Shejay Lomongo

BSN - 2
Final Exam

Drugs acting on Reproductive System

A. Anti Inflammatory

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Ibuprofe
n 12/18/1 Analgesic tablet Anti- Contraindicate Nausea, Black box
998 (nonopioid) inflammatory, Relief signs d with allergy GI upset, warning: Be
GenNam 100mg analgesic, and and to ibuprofen, dyspepsia; aware that
e: NSAID antipyretic symptoms salicylates, or diarrhea or patients may
Ibuprofe 200mg activities rheumatoid other NSAIDS. constipatio be at
n Propionic largely related arthritis and n; increased risk
400mg to inhibition of osteoarthritis Black box drowsines of CV event,
BraNam (Rx) prostaglandin warning: s, GI
e: Advil Relief of mild Contraindicate
synthesis;exact dizziness, bleeding;monit
600mg to moderate d for treatment
mechanisms of vertigo, or accordingly.
(Rx) pain of
action are not insomnia
known. Inhibits perioperative Administer
800mg Treatment of pain after
both drug with food
(Rx) primary coronary
cyclooxygenas or after meals
dysmenorrhe artery bypass
e 1 and 2. if GI upset
capsule a graft. occurs.

200mg New Use cautiously Arrange for

Indication: with cv periodic
tablet, Prevention dysfunction, ophthalmologi
chewable and hypertension, c examination
treatment of peptic during long
50mg migraine ulceration, GI term therapy.
headache bleeding,
100mg pregnancy, Discontinue
Fever lactation, drug if eye
oral reduction impaired changes,
suspension hepatic o4 symptoms of
Prevention of renal function.
adverse hepatic
100mg/
reactions with impairment, or
5mL
DTP vaccine renal
in patients at impairment
40mg/mL
risk for
 seizures occur.

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Aspirin
10/18/2 Analgesic Tablet Analgesic and Contraindicate Nausea, Black box
GenNam 001 (nonopioid) antirheumatic Mild to d With allergy GI upset, warning
e: 81mg effects are moderate to salicylates heartburn;
Aspirin Anti- attributable to pain or NSAIDS; easy Do not use in
inflammato 325mg aspirin's ability allergy to bruising l, children and
BraNam ry Fever tartrazine; teenagers to
to inhibit the gum
e:Asperg 500mg synthesis of hemophilia, bleeding treat
Inflammatory
um Antiplatelet prostaglandins, bleeding chickenpox or
tablet, conditions
important ulcers, flu symptoms
Antipyretic delayed- mediators of hemorrhagic without review
Reduction of
release inflammation. states, blood for Reye's
risk of
Antirheum coagulation syndrome l, a
recurrent
atic 162mg defects, rare but fatal
TIAs pr CVA
hypoprothrom disorder.
325mg in patients
NSAID binemia,
with history of vitamin K
Give drug with
Salicylate 500mg TIA due to deficiency food or after
fibrin platelet
meals if GI
tablet, emboli or
upset occurs
chewable ischemic
stroke Give drug with
81mg full glass of
Reduction of
water to
tablet, risk of death
reduce risk of
enteric- or nonfatal MI
tablet or
coated in patients
capsule
with history of
lodging in the
81mg infarction or
esophagus
unstable
162mg angina Do not crush,
pectoris or and ensure
325mg suspected that patient
acute MI does not chew
650mg
SR
 Patients who preparations
capsule, have
liquid-filled undergone Do not use
(Vazalore) revasculariza aspirin that
tion has strong
81mg procedures, vinegar like
percutaneous odor
325mg transluminal
coronary
extended- angioplasty
release
capsule
(Durlaza
[Rx])

162.5 mg

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)

