Class Subclass MOA Drug Example Example

of illness
(&
organism)
treated
Aminoglycos N/A Binds to Streptomycin Endocardi
ides 30S tis (S.
ribosomal aureus, S.
subunit, viridans)
inhibiting
protein
synthesis
Cephalospor 1st Inhibits cephalexin Nonpurul
ins generation cell wall ent
synthesis cellulitis
(S.
aureus),
exctensive
impetigo
(S. aureus,
S.
pyogenes
A)
2nd cefuroxime Meningitis
generation (H.
influenzae
)
3rd ceftriaxone Gonococc
generation al
cervicitis
(N.
gonorrhoe
ae)
cefdinir Preseptal
cellulitis
(S.
aureus),
acute
cystitis
(peds)
4th cefipime Severe
generation mastitis
(MSSA)
 5th ceftaroline Diabetic
generation wound
(MRSA)
PCN PCN Inhibits PCN V Strep
peptidogly pharyngiti
can s (S.
Pyogenes)

PCN G Syphilis (T.

pallidum)
AminoPCN Enhanced amoxicillin AOM (S.
cell pneumoni
membran ae)
e activity Amox/clavulanate Sinusitis
(S.
penumoni
ae, H.
influenzae
, M.
Catarrhali
s)
Penicillinase Stable in dicloxacillin Mild-mod
-resistant presence (or early)
PCN of mastitis
penicillina (MSSA)
se
Antipseudo Unclear Piperacillin/ Postpartu
monal PCN tazobactam m
endometri
tis (S.
pyogenes
B)
Tetracycline N/A Binds to Minocycline Acne
s 30S vulgaris
ribosomal (C. acnes)
subunit,
inhibiting
protein
synthesis
Quinolones “newer” Inhibits ciprofloxacin Pyeloneph
(Fluroquinol (not a true DNA ritis (E.
ones) subclass) gyrase Coli, S.
and saprophy
 topoisome ticus)
“older” (not rase IV levofloxacin CAP
a true (patients
subclass) with
comorbidi
ties) (S.
pneumoni
ae or M.
pneumoni
ae – want
to cover
multiple
bacteria)
Nitrofuranto N/A Inhibits Nitrofurantoin Acute
in DNA, RNA, cystitis in
protein, adults and
and cell peds (E.
wall Coli)
synthesis
Macrolides N/A Binds to Azithromycin Chlamydia
50S cervicitis
ribosomal (C.
subunit, trochoma
inhibiting tis), CAP
protein (m.
synthesis pneumoni
ae)
Sulfonamide N/A Competes Sulfamethoxole/ Acute
with PABA trimethoprim cystitis (E.
and Coli)
inhibits FA
synthesis
Glycopeptid N/A Inhibits Vancomycin C. Diff
es cell wall colitis (C.
and RNA Difficile)
synthesis

Mneomic to remember classes of antibiotics 

“Antiobiotics Can Protect The Queens’ Neighbors Men Servants & Guards”