childhood, 402 common, 137f-140f, 137-141
description of, 401-402 definition of, 136
types of, 401-402 desmoplastic, 139, 140f
Neutrophilic leukocytosis, 402 epithelial sources of, 136, 136f
Nevoid basal cell carcinoma syndrome, 54-55, 55b, 56f follicular pattern of, 138-139, 139f-140f
Nevus granular cell variant, 139, 140f
blue, 172, 172f histopathology of, 138-139, 139f
compound, 171, 172f malignant, 159
definition of, 170 peripheral, 142-143, 143f
histologic types of, 170f plexiform pattern of, 139, 139f-140f
intramucosal, 170f-171f, 170-171 radiographic features of, 138, 138f
junctional, 171, 171f treatment of, 139, 141
Spitz, 172-173 types of, 137f
white sponge, 30-31, 31f unicystic, 141f-142f, 141-142
Newborn, dental lamina cyst of, 59-60, 60f calcifying epithelial, 143-145, 144f-145f
Nicotine stomatitis, 178, 178f calcifying odontogenic cyst, 147f-148f, 147-148
Nikolsky sign, 264, 267f fibroma. See Odontogenic fibroma
 INDEX 445

Odontogenic tumors—cont’d Paget disease—cont’d

mixed, 155-159
odontogenic carcinoma, 160, 160f
odontoma, 156-157, 157f-158f
primary intraosseous carcinoma, 160, 161f
squamous, 148-149, 149f
Odontoma
characteristics of, 156-157, 157f-158f
dilated, 8, 9f
Oncocytic cyst, 335
Oncocytoma, 354f, 354-355
Oncogenes, 185
Oncoproteins, 185
Oral Crohn disease, 280-281
Oral epithelial nevus. See White sponge nevus
Oral melanotic macule, 168, 168f
Oral submucous fibrosis, 179-180, 180f
Oral tonsil, 32, 32f
Oral-cervicofacial actinomycosis, 238-240, 239f
Oral-facial-digital syndrome, type I, 40
Oroantral fistula, 89, 90f
Orofacial granulomatosis
cheilitis granulomatosa, 281, 281f-282f
description of, 280
Melkersson-Rosenthal syndrome, 280, 282
oral Crohn disease, 280-281
Orthokeratin, 165, 176
Osseous and cartilaginous choristoma, 326-327
Osseous tissue disorders
description of, 325-326
developmental lesions, 326-327
myositis ossificans, 327
osseous and cartilaginous choristoma, 326-327
reactive lesions, 327
soft tissue osteoma, 326
Osteitis deformans. See Paget disease
Osteoblastoma, 115f-116f, 115-116
Osteogenesis imperfecta, 21f, 111-112, 112f
Osteogenic sarcoma, 127f-128f, 127-129
Osteoid osteoma, 115-116
Osteoma
clinical features of, 114f-115f, 114-115
description of, 325-326
soft tissue, 326
Osteomyelitis
acute, 87-88, 88f
chronic, 90f-91f, 90-91
definition of, 87
description of, 235
diffuse chronic sclerosing, 91, 91f
Garrè, 52, 91f, 91-92
Osteopetrosis, 110-111, 111f
Osteoporotic bone marrow defect, 36-37, 37f
Osteoradionecrosis, 383-384, 384f
Osteosclerosis, 90, 90f
P epidemiology of, 265
Paget disease
bone turnover in, 106
clinical features of, 106, 106f
complications of, 106
definition of, 105
genetic predisposition for, 105
histopathology of, 107-108, 108f
osteosclerotic phase of, 107
pathogenesis of, 105
radiographic features of, 106-107, 107f
scintigraphic findings, 107, 108f
treatment of, 108-109
Pain
assessment of, 79
pulpitis-related, 77-78, 78b
Palate
abscess of, 89, 89f
atypical lymphoproliferative disease of, 413
cleft, 33-36, 34f-35f
petechiae of, 418f
pleomorphic adenoma of, 349f
soft, 192, 192f
squamous cell carcinoma of, 192, 192f
Palisaded encapsulated neuroma, 304-305, 305f
Papillary cystadenoma, 355
Papillary cystadenoma lymphomatosum, 353f, 353-354
Papilloma, 165-166, 166f
Papillon-Lefèvre syndrome, 40-41, 41f
Paradental cyst, 52f-53f, 52-53
Parakeratin, 176, 176t
Paramyxoviruses, 221-222
Parotid gland
acinic cell carcinoma of, 361
anatomy of, 331
dysgenic polycystic disease of, 335, 336f
enlargement of, in Sjögren syndrome, 345, 345f
mucoepidermoid carcinoma of, 356
pleomorphic adenoma of, 349, 349f
sialolithiasis of, 338t
Parotitis
acute, 342
epidemic. See Mumps
viral endemic, 222, 342-343, 343f
Parulis, 88, 89f
Pautrier microabscess, 411
Pemphigoid
bullous, 263
cicatricial, 263
mucous membrane
clinical features of, 263-264, 264f
definition of, 262
diagnosis of, 264, 264t
epithelial atrophy in, 263
histopathology of, 264-265, 265f
oral, 263
pathogenesis of, 262-263, 263f
treatment of, 265
Pemphigus vulgaris
clinical features of, 266-267, 267f
definition of, 265
diagnosis of, 264t
histopathology of, 267-268, 268f
mucous membranes affected, 266
paraneoplastic, 266
pathogenesis of, 266, 266f
treatment of, 268
446 INDEX