Meloxica 4/13/20 NSQID tablet Anti- Contraindicate Dizziness, Black box

m 00 (oxicam (Mobic) inflammatory, Relief from d with allergy drowsines warning Be
derivative) analgesic, and the signs and to aspirin or s (avoid aware that
GenNam 7.5mg antipyretic symptoms of meloxicam; for driving or patients may
e: activities pauciarticular perioperative using be at
Meloxica 15mg related to or pain after dangerous increased risk
m inhibition of the polyarticular coronary machinery for CV events,
tablet, oral enzyme pr bypass while GI bleeding;
BraNam disintegrati cyclooxygenas polyarticular surgery taking this monitor
e: Mobic ng (Qmiiz) e (COX), which course drug accordingly.
is required for juvenile
7.5mg the synthesis rheumatoid Administer
of arthritis in drugs with
15mg patients to 2 food or milk if
prostaglandins
and year older. GI upset
capsule
thromboxanes. occurs.
(Vivlodex) Relief from
the signs and Establish
5mg symptoms of safety
osteoarthritis measures if
10mg and CNS
rheumatoid disturbances
injection,
arthritis occur
IV aqueous
 Treatment of Monitor patient
dispersion ankylosing on prolonged
(Anjeso) spondylitis, therapy for
acute signs of GI
30mg/mL shoulder pain bleeding or
single-dose hepatic toxicity
vial

B. Anti Arthritis

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Diclofen Analgesic
ac 11/26/2 packet Inhibits Contraindicate Dizziness Black box
002. Anti- prostaglandin Acute or long d with allergy or warning Be
GenNam inflammato 50mg/ synthetase to term to NSAID, drowsines ware that
e: ry single-dose cause treatment of significant s patient may be
Diclofen packet antipyretic and mild to renal at increased
ac Antipyretic (generic, anti- moderate impairment, risk for CV
Cambia) inflammatory pain, pregnancy, events, GI
BraNam NSAID effects; the including lactation bleed, renal
e:Catafla Delivers exact dysmenorrhe insufficiency;m
m 50-mg mechanism is a onitor
dose when unknown accordingly
mixed in Rheumatoid
water arthritis Administer
drug with food
tablet Osteoarthritis
or after meals
Ankylosing if GI upset
50mg occurs
spondylitis
(generic)
Treatment pf Arrange for
capsule actinic periodic
keratosis in ophthalmologi
25mg c examination
conjunction
(Zipsor) during long
with sun
avoidance term therapy
diclofenac
sodium Topical
treatment of
 acute pain
due to minor
strains,
tablet, sprains,
delayed contusions
release
Postoperative
25mg inflammation
(generic) from cataract
extraction
50mg
(generic)

75mg
(generic)

tablet,
extended-
release

100mg
(generic)

capsule

18mg
(Zorvolex)

35mg
(Zorvolex)

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Etodolac Analgesic
5/27/19 (nonopioid) tablet Inhibits Contraindicate Dizziness Black box
GenNam 99 prostaglandin Acute or long d with or warning Be
e: NSAID 400mg synthesis by term use in significant drowsines aware that
Etodolac inhibiting the the renal s patients may
500mg enzyme, cyclo- management impairment, be at
BraNam oxygenase of sign and pregnancy, increased risk
e: capsule symptoms of lactation, for CV events
Lodine osteoarthritis, hypersensitivit and GI
200mg rheumatoid y to aspirin, bleeding;
arthritis, and etodolac, or
 juvenile other NSAIDS monitor
300mg rheumatoid accordingly.
arthritis
tablet, Give with food
extended- Management or after meals
release of pain if GI upset
occurs
400mg
Arrange for
500mg periodic
ophthalmologi
600mg c examination
during long
term therapy

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Fenoprof
en 10/15/2 Analgesic capsule Analgesic anti- Contraindicate Dizziness Black box
000 (nonopioid) inflammatory, Acute and d with or warning Be
GenNam 200mg and antipyretic long term significant drowsines aware that
e: NSAID activities treatment of renal s can patients may
Fenoprof 400mg largely related rheumatoid impairment, occur be at
en Propionic to inhibition of arthritis and pregnancy, increased risk
acid tablets prostaglandin osteoarthritis lactation, for CV events,
BraNam derivative synthesis by hypersensitivit GI bleeding,
e: Nalfon 600mg Relief of mild y to aspirin,
inhibiting monitor
to moderate fenoprofen, or
cyclooxygenas patients
pain ther NSAIDS
e;exact accordingly.
mechanisms of Unlabeled
action are not Administer
uses:
known drug with food
Treatment of
or after meals
juvenile
if GI upset
rheumatoid
occurs
arthritis;
symptomatic Arrange for
treatment of periodic
sunburn, ophthalmologi
migraine c examination
headache during long
term therapy
 C. Immunosuppressants

