INTERNATIONAL Senate endorsement ref.

:
ISLAMIC UNIVERSITY Senate endorsement date:
MALAYSIA Version no:
Version effective date:

COURSE OUTLINE
1. Course Title: Pharmacology of the Peripheral Nervous System

2. Course Code: PHM 2113

3. Credit Value: 3

4. MQF Level: 6

5. Affected Batch: 14th batch onward

6. Centre of Studies: Pharmacy

7. Department/Unit: Basic Medical Sciences

8. Course Synopsis:

The course consists of a series of lectures, tutorials, laboratory practical sessions, group
discussions on case studies and quizzes. This course provides understanding on the
general anatomy, the organizational structures, synthesis of the neurotransmitter
involved, function of peripheral nervous system and drugs that affect the peripheral
nervous system, their clinical uses and side effects.

9. Course Classification within the Curriculum: Core course

10. Prerequisite(s) (if any):

11. Course Learning Outcomes

Bloom’s Programme
Taxonomy Soft skills
No. Outcomes Outcomes
(KI)
C A P (PO)
1 Apply the anatomical, 3 LL1 1
biochemical, physiological and
pharmacological knowledge to the
clinical diseases of peripheral
nervous system and their
treatment.
 2 Describe the effects of A3 1
sympathetic and parasympathetic
nervous system and advice the
choice of drugs for treatment.
3 Interpret and report the practical C3 P2 TS3, LS1 5
and case studies in groups
regarding effects of drugs on
peripheral nervous system.
4 Recognize various drugs affecting CTPS3, 5
peripheral nervous system and LL1
their adverse effects and find the
alternative solution in different
situations.
5 Analyze disease processes C6 1
associated with autonomic
nervous system dysfunctions.

Additional Mapping for Professional Programmes (e.g. Engineering)

Outcomes Complex Problem Complex Analysis Knowledge Profile

12. LO - Instruction Method - Assessment Alignment:

Outcomes Teaching-Learning Methods Assessment Methods
LO1 Lecture and tutorial Continuous assessment
and final exam
LO2 Lecture and tutorial Continuous assessment
and final exam
LO3 Lecture, tutorial Continuous assessment,
final exam
LO4 Lecture, tutorial Continuous assessment,
final exam
LO5 Lecture, tutorial

13. Assessment Methods Weightage:

Methods Percentage
Continuous assessment
Quiz (2 quizzes) 20
Assignment/Poster Presentation 15
Practical report/assessment 15
End semester exam
MCQ (15 questions) 15
Short essay (3 out of 4 questions) 15
 Long essay (2 out of 3 questions) 20
TOTAL 100

14. Student Learning Time:

1. Instruction Component Total Allocated Hours
1.1. Teacher-oriented methods
Lecture 23
Tutorial 6
Practical 6
Case Study 1
Poster Presentation 2
Quiz (2 quizzes: 30 minutes/quiz) 1
1.2. Student-oriented methods
0
Total Instructor Contact Hours: 38.5
2. Independent Learning Component Total Estimated Hours
2.1. Reading and revision
Self-reading 35
2.2. Estimated hours for preparation toward assessments
Quizzes 6
Practical 4
3. Assessment Outside Instruction Hours Total Allocated Hours
Final Exam 19.25
TOTAL SLT (104.25/40= 2.61) 3

15. Course Contents and Related SLT:

Face to Face Self-Learning
Week Topics
Hours Hours
Introduction to the peripheral nervous system
(Dr Abdul Razak)
Organisation and neurotransmitters of the
1 peripheral nervous system I (Dr Che Anuar) 3 3
Organisation and neurotransmitters of the
peripheral nervous system II (Dr Che Anuar)
 Cholinergic / Cholinomimetic agents (Dr Abdul
Razak)
2 Anticholinesterases (Dr Abdul Razak) 3 3

The ganglion blockers (Dr Abdul Razak)

Antimuscarinic agents (Dr Rusdi)

Tutorial I (Dr Abdul Razak)
3 3 3
Neuromuscular blocking agents (Dr Rusdi)

Tutorial II (Dr Che Anuar)

Medicinal Chemistry of the cholinergic system I

4 (Dr Qamar) 3 3

Medicinal Chemistry of the cholinergic system II

(Dr Qamar)

Medicinal Chemistry of the cholinergic system

III (Dr Qamar)

5 Sympathomimetic agents I (Dr Abdul Razak) 3 3

Sympathomimetic agents II (Dr Abdul Razak)

6 Practical I: Neuromuscular blockade (Dr Rusdi) 3 2

Sympathomimetic agents III (Dr Abdul Razak)

Alpha agonist (Dr Wan Azizi)

7 3 3
Alpha blocker (Dr Wan Azizi)
 Medicinal Chemistry of the adrenergic system I
(Dr Qamar)

Medicinal Chemistry of the adrenergic system II

8 3 3
(Dr Qamar)

