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Structure of An Ovum Structure and Function of A Sperm
Structure of An Ovum Structure and Function of A Sperm
Structure of An Ovum Structure and Function of A Sperm
CORONA RADIATA
CENTRIOLE
o Surrounds an egg
o Consists of two or three layers of cells from o Located between the head and the
the follicle. midpiece.
o They are attached to the zona pellucida Essential for movement of the pronuclear
for union with the female genome.
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NCM 109: MATERNAL AND CHILD HEALTH NURSING
INFERTILITY
TAIL (FLAGELLUM)
o A term used to describe the inability to
o It is divided into several parts that include: conceive a child or sustain a pregnancy to
1.) Connecting Piece – this is the part that birth.
connects the flagellum to the sperm o A couple is said to be infertile if they have
head not become pregnant after at least 1 year
2.) Midpiece – contains mitochondria and of unprotected coitus.
provides energy required for movement
SUBFERTILITY
3.) Principal Piece (Axial filament)
4.) End piece o Term used rather than “infertility” because
it denotes that couple has a potential to
conceive.
o Affects 8% to 12% of couples desiring
children
o A lessened ability to conceive
PRIMARY SUBFERTILITY
o There have been no previous conceptions.
MOTILITY SECONDARY SUBFERTILITY
o There has been a previous viable
o Two types of physiological motility: pregnancy but the couple is unable to
ACTIVATED MOTILITY conceive at present because of a known
o The type observed in the early stages of condition.
motility (in the epididymis as well as freshly
ejaculated sperm). STERILITY
o Gentle movement of the sperm's flagella
from one side to another as the cell moves o Inability to conceive due to known cause
along what may appear to be a straight such as absence of a uterus.
path. o The inability to create offspring (children)
as a result of a procedure such as tubal
HYPERACTIVATED MOTILITY
ligation, hysterectomy, or vasectomy.
(HYPERACTIVATION)
o This type of motility occurs is in the TUBAL LIGATION
female reproductive tract (site of o Also known as “getting your tubes tied,”
fertilization). is a procedure in which a woman’s
o Movement is more erratic and more fallopian tubes are blocked or partially
energy is used for movement. removed, preventing the chance for
sperm and eggs to meet.
o Serves to prevent the sperm cell from
getting trapped, propelling through the VASECTOMY
reproductive tract (of the female) as well o Similar to a tubal ligation, but for males
as enhancing sperm penetration into the the tube that allows sperm to travel out
egg (oocyte). from the testicle is partially removed.
o PREDISPOSING FACTORS:
Age often increases Subfertility
the risk of infertility. o Cardiovascular diseases due to stress-
o Infertility can be caused by poor sexual or induced mechanisms are mediated
lifestyle habits that are easily remedied. primarily through increased adrenergic
For example: The couple may be using a sexual stimulation.
lubricant that interferes with the o Both adrenaline and cortisol (increased
survival of the man's sperm. during stress) affect heart and blood
pressure.
o Too much adrenaline makes blood
PREDISPOSING FACTORS: Infertility pressure to go up which in turn affects the
PREDISPOSING FACTORS: Subfertility functioning of the heart since the heart has
o Infertility can be caused by poor sexual or to pump harder and faster.
lifestyle habits that are easily remedied. o Cortisol also alters bone mineral density
- They may not be having sex often thus affecting the development of new
enough. bones in the body.
- Heavy use of alcohol, tobacco or drugs.
- Starvation diets or anorexia in the
woman. SUPPRESSION OF IMMUNE SYSTEM
- Tight underwear or pants in men.
o Stress: o The high levels of stress hormones
- In a woman, this may cause her periods suppress the release of cytokines
to be irregular. chemicals secreted by Th cells (T helper
- In a man, stress may reduce his sperm cells- a type of T lymphocytes).
count. o Cytokines regulate both cell-mediated and
humoral immune response in the body.