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Cycloph Alkylating
osphami 08/17/1 drug powder for Cytotoxic: Contraindicate Nausea, Arrange for
de 999 injection Interferes with Treatment of d with allergy vomiting, blood tests to
Antineopla replication of malignant to loss of evaluate
GenNam stic 500mg susceptible lymphomas, cyclophospha appetite; hematopoietic
e: cells. Not multiple mide, allergy darkening function before
Cycloph Nitrogen 1g specific to cell myeloma, to tartrazine, of the skin therapy and
osphami mustard cycle. leukemias, pregnancy, and weekly during
de derivative 2g mycosis lactation fingernails; therapy
fungoides, loss of hair
tablet
Immunosuppr
BraNam neuroblastom Warning Do
essive:
e: a, not give full
25mg Lymphocytes
Cytoxan adenocarcino dosage with in
are especially
sensitive to ma of the 4 wk after full
50mg
drug effects ovary, course of
retinoblastom radiation
a, carcinoma therapy due to
of the breast; the risk of
used severe bone
concurrently marrow
or depression;
sequentially reduced
with other dosage may
antineoplastic be needed.
drugs
Arrange for
Treatment of reduced
minimal dosage in
change patients with
nephrotic impaired renal
syndrome in or hepatic
children function

Warning
Epatient is well
hydrated
before
treatment to
reduce cystitis
Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing
drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Mycophe Immunosu
nolate 7/27/20 ppressants capsule Inhibits T- Contraindicate Nausea, Warning
mofetil 00 lymphocyte Prophylaxis d with allergy vomiting; Monitor renal
250mg activation; of organ to diarrhea; and liver
GenNam exact rejction in mycophenolat headache function before
e: tablet mechanism of patients e, pregnancy, and
action recieving lactation periodically
BraNam 500mg unknown, but allogeneic during therapy;
e: binds to renal, hepatic marked
Cellcept oral intracellular and heart decreases in
suspension proteij, which transplants; function may
may prevent intended to require dosage
200mg/mL be used
the generation change or
of nuclear concomitantly discontinuation
powder for
factor of with of therapy.
injection
activated T corticosteroid
cells, and s and Black box
500mg/vial
suppresses the cyclosporine warning
immune Protect patient
tablet,
activation and from exposure
delayed
response of T to infections
release
cells; inhibits and maintain
180mg proliferative sterile
responses of t technique for
360mg and b cells invasive
procedures;
risk for
infection exists

Black box
warning
Monitor patient
for possible
lymphoma
development
related to drug
action
Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing
drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Azathiop Immunosu
rine 20 ppressants tablet Suppressmedh Contraindicate Nausea Guve drug IV if
March ypersensetitviti Renal d with allergy and oral
GeName 1968 50mg es and alters homotranspla to vomiting adminustration
: antibody ntation: azathioprine; is not possible;
azathiop 75mg production; Adjunct for rheumatoid swticg to oral
rine exact prevention of arthritis route as soon
BraNam 100mg mechanisms of rejection patients as possible
e: action in previously
Azasan powder for Rheumatoid treated with Administer in
increasing
injection arthritis: Use alkylating divided daily
homograft
only with agents, doses or with
survival and
100mg/vial adults increasing food if GI
affecting
autoimmune
meeting theur risk for upset occurs
criteria for neoplasia;
disease not
classic pregnancy
clearly
rheumatoid
understood
artjritis and
not
responding to
conventional
management

Unlabeled
use
Treatment of
chronic
ulcerative
colitis
myasthenia
gravis,
Behcets
syndrome,
Crohn's
disease,
clinically
definite MS

