Decoquinate

CHEMICAL NAME: Ethyl 6-(decyloxy)-7-ethoxy-4-hydroxy-3-quinoline carboxylate

Chickens
1. FDA Status: No feed mill license required.
Regulation §558.195
WARNING STATEMENT REQUIRED: Do not feed to laying hens producing eggs for human consumption.
CAUTION: Do not use Decoquinate in feeds containing bentonite.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Decoquinate 27.2 g/ton For the prevention of coccidiosis
caused by Eimeria tenella, Eimeria
necatrix, Eimeria acervulina, Eimeria
mivati, Eimeria maxima and Eimeria
brunetti.
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COMBINATIONS ALLOWED
2. FDA Status: No feed mill license required.
Regulations §558.195
WARNING STATEMENT REQUIRED: Do not feed to laying chickens.
CAUTION: Do not use Decoquinate in feeds containing bentonite.
LIMITATIONS FOR USE: Feed continuously as sole ration.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Decoquinate 27.2 g/ton For the prevention of coccidiosis
and caused by Eimeria tenella, Eimeria
necatrix, Eimeria acervulina, Eimeria
mivati, Eimeria maxima and Eimeria
brunetti.
Bacitracin 4-50 g/ton For increased rate of weight gain and
Methylenedisalicylate improved feed efficiency.
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3. FDA Status: No feed mill license required.

Regulation §558.195
WARNING STATEMENT REQUIRED: Do not feed to chickens producing eggs for human consumption.
CAUTION: Do not use Decoquinate in feeds containing bentonite.
LIMITATIONS FOR USE: Feed continuously for 7 to 14 days.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Decoquinate 27.2 g/ton For the prevention of coccidiosis
and caused by Eimeria tenella, Eimeria
necatrix, Eimeria acervulina, Eimeria
mivati, Eimeria maxima and Eimeria
brunetti.
Chlortetracycline 100-200 g/ton Control of infectious synovitis
caused by Mycoplasma synoviae
susceptible to Chlortetracycline.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Decoquinate 27.2 g/ton For the prevention of coccidiosis
and caused by Eimeria tenella, Eimeria
necatrix, Eimeria acervulina, Eimeria
mivati, Eimeria maxima and Eimeria
brunetti.
Chlortetracycline 200-400 g/ton Control of chronic respiratory disease
(CRD) and air sac infection caused by
Mycoplasma gallisepticum and
Escherichia coli susceptible to
Chlortetracycline.
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Decoquinate (Continued)
4. FDA Status: No feed mill license required.
Regulation §558.325
WARNING STATEMENT REQUIRED: Do not feed to laying hens producing eggs for human consumption.
CAUTION STATEMENT REQUIRED: Not for use in laying hens, breeding chickens or turkeys. Do not allow rabbits,
hamsters, guinea pigs, horses or ruminants access to feeds containing Lincomycin. Ingestion
by these species may result in severe gastrointestinal effects.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Decoquinate 27.2 g/ton For the prevention of coccidiosis caused
and by Eimeria tenella, Eimeria necatrix,
Eimeria acervulina, Eimeria maxima,
Eimeria mivati and Eimeria brunetti.
Lincomycin 2 g/ton For control of necrotic enteritis caused
or complicated by Clostridium spp., or
other organisms susceptible to Lincomycin.
LIMITATIONS: Feed as sole ration to broiler chickens. Do not use in feeds containing bentonite.
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Cattle
5. FDA Status: No feed mill license required.
Regulation §558.195
WARNING STATEMENT REQUIRED: Do not feed to cows producing milk for human consumption.
CAUTION: Do not use Decoquinate in feeds containing bentonite.
LIMITATIONS FOR USE: Feed for at least 28 days during periods of coccidiosis exposure or when experience indi-
cates that coccidiosis is likely to be a hazard. Type C feed may be prepared from dry or liquid
Type B feed containing 0.0125-0.5% Decoquinate. Type C cattle feeds may be manufactured
from Decoquinate liquid Type B feeds having a pH between 5.0 and 6.5 and containing a sus-
pending agent to maintain a viscosity of not less than 500 centipoises.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Cattle (including Decoquinate 12.9-90.8 g/ton For the prevention of coccidiosis
ruminating and non- caused by Eimeria bovis and Eimeria
ruminating calves and zuernii.
veal calves)
LIMITATIONS FOR USE: Feed Type C feed or milk replacer at a rate to provide 22.7 mg per 100 lb. of
bodyweight (0.5 mg/kg) per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Decoquinate 90.9-535.7 g/ton For the prevention of coccidiosis caused
by Eimeria bovis and Eimeria zuernii.
LIMITATIONS FOR USE: Feed Type C medicated feed supplements as a top dress or mix into the daily
ration at a rate to provide 22.7 mg per 100 lb. of bodyweight (0.5 mg/kg) per day.
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182 Additive Listings | 2021 Feed Additive Compendium