Pemphigus vulgaris—cont’d Pleomorphic adenoma—cont’d

Tzanck cells, 267 palatal, 349, 349f
Periapical abscess, 86-87, 87f parotid gland, 349, 349f
Periapical cemental dysplasia, 95t, 96-98, 97f plasmacytoid myoepithelial cells in, 350
Periapical cyst, 47f-48f, 47-49 treatment of, 351
Periapical granuloma, 81, 83-84, 84f Pleomorphic rhabdomyosarcoma, 315
Periapical lesions Plexiform neurofibroma, 309
chronic apical periodontitis, 83 Plummer-Vinson syndrome, 395
cyst, 84-86, 85f-86f Plunging mucocele, 332
factors associated with, 83 Plunging ranula, 334
granuloma, 81, 83-84, 84f Polyclonality, 411
Periodontitis Polycythemia, 394
chronic apical, 83 Polymorphous low-grade adenocarcinoma, 362f-363f, 362-363
human immunodeficiency virus, 231, 231f Porphyria, congenital, 386
necrotizing ulcerative, 231, 231f Port-wine stain, 321, 321f
Peripheral ameloblastoma, 142-143, 143f Postherpetic neuralgia, 216-217
Peripheral fibroma, 289, 291 Pregnancy gingivitis, 295
Peripheral giant cell granuloma, 119f-120f, 119-120, 292-294, 293f Pregnancy tumors, 318
Peripheral odontogenic fibroma, 150f, 150-151 Primary intraosseous carcinoma, 160, 161f
Peripheral ossifying fibroma, 291f-292f, 291-292 Progressive systemic sclerosis, 276-277, 277f
Perlèche. See Angular cheilitis Proliferative verrucous leukoplakia, 178-179, 179f
Pernicious anemia, 395-396, 396f Psammomatoid juvenile ossifying fibroma, 116
Peutz-Jeghers syndrome, 173 Pseudoepitheliomatous hyperplasia, 177, 177f, 310
Pharyngitis Pseudosarcomatous fasciitis. See Nodular fasciitis
acute lymphonodular, 221 Puberty gingivitis, 295
bacterial, 234 Pulp polyp, 82
Phenytoin, 386-387 Pulp stones, 81, 81f
Philadelphia chromosome, 405 Pulpal abscess, 80
Physical injuries Pulpal calcifications, 24, 25f
abrasion, 367, 368f Pulpal fibrosis, 81
ankylosis, 372, 373f Pulpal necrosis, 78f, 78-79
attrition, 367, 367f Pulpitis
avulsion, 369 acute, 80, 80f
denture-related, 380, 380f caries and, 76
electrical burns, 381 causes of, 76-77, 77b
erosion, 368, 368f-369f chronic, 81, 81f
factitious, 378-379, 379f chronic hyperplastic, 82, 82f
fractures, 368-369, 369f definition of, 76
in Gilles de la Tourette syndrome, 379, 379f diagnostic techniques for, 79
radiation-induced, 381-385 electrical stimulation tests, 79
resorption histopathologic findings, 79-82
external, 370-372, 371f-372f hyperplastic, 82, 82f
internal, 370, 370f irreversible, 76-78, 78f
thermal burns, 381, 381f pain associated with, 77-78, 78b
tongue reversible, 76-77, 77f
benign migratory glossitis, 375f-376f, 375-376 Purified protein derivative, 236
fissured, 377f, 377-378 Pyogenic granuloma, 318f, 318-319, 321-322
hairy tongue, 376f, 376-377 Pyostomatitis vegetans, 283
traumatic atrophic glossitis, 374f, 374-375
toothbrush trauma, 373f, 373-374
toothpick injury, 374 R
Pit and fissure caries, 71, 72f Radiation injuries
Plasmacytoid myoepithelial cells, 350 caries, 383, 383f
Plasmacytoma, solitary, 415-417 cell damage in, 382
Platelet disorders mucositis, 382f, 382-383
thrombasthenia, 418-419 osteoradionecrosis, 383-384, 384f
thrombocytopenia, 418 overview of, 381-382
Pleomorphic adenoma sialadenitis secondary to, 340-341
characteristics of, 348-349 soft tissue, 384f, 384-385
clinical features of, 349f, 349-350 xerostomia, 383
definition of, 348 Radicular cyst. See Periapical cyst
epidemiology of, 349-350 Ranula, 333-334, 334f
histopathology of, 350f, 350-351 Reactive lesions, osseous tissue, 327
 INDEX 447