IMPACTS OF STRESS ON THE BODY
REPRODUCTIVE SYSTEM (Men and Women)
PREDISPOSING FACTORS:
DIGESTIVE Subfertility
SYSTEM
o Disturbed eating habits o Chronic stress may decrease libido and
o acid reflux may even cause erectile dysfunction or
o Diarrhoea or constipation impotence in man.
o Obesity which is linked to a host of other o Testosterone levels can drop to an extent
health problems. that can interfere spermatogenesis (sperm
o Extreme stress can also be associated production).
with diabetes. o In women stress can affect menstrual
o This is because excessive cortisol can cycle.
affect the activity of insulin. o It can lead to irregular, heavier or more
o The body can also become resistant to painful periods.
insulin. This can lead to diabetes.
NURSING IMPLICATIONS
EXERCISE
o Exercising 30 minutes per day by walking – abdominal discomfort
or doing mild aerobics also helps to – Distention
regulate blood glucose levels and – Bloating
increase fertility, – Nausea & vomiting
POSSIBLE
– Stress may play a role in limiting – breast tenderness
ADVERSE
ovulation as this may lower – vasomotor flushing
EFFECT
hypothalamic secretion of the – ovarian enlargement
gonadotropin-releasing hormone – ovarian overstimulation
(GnRH), which then lowers the – multiple births
production of LH and FSH, which – visual disturbances
leads to anovulation.
1. Ensure women have
DRUGS THAT AFFECT GONADAL FUNCTION & had a pelvic
FERTILITY examination and
baseline hormonal
studies before therapy.
ANDROGENS 2. Review medication
scheduling.
o To replace deficient male hormones 3. Urge women to use a
ESTROGENS calendar or some other
system to mark their
o To replace deficient hormones to control treatment schedule and
hormonal balance. also to determine and
plot ovulation.
CONCEPTION ENHANCERS 4. Remind patients that
timing intercourse with
OVULATORY STIMULANT ovulation is important
CLOMIPHENE CITRATE (Clomid) NURSING for achieving
o A follicle-maturing agent used during the IMPLICATIONS pregnancy.
5th – 10th day of menstrual cycle 5. Advice patient 24-hour
An estrogen agonist urine samples may be
ACTION commonly used to stimulate periodically necessary.
the ovary. 6. Caution patients to
o Initially, 50 mg/day orally report any bloating,
for 5 days (started anytime stomach pain, blurred
if no menstrual flow has vision, unusual
occurred recently or about bleeding, bruising, or
the fifth day of the cycle if visual changes.
menstrual flow is 7. Inform patients that
occurring). therapy can be repeated
DOSAGE
o If ovulation does not occur for a total of three
with this initial therapy, the courses; if no results
drug can be followed by a are obtained, therapy
prescription of 100 mg/day will be discontinued at
for 5 days started as early that point.
as 30 days after the initial
course of therapy.
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NCM 109: MATERNAL AND CHILD HEALTH NURSING
ASSISTED REPRODUCTIVE TECHNIQUES
OVULATORY STIMULANTS
o If ovulation, sperm production, or sperm
Inhibits release of motility problems cannot be corrected,
Bromocriptine
prolactin which can assisted reproductive strategies are the next
(Parlodel)
cause unovulation. step.
Therapeutic insemination
Acts similarly to FSH – Alternative or IUI is the instillation of
Human Menopausal
or LH to stimulate sperm from a masturbatory sample
Gonadotropin
growth and maturation into the female reproductive tract
(Pergonal)
of ovarian follicles. by means of a cannula to aid
conception at the time of ovulation
Gonadotropin- Used when
releasing hormone clomiphene is IVF
(GnRH) ineffective Gamete intrafallopian transfer (GIFT)
Zygote intrafallopian transfer (ZIFT)
Surrogate embryo transfer
FOR HYPERPLASIA DEFECTS
THERAPY FOR INCREASING SPERM COUNT
o Reduces AND MOTILITY
endometrial 1. Abstain from coitus for 7 to 10 days at a
Danazol (Cyclomen) hyperplasia time to increase the count.