D. Immune stimulant
Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing
drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
GenNam Solid
e: DMARDs Organ Calcineurin Hypersensitivit Injection:
Cyclosp Transplan inhibitor For the y monitor closely
orine Immunomo tation prophylaxis for at least 30
dulators; of organ Breastfeeding min
(Oral):
BraNam Immunosu rejection in
4-12 hr Suppresses
e: ppressants kidney, (RA/Psoriasis
; pre- cellular and use):
Neoral, liver, and
Sandim Calcineurin transplant: humoral Abnormal Risk of
15 mg/kg heart hepatotoxicity
Inhibitors immunity renal function,
mune, PO for 1 allogeneic and
(mainly T cells) uncontrolled
Gengraf dose transplants. nephrotoxicity
HTN,
1-2wk It is always malignancies
post- to be used
transplant: with adrenal (Psoriasis
Myelosuppres
15 corticosteroi use)
Concomitant sion may be
mg/kg/da ds. The drug
PUVA, UVB severe and
y PO may also be
radiation, coal prolonged;
divided used in the
tar, monitor
BID treatment of complete
methotrexate,
>Psoriasis chronic blood and
other
: rejection in immunosuppr platelet counts
1.25 patients essants
mg/kg PO previously
BID; may treated with
other Potential
increase increase risk
by 0.5 immunosup
for optic disk
mg/kg/da pressive
edema and
y agents.
infusion-
related
>Monitor anaphylactic
for signs reactions
and
symptoms
of infection;
severe and Some
fatal sepsis malignancies
caused by
as a result of
cyclosporine
bone
immunosuppre
marrow
ssion may be
suppression;
fatal (eg,
discontinue lymphoma)
if observed.
Serious and
fatal cerebral,
gastrointestina
l and
pulmonary
hemorrhage;
monitor
platelets and
coagulation
parameters
and treat
accordingly

Anticipate and
monitor for
signs and
symptoms of
tumor lysis
syndrome
occur; treat
promptly

Monitor for
and
discontinue
promptly if
systemic
inflammatory
response or
capillary leak
syndrome
suspected

Monitor for
signs and
symptoms of
infection;
severe and
fatal sepsis as
a result of
bone marrow
suppression;
 discontinue
therapy
promptly if
infection occur

Monitor for
and
discontinue if
venous
occlusive
disease of the
liver suspected

Monitor liver
enzymes and
discontinue
therapy at first
signs of
severe
hepatotoxicity;
fatal
hepatotoxicity
may occur

Monitor renal
function and
interrupt or
discontinue if
creatinine
levels increase
or acute renal
failure occur

3. Drugs for Eye

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing
drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Acyclovir Contraindicate
eye drop 12/30/2 Antiviral injectable Antiviral d with allergy Nausea, Systemic
002 solution activity; inhibits Initial and to acyclovir, vomiting, administratio
GenNam DNA recurrent seizures, heart loss of ns
Purine
e:Acyclo nucleoside 50mg/mL replication mucosal and failure, renal appetute, Ensure that
vir analogue cutaneous disease, diarrhea; the patient is
injection, HSV-1 and lactation, use jeadcahe, well hydrated
BraNam lyophilized HSV-2 and ccautiously dizziness
e: powder for varicella with Topical
Zovirax reconstituti zoster pregnancy administratio
on infections in n
immunocomp
500mg/vial romised Start treatment
patients as soon as
1000mg/ possible after
vial Severe initial onset of signs
and recurrent and symptoms
oral genitap
suspension herpes Wear rubber
infections in gloves or
200mg/ immunocomp finger cot
5mL romised when applying
patients drug
tablet
Herpes
400mg simplex
encephalitis
800mg
Treatment of
capsule neonatal
HSV
200mg infections

Acute
treatment of
herpes zoster
and chicken
pox
Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing
drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Atropine Anticholine
eye drop 07/09/2 rgic intramuscul Competitively Contraindicate Dizziness, Ensure
001 ar device blocks the Systemic d with confusion; adequate
GenNam Antidote effects of administrati hypersentivity dry mouth; hydration;
e: 0.25mg/ acetylcholine at on to blurred provide
atropine Antimuscar 0.3mL muscarinic anticholinergic vission, environmental
inic Antisialagogu drugs
cholinergic sensitivity control to
BraNam 0.5mg/ e for
receptors that to light; prevent
e: Antiparkiso 0.7mL preanesthetic
mediate the impotence; hyperpyrexia
AtroPen nian medication to
effect of difficultt in
1mg/0.7mL prevent or Have patient
parasympatheti urination
Belladonna reduce void before
c
alkaloid 2mg/0.7mL postganglionic
respiratiry taking
tract medication if
impulses,
Diagnostic injectable secretions urinary
depressing
agent solution retension is
salivary and Treatment of
(ophthalmi problem
bronchial parkinsonism
c 0.05mg/mL
secretions,
preparatio ; relieves
ns) 0.1mg/mL dilating the tremor and
bronchi, regidity
Parasymp 0.4mg/mL inhibiting vagal
atholytic influences on Restoration
0.8mg/mL the heart l, of cardiac
relaxing the GI rate and
1mg/mL and GU tracts, arterial
pressure
during
anesthesia
when vagal
stimulation
prodyced by
intra-
abdominal
traction
causes a
decrease in
pulse rate