Reactive proliferations, 288 Salivary gland disorders—cont’d

Recurrent aphthous stomatitis mucocele—cont’d
aphthous major, 255, 255f antral, 332
aphthous minor, 253-255, 254f characteristics of, 332-333
Behcet syndrome, 256-257 clinical features of, 333f, 333-334
definition of, 253 color of, 334
epidemiology of, 253 definition of, 332
herpetiform ulcers, 256, 256f histopathology of, 334, 335f
systemic conditions associated with, 253 lower lip, 333f, 333-334
Recurrent caries, 73 marsupialization of, 334
Red blood cells mucous extravasation of, 332
anemia. See Anemia plunging, 332
description of, 394 treatment of, 334-335
Reed-Sternberg cell, 406, 407f, 408 mucus retention cyst, 335-337, 336f-337f
Regional odontodysplasia, 25f-26f, 25-27 necrotizing sialometaplasia, 341f-342f, 341-342
Rendu-Osler-Weber syndrome, 419-420, 420f parotitis
Residual cyst, 48f, 49, 86 acute, 342
Resorption of teeth viral endemic, 342-343, 343f
external, 370-372, 371f-372f sialadenitis. See Sialadenitis
internal, 370, 370f sialolithiasis
Rests of Malassez clinical features of, 338t, 338-339, 339f
definition of, 46 definition of, 337
periapical cyst originating from, 47f-48f, 47-49 histopathology of, 339f, 339-340
Rests of Serres incidence of, 338t
cysts derived from minor salivary gland, 338-339
description of, 53 pathogenesis of, 337, 338f
gingival cyst of the adult, 59, 59f-60f stone formation, 337, 338f
glandular odontogenic cyst, 60-61, 61f submandibular gland, 338t, 339f
lateral periodontal cyst, 56-59, 58f treatment of, 340
in newborn, 59-60, 60f Sjögren syndrome
odontogenic keratocyst, 54f-55f, 54-56, 56b, 57f benign lymphoepithelial lesion in, 346f
definition of, 46, 135 clinical features of, 344-345, 345f
Retrocuspid papilla, 32 definition of, 344
Retrovirus histopathology of, 345-346, 346f
description of, 208, 226 parotid gland enlargement in, 345, 345f
human immunodeficiency virus. See Human immunodeficiency primary, 344
virus secondary, 344-345
Reverse transcriptase, 227 sicca complex, 344
Reversible pulpitis, 76-77, 77f treatment of, 346
Rhabdomyoma, 313, 313f tumors. See Salivary gland tumors
Rhabdomyosarcoma, 315f, 315-316 Salivary gland tumors
Rhinocerebral zygomycosis, 249, 249f benign
Rhizomegaly, 3 anatomic distribution of, 347t
Romberg syndrome. See Hemifacial atrophy characteristics of, 347t
Root intraductal papilloma, 355
caries of, 72-73, 73f monomorphic adenoma, 351f, 351-352
fracture of, 369, 369f oncocytoma, 354f, 354-355
supernumerary, 10, 12, 12f papillary cystadenoma lymphomatosum, 353f, 353-354
Rubella, 221 papillary cystadenomas, 355
Rushton bodies, 86 pleomorphic adenoma. See Pleomorphic adenoma
sialadenoma papilliferum, 355
description of, 347
S growth patterns of, 348f
Salivary gland(s) malignant
acinar cells of, 331, 331f acinic cell carcinoma, 360-361, 361f-362f
anatomy of, 331f, 331-332 adenocarcinoma not otherwise specified, 363-364
lingual mandibular salivary gland depression, 36, 36f adenocarcinomas, 356
parotid gland. See Parotid gland adenoid cystic carcinoma, 358f-360f, 358-360
submandibular, 338t, 339f anatomic distribution of, 347t
Salivary gland disorders characteristics of, 347t
bacterial sialadenitis, 343f, 343-344 description of, 355-356
description of, 332 mucoepidermoid carcinoma, 356f-357f, 356-358
mucocele polymorphous low-grade adenocarcinoma, 362f-363f, 362-363
448 INDEX