o Inhibits estrogen 2. Ligation of a varicocele (if present)
defects. 3. Avoid recreational marijuana use
4. Wear looser clothing
o Reduces adrenal 5. Avoid long periods of sitting, and
Prednisone
hyperplasia
6. Avoid prolonged hot baths
THERAPY FOR UTERINE CONCERNS o Birth control pills, patches and vaginal rings
1. LUTEAL PHASE DEFECT help control the hormones responsible for
o This can be corrected by progesterone the buildup of endometrial tissue each
vaginal suppositories begun on the month.
third day of a woman’s temperature o Using hormonal contraceptives — especially
rise and continued for the next 6 continuous-cycle regimens — may reduce or
weeks (if pregnancy occurs) or until a eliminate pain in some cases.
menstrual flow begins.
2. MYOMA (FIBROID TUMOR) OR GONADOTROPIN-RELEASING HORMONE (Gn-RH)
INTRAUTERINE ADHESIONS AGONISTS AND ANTAGONISTS
o A myomectomy, or surgical removal of
the tumor and adhesions, can be o These drugs block the production of ovarian-
scheduled (Bailey, Jaslow, & Kutteh, stimulating hormones, lowering estrogen
2015). levels and preventing menstruation.
o If the growth is small, this can be done o This causes endometrial tissue to shrink.
by a hysteroscopic ambulatory o Because these drugs create an artificial
procedure. menopause, taking a low dose of estrogen or
o the woman may be prescribed progestin along with Gn-RH agonists and
estrogen for 3 months as another antagonists may decrease menopausal side
method to prevent adhesion formation effects, such as hot flashes, vaginal dryness
o an intrauterine device (IUD) may be and bone loss.
inserted to prevent the uterus from
o Menstrual periods and the ability to get
touching and forming new adhesions
pregnant return when you stop taking the
– Be certain she has a good
medication.
explanation of the IUD’s purpose
and that it can be easily removed in
about 1 month’s time.
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NCM 109: MATERNAL AND CHILD HEALTH NURSING
THERAPY FOR VAGINAL AND CERVICAL together, these become sufficient to create
CONCERNS subfertility.
1. If sperm do o A woman may be prescribed o It is obviously discouraging for couples to
not appear to low-dose estrogen therapy complete a fertility evaluation and be told
survive in to increase mucus their inability to conceive cannot be
vaginal production during days 5 to explained.
secretions 10 of her cycle. o Offer active support to help the couple find
because o Conjugated estrogen
alternative solutions at this point, such as
secretions (Premarin) is a type of
continuing to try to conceive, using an
are too scant estrogen prescribed for this
or tenacious purpose. assisted reproductive technique, choosing
to adopt, or agreeing to a child-free life.
2. If a vaginal o The infection will be treated
infection is according to the causative
present organism based on culture ASSISTED REPRODUCTIVE TECHNIQUES
reports.
o If ovulation, sperm production, or sperm
o Vaginal infections such as
trichomoniasis and mobility problems cannot be corrected,
moniliasis tend to recur, assisted reproductive strategies are the
requiring close supervision next step for a couple to consider.
and follow-up.
BEFORE BEGINNING ANY OF THESE
o If the woman’s sexual
PROCEDURES:
partner is the source of
1. Urge a woman to be in excellent health by
infection, and is therefore
discontinuing smoking or recreational drug
reinfecting her, the partner
behaviors
needs antibiotic therapy as
2. Ingesting a diet high in protein
well.
3. A BMI within a normal range of 18.5 to 24.9.
o Caution women who are
4. Tests for HIV and hepatitis C
prescribed metronidazole
5. A hormone profile including levels of FSH,
(Flagyl) for a Trichomonas
LH, estrogen, and progesterone to test for
infection;
ovarian reserves (whether ovaries have the
– Although no studies have
capacity to produce multiple oocytes)
shown fetal
6. Intravaginal sonogram to visual usual
malformations after its
structures.
use, it may be teratogenic
7. Consider the budget
early in pregnancy and
8. Availability of health insurance because the
therefore should not be
couple may not be able to afford these
continued if the woman
therapies
suspects she has
9. Consider their religion or cultural beliefs
become pregnant.
because they may find these unacceptable
procedures. LGBT couples may also feel
uncomfortable seeking reproductive advice.
