GENE FAMILIES

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GENE CLUSTERS
Gene cluster size varies from a few genes to several 100 genes.

TANDEM REPEATS

PSEUDO GENES
EXAMPLES OF GENE FAMILIES

GLOBIN GENES
REPRESENTATION OF EVOLUTION OF ANCESTRAL GLOBIN
GENES
1) HAEMOGLOBIN GENES
 VARIOUS GLOBIN GENES

HUMAN HAEMOGLOBIN GENE CLUSTERS, WITH THE ALPHA

AND BETA CHAINS
2) MYOGLOBIN GENES
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ROLE OF MYOGLOBIN IN DISEASE

DIAGRAM REPRESENTING THE POSITION OF MYOGLOBIN

GENE ON THE CHROMOSOME
 3) LEG HAEMOGLOBIN

- Leg haemoglobin is a monomeric protein that contains a single polypeptide chain

which is bind with hame
- Mol.weight is 16 K Dalton
- It is synthesized from leguminous plants in association with rhizobia
- These proteins binds with 02 and enhance the N2 fixation by bacterium

EVOLUTION – MULTI GENE FAMILIES

The multi gene families evolve through

- DUPLICATION
- CONCERTED EVOLUTION

DUPLICATION
CONCERTED EVOLUTION