Federal State Budgetary Educational Institution of Higher Education

«Bashkir State Medical University»

Ministry of Health of the Russian Federation

The department of Pharmacology № 1 with a course of clinical

pharmacology

APPROVE

Head of department Alekhin E.K.

" 28 " June 2018

METHODICAL RECOMMENDATION
FOR STUDENTS
for a practical lesson on the topic
«INTRODUCTION TO THE PRESCRIPTIONS. THE PRESCRIPTIONS AND
ITS STRUCTURE, THE RULES FOR WRITING IT OUT. DOSES.
PHARMACOPOEIA. CLASSIFICATION OF MEDICINAL FORMS. HARD
AND SOFT DOSAGE FORMS».

Discipline pharmacology
Specialty 31.05.03-Dentistry
Course II
Semester III-IV

Ufa
2018
Topic: Introduction to the prescriptions. The prescriptions and its structure, the
rules for writing it out. Doses. Pharmacopoeia. Classification of medicinal
forms. Solid and soft dosage forms based on the work program of the discipline
"Pharmacology" in the field of dentistry 31.05.03 (full-time training), approved
by " 28 " June 2018.

Reviewers:
1) head of the Department of General and clinical pharmacology OF the
Russian Ministry of health, Ph. D., Professor A. L. Urakov
2) Head of the Department of pharmacology named after Professor A. A.
Lebedev, Ph. D., associate Professor E. N. Zaitseva

Author:
Mufazalova N.A.
Khayrzamanova K.A.

Approval at session №1 of the Department of pharmacology №1 with the

course of clinical pharmacology from August 31, 2018.
 1.Topic: GENERAL PRESCRIPTIONS. THE GENERAL RULES OF
PRESCRIPTION. SOLID DOSAGE FORMS
Medicines are used to treat patients in all areas of medicine, and many of
them are given to patients according to prescriptions. Therefore, the development
of prescription issues is an integral part of the preparation of a doctor.
2. Lesson purpose: mastering the medical skills of diagnosis and treatment
of patients with a dental profile, the ability to provide emergency care, to prevent
complications.
Students must know to build the skill.:
- What is a prescriptions and its components
- Prescription forms and orders confirming the forms of prescription forms and
rules for the design of prescriptionss.
- General rules for prescribing prescriptions
- Classification of dosage forms
- The value of the individual ingredients included in the drug.
- Properties of hard and soft dosage forms.
- Rules for prescribing hard and soft dosage forms.
- Storage rules for poisonous, potent and narcotic substances in pharmacies and
medical institutions and especially the prescription of them.
As a result of mastering the topic of the lesson, students should own and be
able to:
- Write prescriptions for solid (powders, metered and undosed, powders,
tablets, dragees, granules) and soft (ointments, pastes, liniment,
suppositories) dosage forms.
- Write prescriptions for soft dosage forms (ointments, pastes, liniment,
suppositories).
- and master the following competencies
OK-1-Ability to abstract thinking, analysis, synthesis;
OK-5-Willingness to self-development, self-realization, self-education,
the use of creative potential
OPK-7- Willingness to use the basic physico-chemical, mathematical and
other natural science concepts and methods in solving professional
problems
OPK-8- Preparedness for medical use of drugs and other substances and
their combinations in solving professional problems

3. Necessary basic knowledge and skills:

the content of pharmacology, its tasks and position among other medical
disciplines;
 to study the rules for writing prescriptions based on order No. 1175 of
12/20/12;
dosology (dose classification by effect and frequency
the concept of dosage forms, their types;
characterization of certain types of hard and soft dosage forms and the rules
for prescribing them.
features of absorption of drugs for rectal administration, indications for use,
methods of prescribing;
4. Type of occupation: practical lesson.
5. Lesson duration:3 hours.
6. Equipment: table "Forms of prescription forms - No. 107-1 / у, No. 148-1 / у-88, 148-
04 (l), special form"
7. Lesson content
7.1 Organizational stage - checking the readiness of the group for the lesson,
appearance, marking those present, familiarization with the work plan
7.2 Control of the initial level of knowledge and skills using tests.
7.3 Familiarization of students with the content of the lesson. The presentation
of key issues of the topic of this lesson. Demonstration by the teacher of the
methodology of practical techniques on this topic. Theoretical analysis of
the topic. Poll.
7.4 Independent work of students under the supervision of a teacher (prescribing
prescriptions for this topic, answers to questions on pharmacotherapy).
7.5 Analysis of prescriptions for this topic and answers to questions on
pharmacotherapy (tablets, ointments, pastes, etc.)
7.6 Control over the assimilation by students of the topic of the lesson
(knowledge and skills) using test tasks, situational tasks and other types of
control.
 Lesson structure (routing)
No. p Time in Visual aids
/p Stages of the lesson and their content min. Purpose and nature of the action

