MULTIPLE CHOICE QUESTION

1. Increase in number of cells in a tissue is called.

A. Hypertrophy
B. Hyperplasia
C. Aplasia
D. Hypoplasia
Ans. B
2. hypertrophy is
A. increase in number of cells
B. increase in size of cells
C. uncontrolled multiplication
D. spreading to other side
Ans. B
3. Name the most common type of cancer that kills men in the world?
A. Lung Cancer
B. Prostate Cancer
C. Liver Cancer
D. Colon and Rectum Cancer
Ans. A
4. Name cancer that starts in the skin or the tissues that line other organs?
A. Leukemia
B. Pancreas
C. Carcinoma
D. None of the above
Ans. C
5. Name cancer that occurs in the bone marrow and creates blood cells?
A. Sarcoma
B. Myeloma
C. Lymphoma
D. Leukemia
Ans. D
6. The abnormal growth of cells in the body is known as...........
A. Cancer
B. Malignancy
C. Both A and B
D. Only A
Ans. C
7. The most common types of treatment for Cancer are...
A. Chemotherapy
B. Surgery
C. Radiation Therapy
D. All the above
Ans. D
8. Name the cancer of connective tissues or cancer that occurs in the connective tissues in the
body?
A. Lymphoma
B. Sarcoma
C. Carcinoid
D. Medulloblastoma
Ans. B
9. Name the most common cancer in the world, due to which women died?
A. Breast Cancer
B. Ovarian Cancer
C. Rectal Cancer
D. Vaginal Cancer
Ans. A
10. Stomach Cancer is also known as...
A. Gastric Cancer
B. Oesophageal Cancer
C. Diaphragm Cancer
D. Duodenum Cancer
Ans. A
11. When a thin membrane that covers the chest and abdomen starts to multiply in a rapid
and uncontrollable way, then what type of cancer is formed in the body?
A. Mesothelioma
B. Mycosis
C. Merkel Cell Carcinoma
D. None of the above
Ans. A
12. Name the Cancer which is known as The Silent Killer?
A. Stomach Cancer
B. Liver Cancer
C. Lung Cancer
D. Brain Cancer
Ans. B
13.What percentage of breast caners are associated with known gremlin mutations :
a) 5
b) 10
c) 15
d) 20
Answer : B 
14.The HER2 oncogene is located on :
a) Chromosome 16q12
b) Chromosome 17q12
c) Chromosome 12q17
d) Chromosome 12q16
Answer : B
15.In Which phase of cell cycle is DNA replicated?
A. C1 phase
B. S phase
C. G2 phase
D. M phase
Ans : B
16. Most commonly seen carcinoma in elderly male is
A. Oral
B. Lung
C. Tongue
D. Prostate
Ans: D
17. Ca prostate develops in which region of the prostate ?
A. Transition
B. Peripheral zone
C. Central zone
D. Both a& c
Ans: B
18. Most common histologic type of cancer of cervix is
A. Squamous cell carcinoma
B. Ductal cell carcinoma
C. Epithelial cell carcinoma
D. Full thickness carcinoma
Ans:A
19. Organism responsible for Ca.cervix is
A. Myxovirus
B. Papillovirus
C. Rhino virus
D. Rota virus
Ans: B
20. which one of the following cancers does not metastasize commonly to liver?
A. Breast
B. Lung
C. Colon
D. Prostate
Ans: D
21. Principle behind hormonal therapy in prostate cancer is
A. Reduce testosterone production
B. Improve testosterone reduction
C. Improve 5 alpha reductase production
D. Reduce 5 alpha reductase production
Ans: A
22. Hormonal therapy is used in cancer of prostate is also known as
A. Androgen deprivation therapy
B. Testosterone therapy
C. Estrogen therapy
D. Antagonising therapy
Ans: A
23. Respite care refers to
A. Pallitative care
B. Rehabilitation
C. Part-time supervision of patients with chronic condition
D. End-of-life care
Ans: C
24. Treatment that uses light and energy aimed at an exact tissue location and depth to
vaporize cancer cells is :
A. En bloc dissections
B. Photoablation
C. Debulking
D. Diathermy
Ans: B
25. Earliest Sign in testicular cancer is
A. Frequency of urine
B. Painless enlargement of testes
C. Urgency
D. Dysuria
Ans: B
26. Pallitative care is
A. Radiation therapy used to treat cancer
B. Surgery followed by chemo and radiation
C. Give as a first step to shrink the tumor before giving main treatment
D. Relieve symptom and improves quality of life
Ans: D
27. Radio sensitive tissue is minimum in ……… tissue
A. Blood
B. Bone
C. Lung
D. Thyroid
Ans: B
28. least affected by radiation therapy is …….
A. Neurons
B. Gonads
C. Cartilages
D. Lymphocytes
Ans: C
29. Radioisotope used for cancer treatment is
A. Strontium-89
B. Samarium-153
C. Radium-223
D. All the above
Ans: D
30. Most Common side effect associated with radiation therapy to the neck is
A. Alopecia
B. Dermatitis
C. Haemoptysis
D. Sore throat
Ans: D
31. An external source of ionizing radiation is pointed at a particular part of the body is
known as
A. Teletherapy
B. Brachytherapy
C. Chemotheraphy
D. Microwavetherapy
Ans:A
32. Anticancer drugs weaken host defence by:
A. Damaging respiratory and gut epithelia
B. Inducing granulocytopenia
C. Altering resident microbial flora
D. Both ‘A’ and ‘B’ are correct
Answer: [  D  ]
 
