The Prevalence of Preadolescent Eating Disorders in The United States

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Journal of Adolescent Health xxx (2022) 1e4

www.jahonline.org

Adolescent health brief

The Prevalence of Preadolescent Eating Disorders in the


United States
Stuart B. Murray, D.Clin.Psych., Ph.D. a, Kyle T. Ganson, Ph.D., M.S.W. b, Jonathan Chu c,
Kay Jann, Ph.D. d, and Jason M. Nagata, M.D., M.Sc. c, *
a
Department of Psychiatry & Behavioral Sciences, University of Southern California, Los Angeles, California
b
Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada
c
Division of Adolescent and Young Adult Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California
d
USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, California

Article history: Received May 13, 2021; Accepted November 23, 2021
Keywords: Eating disorders; Child eating disorders; Anorexia nervosa; Bulimia nervosa; Binge; Eating disorder

A B S T R A C T
IMPLICATIONS AND
CONTRIBUTION
Purpose: The prevalence of eating disorders (EDs) in young children remains relatively unknown.
Here, we aimed to assess the prevalence of anorexia nervosa (AN), bulimia nervosa (BN), binge ED
This study suggests that
(BED), and their subclinical derivatives, among 10- to 11-year-old children in the United States. full threshold eating dis-
Methods: Cross-sectional data from the year 1 sample of the nationwide Adolescent Cognitive orders are relatively un-
Brain Development study were extracted, and unadjusted prevalence of EDs was reported, as per common among 10- to 11-
DSM-5 criteria. year-olds in the United
Results: Among 10- to 11-year-old children in the United States, no cases of AN were reported. The States. Of all eating disor-
prevalence of BN was negligible, whereas the prevalence of BED was 1.1%. The prevalence of der phenotypes, binge
subclinical AN, BN, and BED was 6%, 0.2%, and 0.5%, respectively. eating disorder is the most
Discussion: BED is the most prevalent ED subtype among preadolescent children in the United prevalent. Subclinical
States, although subclinical markers for all ED subtypes are evident in this age range. eating disorders are more
Ó 2021 Society for Adolescent Health and Medicine. Published by Elsevier Inc. This is an open common, where some but
access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). not all diagnostic criteria
are met.

Eating disorders (EDs) are a constellation of burdensome, [3], and the noted elevation in psychiatric and medical morbidity
costly, and treatment refractory psychiatric disorders which in younger patients with EDs [4]. To date, one nationally repre-
portend elevated mortality and morbidity [1]. Although most sentative study in the United States reported the prevalence of
commonly developing in mid-adolescence, the prevalence of EDs EDs to be 0.1% in children aged 8e11 years of age [5], although
in younger children has remained largely unknown. This is a crucially, this study reflected DSM-IV diagnostic criteria, and did
particularly important concern given the greater prognosis not delineate prevalence trends by ED subtype. A recent study
afforded by early detection and intervention [2], with those reporting on the first wave of the Adolescent Brain Cognitive
treated within 3 years of illness onset showing a three-fold Development (ABCD) study reported the prevalence of EDs,
greater likelihood of weight normalization within 12 months delineated by subtype, in 9- to 10-year-old children, reporting
prevalence rates of 0.1% for anorexia nervosa (AN), 0.0% for
bulimia nervosa (BN), 0.6% for binge ED (BED), and 0.6% for other
Conflicts of interest: The authors have no conflicts of interest to declare. specified feeding and EDs [6]. However, these findings were
* Address correspondence to: Jason M. Nagata, M.D., M.Sc., 550 16th Street,
based on a fraction (approximately a third) of the baseline
4th Floor, Box 0110, San Francisco, CA 94158.
E-mail address: jason.nagata@ucsf.edu (J.M. Nagata). sample of the ABCD data set. This study aims to build on previous

1054-139X/Ó 2021 Society for Adolescent Health and Medicine. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://
creativecommons.org/licenses/by-nc-nd/4.0/).
https://doi.org/10.1016/j.jadohealth.2021.11.031
2 S.B. Murray et al. / Journal of Adolescent Health xxx (2022) 1e4