Relief of
bradycardia
and syncope
due to
hyperactive
carotid sinus
 reflex

Antidote

Ophthalmic
prepartions

Diagnosticall
y to produce
mydriasis
and
cyxlopegia-
pupillary
dilation in a
cute in-
flammatiry
conditions of
the iris and
uveal tract

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Acetazol Antiepilepti
amide June c tablet Inhibits the Contrainidicat Increased Administer by
eye drop 25, enzyme Adjunctive ed with allergy volume direct IV if
1954 Antiglauco 125mg carbonic treatment pf to and parenteral use
GenNam ma drug anhydrase chronic open acetazolamide frequenct is
e: 250mg angel , antibacterial of necessary;IM
acetazol Carbonic glaucoma, sulfonamides, urination; use is painful
amide anhydrase powder for secondary or thiazides; dizziness,
(Rx) inhibitor injection glaucoma chronic feeling Give with food
noncongestuv faint on or milk if GI
BraNam Diuretic 500mg Preoperative e angle- upset occurs
arisung,
e: use in acute closure drowsines
Diamox Sulfonamid capsule, angle closure glaucoma s, fatigue;
Use caution if
Sequels e extended- glaucoma
sensitivitt
giving with
(DSC) (nonbacteri release when delay other drugs
to
ostatic) of surgery is with excretion
sunlight;GI
500mg desired to onhibited by
upset
lower IOP urine
alkanization
Edema
caused by Make oral
 heart failure l, liwuid form by
drug induced crushing
edema tablets and
suspending in
Centrenceph cherry,
alic epilepsy chocolate,
raspberry, or
Prophylaxis
others sweet
and
syrup
treatment of
acute
mountain
sickness

4. Drugs for Ear

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)

GenNam 12/04/1 Cephalosp capsule Third- Documented vomiting. Note

e: 997 orins generation Indicated for hypersensitivit differences
Cefdinir 300mg cephalosporin; Acute y nausea. between twice-
3rd inhibits Bacterial daily and
BraNam generation oral mucopeptide Otitis Media, stomach once-daily
e: suspension synthesis in Pharyngitis/T pain. dosing
Omnicef bacterial cell onsillitis,Acut regimens
125mg/ wall; typically e Maxillary diarrhea.
5mL bactericidal, Sinusitis,skin/
depending on Skin headache.
250mg/ Structure Use with
organism
5mL Infections vaginal caution in
susceptibility,
itching. patients with
dose, and
history of
serum or tissue
reddish penicillin
concentrations
colored allergy; if
stools. allergic
reaction to
cefdinir
occurs,
discontinue
therapy

Dosage
adjustments
may be
necessary if
CrCl is <30
mL/min

Bacterial or
fungal
overgrowth of
nonsusceptible
organisms
may occur with
prolonged or
repeated
therapy

Use caution in
patients with
history of
colitis

Antacids
containing
magnesium or
aluminum
interfere with
absorption of
cefdinir; if this
required
during therapy,
administer at
least 2 hr
before or after
antacid

Iron
supplements,
including
multivitamins
that contain
iron, interfere
with
absorption of
 cefdinir; if iron
supplements
required
administer at
least 2 hours
before or after
supplement

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)

