Classification/ Contraindicat Side effects/

Drug Name Indications

Mechanism of Action ions Adverse Effects
Classification: Dexamethas It is •CNS: euphoria,
Generic Corticosteroid, Anti one is used contraindicate insomnia,
Name: inflammatory d if patients psychotic
Dexamethas to treat behavior,
have systemic
one Mechanism of Action:
conditions pseudotumor
fungal
The short term effects such infections, cerebri, vertigo,
Brand Name: as arthritis, headache,
of corticosteroids are hypersensitivit
Decadron paresthesia,
decreased vasodilation blood/horm y to
seizures,
Route: and permeability of one dexamethason
depression.
Oral capillaries, as well as disorders, e, or cerebral •CV:
administratio decreased leukocyte allergic malaria. hypertension,
n migration to sites of Another
reactions, edema,
inflammation.3 Corticos contraindicate arrhythmias,
Dosage: teroids binding to the
skin
d to thromboembolis
Dexamethas glucocorticoid receptor diseases, administer live m
one Tablets mediates changes in eye or live- • EENT:
0.5, 0.75, 1, gene expression that problems, attenuated cataracts,
1.5, 2, 4 and lead to multiple breathing vaccines glaucoma
6 mg USP, downstream effects problems, during the use • GI: peptic ulcer,
over hours to days. 3
of GI irritation,
Dexamethas bowel
Glucocorticoids inhibit dexamethason increase appetite,
one Oral disorders, pancreatitis,
neutrophil apoptosis e as the
Solution, 0.5 cancer, and nausea, vomiting
and demargination; immune
mg per 5 mL they inhibit immune • GU: increase
system is
and phospholipase A2, system urine glucose and
being
Dexamethas which decreases the calcium levels
disorders. It suppressed
one Intensol formation of •METABOLIC:
is also used and will less hypokalemia,
Oral arachidonic acid as a test for like form a hyperglycemia
Solution derivatives; they inhibit an adrenal strong enough •MUSCOSKELE
(Concentrat NF-Kappa B and other gland immune TAL: muscle
e), 1 mg per inflammatory disorder
response weakness
mL are for transcription factors; placing the •SKIN: Delayed
they promote anti- (Cushing's patient at risk. wound healing
oral
syndrome).
administrati inflammatory genes3 It is still • Other:
like interleukin-10. permissible to Susceptibility on
on. other infections.
Lower doses of administer
Frequency: corticosteroids provide killed or
Give 2.0 mg an anti-inflammatory inactivated
of effect, while higher vaccines,
dexamethaso doses are although it
ne orally immunosuppressive.3 H bears
every 6 hours igh doses of mentioning
for 48 hours. glucocorticoids for an that immune
extended period bind response may
to the be attenuated,
mineralocorticoid and it is
receptor, raising unpredictable
sodium levels and if immunity
decreasing potassium with
levels developing as
a result.