Tutorial III (Dr Qamar)

Beta agonist (Dr Wan Azizi)

Beta blockers I (Dr Wan Azizi)

9 3 3
Beta blockers II (Dr Wan Azizi)

Practical II: Sympathetic & parasympathetic

10 3 2
nervous system. (Dr Rusdi)
Tutorial IV (Dr Abdul Razak)

Tutorial V (Dr Wan Azizi)

11 3 3
Imidazoline system & Imidazoline agonists (Dr
Abdul Razak)

Case study (Dr Abdul Razak)

PT: Introduction to pharmacotherapeutics of

PNS disorder I (Dr Haniki)
12 3 3
PT: Introduction to pharmacotherapeutics of
PNS disorder II (Dr Haniki)

13 Tutorial VI (Dr Haniki) 1 1

16. References:

16.1. Required

1. Harvey, R.A. (2012) Lippincott's Illustrated Reviews: Pharmacology, (5th Ed.)

2. Patrick, G. L. (2005) An Introduction to Medicinal Chemistry (3rd ed.). Oxford.

3. Tortora, G.J. (2005). Principles of Human Anatomy (10th ed.).  New York: John
Wiley & Sons.

16.2. Recommended
 1. Bennett, P. N., Brown, M. J. (2008) Clinical Pharmacology (10th ed.) Churchill
Livingstone Elsevier.
2. Goodman, A., & Gilman. (2007) Goodman & Gilman’s The Pharmacological
Basis of Therapeutics (11th ed.). New York, Mc Graw-Hill.
3. Katzung, B.G. (2012) Basic & Clinical Pharmacology. (12th ed.). New York:
Prentice- Hall Inc.
4. Rang, H. P., Dale, M. M., Ritter, J. M., Flower, R. J. (2007) Rang and Dale’s
Pharmacology (6th ed.) Churchill Livingstone Elsevier.
5. Stringer, J.L. (2001). Basic concepts in Pharmacology (2nd ed.). New York:
McGraw-Hill Companies.

Prepared by: Checked by: Approved by:

Signature: Signature: Signature:

Assoc Prof Dr Abdul Razak Asst. Prof. Dr Nurul Asyiqin Asst. Prof. Dr Siti Hadijah
Kasmuri Yusof Shamsuddin
Course Coordinator, Head, Department of Basic Dean, Kulliyyah of Pharmacy.
Department: Basic Medical Medical Sciences.
Sciences. Date:
Date: Date:
 ANNEX

I. Course Instructor Details

Semester: Academic Year:

No. Name Email Department

1. Asst. Prof. Dr. Muhamad rusdirusmili@iium.edu.m Basic Medical Sciences
Rusdi Ahmad Rusmili y
2. Asst. Prof. Dr. Wan Azizi drwanazizi@iium.edu.my Basic Medical Sciences
Wan Sulaiman
3. Asst. Prof. Dr. Che Anuar dranuar@iium.edu.my Basic Medical Sciences
Che Mohamad
4. Assoc. Prof. Dr. Qamar quahmed@iium.edu.my Pharmaceutical Chemistry
Ahmed
5. Assoc Prof Dr Mohamad haniki@iium.edu.my Pharmacy Practices
Haniki Nik Mohamed
6. Assoc. Prof Dr Abdul drazak@iium.edu.my Basic Medical Sciences
Razak Kasmuri

II. Programme Learning Outcomes

At the end of the programme, students are expected to be able to:

No. Outcomes Outcome Domain

1 Demonstrate familiarity in all aspects of drugs beginning with Knowledge
their origin (synthetic or natural products), medicinal
chemistry, pharmacology, compounding or manufacturing and
their usage.
2 Use relevant skills learnt as part of professional and personal Practical Skills
growth for future pharmacists’ roles and research in various
settings.
3 Implement the concept of pharmaceutical care in a socially Social Skills and
responsible manner for the progress of the nation and the Responsibilities
Ummah.
4 Demonstrate commitment to ethics, autonomy and Values, Attitudes and
professionalism in pharmacy. Professionalism
5 Apply effective communication skills in the delivery of Communication,
pharmaceutical care, perform patient counselling and Leadership and Team
monitoring and show leadership qualities in working as a team. Skills
6 Analyse the common signs and symptoms, laboratory findings Problem Solving and
and drugs in the identification and resolution of drug related Scientific Skills
problem and management of common disorders involving
various body systems.
7 Use the necessary learning skills in information management Information
and apply effective strategies for lifelong self-improvement. Management and
Lifelong Learning Skills
8 Apply basic managerial and entrepreneurial skills for Managerial and
pharmacists in compounding or manufacturing, business, Entrepreneurial Skills
administration and management.
9 Apply Islamic principles as part of professional ethics for Islamicisation
pharmacists and analyse scientific issues from the Islamic
perspective.