Salivary gland tumors—cont’d Skin melanoma, 200

pathogenesis of, 347 Smoker's melanosis, 165, 169, 169f, 176
Sarcoidosis, 282-283, 283f Smooth-surface caries, 71, 72f-73f, 74
Sarcoma Soft palate, squamous cell carcinoma of, 192, 192f
angiosarcoma, 324, 324f Soft tissue disorders and injuries
chondrosarcoma, 129-130, 130f acetylsalicylic acid burn, 389, 390f
Ewing, 130-132, 131f ankyloglossia, 28, 28f
fibrosarcoma, 302f-303f, 302-303 congenital lip pits, 27f, 27-28
granulocytic, 406 double lip, 28, 28f
Kaposi Fordyce granules, 29f, 29-30
clinical features of, 232f-233f, 232-233, 324, 325f frenal tag, 28, 28f
definition of, 324 leukoedema, 30, 30f
histopathology of, 232, 233f, 325, 325f lingual thyroid nodule, 31f, 31-32
human herpesvirus-8 and, 219, 324 macroglossia, 29, 29f
treatment of, 325 oral tonsil, 32, 32f
liposarcoma, 317, 317f radiation-induced, 384-385
neurogenic, 313, 313f retrocuspid papilla, 32
osteogenic, 127f-128f, 127-129 white sponge nevus, 30-31, 31f
Paget disease and, 106 Soft tissue osteoma, 326
rhabdomyosarcoma, 315f, 315-316 Solitary plasmacytoma, 415-417
Scarlet fever, 234-235 Speckled erythroplakia, 183f, 183-184
Scurvy, 419 Spindle cell carcinoma, 195, 195f
Sebaceous tumors, 355 Spindle cell nevus. See Spitz nevus
Seborrheic keratosis, 173 Spitz nevus, 172-173
Secondary dentin, 74 Squamous cell carcinoma
Sequestrum, 88, 88f acquired immunodeficiency syndrome and, 187-188
Serology adenoid, 197-198
herpes simplex virus, 213 adenosquamous carcinoma, 198
varicella-zoster virus, 216-217 basaloid, 198
Sézary syndrome, 409 carcinogenetic mechanisms, 185f, 185-186
Shingles. See Herpes zoster causative factors
Sialadenitis actinic radiation, 187, 187f
bacterial, 343f, 343-344 alcohol consumption, 188
chronic sclerosing immunosuppression, 187
clinical features of, 340f, 340-341 infections, 187
definition of, 332, 340 lichen planus, 257
histopathology of, 332f, 341 nutritional deficiencies, 188
treatment of, 341 overview of, 184b
definition of, 340 preexisting oral diseases, 188
lymphoepithelial, 344 tobacco, 186-187
radiation therapy and, 340-341 clinical features of, 188
Sialadenoma papilliferum, 355 definition of, 184
Sialocysts, 335 dentigerous cyst and, 51f
Sialolithiasis epidemiology of, 184-185
clinical features of, 338t, 338-339, 339f histopathology of, 188-189, 189f
definition of, 337 incidence of, 190, 190t
histopathology of, 339f, 339-340 metastasis of, 193, 194t
incidence of, 338t moderately differentiated, 189, 189f
minor salivary gland, 338-339 nasopharyngeal carcinoma, 195-197, 196f-197f
pathogenesis of, 337, 338f poorly differentiated, 189, 190f
stone formation, 337, 338f sites of
submandibular gland, 338t, 339f alveolar ridge, 192, 192f
treatment of, 340 buccal mucosa, 192-193
Sickle cell anemia, 396-397 description of, 185
Sinus tract, 88, 89f floor of mouth, 191f, 191-192
Sjögren syndrome gingiva, 192, 192f
benign lymphoepithelial lesion in, 346f high-risk, 190, 190f
candidiasis in, 346 lower lip, 190-191, 191f
clinical features of, 344-345, 345f soft palate, 192, 192f
definition of, 344 tongue, 191, 191f
histopathology of, 345-346, 346f spindle cell carcinoma, 195, 195f
parotid gland enlargement in, 345, 345f verrucous carcinoma, 194f-195f, 194-195
primary, 344 well-differentiated, 188, 189f
secondary, 344-345 Squamous odontogenic tumor, 148-149, 149f
sicca complex, 344 Squamous papilloma, 165-166, 166f, 223
treatment of, 346 Staphylococcus infections, 235
 INDEX 449