COMBINATIONS ALLOWED
6. FDA Status: No feed mill license required.
Regulation §558.195
WARNING STATEMENT REQUIRED: Do not feed to animals producing milk for food. A withdrawal period has not been
established for this product in pre-ruminating calves. Do not feed to calves to be processed for
veal. Withdraw 24 hours prior to slaughter when manufactured from ChlorMax Type A medicated
articles and Pennchlor Type A medicated Articles. Zero withdrawal time when manufactured from
Aureomycin Type A medicated articles manufactured by NADA sponsor No. 054771 (Zoetis) and
Deracin Type A medicated articles manufactured by ANADA sponsor No. 069254 (Pharmgate
Animal Health).
CAUTION: Do not use Decoquinate in feeds containing bentonite.
LIMITATIONS FOR USE: Feed Type C feed at a rate to provide 22.7 mg Decoquinate and 1 g Chlortetracycline per 100
lb. of bodyweight (0.5 mg/kg) per day for not more than 5 days. When consumed, feed 22.7 mg
Decoquinate per 100 lb. bodyweight per day for total of 28 days to prevent coccidiosis. Type C
feed may be prepared from dry or liquid Type B feed containing 0.0125-0.5% Decoquinate. Type
C cattle feeds may be manufactured from Decoquinate liquid Type B feeds having a pH between
5.0 and 6.5 and containing a suspending agent to maintain a viscosity of not less than 500
centipoises.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Calves, beef Decoquinate 12.9-90.8 g/ton For prevention of coccidiosis caused by
and nonlactating and Eimeria bovis and Eimeria zuernii.
dairy cattle Chlortetracycline 500-4,000 g/ton For treatment of bacterial enteritis caused
by Escherichia coli and for treatment of
bacterial pneumonia caused by Pasteurella
multocida organisms susceptible to
Chlortetracycline.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Decoquinate 90.9-535.7 g/ton For prevention of coccidiosis caused by
and Eimeria bovis and Eimeria zuernii.
Chlortetracycline 4,000-20,000 g/ton For treatment of bacterial enteritis caused
by Escherichia coli and for treatment of
bacterial pneumonia caused by Pasteurella
multocida organisms susceptible to
Chlortetracycline.
LIMITATIONS FOR USE: Feed Type C medicated feed supplements as a top dress or mix into daily ration
to provide 22.7 mg Decoquinate and 1 g Chlortetracycline per 100 lb. bodyweight per day for not more than
5 days.
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2021 Feed Additive Compendium | Additive Listings 183