Student Teacher
1 2 3 4 5 6

7.1.
Checks the readiness of
Organizational stage. Checking the readiness
the group for the lesson,
of the group for the lesson, appearance, Getting to know the work
5 appearance, notes those
marking those present, familiarization with plan
present, introduces the
the work plan
plan работы
7.2.

Monitoring the initial level of knowledge of The solution of typical Controls the process of
15
students using tests. problems using test tasks. completing test tasks
7.3. Introducing students to the content of classes.
Presentation of nodal
questions in this lesson. Teacher demonstration
practical techniques on the subject. Theoretical
analysis of the topic. Poll.
1. What is a prescriptions and its components
2. Prescription forms and orders confirming
the forms of prescription forms and rules
for the design of prescriptionss.
3. General rules for prescribing.
4. Classification of dosage forms.
5. The value of the individual ingredients
Assesses the level of
included in the drug. Answers theoretical
45 Tables, Demonstration Slides theoretical knowledge
6. Properties of hard and soft dosage forms. questions,
of the student.
7. Rules for prescribing hard and soft dosage
forms.
8. The rules for the storage of toxic, potent
and narcotic substances in pharmacies and
medical institutions and especially the
prescription of them.

7.4
Supervises the process
Independent work of students under the
Prescribes, answers of prescribing and
supervision of a teacher (prescribing
30 Drugs on this topic pharmacotherapy answering
prescriptions for this topic, answers to
questions pharmacotherapy
questions on pharmacotherapy)
questions
 Demonstrates prescription
Estimates the level of
Analysis of prescriptions for this topic and methods and answers to
7.5. 20 Drugs on this topic mastery of prescribing
answers to questions on pharmacotherapy pharmacotherapy
skills on this topic.
questions.

Monitoring the assimilation by students of the

Answers test tasks in a Evaluates test results
topic of the lesson (knowledge and skills) Vagant computer program,
7.6 20 computer class, solves and the theoretical stage
using test tasks, situational tasks and other situational tasks
situational tasks of the final task
types of control.
 Control of the initial level of knowledge and skills
Choose the right answers.
1. What is the minimum weight of the dosed powder?
a) 0,007;
b) 0,1;
c) 0,005;
d) 0,01;
e) 0,5;
f) 0,7;
g) 1,1;
h) 1,0.
2. What is the maximum mass of the dosed powder?
a) 0,12;
b) 0,4;
c) 0,05;
d) 0,1;
e) 1,0;
f) 2,0;
g) 2,5.
3. What properties should form-forming substances have for solid dosage forms?
a) be able to interact with medicinal substances chemically;
b) be able to interact with medicinal substances physically;
c) be indifferent to drugs;
d) be indifferent to the human body;
e) be hygroscopic;
f) be loose.
4. What can serve as a forming substance for a dosed powder?
a) sugar ;
b) spirit;
c) talc;
d) dextrose (glucose);
e) petroleum jelly;
f) metamizole sodium (analgin).
5. What can serve as a shaping agent for powders?
a) sugar;
b) starch;
c) talc;
d) dextrose (glucose);
e) cocoa butter;
f) petrolatum.

Choose the right answers.

6. Indicate the most hygroscopic ointment base.
a) petrolatum;
 b) lanolin;
c) naphthalan ointment;
d) spermaceti;
e) eugenol
7. What can serve as a forming substance for the preparation of candles?
a) sugar;
b) sodium bicarbonate;
c) glycerin;
d) petrolatum;
e) cocoa butter;
f) spermaceti;
g) butyrol;
h) lanolin.
8. Indicate the maximum and minimum weight of rectal suppositories:
a) 8,0;
b) 7,0;
c) 6,0;
d) 4,0;
e) 3,0;
f) 2,0;
g) 1,1;
h) 1,0;
9. Indicate the maximum and minimum weight of vaginal suppositories:
a) 8,0;
b) 7,0;
c) 6,0;
d) 5,0;
e) 4,0;
f) 3,0;
g) 2,0;
h) 1,5
10.How many powdered substances does dental paste contain?
a) 100%;
b) 75%;
c) 60%;
d) 25%;
e) 15%;
f) 5%.

