Direct-acting cholinergic agonists like bethanechol, carbachol, cevimeline, and pilocarpine bind to and activate cholinergic receptors, mainly muscarinic receptors. They are used to treat non-obstructive urinary retention, neurogenic bladder atony, esophageal reflux, symptoms of dry mouth, and induction of miosis to relieve increased intraocular pressure of glaucoma. Potential adverse effects include cardiovascular issues like bradycardia and hypotension, as well as gastrointestinal, urinary, and central nervous system effects. Contraindications include conditions like bradycardia, hypotension, peptic ulcer, and intestinal or recent gastrointestinal obstruction or surgery.
Direct-acting cholinergic agonists like bethanechol, carbachol, cevimeline, and pilocarpine bind to and activate cholinergic receptors, mainly muscarinic receptors. They are used to treat non-obstructive urinary retention, neurogenic bladder atony, esophageal reflux, symptoms of dry mouth, and induction of miosis to relieve increased intraocular pressure of glaucoma. Potential adverse effects include cardiovascular issues like bradycardia and hypotension, as well as gastrointestinal, urinary, and central nervous system effects. Contraindications include conditions like bradycardia, hypotension, peptic ulcer, and intestinal or recent gastrointestinal obstruction or surgery.
Direct-acting cholinergic agonists like bethanechol, carbachol, cevimeline, and pilocarpine bind to and activate cholinergic receptors, mainly muscarinic receptors. They are used to treat non-obstructive urinary retention, neurogenic bladder atony, esophageal reflux, symptoms of dry mouth, and induction of miosis to relieve increased intraocular pressure of glaucoma. Potential adverse effects include cardiovascular issues like bradycardia and hypotension, as well as gastrointestinal, urinary, and central nervous system effects. Contraindications include conditions like bradycardia, hypotension, peptic ulcer, and intestinal or recent gastrointestinal obstruction or surgery.
Direct-acting cholinergic agonists like bethanechol, carbachol, cevimeline, and pilocarpine bind to and activate cholinergic receptors, mainly muscarinic receptors. They are used to treat non-obstructive urinary retention, neurogenic bladder atony, esophageal reflux, symptoms of dry mouth, and induction of miosis to relieve increased intraocular pressure of glaucoma. Potential adverse effects include cardiovascular issues like bradycardia and hypotension, as well as gastrointestinal, urinary, and central nervous system effects. Contraindications include conditions like bradycardia, hypotension, peptic ulcer, and intestinal or recent gastrointestinal obstruction or surgery.
and cautions : Bradycardia, Adverse effects: Cardiovascular Bethanechol bladder atony in adults and hypotension, peptic ulcer, intestinal effects can include bradycardia, heart children, treatment of obstruction, or recent GI surgery. block, hypotension, and even cardiac esophageal reflux arrest. GI effects can include nausea, vomiting, cramps, diarrhea, Induction of miosis to relieve They bind to and increased salivation, and involuntary Carbachol increased intraocular irect-acting D activate the cholinergic pressure of glaucoma Route: Oral and defecation related to the increase in GI secretions and receptors (usually eye drops cholinergic agonists Treatment of symptoms of activity. Urinary tract effects can muscarinic receptors) Cevimeline include a sense of urgency related to dry mouth cholinergic N &M stimulation of the bladder muscles and sphincter relaxation. Miosis and blurred Induction of miosis to relieve vision, headaches, dizziness, and increased intraocular drowsiness can occur related to CNS Pilocarpine pressure of glaucoma, cholinergic effects. treatment of symptoms of dry mouth