DRUG STUDY inhibition of

Drug Order
Generic Name:
prostaglandin
Mefenamic acid synthesis;
exact
Brand Name:
Ponstel
Classification:
Nonsteroidal anti-inflammatory drug
mechanism
(NSAID)
Route:
of action are
PO not known
Dosage:
500 mg Anti-
Frequency:
q8 PRN for pain
inflammatory;
Mechanism of Action
analgesic,
Anti- and
inflammatory; antipyretic
analgesic, activities
and related to
antipyretic inhibition of
activities prostaglandin
related to synthesis;
exact
Respiratory: dyspnea, hemoptysis,
pharyngitis
Other: peripheral edema, anaphylactoid
mechanism reactions to anaphylactic schock

Nursing Considerations
of action are BEFORE:

not known 


Check Doctor’s order
Assess pain score
Assess for history of allergies to
Anti-inflammatory analgesic, and
antipyretic activities related to inhibition of NSAIDs
prostaglandin synthesis; exact mechanism  Educate patient regarding desired
of action are not known. and adverse effects
 Educate patient that prolonged use
Indications of drug may damage liver
General: DURING:
 Relief of moderate pain when  Give drug with food, milk or antacids
therapy will not exceed 1 week
 Do not increase or double the dose,
 Treatment of primary dysmenorrhea follow exactly as prescribed, and
Patient’s actual indications: indicated
 Administer drug with full glass of
 Mefenamic acid is given to patient water
for relief of acute to moderately  Do not administer drug with full
severe pain glass of water
 Do not break, crush or chew capsule
Contraindications and tablet
 Do not administer with
Contraindicated with hypersensitivity to anticoagulants and other drug that
mefenamic acid aspirin allergy, and as causes GI upset for non serious side
treatment of perioperative pain with effects
coronary artery bypass grafting
Drug Order
Generic Name:
Adverse effects
Paracetamol
CNS: headache, dizziness, insomia
Brand Name:
Dermatologic: rash, pruritos, sweating
Biogesic
GI: nausea, GI pain, diarrhea, constipation
Classification:
GU: dysuria, renal impairment
Anti-pyretic
Hematologic: bleeding, platelet inhibition
with higher doses, neutropenia Route:
PO/TIV
Dosage: Drug Order
450 mg Generic Name:
Frequency: Cephalexin
Q6 for 24 hrs Brand Name:
Mechanism of Action Keflex
Blocks pain impulses by inhibiting synthesis Classification:
of prostaglandin. It relieves fever by central
action in the hypothalmic heat-regulating  Antibiotic
center  Cephalosporin (first generation)

Indications Route:

Symptomatic relief of pain and fever PO

Contraindications
 Contraindicated in patients
hypersensitive to drug
 Use cautiously in patients with long
term alcohol use because therepeutic
doses hepatotoxicity in these
patients
Adverse Effects
Hematologic: hemolytic, anemia,
neutropenia, leucopenia, pancytopenia,
Hepatic: jaundice
Metabolic: hypoglycemia
Skin: rash, urticaria
Nursing Considerations
 Advice patient that drug is only for
short term use and to consult the
physician if giving to children for
longer than 5 days or adults for
longer than 10 days
 Advice patient or caregiver that
many over the counter products
contain acetaminophen; be aware of
this when calculating total daily dose
 Warn patient that high doses or
unsupervised long term use can
cause liver damage
Dosage:
500 mg
Frequency:
Q6 for 7 days
Mechanism of Action
Inhibits synthesis of bacterial cell wall,
causing cell death
Indications
 Respiratory tract infections
caused by streptoccocus
pneumonia, group A beta-
Hemolytic streptoccoci
 Skin and skin structure
infections caused by
staphyloccocus, streptococcus
 Otitis media caused by S.
pneumoniae, Haemophilus
influenzae , streptococcus,
staphylococcus, Moraxella
catarrhalis
 Bone infections caused by
staphylococcus, Proteus
mirabilis
 GU infections caused by
 Escherichia coli, P.mirabilis,
Klebsiella
Contraindications
 Contraindicated with allergy to
cephalosporins or penicillins.
 Use cautiously with renal failure,
lactation, pregnancy.
Adverse Effects
 This drug is prescribed for this
particular infection; do not self-treat
any other infection.
 You may experience these side
effects: Stomach upset, loss of
appetite, nausea (take drug with
food); diarrhea; headache, dizziness.

 CNS: Headache, dizziness, lethargy,

paresthesias
 GI: Nausea, vomiting, diarrhea,
anorexia, abdominal pain, flatulence,
pseudomembr anous colitis,
hepatotoxicity
 GU: Nephrotoxicity
 Hematologic: Bone marrow
depression
 Hypersensitivity: Ranging from rash
to fever to anaphylaxis;
serumsickness reaction
 Other: Superinfections

Nursing Considerations
Assessment

 History: Penicillin or cephalosporin

allergy, pregnancy, or lactation
 Physical: Renal function tests,
respiratory status, skin status;
culture and sensitivity tests
of infected area
Interventions
 Arrange for culture and sensitivity
tests of infection before and during
therapy if infection does not resolve.
 Give drug with meals; arrange for
small, frequent meals if GI
complications occur.
 Refrigerate suspension, discard after
14 days.
Teaching points
 Take this drug with food. Refrigerate
suspension; discard any drug after
14days.
 Complete the full course of this drug
even if you feel better.