1. What is/are the most abundant connective tissue cells present in the stroma?

- The fibroblast is one of the most abundant cell types present in the stroma. It has a
variety of functions and composes the basic framework for tissues and organs.
Fibroblasts also play a well-recognized role in the carcinogenic process. They
are responsible for synthesis, deposition and remodeling of much of the extracellular
matrix in tumour stroma, and they are recognized as a source of paracrine growth
factors that influence the growth of carcinoma cells. Fibroblasts secrete collagen
proteins that are used to maintain a structural framework for many tissues. They also
play an important role in healing wounds.

2. Enumerate and describe specific locations where dense lymphoid tissue is found. 

- The most highly organized lymphoid tissues are in the thymus and lymph nodes, which
are well-defined encapsulated organs with easily identifiable architectures. In the spleen
a soft, purplish organ lying high in the abdomen, the lymphoid tissue is a cylinder of
loosely organized cells surrounding small arteries. Lymphoid tissues are organized
structures that support immune responses. The bone marrow and thymus are primary
lymphoid tissues and the sites of lymphocyte development. They create special immune
system cells called lymphocytes, while the secondary lymphoid organs these organs
include the lymph nodes, the spleen, the tonsils and certain tissue in various mucous
membrane layers in the body.

3. Describe the cells that predominate in the lymphatic cord. 

- Lymph nodes are a confluence of adjacent lymphoid units that typically consist of a
follicle in which B cells predominate and deep cortical units DCU, in which T cells
predominate. Lymph, containing micro-organisms, soluble antigens, antigen presenting
cells, and a few B-cells, enters the lymph node via afferent lymphatic vessels which
enter the subcapsular sinus. It then runs through cortical sinuses into medullary
sinuses and leaves through the efferent lymphatic vessels, at
the hilium as efferent lymph. This contains lots of T-lymphocytes, B-lymphocytes,
plasma cells and antibody. The cortex is divided into an outer and an inner cortex.
The outer cortex has lymphatic nodules that mostly contain B-cells. Small lymphocytes
sit in the spaces between the reticular fibre meshwork in the cortex while The inner
cortex contains mostly T-cells
Question#1

https://www.frontiersin.org/articles/10.3389/fphar.2014.00123/full

https://www.ncbi.nlm.nih.gov/books/NBK541065/#:~:text=The%20fibroblast%20is%20one
%20of,framework%20for%20tissues%20and%20organs.

Question #2

https://www.britannica.com/science/lymphoid-tissue

https://www.nature.com/subjects/lymphoid-tissues

Question #3

https://www.aacc.org/science-and-research/clinical-chemistry-trainee-council/trainee-
council-in-english/pearls-of-laboratory-medicine/2015/lymph-node-structure-and-
function#:~:text=The%20lymph%20node%20can%20be,the%20paracortex%2C%20T
%20cells%20predominate

https://www.sciencedirect.com/topics/neuroscience/lymph-node

http://medcell.med.yale.edu/systems_cell_biology/lymphatics_lab.php

https://courses.lumenlearning.com/boundless-ap/chapter/lymph-cells-and-tissues/
#:~:text=Lymph%20nodes%20are%20repositories%20of,adaptive%20immune
%20responses%20are%20triggered.

Name of contributor:
Dimaculangan, Yumie F.