24/1/22 21:57 Leaky sewer pipes pollute urban streams and bays with drugs | Science News for

bays with drugs | Science News for Students

ENVIRONMENT

Leaky sewer pipes pollute urban streams and bays with drugs
Thousands of doses of medicines flow into just the Chesapeake Bay each year, a new study shows

In one new study, scientists took weekly water samples to test for medicines polluting streams.
LOVRO7 7 / E + / GE T T Y IMAGE S PLUS

By Laura Allen
November 24, 2021 at 6:30 am

The powerful drugs doctors prescribe shouldn’t end up in the water. Yet many do, a new study finds. This could be bad
news for fish and other water dwellers.

For more than 20 years, scientists have known that drugs can get into streams and rivers from sewage-treatment
plants. How? Some of the medicines we take come out in our pee and get flushed down the toilet. Wastewater-
treatment plants were never designed to remove most of these drugs. So they pass through the plants and later get
released into streams and other surface waters.

Most earlier studies sampled water coming out of those treatment plants or downstream from them. These are
reliable places to find drugs.

But not all sewage makes it to the treatment plant. If an incoming pipe has a crack, dirty water can leak into the soil.
Rainwater can then carry sewage into a nearby stream, including any drugs people had peed out. This new study

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sampled streams that did not receive treated sewage. This allowed the scientists to gauge what share of drugs in the
water came from leaking pipes.

Megan Fork is an ecologist at West Chester University in Pennsylvania. She and her team sampled streams around
Baltimore, Md., throughout a year. That allowed the researchers to estimate how much medicine was escaping from
leaky pipes. The researchers also used existing data to calculate the quantity of drugs exiting a sewage-treatment
plant that receives wastewater from this area.

Together, pollution from pipes and the plant added up to a lot medicine flowing downstream, Fork’s team found. And
the leaking pipes released different concentrations of drugs than the wastewater-treatment plant did. Her team
shared its findings September 7 in Environmental Science & Technology.

Most sewage treatment plants, like this one, were never designed to remove drugs from water. So the treated water they release may
contain the same polluting drugs that came in as part of the sewage.
HUOGUAN GLIAN G/ MOME N T / GE T T Y IMAGE S PLUS

Even small amounts may be toxic

“Most studies on pharmaceuticals collect data once or just a few times,” Fork notes. “But we had weekly data.” That
showed how the amount of drugs in the water changed over time. Sometimes the water was free of drugs. Other
times it contained many types. “It was not a constant drip,” she says. “It was more like big pulses, then none at all.”

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They tested for 92 different drugs. Thirty-seven turned up across all sampled streams. These included the non-
prescription pain reliever Tylenol. They also included medicines used to treat fungal infections and drugs to treat
depression. The drug that showed up most often was an antibiotic called trimethoprim. Overall, the more people that
lived near a stream, the more drugs Fork’s team detected in its water.

The highest amount they found was less than four millionths of a gram of Tylenol per liter of water. Most samples with
drugs contained just a few billionths of a gram of drug per liter of water. Some people may think tiny amounts of
drugs in the water aren’t a problem. But they can be, because drugs are designed to work in tiny amounts. Fork notes
that past research has shown small amounts — comparable to a few pinches of salt in an Olympic swimming pool —
can harm aquatic life.

Todd Royer agrees. “It doesn’t kill organisms right away,” he notes, “but they are affected.” He is an aquatic biologist at
Indiana University Bloomington. He did not take part in the new study.

After being exposed to drugs in water, crayfish are more likely to be eaten by predators. Other fish may lose the ability
to reproduce. Even bacteria and algae may be affected. One seven-year study of a Canadian lake documented the near
extinction of one fish species after chronic, low exposures to a hormone commonly found in birth-control pills.

Drugs in water may also build up in the bottom sediment. This slows their breakdown, which may extend how long
aquatic life are exposed to the drugs.

Lots of small doses can really add up

Fork and her team wanted to understand the impacts of drug pollution on Baltimore’s Inner Harbor, which is part of
the Chesapeake Bay. So the researchers calculated a year’s worth of drugs flowing into that water from the region’s
streams. The results were so high that the researchers triple-checked their numbers.

They found the equivalent of 30,000 adult doses of drugs to treat depression, 1,700 doses of drugs to fight infections
and 30,000 tablets of acetaminophen (Tylenol). Such numbers can now help scientists understand the big-picture
effect of drugs in water.

The study also found that wastewater-treatment plants and leaking pipes spew different mixes of drugs. Overall, more
drugs such as the antibiotic trimethoprim came out of the treatment plant than from leaking pipes. In fact, by their
calculations, a whopping 43 percent of all trimethoprim consumed in the Baltimore metro area made it into the water.
In contrast, acetaminophen came mostly from leaking pipes. Why? Treatment plants can remove most of this drug.

There is still much to learn about stream drug problems. But one thing is certain: Some of this pollution is preventable.
Researchers in the United Kingdom carried out a related study. It reported evidence that many people flush their
unused medicines down the toilet. “Our recent work indicated that down-the-drain disposal of pharmaceuticals
doubled since the last study in 2005,” its authors say. They, too, shared their findings September 7 in Environmental
Science & Technology.

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Ecologists warn that people should never flush away drugs. Instead, people should turn drugs in for disposal as a
hazardous waste. Or, if your community doesn’t have a drug-disposal program, the U.S. Food and Drug Administration
offers guidelines for safe home disposal. 

Communities must also fix leaking sewer pipes and upgrade wastewater-treatment plants to ensure the drugs that
come out in pee won’t escape into our waters. “This is an important issue for anyone who cares about the animals
living in the streams,” Fork says. It’s important for protecting animals in downstream waters. But keep in mind, she
adds: “People taking drugs they need is not the problem.” The problem is getting communities to manage their waste
properly.

CITATIONS
Journal: M.L. Fork et al. Dosing the coast: leaking sewage infrastructure delivers large annual doses and dynamic mixtures of
pharmaceuticals to urban rivers.Environmental Science & Technology. Vol. 55, September 7, 2021, p. 11637. doi: 10.1021/acs.est.1c00379.

Journal: B.  Kasprzyk-Hordern et al. Diagnosing down-the-drain disposal of unused pharmaceuticals at a river catchment level:
unrecognized sources of environmental contamination that require nontechnological solutions. Environmental Science & Technology.
Vol. 55, September 7, 2021, p. 11657. doi: 10.1021/acs.est.1c01274.

Journal: K.A. Kidd et al. Collapse of a fish population after exposure to a synthetic estrogen. Proceedings of the National Academy of
Sciences. Vol. 104, May 22, 2007, p. 8897. doi: 10.1073/pnas.0609568104.

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