Table 1
An overview of the criteria used to determine eating disorder classifications

Eating disorder Diagnostic criteria

Anorexia nervosa (AN) (binge eating/purging  Fear surrounding becoming obese


subtype)  Emaciation
B <Fifth percentile of the BMI for age and sex

 Sense of self-worth connected to weight


 Use of weight control vomiting or other weight control methods or eating binges in the last
2 weeks
Anorexia nervosa (AN) (restricting subtype)  Fear surrounding becoming obese
 Emaciation
 Sense of self-worth connected to weight
 Absence of use of weight control vomiting or other weight control methods or eating binges in the
last 2 weeks
Bulimia nervosa (BN)  Presence of binge eating episodes
 Use of weight control vomiting or other weight control methods in the last 2 weeks
 Frequent use of weight control methods in the last 12 weeks
 Frequent binge eating episodes in the last 12 weeks
 Sense of self-worth connected to weight
Binge eating disorder (BED)  Presence of eating binges
 Frequent binge eating episodes
 Duration over the last 12 weeks
 Feelings of distress surrounding binge eating
 Absence of compensatory behaviors
 Absence of BN or AN diagnosis
Other specified feeding or eating disorder  Presence of emaciation AND absence of current AN or current AN in partial remission
(subclinical AN) B Applies only if fear of becoming obese and sense of self-worth connected to weight are absent

OR
 Presence of fear surrounding becoming obese, presence of sense of self-worth connected to
weight, presence of emaciation (no more than 1 BMI point over cutoff) AND absence of current AN
or current AN in partial remission
Other specified feeding or eating disorder  Presence of eating binges
(subclinical BN)  Presence of weight control methods
 Sense of self-worth connected to weight
 Absence of diagnosis for current AN, current AN in partial remission, current BN, current BN in
partial remission
Other specified feeding or eating disorder  Presence of eating binges
(subclinical BED)  Frequent binge eating episodes
 Presence of at least 1 of characteristics of binge eating
 Feelings of distress surrounding binge eating
 Absence of diagnosis for any other current eating disorder

BMI ¼ body mass index.

findings and report ED prevalence estimates (delineated by allows for results to be closely matched to the US population of
subtype and as per DSM-5 criteria [7]) and the bodyweight of 10- to 11-year-olds [8]. Results are based on this weighted
those afflicted, from the entire year 1 sample (ages 10e11 years) sample [8].
of the nationwide ABCD study.
Results
Methods
Among the sample of 11,082 10- to 11-year-old children,
Cross-sectional data of children aged 10e11 years from the 51.3% were boys. The sample was racially and ethnically
ABCD Study, a large, diverse, population-based sample, at year 1 diverse (53.9% non-Hispanic White, 19.5% Hispanic, 16.5% non-
(2017e2019, release 3.0) were analyzed in 2021. Institutional Hispanic Black, 5.6% non-Hispanic Asian/Pacific Islander, 3.2%
review board approval was obtained from the University of Native American, and 1.4% other race/ethnicity). No cases of
California, San Diego, and at each study site (N ¼ 21), and AN were present in this sample. The prevalence of BN was
caregivers provided written informed consent. ED diagnosis negligible. The prevalence of BED was 1.1% overall (1.2% in
was determined using parent/caregiver responses to the boys and 1.0% in girls) (Table 2). Among children with BED,
computerized Kiddie Schedule for Affective Disorders and the mean body mass index was 26.5 (standard deviation 5.5)
Schizophrenia (KSADS-5), based on DSM-5 criteria [7], and kg/m2 and the mean body mass index percentile was 92.1
subclinical EDs were determined by the presence of some but (standard deviation 14.3).
not all diagnostic criteria for AN, BN, and BED (Table 1). Unad- The prevalence of subclinical BN was marginally greater
justed prevalence of EDs was estimated. Analyses were con- than full threshold prevalence, at 0.2% in boys and girls. In
ducted using Stata 15.1, incorporating propensity weights, contrast, the prevalence of subclinical BED was marginally less
which matched key sociodemographic ABCD study variables to than that of full threshold presentations, at 0.6% in boys and
those of the American Community Survey, which is a large girls. The prevalence of subclinical AN was substantially
probability sample of US households. Although not designed to greater than that of full threshold presentations, at 6.5% in
be nationally representative, the use of propensity weights boys and 6% in girls.
S.B. Murray et al. / Journal of Adolescent Health xxx (2022) 1e4 3