33. Practically all antineoplastic drugs can produce the following toxic effects except:
A. Depression of leucocyte count
B. Mucositis
C. Cardiomyopathy
D. Oligozoospermia
Answer: [  C  ]
 
34. Alkylating agents exert cytotoxic action by inducing:
A. Breakage of DNA strand
B. Cross linking of DNA strands
C. Abnormal pairing of purine and pyrimidine bases
D. All of the above
Answer: [  D  ]
 
35. The following is true of cyclophosphamide except:
A. It is highly reactive and a vesicant on contact
B. It is a prodrug
C. It has marked immunosuppressant property
D. It frequently causes alopecia and cystitis
Answer: [  A  ]
 
36. The most important target of action of chlorambucil is:
A. Myeloid tissue
B. Lymphoid tissue
 C. Neural tissue
D. Skin
Answer: [  B  ]
 
37. Which of the following neoplastic diseases is almost curable by chemotherapy:
A. Bronchogenic carcinoma
B. Choriocarcinoma
C. Malignant melanoma
D. Colorectal carcinoma
Answer: [  B  ]
 
38. The following anticancer drug has high emetogenic potential:
A. Vincristine
B. Chlorambucil
C. 6-Mercaptopurine
D. Cisplatin
Answer: [   D  ]
 
39. The following is true of cancer chemotherapy:
A. Anticancer drugs increase the risk of developing leukaemias and lymphomas
several years later
B. All anticancer drugs are highly emetogenic
C. Growth fraction of cancers is higher than any nomral tissue of the body
D. All of the above are correct
Answer: [   A  ]
 
40. Methotrexate has the following attributes except:
A. It is cell cycle specific and kills cells in the S phase
B. Its toxicity primarily affects bone marrow and epithelial structures
C. Folic acid reverses its toxic effects
D. It is the drug of choice for choriocarcinoma
Answer: [   C  ]
 
41. The following antineoplastic drug is a mitotic inhibitor and causes metaphase arrest:
A. Busulfan
B. Vincristine
C. Cytarabine
D. Procarbazine
 Answer: [   B  ]
 
42. Vinca alkaloids exert antitumor activity by:
A. Activating topoisomerase II to cause breaks in DNA strands
B. Crosslinking DNA strands
C. Inhibiting DNA mediated RNA synthesis
D. Inhibiting polymerization of tubulin to form intracellular microtubules
Answer: [   D  ]
 
43. The following cytotoxic drug acts by inhibiting depolymerization of tubulin and thus
producing abnormal arrays of microtubules:
A. Paclitaxel
B. Vinblastine
C. Etoposide
D. Mitoxantrone
Answer: [   A  ]

44. What is the theme of the World Cancer Day 2021?

A. I am and I will
B. Close the Care Gap
C. 'We can. I can
D. Not Beyond Us
Answer: A
45. World Cancer Day 2022-2024 theme: 
A. I am and I will
B. Close the Care Gap
C. 'We can. I can
D. Not Beyond Us
Answer: B
46. What is the theme of the World Cancer Day 2018?
A. I am and I will
B. Close the Care Gap
C. 'We can. I can
D. Not Beyond Us
Answer: C
47. What is the theme of the World Cancer Day 2015?
A. I am and I will
B. Close the Care Gap
 C. 'We can. I can
D. Not Beyond Us
Answer: D
48. Which of the following is the most accurate and safest technique to diagnose cancer?
A. Biopsy
B. CT scan
C. MRI
D. Radiography
Answer: C
49. Cancer detection is not based on which of the following tests or studies?
A. Biopsy
B. Widal test
C. Histopathological studies
D. Bone Marrow tests
Ans: B
50. What is the use of monoclonal antibodies?
A. They are used to detect cancerous cells
B. They are used to increase the blood platelets count
C. They are used to treat AIDS
D. They are used to give a three-dimensional image of the internal organs of the body
Ans: A