The BlueDiver Instrument is an Integrated Platform

For The Automation of the Immunodot Assays.

Unique Features
> Space saving
As compact as a microwave oven

> No risk of contamination

No pumps, no liquid handling, no dead volume, works with ready to use and
disposable reagents cartridges

> Flexible
From 1 to 24 similar or different assays can be run simultaneously

> Easy to use

Simply load the Immunodot Strips, the reagent cartridges, the patient
samples, press on and follow the test processing data through a user friendly
touch screen

> Automatic check-in

Through a bar-code association between the strips and the reagent cartridges

> Unequalled short testing time

Thanks to an Innovative processing principle

> Open system

Compatible with the whole range of D-Tek’s Immunodot products and with a
large panel of other Immunoassays
 The BlueDiver Quantrix kits are composed of Immunodot
Strips on which the antigens are coated in a microarray
format. Each kit contains 24 strips and reagent cartridges
dedicated to the BlueDiver Instrument.

Unique Features
> Multiplexing of the parameters
Microarray format allows the simultaneous screening of up to 25 different
autoantibodies (i.e., the ANA-25 Quantrix Strips)

> Unequalled testing time

Only 45 minutes from the start to the results

> Automatic validation of the tests

Triplicate dots allow the automatic measurements of the intra-assay variations
and multiple built-in controls allows the automatic validation of the test (sample
loading, conjugate type and substrate kinetics)

> Full quantitative results

Calculated through a built-in 6 points calibrating curve, including blank measu-
rement

> Low Sample consuming

Only 10 µl of crude sample are needed, without any required predilution

> Easy access to the data

Easy measurement, edition and tracking of the patients data through the Dr DOT
Interpretation System

Product code
Strip number

2D Bar-Code
For automatic identification of the strips.

Sample Control
Nucléosome
dsDNA Appears if the strip is correctly incubated with the sample. Allows the reading
Histones
Sm system to get the correct positions of other spots.
RNP 68kD/A/C
Sm/RNP
SSA
Trim21
SSB
Scl-70
Ku
PM/Scl
Mi-2
Jo-1 Coated Antigens
PL-7
PL-12 Each antigen is coated in triple (1 antigen / line).
SRP
Ribosomes Depending on the test, the strip may contain variable number of antigens
CENP A/B (from 2 to 25). The results are quantified using the curve calculated from the 5
PCNA
Sp100 standard values.
gp210
M2 recombinant
M2 native
F-actin
Blank control

Calibration curve
Appears on each strip for quantification of the antigens. 5 standards (colour
IgG
IgM Conjugate Controls increasing with the concentration) are coated in triple (1 standard / line).
IgA .
Substrate Control
Sample Control For checking correct substrate activity.
 09 / 2011

AntiPhospholipid Syndrome
Autoimmune Hepatitis type 1
Autoimmune Hepatitis type 2
Celiac Disease
Churg Strauss' Syndrome
Congenital Heart Block
CREST Syndrome
Crohn’s Disease
Drug Induced Lupus
Goodpasture Syndrome
Microscopic Polyangiitis
Milk Intolerance
Neonatal Lupus Erythematosus
Pernicious Anemia
Polymyositis/Dermatomyositis
Polymyositis/Scleroderma overlap syndrome
Primary Biliary Cirrhosis
Sclerdoderma
Sharp Syndrome
Sjögren's Syndrome
Subacute Cutaneous Lupus Erythematosus
Systemic Lupus Erythematosus
Vasculitis
Wegener's Granulomatosis
BlueDiverQuantrix Kit / BlueDiverDot Kit
BCOADC-E2 MI3DIV
ß-lactoglobulin BSDIV
ß2-GPI APSGDIV
Cardiolipin/ß2-GPI APSGDIV ; LU6DIV
CENP-A/B ANA12DIV ; ANA12SDIV ; ANA10DIV ; ANA8DIV
dsDNA CHRDIV ; CT10DIV ; DNADIV ; LU6DIV
F-actin LISDIV ; LI7DIV
GBM ANCAGDIV ; GBDIV
gp210 LI7DIV
Histones CHRDIV ; CT10DIV ; CTDIV ; LU6DIV ; LUDIV ; NUHISDIV
IF IFDIV ; IFPCADIV
Jo-1 ANA12DIV ; ANA12SDIV ; ANA10DIV ; ANA8DIV ; CT10DIV ; CTD ; CY6DIV ; ENADIV ; NUENADIV ; PMS8DIV
Ku ANA12DIV ; ANA12SDIV ; ANA10DIV ; PMS8DIV
LC1 LI7DIV ; LIDIV ; LISDIV
LKM1 LI7DIV ; LID ; LISDIV
M2 CY6DIV ; LI7DIV ; LIDIV ; LISDIV ; MIDIV
Mannan ASCCDIV
Mi-2 ANA12SDIV ; PMS8DIV
MPO ANCADIV ; ANCAGDIV
Nucleosome CHRDIV ; CT10DIV ; CTDIV ; LU6DIV ; LUDIV ; NUDIV ; NUENADIV ; NUHISDIV
OGDC-E2 MI3DIV
PCA IFPCADIV
PCNA ANA12DIV ; ANA12SDIV ; ANA10DIV
PDC-E2 MI3DIV
PL-12 CY6DIV ; PMS8DIV
PL-7 CY6DIV ; PMS8DIV
PM/Scl ANA12DIV ; ANA12SDIV ; ANA10DIV ; ANA8DIV ; PMS8DIV
PR3 ANCADIV ; ANCAGDIV

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Ribosome P ANA12DIV ; LU6DIV ; LUDIV ; CY6DIV
RNP (68K / A / C) ANA12DIV ; ANA12SDIV
Scl-70 ANA12DIV ; ANA12SDIV ; ANA10DIV ; ANA8DIV ; CT10DIV ; CTDIV ; ENADIV ; NUENADIV ; PMS8DIV
SLA LI7DIV ; LISDIV
Sm ANA12DIV ; ANA12SDIV ; ANA10DIV ; ANA8DIV ; CT10DIV ; CTDIV ; ENADIV ; NUENADIV ; LU6DIV ; LUDIV
Sm/RNP ANA12DIV ; ANA12SDIV ; ANA10DIV ; ANA8DIV ; CT10DIV ; CTDIV ; ENADIV ; NUENADIV
Soya BSDIV
sp100 LI7DIV
SRP CY6DIV ; PMS8DIV
SSA (Ro) ANA12DIV ; ANA12SDIV ; ANA10DIV ; ANA8DIV ; CT10DIV ; CTDIV ; ENADIV ; NUENADIV

We Apply Science
www.d-tek.be
SSB (La) ANA12DIV ; ANA12SDIV ; ANA10DIV ; ANA8DIV ; CT10DIV ; CTDIV ; ENADIV ; NUENADIV
TRIM 21 CT10DIV