Stevens-Johnson syndrome, 271-272 Teeth—cont’d

Stomatitis root—cont’d
contact, 278f, 278-279 fracture of, 369, 369f
nicotine, 178, 178f supernumerary, 10, 12, 12f
recurrent aphthous. See Recurrent aphthous stomatitis shape disturbances, 7-15
Stomatitis areata migrans, 375, 375f-376f size disturbances, 2-3
Strawberry tongue, 234 supernumerary, 4, 4f-5f
Strep throat, 234 supernumerary cusps, 9-10, 11f
Streptococcus infections, 234-235 supernumerary roots, 10, 12, 12f
Sturge-Weber syndrome, 321 taurodontism, 7-8, 8f
Subacute bacterial endocarditis, 235 tetracycline discoloration of, 385, 385f
Subacute cutaneous lupus erythematosus, 275 Tetracycline discoloration of teeth, 385, 385f
Submandibular gland, sialolithiasis of, 338t, 339f Thalassemia, 397-398, 398f
Submerged deciduous molar, 372, 373f Thermal burns, 381, 381f
Superficial spreading melanoma, 200-201, 201f Thrombasthenia, 418-419
Supernumerary cusps, 9-10, 11f Thrombocytopenia, 418, 418f
Supernumerary roots, 10, 12, 12f Thrush. See Acute pseudomembranous candidiasis
Supernumerary teeth, 4, 4f-5f Thyroglossal tract cyst, 65-66, 66f
Surgical ciliated cyst of maxilla, 68 Thyroid nodule, lingual, 31f, 31-32
Syphilis, 16-17, 237f-238f, 237-238 TNM system of staging, 193, 194t
Systemic lupus erythematosus, 274-275, 275f Tobacco
smoker's melanosis, 165, 169, 169f, 176
squamous cell carcinoma and, 186-187
T Togavirus, 221
Talon cusp, 10, 11f Tongue disorders
Taurodontism, 7-8, 8f ankyloglossia, 28, 28f
Teeth benign migratory glossitis of, 375f-376f, 375-376
abrasion of, 367, 368f chronic ulcers, 378, 378f
ankylosis of, 372, 373f fissured tongue, 377f, 377-378
assessment methods, 79 hairy tongue, 376f, 376-377
attrition of, 367, 367f macroglossia, 29, 29f
avulsion of, 369 median rhomboid glossitis, 243f, 243-244
biliary atresia effects, 386 physical injuries, 374-378
bulimia effects, 369f squamous cell carcinoma, 191, 191f
cemental tear of, 369 traumatic atrophic glossitis of, 374f, 374-375
cementum disturbances, 27 ulcers, 378, 378f
cervical enamel projections, 14f, 14-15 Tonsillitis, 234
chemical injuries of, 385-386 Toothbrush trauma, 373f, 373-374
coloration of Toothpick injury, 374
biliary atresia effects, 386 Torticollis, 298
erythroblastosis fetalis effects, 386 Torus mandibularis, 113, 114f
tetracycline effects, 385, 385f Torus palatinus, 113, 113f
concrescence of, 13f, 13-14 Toxic epidermal necrolysis, 271-273
congenital porphyria effects, 386 Traumatic atrophic glossitis, 374f, 374-375
dens invaginatus, 8-9, 9f-10f Traumatic bone cyst, 123f, 123-124
dentin disturbances, 20-24, 21f-25f Traumatic neuroma, 303-304, 304f
diagnostic techniques, 79 Traumatic ulcerative granuloma with stromal eosinophilia, 378
dilaceration of, 7, 7f Treacher Collins syndrome, 39, 39f
enamel structure disturbances, 15-20 Treponema pallidum, 236-237. See also Syphilis
erosion of, 368, 368f-369f Trisomy 21. See Down syndrome
eruption disturbances, 4-6 Tropism, 208
fracture of, 368-369, 369f Tuberculosis, 236
fusion of, 12-13, 13f Tumors
gemination of, 12, 12f benign. See Benign lesions and tumors
hypercementosis, 14, 14f benign solitary fibrous, 301, 301f
impacted, 5-6, 6f definition of, 288
natal, 5, 5f jaw metastases, 203-204, 204t
number-related disturbances, 3-4 malignant. See Malignant neoplasms and tumors
odontogenesis, 135f-136f, 135-136 malignant solitary fibrous, 302-303
physical injuries of, 367-372 metastases of, 203-204, 204t
regional odontodysplasia, 25f-26f, 25-27 odontogenic. See Odontogenic tumors
resorption of salivary gland. See Salivary gland tumors
external, 370-372, 371f-372f Tumor-suppressor proteins, 186
internal, 370, 370f Turner tooth, 15, 16f
root Tzanck cells, 267
caries of, 72-73, 73f
450 INDEX