UNEXPLAINED SUBFERTILITY 10. In all instances, culturally sensitive care is
required by the nurse
o In a small percentage of couples, no known
cause for subfertility can be discovered.
o It may be that the problem of one partner
alone is not significant, but when combined
with a small problem in the other partner,
o Common causes:
PATHOPHYSIOLOGY OF LEFT HEART FAILURE Pulmonary valve stenosis
Atrial & ventricular septal defects
Eisenmenger syndrome
– R to L atrial or ventricular
septal defect with pulmonary
stenosis.
o Occurs when:
Output of the RV is less than the
blood volume received by the RA
from the vena cava
Back-pressure results in:
– congestion of the systemic
venous circulation
– Decreased cardiac output to
the lungs
Bp decreases in the aorta
High pressure in the vena cava
Jugular venous distention
Increased portal circulation
– Liver & spleen become
LEFT-SIDE HEART FAILURE MED. MGT: distended
o If MV stenosis is present, thrombus Distention of abdominal vessels can
formation can occur from non-circulating lead to exudate of fluid from the
blood. vessels into the peritoneal cavity
Adm. Anticoagulant (ascites).
– Heparin (does not cross the
placenta) for early pregnancy
– Warfarin (Coumadin) can be used
after 12 wk. but returned to heparin
during the last month of pregnancy
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NCM 109: MATERNAL AND CHILD HEALTH NURSING
RIGHT-SIDE HEART FAILURE MED. MGT.: CLASSIFICATION OF HEART DISEASE
o Those with uncorrected anomaly of this o To predict a pregnancy outcome, heart
type (Eisenmenger syndrome) may be disease is divided into four categories
advised not to get pregnant. based on criteria established by the New
York Heart Association.
PERIPARTUM HEART DISEASE
CLASS DESCRIPTION
WOMAN WITH PERIPARTUM HEART DISEASE
PERIPARTAL CARDIOMYOPATHY Class 1 Uncompromised. Ordinary physical activity
o Can originate in pregnancy in women causes no discomfort. No symptoms of
with no previous history of heart disease cardiac insufficiency and no anginal pain.
(Desplantie, Tremblay-Gravel, Avram, et
al., 2015). Class 2 Slightly compromised. Ordinary physical
o Cause: unknown activity causes excessive fatigue,
o May occur because of the stress of the palpitation, and dyspnea or anginal pain.
pregnancy on the circulatory system.
o The mortality rate = 50%. Class 3 Markedly compromised. During less than
Signs and Symptoms ordinary activity, woman experiences
Shortness of breath excessive fatigue, palpitations, dyspnea, or
Chest pain anginal pain.
Nondependent edema
Class 4 Severely compromised. Woman is unable to
Her heart increases in size (i.e.,
carry out any physical activity without
cardiomegaly).
experiencing discomfort. Even at rest,
For Therapy: symptoms of cardiac insufficiency or
1. She must sharply reduce her physical anginal pain are present.
activity
2. Diuretic
3. An arrhythmia agent, and digitalis CARDIAC DISEASE
therapy to maintain heart function ASSESSMENT
4. Low–molecular-weight heparin may be
administered. 1. A thorough health history to document pre-
5. Immunosuppressive therapy pregnancy cardiac status.
(Corticosteroids) 2. Woman’s level of exercise performance.
o If the cardiomegaly persists past the 3. Ask if she normally has a cough or edema
postpartum period – Coughing could be a sign of pulmonary
– It is generally suggested a woman not edema.
to attempt any further pregnancies – The usual innocent edema of
because the condition tends to recur pregnancy must be distinguished from
or worsen in additional pregnancies. the beginning of edema from heart
– Oral contraceptives are failure (serious).
contraindicated because of the danger
of thromboembolism that these can
create.