FINALS

PHARMACEUTICAL INORGANIC CHEMISTRY

114L

UNIT 3, CHAPTER 5: DENTAL PRODUCTS

• Dental fluorosis is caused by taking too much
SCOPE fluoride over a long period when the teeth are
A. Anticariogenic Agents forming under the gums.
B. Polishing Agents • Relatively resistant to dental carries
C. Desensitizing Agents • Cosmetic concern
DENTAL PRODUCTS
- Teeth are accessory digestive organ
- Teeth are used to bite and chew food, the first step
in food digestion
A. ANTICARIOGENIC AGENTS
DENTAL CARRIES
or tooth decay, involves demineralization (softening) of the
tooth enamel. If untreated, microorganisms may invade the
pulp, causing inflammation and infection, which subsequent
death of pulp and abscess of the alveolar bone.

POLISHING AGENTS DESENTISIZING AGENTS

- Dentifrices that are - Reduce pain in sensitive

ABRASIVE in nature. caused by cold, heat our
- Responsible for physically touch
removing plaque and debris - These products are non-
FORMATION OF CAVITIES on tooth abrasive and are not used
INORGANIC in a regular basis unless
• Growth and implementation of cariogenic
PHARMACEUTICAL directed by a dentist
microorganisms (Streptococcus mutans). Bacteria
produce lactic acid (demineralize the enamel). COMPOUNDS: INORGANIC
• Dicalcium PHARMACEUTICAL
• The demineralized enamel initially appears as white,
phosphate COMPOUNDS:
chalky area and eventually becomes brown or
• Sodium • Zinc Chloride
yellow.
• Diet is also a factor in the development of dental metaphosphate • Strontium
caries. • Calcium Chloride
• Bacterial plaque facilitates tooth decay process by pyrophosphate
forming packets ore crevices on the tooth surface in • Calcium
which the food particles can stick and be decayed by carbonate
bacteria. • Calcium
• If plaque is nor removed, it calcifies into CALCULUS. nonhydrogen
phosphate
PREVENTION OF DENTAL CARIES
• Pumice (too
Oral and Dental Hygiene with the use of DENTIRFICES abrasive to be
• Dentifrices are products that enhance the removal of used daily in a
stain and dental plaque by the toothbrush dentifrice)
• The most accepted approach to prevent dental
caries includes flossing and tooth brushing
accompanies by using anticariogenic agents.
• Anticariogenic agents are substances which
prevents tooth decay
FLUORIDE
- Replaces the hydroxyl anion in hydroxyapatite,
forming fluorapatite (outer surface if tooth enamel).
Fluorapatite hardens the enamel and makes it more
acid resistant.
INORGANIC PHARMACEUTICAL COMPOUNDS:
• Sodium Fluoride (NaF)
• Stannous Fluoride (SnF2)
DENTAL FLUOROSIS

BONITE, J. | HIDALGO, M. | SALAZAR, M. 1