GenNam 2/27/19 Penicillin oral Derivative of Documented nausea. Anaphylaxis

e: 98 solution ampicillin and treatment of hypersensitivit has been
Amoxicill Amino has similar genitourinary y to penicillins, vomiting. reported rarely
in 125mg/ antibacterial tract cephalosporin but is more
5mL spectrum infections, s, imipenem diarrhea. likely to occur
BraNam (certain gram- ear, nose, following
e: 200mg/ positive and and throat stomach parenteral
Amoxil 5mL gram-negative infections, pain. therapy with
organisms); lower penicillins
250mg/ similar respiratory vaginal
5mL bactericidal tract itching or Do not
action as infections, discharge. administer in
400mg/ penicillin; acts Helicobacter patients with
5mL pylori headache. infectious
on susceptible
bacteria during infections, mononucleosis
capsule rash, and.
multiplication pharyngitis, because of
stage by tonsillitis, and risk of
250mg swollen,
inhibiting cell skin and skin development
black, or
wall structure of
500mg "hairy"
mucopeptide infections. erythematous
tongue.
biosynthesis; skin rash
tablet
superior
500mg bioavailability
and stability to Do not
875mg gastric acid administer to
and has patients in the
tablet, broader absence of a
chewable spectrum of proven or
activity than suspected
125mg penicillin; less bacterial
active than infection
 because of
250mg penicillin risk of
against development
Streptococcus of drug-
pneumococcus resistant
; penicillin- bacteria
resistant
strains also
resistant to
Superinfection
amoxicillin, but
s with bacterial
higher doses
or fungal
may be
pathogens
effective; more
may occur
effective
during therapy;
against gram-
if suspected,
negative
discontinue
organisms (eg,
immediately
N meningitidis,
and begin
H influenzae)
appropriate
than penicillin
treatment

Chewable
tablets contain
aspartame,
which contains
phenylalanine

Use caution in
patients with
allergy to
cephalosporin
s,
carbapenems

Endocarditis
prophylaxis:
use for only
high-risk
patients, as
per recent
AHA
guidelines
 High doses
may cause
false urine
glucose test by
some
methodso

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)

GenNam 04/12/2 Cephalosp capsule Binds to one or Documented diarrhea, Endocarditis

e: 011 orins more of the Indicated with hypersensitivit prophylaxis is
Cephale 250mg penicillin Uncomplicate y dizziness, appropriate
xin 1st binding d Cystitis, only for high-
generation 500mg proteins, which Genitourinary tiredness, risk patients,
BraNam in turn inhibits Tract per American
e: 750mg synthesis of Infections, headache, Heart
Kefllex bacterial cell Association
oral Beta- stomach
wall guidelines
suspension Hemolytic upset,
Streptococcal
125mg/ Infections, abdominal
5mL pain, Adjust dose in
Bone severe renal
250mg/ Infections, joint pain, insufficiency
5mL (high doses
Otitis Media, vaginal may cause
tablet itching or CNS toxicity)
Skin/Skin
discharge,
Structure
250mg
Infections,
500mg Superinfection
Respiratory
s and
Tract
promotion of
Infections,
nonsusceptible
Streptococcal organisms
Pharyngitis may occur with
prolonged use
or repeated
 therapy

Prolonged
treatment,
hepatic or
renal disease,
or nutritional
deficiency may
be associated
with increased
international
normalized
ratio (INR)

Prolonged use
is associated
with fungal or
bacterial
superinfection

Use with
caution in
patients with
history of
hypersensitivit
y to penicillin

5. Vaccines

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Pneumo
nia 1977 Vaccine vaccine S. pneumoniae Previous Erythema, SECTIONS
vaccine capsular is indicated vaccination induration,
Inactivated 0.5mL (1 antigens for active with soreness Warnings
GenNam dose) stimulate active immunization pneumococcal at inj site
e: Bacterial for the vaccine, within Contraindicatio
immune
Pneumo prevention of 10 days of ns
response
coccal resulting in pneumococc immunosuppr
Previous
Vaccine production of al disease essive therapy Low grade
Polyvale caused by vaccination
nt endogenously the 23 fever with
produced serotypes pneumococcal
BraNam antibodies contained in vaccine, within
e: the vaccine 10 days of
Pneumo Rash immunosuppre
vax 23 ssive therapy

N/V
Cautions

Polysaccharid
Lymphade e capsular
nitis vaccine
against 23
strains of
pneumococci
ITP (90% of blood
relapse isolates & 85%
of isolates
found in sterile
sites)
Hemolytic
anemia

CDC now
recommends
Thromboc second dose
ytopenia after 5 years
for pts with
chronic renal
failure,
Anaphylac asplenia, HIV
toid infection,
reaction cancer, or
other
conditions
associated
Angioede w/immunosup
ma pression

Serum Splenectomy:
sickness administer at
due to least 2 wk
drug before
scheduled
 procedure
Guillain-
Barre
syndrome
Defer
vaccination in
persons with
moderate or
severe acute
illness