Answer the following questions:

1. How much zinc oxide should I take to make 20.0 10% powder?
2. How much and what formative substance do I need to take to prepare 40.0
powders containing 5% benzocaine (anestezin)?
 3. How much and what formative substance you need to take to prepare: one
drotaverine powder, a single dose of 0.04; 30 drotaverine powders, single
dose 0.04.
4. How much do you need to take streptocide (Streptocidum) for the
preparation of 15.0 10% ointment?
5. How much petroleum jelly does it take to prepare 40.0 ointments containing
10% salicylic acid (Acidum salicylicum)?
6. How much do I need to take lanolin (Lanolinum) and petroleum jelly
(Vaselinum) (equally) for the preparation of 20.0 ointments with 10%
xeroform (Xeroformium)?
7. How much benzocaine (anesthesin) (Benzocaine) should I take to prepare
50.0% ointment?

Independent work of students under the supervision of a teacher

1. Laboratory work.
To get acquainted with different solid and dosage forms, excipients and
corrective substances for solid dosage forms, types of capsules, with various
soft dosage forms, excipients.
2. Write out the prescriptionss:

Option 1
1. 40 powders of cephalexin (Cefalexinum), 0.5 in gelatin capsules. Assign 1
capsule 4 times a day.
2. 20 powders of methyluracil (Methyluracilum) at 0.5. Prescribe by mouth 1
powder 4 times a day after meals.
3. 20.0 minute powder, consisting of 50% streptocidum (Streptocidum) and 50%
silver sulfathiazole (Sulfathiazole silver), for blowing into the nose.
4. Nitroglycerin (Nitroglycerinum) in tablets of 0.0005, appoint 1 tablet under the
tongue for pain in the heart.
5. 30 tablets containing folic acid (Acidum folicum) 0.0008 and ascorbic acid
(Acidum ascorbinicum) 0.1. Assign inside 1 tablet 2 times a day.
6. 10 rectal suppositories “Neo-Anusolum” (Neo-anusolum). Assign 1 suppository
to the rectum 2 times a day.
7. 10.0 ointments containing 0.25% oxolin (Oxolinum). Assign 3 times a day to
lubricate the nasal mucosa.
8. 30.0 paste containing 5% zinc oxide (Zinci oxydum). Assign for application to
the affected area.
9. Liniment containing 10% chloramphenicol (Chloramphenicol) in an amount of
40.0.
10.10 Prescribe 15 grams of paste for devitalization of pulp containing 10%
arsenic acid (Acidum arsenicosum anhydricum) 40% thymol (Timolum), as an
ointment base glycerin (Glycerinum).
 Option 2
1. 100 powders of aminosalicylic acid (sodium paraaminosalicylate)
(Aminosalicylic acid), 1.0 each. Assign inward 3 powders 3 times a day.
2. 30 powders of rifampicin (Rifampicinum) at 0.3 in gelatin capsules. Assign
inside 1 capsule 3 times a day half an hour before meals.
3. A powder containing 30% zinc oxide (Zinci oxydum), 50% talc (Talcum) and
20% starch (Amylum).
4. Isosorbide dinitrate (Isosorbide dinitrate) in tablets of 0.02. Assign 1 tablet
orally 3 times daily before meals.
5. 40 tablets containing 0.05 each of ascorbic acid (Ac.ascorbinicum) and rutoside
(rutin) (Rutoside), 0.2 dextrose (glucose (Dexstrose). Assign 1 tablet 3 times a