Table 2
Prevalence of eating disorders among 11,082 10- to 11-year-old US children in the Adolescent Brain Cognitive Development study

Count Population count Prevalence 95% CI Adjusted Fa p value

Anorexia nervosa
Total 0 0 0.0% – – –
Boys 0 0 0.0% –
Girls 0 0 0.0% –
Bulimia nervosa
Total 6 2,826 0.0% 0.0%e0.0% 0.46 .50
Boys 3 1,052 0.0% 0.0%e0.0%
Girls 3 1,774 0.0% 0.0%e0.2%
Binge-eating disorder
Total 105 82,152 1.1% 0.9%e1.3% 0.47 .49
Boys 60 44,829 1.2% 0.9%e1.5%
Girls 45 37,323 1.0% 0.7%e1.4%
Other specified feeding and eating disorder: anorexia nervosa
Total 728 475,064 6.3% 5.8%e6.8% 1.00 .32
Boys 392 253,700 6.5% 5.8%e7.3%
Girls 336 221,364 6.0% 5.3%e6.8%
Other specified feeding and eating disorder: bulimia nervosa
Total 20 15,960 0.2% 0.1%e0.3% 0.16 .69
Boys 10 8,950 0.2% 0.1%e0.5%
Girls 10 7,010 0.2% 0.1%e0.4%
Other specified feeding and eating disorder: binge-eating disorder
Total 60 47,039 0.6% 0.5%e0.8% 0.06 .81
Boys 33 24,903 0.6% 0.4%e0.9%
Girls 27 22,136 0.6% 0.4%e0.9%

ABCD propensity weights were applied based on the American Community Survey from the US Census.
CI ¼ confidence interval.
a
The adjusted F statistic is a variant of the second-order Rao-Scott adjusted chi-square statistic.

Discussion subclinical markers may be substantially greater than the prev-


alence of full threshold diagnoses. However, the determination of
Among 10- to 11-year-old children in the United States, BED is subclinical AN in this data set may (i) include those with low
the most prevalent full threshold ED subtype. Broader evidence weight status without the cognitive markers of AN, and the
relating to the onset of EDs suggests that BED most commonly extent to which this conflates subclinical AN with constitution-
onsets in young adulthood [9]dthe latest among all ED ally thin yet nonpathological children is unclear, and (ii) exclude
phenotypesdalthough our findings indicate that BED is evident those with atypical AN whose weight is above the fifth percen-
in children as young as 10 years of age. One potential source of tile. Nevertheless, this greater preponderance of subclinical
the discrepancy between our findings and broader epidemio- markers of AN in boys discords with literature suggesting a
logical findings may relate to the inclusion of parental reports in greater prevalence of AN in girls and women, and data suggest-
arriving at diagnoses. A diagnosis of BED rests on an adequate ing a heightened preference for muscular body types in young
understanding of complex cognitive processes, such as what boys [11], and warrants further investigation.
constitutes a loss of control, and an adequate appraisal as to what Limitations of our study include the inability to assess other
represents an ‘abnormally large volume of food’ [7]. To that end, ED subtypes, some of which are known to onset earlier than
the inclusion of parental reports in informing diagnoses in the other ED phenotypes (e.g., avoidant and restrictive food intake
present study may facilitate an earlier detection of BED, given the disorder), and the noted ambiguities around the prevalence of
abstract concepts involved in diagnosis. subclinical ED behaviors in this age group.
Notably, and despite being linked the subsequent develop-
ment of obesity and cardiometabolic complications in adulthood Funding Sources
[10], our data indicate that even at 10e11 years of age, BED is
most prevalent among overweight and obese children. These S.B.M. was supported by the National Institutes of Health (K23
data serve to underscore the importance of early screening for MH115184). J.M.N. was supported by the National Institutes of
BED, and may potentially augment efforts to curb pediatric Health (K08HL159350) and the American Heart Association
obesity, and related sequelae, throughout later adolescence. In Career Development Award (CDA34760281). Data used in the
keeping with previous findings from earlier waves of the ABCD preparation of this article were obtained from the ABCD Study
study [6], we note that the prevalence of EDs is not skewed to- (https://abcdstudy.org), held in the NIMH Data Archive (NDA).
ward females, as has been widely reported in the ED field [11]. This is a multisite, longitudinal study designed to recruit more
Cumulatively, these findings illustrate that screening for EDs in than 10,000 children aged 9e10 years and follow them over
children, and for BED in particular, ought to extend to all genders 10 years into early adulthood. The ABCD Study was supported by
and include parental observations of child behavior. the National Institutes of Health and additional federal partners
The prevalence of subclinical ED presentations is noteworthy. under award numbers U01DA041022, U01DA041025,
Data relating to BN and BED suggest that subclinical markers may U01DA041028, U01DA041048, U01DA041089, U01DA041093,
be evident in children as young as 10e11 years of age and in boys U01DA041106, U01DA041117, U01DA041120, U01DA041134,
and girls alike. In the context of AN, these data suggest that U01DA041148, U01DA041156, U01DA041174, U24DA041123, and
4 S.B. Murray et al. / Journal of Adolescent Health xxx (2022) 1e4