Exercise
caution and
appropriate
care in
individuals
with severely
compromised
cardiovascular
and/or
pulmonary
function in
whom a
systemic
reaction would
pose
significant risk

This vaccine
does not
replace the
need for
penicillin (or
other
antibiotic)
prophylaxis
against
pneumococcal
infection. In
patients who
require
penicillin (or
other
antibiotic)
prophylaxis
against3

Vaccine does
not replace
need for
penicillin (or
other
antibiotic)
prophylaxis
against
pneumococcal
infection; in
patients who
require
penicillin (or
other
antibiotic)
prophylaxis
against
neumococcal
infection, such
prophylaxis
should not be
discontinued
after
vaccination

Persons who
are
immunocompr
omised,
including
persons
receiving
immunosuppre
ssive therapy,
may have a
diminished
immune
response to
vaccine

Vaccine may
not be
 effective in
preventing
pneumococcal
meningitis in
patients who
have chronic
cerebrospinal
fluid (CSF)
leakage
resulting from
congenital
lesions, skull
fractures, or
neurosurgical
procedures

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Meningiti Vaccines
s 14 June IM Protection Protection Pain/ SECTIONS
vaccine 2012 Inactivated suspension against is indicated against redness/
invasive for active invasive swelling at Warnings
GenNam Bacterial 0.5mL/ meningococcal immunization meningococca the
e: syringe to prevent l disease is Contraindicatio
disease is injection
Meningo invasive conferred ns
conferred site,
coccal mainly by disease mainly by headache, Severe allergic
group b complement- caused by complement- fever, reaction after a
vaccine mediated Neisseria mediated chills, previous dose
antibody- meningitidis antibody- drowsines
BraNam dependent of
dependent serogroup B. s,
e: killing of N meningococcal
killing of N tiredness, B vaccine
Trumenb meningitidis
meningitidis joint/muscl
a,
e pain,
Bexsero
nausea,
loss of Cautions
appetite,
or diarrhea Epinephrine
may occur. and other
appropriate
agents used to
manage
immediate
allergic
reactions must
be
immediately
available
should an
acute
anaphylactic
reaction occur
following
administration

Syncope
reported;
procedures
should be in
place to avoid
injury from
fainting

Reduced
immune
response may
occur in
immunosuppre
ssed
individuals

Persons with
certain
complement
deficiencies
and persons
receiving
treatment that
inhibits
terminal
complement
activation (eg,
eculizumab)
are at
increased risk
for invasive
disease
caused by N
meningitidis
serogroup B
even if they
develop
antibodies
following
vaccination

Sufficient data
are not
available on
the safety and
effectiveness
of
interchanging
meningococcal
group B
vaccines to
complete the
vaccination
series

Bexsero: The
tip caps of the
prefilled
syringes
contain natural
rubber latex
which may
cause allergic
reactions in
latex sensitive
individuals
(Trumenba's
caps are not
made with
natural rubber
latex)
Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing
drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Flu Vaccines
vaccine Novem IM Mechanism of Hypersensitivit injection Use split or
ber Inactivated injection, Action is a vaccine y to eggs, site purified
GenNam 2015 regular indicated for sulfites reactions surface
e: Flu Viral strength Inactivated active (persons with antigen in
chills,
vaccine influenza virus immunization hives-only children
joint or
22.5mcg/ types A & B for the allergy to muscle
BraNam 0.25mL subunits prevention of eggs, can aches or
e:Afluria, influenza receive the pain,
Fluzone 45mcg/ disease inactivated Defer vaccine
headache
0.5mL caused by influenza with febrile
,
Convey active influenza A vaccine) illnesses until
tired
ID injection immunity via subtype feeling, illness is
stimulation of viruses and weakness resolved; may
27mcg/ production of type B virus , or. administer
0.1mL endogenously contained in fussiness vaccine with
(Fluzone produced the vaccine. or crying minor illnesses
Intradermal antibodies in without fever
) children. (eg, URIs)

Expected
immune
response may
not be
obtained in
immunocompr
omised
individuals,
including those
receiving
immunosuppre
ssive therapy

