CENTRAL UNIVERSITY OF TAMIL NADU

EXAMINATION FOR THE DEGREE OF

INTEGRATED MASTER OF SCIENCE
ACADEMIC SESSION 2016-17
END SEMESTER EXAMINATION

LIFE09: MEDICAL PARASITOLOGY

APRIL-MAY 2017 | TIME: 3 HOURS | TOTAL MARKS: 60 (SIXTY MARKS)

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INSTRUCTIONS TO CANDIDATES

1. This paper has TWO (2) parts:

Part A: One best answer (OBA) (10 questions)

Part B: Essay (7 questions)
State your matric number clearly on each answer script provided.

2. The candidates must answer any FIVE of the SEVEN questions in Part B.

3. Each question in Part A carries 1 (ONE) mark and Part B carries 10 (TEN)
marks.

4. While answering Part B questions, draw neatly labelled diagrams wherever

appropriate.

5. State the question number clearly on each answer script provided.

Registration No.: ………………………………………………………..

(This question paper consists of 17 questions in 4 printed pages)

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 PART A

1. Which of the following is the largest human intestinal nematode?

(A) Dracunculis medinensis

(B) Enterobius vermicularis
(C) Strongyloides stercoralis
(D) Ascaris lumbricoides

2. A 37-year-old female presents with rectal prolapse. The physician has found
characteristic barrel-shaped eggs with bipolar plugs in the patient’s stool. Which of
the following helminths is the likely cause of this manifestation?

(A) Echinococcus multilocularis

(B) Brugia malayi
(C) Fasciolopsis buski
(D) Trichiuris trichiura

3. Relapse in malaria is characterised by all of the following EXCEPT

(A) It is a feature of benign tertian malaria.

(B) It is characterised by the presence of some sporozoites at the resting phase.
(C) The initial tissue phase disappears completely in malarial relapse.
(D) Hepatocytes are the sites of multiplication of merozoites during relapse.

4. Helminthic infections is commonly characterized by predominance of which of the

following immune milieu in the host?

(A) Th1
(B) Th2
(C) Th9
(D) Th17

5. Which of the following parasites is transmitted by the use of improperly cleaned

contact lenses?

(A) Acanthamoeba castellani

(B) Naegleria fowleri
(C) Balamuthia mandrillaris
(D) Trichomonas tenax

6. Infected RBCs of Plasmodium vivax patients reveal which of the following

characteristics under microscopic examination?

(A) Maurer’s dots

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 (B) Ziemann’s stippling
(C) Schuffner’s dots
(D) Negri bodies

7. All the following features confer resistance to malaria EXCEPT

(A) Duffy blood antigens

(B) HLA-Bw53
(C) Glucose-6-phosphate dehydrogenase
(D) Pregnancy

8. Which of the following feature is pathognomonic of Chagas disease?

(A) Winterbottom’s sign

(B) Meyer’s-Kouwenaar syndrome
(C) Romana’s sign
(D) Loeffler’s syndrome

9. Tropical pulmonary eosinophilia is a common clinical manifestation associated

with which of the following helminthic infections?

(A) Paragonimus westermani

(B) Ascaris lumbricoides
(C) Wuchereria bancrofti
(D) Taenia saginata

10. Prolonged infestation with Ascaris lumbricoides leads to the deficiency of which
of the following vitamins in the host?

(A) Vitamin A
(B) Vitamin B2
(C) Vitamin C
(D) Vitamin K

PART B

1. Describe the morphology, life cycle and clinicopathogenesis of Leishmania

donovani. Elucidate on the laboratory diagnosis of visceral leishmaniasis.

2. Describe the morphology and life cycle of Taenia saginata. Add a note on the
pathogenesis and laboratory diagnosis of human cysticercosis.

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3. Name any three aerobic amoebae. Describe the etiology, morphologic features,
life
cycle, pathogenesis and clinical features of the causative agent of granulomatous
amoebic encephalitis (GAE). Add a note on the laboratory diagnosis of GAE.

4. Describe the morphology of Echinococcus granulosus. Discuss on the life

cycle, pathogenesis and laboratory diagnosis of human hydatidosis.

5. Describe the life cycle, pathogenesis and clinical features of falciparum malaria.
Elucidate on the prophylaxis, prevention and control of human malaria.

6. Write short notes on any FOUR of the following:

a) Venereal trichomoniasis b) Vector-borne parasitic zoonoses

c) Transfusion malaria d) Antigenic polymorphism in trypanosomes
e) Tropical pulmonary eosinophilia f) Eggs of human ascarids

7. Describe the morphological features of Wuchereria bancrofti microfilariae. Explain

the life cycle, pathogenesis and clinical features of bancroftian filariasis.

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