DRUG STUDY

Name of drug Classification Mechanism Indications Contraindicatio Adverse Nursing

of action n Effects Responsibilities
Generic Name: Therapeutic -NRTI that - HIV -Contraindicated CNS: Before:
Zidovudine Classification: in patients who asthenia, - assess for
inhibits infection, with dizziness, contraindicatio
Antiretrovirals have had a
replication other potentially life- fever, ns to this
of HIV by antiretrovirals threatening fatigue,head drug: any
blocking hypersensitivity ache,insomia history of
Brand Name: , allergy to
DNA - to prevent reaction to drug
antivirals
or its paresthesia,
synthesis material-fetal somnolence - perform a
Retrovir components
transmission GI: anorexia, physical
Pharmacologi - potentially life assessment
c of HIV threatening nausea,
vomiting,pan -assess level
Classification: hypersensitivity of orientation
Dosage: creatitis,
Nucleoside- reactions, such and reflexes
as anaphylaxis abdominal
nucleotide pain,
- examine the
and SJS, can skin (color,
reverse occur. constipation,
temperature,
transcriptase diarrhea,dys
Route: -Use and lesions )
inhibitors pepsia, taste - check
cautiously in prevention . temperature
patients with Hematologi -evaluate
granulocyte c: hepatic and
count less than agranulocyto renal function
1000 sis,neutrope tests
cells/mm^3 or nia, severe During:
Hb level less bone marrow - monitor renal
suppression, and hepatic
than 9.5 g/dL
thrombocyto function
penia, before and
anemia. periodically
Hepatic: during therapy
altered LFT -ensure that
values, the patients
hepatomegal takes the
y. complete
Metabolic: course of the
lactic drug regimen
acidosis and takes all
Muscoskele drugs
tal: athralgia, included in a
myaglia,myo particular
pathy. combination
Respiratory: -administer
cough, the drug
wheezing around the
Skin: rash, clock,if
diaphoresis
indicated
- monitor
nutritional
status if GI
effects are
severe and
take
appropriate
action
- stop drug if
severe rash
occurs,especi
ally
 After:

--Monitor
patient
response to
the drug

-Monitor for
adverse
effects (level
of orientation
and affect, Gi
upset,renal
and hepatic
function, skin,
levels of blood
components

- evaluate the
effectiveness
of the
teaching plan
(patient can
name of the
drug,
dosage,possib
le adverse
effects to
watch for,and
specific
measures to
help avoid
adverse
effects)

- monitor the
effectiveness of
comfort and
safety
measures and
compliance
with the
regimen

Source: Kluwer, W. (2021). Nursing 2021 Drug Handbook.