day by mouth.
6. 10 vaginal suppositories containing 0.05 trichomonacid (Trichomonacidum).
Prescribe 1 candle 2 times a day.
7. 20 rectal suppositories “Betiolum” (Bethiolum). Assign 1 candle 2 times a day.
8. Write out 40 grams of 0.5% neomycin ointment (Neomycin) for external use.
9. 50.0 liniment in castor oil (Oleum Ricini), containing 5% xeroform
(Xeroformium) and vinylin (Vinylinum), for application to affected skin.
10. 30.0 pastes with 20% zinc oxide (Zinci oxydum). Assign for application to
affected skin.
Option 3
1. 6 powders of phenobarbital (Fhenobarbitalum) at 0.1. Assign 1 powder inside
one hour before bedtime.
2. 10 complex powders consisting of papaverine hydrochloride (Papaverini
hydrchloridum) - a single dose of 0.02, and platyphylline hydrotartrate
(Platyphyllini hydrotartras) - a single dose of 0.005, in waxed paper. Prescribe 1
powder 3 times a day.
3. 100.0 Urodani (Urodanum). Assign 1 teaspoon of the powder inside in 1/2 cup
of water.
4. Powder consisting of 5% bismuth subgallate (dermatol) (Bismuth subgallate)
and 25% zinc oxide (Zinci oxydum).
5. Ciprofloxacin (Ciprofloxacin) in tablets of 0.25. Assign inside 1 tablet 2 times a
day.
6. 10 rectal suppositories with methyluracil (Methyluracilum) at 0.5. Assign 1
candle 3 times a day.
7. Write out 30.0 grams of tricrizol-formalin paste containing 20% tricrizol
(Tricresolum) and 5% formalin (Formalinum) to cover the pulp after amputation.
White clay (Bolus alba) and glycerin (Glycerinum) are recommended as forming
substances.
8. 25.0 ointments containing 10% streptocidum (Streptocidum) for application to
affected skin.
9. 50.0 ointments containing 10% birch tar (Pix liquidae) and precipitated sulfur
(Sulfur praecipitatum).
10. 100.0 paste containing 2% salicylic acid (Acidum salicylicum), up to 25% zinc
oxide (Zinci oxydum) and starch (Amylum) and petroleum jelly (Vaselinum)
(Lassara Pasta).
Option 4
1. 40 powders of ampicillin trihydrate (Ampicillini trihydras) 0.25 in gelatin
capsules. Assign 2 capsules 4 times a day.
2. 30.0 magnesium sulfate (Magnii sulfas). Assign inside once in ½ cup of water.
3. 50.0 powders containing 1% boric acid (Acidum boricum) and 20% zinc oxide
(Zinci oxydum).
4. Diclofenac (orthophene) (Diclofenac) in tablets of 0.025. Prescribe 1 tablet 3
times a day with meals or immediately after.
5. Dragees containing 0.1 mebhydrolin (diazolin) (Mebhydrolin). Assign 1 tablet
2 times a day.
6. 20 rectal suppositories containing 0.00015 digitoxin (Digitoxinum). Apply 2
times a day for 1 suppository.
7. 25.0 grams of officinal white mercury ointment (Ung. Hydrargyri album).
8. 30.0 ointments with 3% tetracycline (Telracyclinum). Assign for application to
affected skin.
9. 50.0 ointments containing 5% resorcinol (resorcinol) (Resorcinole) and 5%
salicylic acid (Acidum salicylicum).
10. 40.0 paste containing 1 part boric acid (Acidum boicum), 3 parts zinc oxide
(Zinci oxydum) and starch (Amylum), and 9 parts naphthalan ointment (Ung.
Naphthalani).