U Viral infections—cont’d
Ulcers pathophysiology of, 208-209
aphthous, 253-255, 254f rubella, 221
herpetiform, 256, 256f varicella-zoster virus
tongue, 378, 378f clinical features of, 215, 215f
Unicystic ameloblastoma, 141f-142f, 141-142 definition of, 215
Urinary hydroxyproline, 106 herpes zoster, 215-216, 216f
histopathology of, 216-217
lesions in, 215, 215f
V treatment of, 217
Varicella-zoster virus Virus
clinical features of, 215, 215f coxsackieviruses, 219-221
definition of, 215 latency of, 208
herpes zoster, 215-216, 216f paramyxoviruses, 221-222
histopathology of, 216-217 replication of, 208, 208f
lesions in, 215, 215f retrovirus. See Retrovirus
treatment of, 217 structure of, 208f
Varix, 320, 320f togavirus, 221
Vascular leiomyomas, 314 Vitamin C deficiency, 419
Vascular tissue disorders von Recklinghausen disease, 303
angiosarcoma, 324, 324f
description of, 317-318
hemangioma. See Hemangioma W
hyperplasia, 318-319 Warthin tumor. See Papillary cystadenoma lymphomatosum
lymphangioma, 322-324, 323f Wegener granulomatosis, 283
pyogenic granuloma, 318f, 318-319 White blood cells
Venereal wart. See Condyloma acuminatum description of, 398-399
Verocay bodies, 307, 307f leukemia
Verruca vulgaris, 223-224, 224f characteristics of, 404-405
Verrucous carcinoma, 194f-195f, 194-195 clinical features of, 405, 405f
Verrucous hyperplasia, 178-179 description of, 404-405
Vestigial duct cysts, 62-63 histopathology of, 405-406
Vestigial tract cyst, 65-66, 66f laboratory findings, 405
Viral endemic parotitis, 222, 342-343, 343f leukocytosis vs., 402f
Viral infections treatment of, 406
acute lymphonodular pharyngitis, 221 leukocytes
condyloma acuminatum, 224-225, 225f disease of, 399
cytomegalovirus, 218f, 218-219 formation of, 398
Epstein-Barr virus, 217-218 leukocytosis
hand, foot, and mouth disease, 220f, 220-221 bacteria-associated, 403
herpangina, 219-220, 220f definition of, 402-403
herpes simplex virus infectious mononucleosis, 403-404
acute primary herpetic gingivostomatitis, 210f, 210-211 leukemia vs., 402f
acyclovir for, 213 mononuclear, 403
clinical features of, 210 virus-associated, 403
diagnosis of, 213 neutrophil function disorders
herpes labialis, 211f, 212 chronic granulomatous disease of childhood, 402
histopathology of, 213, 214f description of, 401-402
intraepithelial viral vesicle formation, 214f types of, 401-402
intraoral sites, 212 White sponge nevus, 30-31, 31f
latent infections, 209f Wickham's striae, 258, 258f
lytic infections, 209f
neonatal, 212
oral, 211f, 211-212 X
prodromal stage, 213 Xerostomia, 345, 346, 383
recurrent, 211-212
structure of, 209-210
treatment of, 213 Z
in human immunodeficiency virus, 234 Zygomycosis, 249, 249f
measles, 222 Zygomycota mucor, 249
mumps, 222 Zygomycota rhizopus, 249