Syncope
(fainting) can
occur in
association
with
administration
of injectable
vaccines; can
 be
accompanied
by transient
neurological
signs such as
visual
disturbance,
paresthesia,
and tonic-
clonic limb
movements;
procedures
should be in
place to avoid
falling injury
and to restore
cerebral
perfusion
following
syncope by
maintaining a
supine or
Trendelenburg
position

Vaccination
may not
protect all
vaccine
recipients
against
influenza
disease

6. Immunization

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Polio Vaccine
1955 Immunizati IM/SC Inactivated Hypersensitivit Redness/ Before
 on This vaccine y to neomycin, receiving
GenNam Solution virus of 3 is used to streptomycin, swelling/ poliovirus
e: Polio strains; elicits prevent a polymixin B tendernes vaccine, tell
IPV 5mL/vial antibody certain virus s at the your health
response infection Defer if acute injection care
BraNam following (polio). Polio febrile illness site, fever, professional if
e: Ipol immunization is a virus that irritability, you are
affects mainly Concomitant and allergic to it; or
young methotrexate tiredness if you have
children. may occur. any other
These products allergies.
convey active
immunity via Before
stimulation of receiving this
production of vaccine, tell
endogenously your health
produced care
antibodies professional
your medical
history,
especially of:
The onset of current
protection from fever/illness,
disease is immune
relatively slow, system
but duration is disorders
long lasting (such as due
(years) to HIV
infection,
certain
cancers such
as
leukemia/lymp
homa, cancer
or radiation
treatment).Duri
ng pregnancy,
this vaccine
should be
used only
when clearly
needed.
Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing
drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Chicken Hypersensitivit
pox 1995 Vaccine vaccine Live, y to gelatin, swelling/ Avoid contact
Varicella Immunizati attenuated is a vaccine neomycin rash/ with high risk
on 1350 varicella virus indicated for pruritus/ individuals up
plaque stimulates active Pregnancy erythem to 5 wk after
GenNam forming active immunity immunization fever vaccination
e: units/0.5m to disease for the HIV: CD4+
Chicken L caused by prevention of count <200
pox varicella-zoster varicella in cells/mcL
Varicella individuals 12 Do not give
virus
months of Immunosuppr concurrently
BraNam age and essed or w/ any form of
e: older. immunodeficie immune
Varivax Conveys active nt patients globulin
immunity via with
stimulation of lymphomas,
production of leukemia, or
malignant Thermolabile:
endogenously store at
produced
neoplasms
affecting bone temperature -
antibodies 20°C or colder
marrow or
lymphatic
system
Syncope
Patients
accompanied
receiving
by transient
immunosuppr
visual
essive therapy
including disturbances,
immunosuppr weakness, or
essive doses tonic-clonic
of movements
corticosteroids reported with
injectable
Primary and vaccines
acquired
immunodeficie
ncy states
Postpone
administration
Current febrile
illness in patients with
moderate or
Active TB severe illness
with or without
fever; may
 administer to
patients with
mild illness
with or without
fever

Avoid
pregnancy for
3 months
following
therapy

Avoid taking
salicylates for
6 weeks after
vaccination
(may increase
risk of Reye's
syndrome

Name of Date Classificati Dose/ Mechanism of Specific Contraindicati Side Nursing

drug Ordere on of Drug Frequency Action Indication on Effects Precaution
(Generic d
& Brand)
Measles immunizati
(MMR) 1963, on injection, Live, contraindicate Fever include
1967, lyophilized attenuated is indicated d in persons keeping the
and powder for viruses for who are patient's nails
GenNam 1969, reconstituti stimulate active simultaneous severely short,
e: on immunity to vaccination immunocompr Syncope encouraging
Measles disease against omised as a long pants and
(MMR) ≥1000 caused by measles, result of sleeves to
TCID50/≥1 measles, mumps, and congenital prevent
BraNam 2,500 rubella, and rubella in disease, HIV Ataxia
scratching,
e: MMRII TCID50/≥1 mumps viruses individuals 12 infection, keeping skin
000 TCID50 months of advanced moist with
age or older leukaemia or
Pain at health care
lymphoma,
site provider
serious
recommended
malignant lotions, and
disease, or avoiding
treatment with sunlight and
high-dose Headache heat.
steroids,
alkylating
agents or
antimetabolite Rash
s

Lymphade
nopathy

Myalgia