Option 5
1. 10 powders of diphenhydramine (diphenhydramine) (Diphenhydramine) at
0.05. Prescribe 1 powder 2 times a day.
2. Sodium sulfate (Natrii sulfas) 30.0. Assign inside once in ½ cup of water.
3. 50.0 minute powder containing 2% boric acid (Acidum boricum) and 5%
salicylic acid (Acidum salicylicum). Assign as a powder.
4. Enalapril (Enalapril) in tablets of 0.005. Assign inside 1 tablet 2 times a day.
5. 50 tablets “Allochol” (Allocholum). Prescribe 2 tablets orally 3 times a day
after meals.
6. 10 rectal suppositories containing zinc oxide (Zinci oxydum) 0.2, bismuth
subnitrate (Bismuthi subnitras) 0.075, tannin (Tanninum) 0.05. Prescribe 1
suppository 3 times a day rectally.
7. 20 vaginal suppositories containing 0.12 of aminitrozole (nitazole)
(Aminitrozole). Assign 1 candle to the vagina at night.
8. 30.0 ointments containing 0.5% dequalinium chloride (decamine) (Dequalinium
chloride). Assign for application to the affected areas of the mucosa.
9.100.0 ointments on lanolin containing 10% ichthyol (Ichthyolum), 6% salicylic
acid (Acidum salicylicum), 10% turpentine oil (Oleum Terebinthinae). Assign to
rub the skin in the area of the diseased joint.
10. 25.0 paste containing boric acid (Acidum boricum) 1 part, zinc oxide (Zinci
oxydum) and starch (Amylum) in 5 parts, and naphthalan ointment (Ung.
Naphthalani) 9 parts.
Control of mastering the topic of the lesson
It is held at the final lesson: students write out various solid dosage forms (5
ticket options for 10 questions) and answer the teacher's questions.
 Literature
Main literature

Year, place Number of copies

№ the of
Nomination
Аuthors publication in at the department
library
1 2 3 4 5 2

Kharkevich D.A.
Kharkevich D.A. Pharmacology: a Pharmacology: a
Kharkevich, 2015 810
1. textbook for high schools / D.A. textbook for high schools
accesses
Kharkevich. 8th ed., M: GEOTAR- D. A / D.A. Kharkevich. 8th
Media, 2015.720s ed., M: GEOTAR-Media,
2015.720s
D.A. Kharkevich
"Fundamentals of
D.A. Kharkevich "Fundamentals of
Pharmacology"
Pharmacology" [Electronic
[Electronic resource]: a
resource]: a textbook for high Kharkevich, 2015 500
2. textbook for high schools
schools / D.A. Kharkevich. 2nd ed., D. A accesses
/ D.A. Kharkevich. 2nd
Rev. and add. M: GEOTAR Media,
ed., Rev. and add. M:
2015.720s.
GEOTAR Media,
2015.720s.
D.A. Kharkevich
D.A. Kharkevich "Pharmacology" "Pharmacology" textbook
textbook [Electronic resource]: [Electronic resource]:
Kharkevich, 2015 500
3. D.A. Kharkevich. 11th ed., Rev. D.A. Kharkevich. 11th
D. A accesses
and add. M: GEOTAR-media, ed., Rev. and add. M:
2015.760s. GEOTAR-media,
2015.760s.

R.N. Aliautdin
R.N. Aliautdin "Pharmacology" "Pharmacology" textbook
textbook [Electronic resource]: for [Electronic resource]: for
R.N. 2015 500
4. universities /R.N. Alautdin. 5th ed., universities /R.N.
Aliautdin accesses Alautdin. 5th ed., Rev.
Rev. and add. M: GEOTAR Media,
2015.1104s. and add. M: GEOTAR
Media, 2015.1104s.
 Аdditional literature

Number of copies
№
Аdditional literature
in library at the department
1 500
Pharmacology: a guide to the lab. occupations Pharmacology: a guide to
[Electronic resource]: textbook / ed. YES. the lab. occupations
Kharkevich. 5th ed. M. GEOTAR-Media, 2012.488 s [Electronic resource]:
textbook / ed. YES.
Kharkevich. 5th ed. M.
GEOTAR-Media, 2012.488 s
2 Test tasks in pharmacology: a training manual / 500 Test tasks in
D.A. Kharkevich., E. Yu. Lemina., L. A. pharmacology: a training
Ovsyannikova., And others; 3rd ed., Rev. and manual / D.A. Kharkevich.,
additional - M.: GEOTAR-Media, 2013-352s. E. Yu. Lemina., L. A.
Ovsyannikova., And others;
3rd ed., Rev. and additional -
M.: GEOTAR-Media, 2013-
352s.
3 Clinical pharmacology and pharmacotherapy in 500 Clinical pharmacology and
real medical practice: master class [Electronic pharmacotherapy in real
resource]: textbook / V. I. Petrov. - M.: GEOTAR- medical practice: master
Media, 2014 .-- 880 p. : ill. class [Electronic resource]:
textbook / V. I. Petrov. - M.:
GEOTAR-Media, 2014 .--
880 p. : ill.

Signature of the author of the methodological development

" 28 " June 2018