U24DA041147. A full list of supporters is available at https:// [4] Campbell K, Peebles R. Eating disorders in children and adolescents: State
of the art review. Pediatrics 2014;134:582e92.
abcdstudy.org/nihcollaborators. A listing of participating sites
[5] Merikangas KR, He JP, Brody D, et al. Prevalence and treatment of mental
and a complete listing of the study investigators can be found at disorders among US children in the 2001-2004 NHANES. Pediatrics 2010;
https://abcdstudy.org/principal-investigators.html. ABCD con- 125:75e81.
sortium investigators designed and implemented the study and/ [6] Rozzell K, Moon DY, Klimek P, et al. Prevalence of eating disorders among
US children aged 9 to 10 years: Data from the Adolescent Brain Cognitive
or provided data but did not necessarily participate in analysis or Development (ABCD) study. JAMA Pediatr 2019;173:100e1.
writing of this report. [7] American Psychiatric Association. Diagnostic and statistical manual of
mental disorders. 5th ed. Arlington, VA: Author; 2013.
[8] Heeringa SG, Berglund PA. A guide for population-based analysis of the
References Adolescent Brain Cognitive Development (ABCD) study baseline data.
bioRxiv. 2020. Available at: https://www.biorxiv.org/content/10.1101/
[1] Santomauro DF, Melen S, Mitchison D, et al. The hidden burden of eating 2020.02.10.942011v1. Accessed July 15, 2021.
disorders: An extension of estimates from the Global Burden of Disease [9] Kessler RC, Berglund PA, Chiu WT, et al. The prevalence and correlates of
Study 2019. Lancet Psychiatry 2021;8:320e8. binge eating disorder in the world health organization world mental health
[2] Curin L, Schmidt U. A critical analysis of the utility of an early intervention surveys. Biol Psychiatry 2013;73:904e14.
approach in the eating disorders. J Ment Health 2009;14:611e24. [10] Mitchell JE. Medical comorbidity and medical complications associated
[3] McClelland J, Hodsoll J, Brown A, et al. A pilot evaluation of a novel first with binge-eating disorder. Int J Eat Disord 2016;49:319e23.
episode and rapid early intervention service for eating disorders (FREED). [11] Murray SB, Nagata JM, Griffiths S, et al. The enigma of male eating disor-
Eur Eat Disord Rev 2018;26:129e40. ders: A critical review and synthesis. Clin Psychol Rev 2017;57:1e11.

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