PHINMA-University of Pangasinan

College of Health Nursing

Drug Study
(simvastatin)
LIM, JULIANNE JEAVEN B.
2BSN-19
Name of Drug Mechanism Contraindication Side Effects Adverse effects Nursing Responsibilities
of action s

Brand: Zocor Inhibits The following are SE are the AE are the 1. Carry out lipid profile.
HMG-CoA contraindications following: following: 2. Assess cholesterol at
Generic: simvastatin reductase of the drug: - loss of - headache six weeks.
enzymes appetite - nausea 3. Perform liver function
Classification” which - active liver - upper-right - stomach pain tests in the first year of
HMG- CoA reduces the disease side stomach - constipation treatment.
reductase inhibitors, cholesterol - elevated hepatic pain - cold 4. In the case of
lipid-lowering synthesis in enzymes - tiredness symptoms: rhabdomyolysis with
agents/antilipidemic, the body that - pregnant or - itching stuffy nose, increased muscle
statins. may build up planning to be - dark urine sneezing or sore tenderness and creatine
on the walls - breastfeeding Clay-colored throat phosphokinase, therapy
of arteries woman stool should be discontinued.
and block the hypersensitivity - jaundice 5. Renal tests for the
blood flow to patients with impaired
the heart, renal function.
brain, and 6. Eye test before
other parts of treatment, after one
the body. month, then annually.

Patient teaching:
1. Advise patients that
blood and eye tests will be
necessary throughout
treatment.
2. Blurred vision, severe
gastrointestinal problems,
dizziness or headache
must be reported.
3. A low cholesterol diet
and exercise programme
are recommended.
4. Medication should be
stored in a closed
container in a cool, dry
dark place, our od the
reach of children.
5. Nurse should refer to
manufacturer’s summary
of product characteristic
and to appropriate local
guidelines