DRUG STUDY

Name of drug Classification Mechanism Indications Contraindicatio Adverse Nursing

of action n Effects Responsibilities
Generic Name: Therapeutic -NRTI that - HIV - CNS: Before:
Zidovudine Classification: Contraindicate asthenia, - assess for
inhibits infection, with contraindicatio
Antiretrovirals replication other d in patients dizziness,
ns to this
who have had fever, drug: any
of HIV by antiretrovirals
a potentially fatigue,hea history of
blocking dache,inso
Brand Name: life-threatening allergy to
DNA - to prevent mia, antivirals
hypersensitivity
synthesis material-fetal reaction to paresthesia - perform a
Retrovir ,somnolenc physical
transmission drug or its
e assessment
Pharmacologi of HIV components
GI: -assess level
c - potentially life of orientation
Dosage: Classification: anorexia,
threatening and reflexes
Nucleoside- hypersensitivity nausea, - examine the
reactions, such vomiting,pa skin (color,
nucleotide
as anaphylaxis ncreatitis, temperature,
Route:
reverse abdominal and lesions )
transcriptase and SJS, can
pain, - check
occur. temperature
inhibitors constipation
-Use -evaluate
, hepatic and
cautiously in
diarrhea,dy renal function
patients with
spepsia, tests
granulocyte
taste During:
count less than - monitor renal
prevention .
1000 and hepatic
Hematolog
cells/mm^3 or function
ic:
Hb level less before and
agranulocyt
than 9.5 g/dL periodically
osis,neutro during therapy
penia, -ensure that
severe the patients
bone takes the
marrow complete
suppressio course of the
n, drug regimen
and takes all
thrombocyt drugs
openia, included in a
anemia. particular
Hepatic: combination
altered LFT -administer
values, the drug
hepatomeg around the
clock,if
aly. indicated
Metabolic: - monitor
lactic nutritional
acidosis status if GI
Muscoskel effects are
etal: severe and
athralgia, take
myaglia,my appropriate
action
opathy. - stop drug if
Respiratory severe rash
: cough, occurs,especi
wheezing ally
 Skin: rash, After:
diaphoresis
--Monitor
patient
response to
the drug

-Monitor for
adverse
effects (level
of orientation
and affect, Gi
upset,renal
and hepatic
function, skin,
levels of blood
components

- evaluate the
effectiveness
of the
teaching plan
(patient can
name of the
drug,
dosage,possib
le adverse
effects to
watch for,and
specific
measures to
help avoid
adverse
effects)

- monitor the
effectiveness of
comfort and
safety
measures and
compliance
with the
regimen

Source: Kluwer, W. (2021). Nursing 2021 Drug Handbook.