Decoquinate (Continued)
7. FDA Status: No feed mill license required.
Regulations §558.195 and §558.355
WARNING STATEMENT REQUIRED: Do not feed to animals producing milk for food. Do not feed to lactating dairy
cows. A withdrawal time has not been established for pre-ruminating calves. Do not use in
calves to be processed for veal.
CAUTION: Do not use Decoquinate in feeds containing bentonite. Do not allow horses or other equines access to
feed containing Monensin. Ingestion of Monensin by equines has been fatal. Monensin-med-
icated cattle and goat feeds are safe for cattle and goats only. Consumption by unapproved
species may result in toxic reactions. Do not feed undiluted. Feeding undiluted or mixing er-
rors resulting in high concentrations of Monensin has been fatal to cattle. Must be thoroughly
mixed in feeds before use. Do not exceed the levels of Monensin recommended in the feeding
directions, as reduced average daily gains may result.
LIMITATIONS FOR USE: Feed continuously as the sole ration to provide 22.7 mg Decoquinate per 100 lb. of body-
weight (0.5 mg/kg) per day and 50-360 mg Monensin per head per day. Feed for at least 28
days during periods of coccidiosis exposure or when it is likely to be a hazard. Type C feed may
be prepared from dry or liquid Type B feed containing 0.0125-0.5% Decoquinate. Type C cattle
feeds may be manufactured from Decoquinate liquid Type B feeds having a pH between 5.0 and
6.5 and containing a suspending agent to maintain a viscosity of not less than 500 centipoises.
LIMITATIONS FOR LIQUID FEEDS: Liquid Type B feeds must be maintained at pH 5.0-6.5. Recirculate or agitate imme-
diately prior to use for not less than 10 minutes, moving not less than 1% of the tank contents
per minute from the bottom of the tank to the top or creating a turbulence at the bottom of the
tank that is visible at the top. Recirculate daily as described, even when not in use. Liquid Type
B feeds shall bear an expiration date of 8 weeks after its date of manufacture.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Cattle (fed in Decoquinate 12.9-90.8 g/ton* For the prevention of coccidiosis caused
confinement for and by Eimeria bovis and Eimeria zuernii.
slaughter) Monensin 5-30 g/ton* to provide For improved feed efficiency in cattle
50-360 mg/head/day being fed in confinement for slaughter.
*90% dry-matter basis
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184 Additive Listings | 2021 Feed Additive Compendium

8. FDA Status: No feed mill license required.
Regulations §558.195, §558.355 and §558.625
WARNING STATEMENT REQUIRED: Do not feed to animals producing milk for human food. A withdrawal time has
not been established for pre-ruminating calves. Do not use in calves to be processed for veal.
CAUTION: Do not use Decoquinate in feeds containing bentonite. Do not allow horses or other equines access
to feed containing Monensin. Ingestion of Monensin by equines has been fatal. Monensin-
medicated cattle and goat feeds are safe for use in cattle and goats only. Consumption by
unapproved species may result in toxic reactions. Do not feed undiluted. Feeding undiluted or
mixing errors resulting in high concentrations of Monensin has been fatal to cattle. Must be
thoroughly mixed in feeds before use. Do not exceed the levels of Monensin recommended in
the feeding directions, as reduced average daily gains may result.
LIMITATIONS FOR USE: Feed continuously as the sole ration to provide 22.7 mg Decoquinate per 100 lb. of body-
weight (0.5 mg/kg) per day, 50-360 mg Monensin per head per day and 60-90 mg Tylosin per
head per day. Feed for at least 28 days during periods of coccidiosis exposure or when it is
likely to be a hazard. Type C feed may be prepared from dry or liquid Type B feed containing
0.0125-0.5% Decoquinate. Type C cattle feeds may be manufactured from Decoquinate liquid
Type B feeds having a pH between 5.0 and 6.5 and containing a suspending agent to maintain
a viscosity of not less than 500 centipoises.
LIMITATIONS FOR LIQUID FEEDS: Liquid Type B feeds must be maintained at pH 4.5-6.0. Recirculate or agitate imme-
diately prior to use for not less than 10 minutes, moving not less than 1% of the tank contents
per minute from the bottom of the tank to the top or creating a turbulence at the bottom of the
tank that is visible at the top. Recirculate daily as described, even when not in use. Liquid Type
B feeds shall bear an expiration date of 31 days after its date of manufacture.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Cattle (fed in Decoquinate 13.6-27.2 g/ton* For the prevention of coccidiosis caused by
confinement for and (0.0015-0.003%) Eimeria bovis and Eimeria zuernii. For
slaughter) Monensin 5-30 g/ton* to provide improved feed efficiency and for reduction
and 50-360 mg/head/day in incidence of liver abscesses caused by
Tylosin 8-10 g/ton* to provide Fusobacterium necrophorum and
60-90 mg/head/day Arcanobacterium (Actinomyces) pyogenes
in growing-finishing cattle fed in
*90% dry-matter basis confinement for slaughter.
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Goats
9. FDA Status: No feed mill license required.
Regulation §558.195
WARNING STATEMENT REQUIRED: Do not feed to goats producing milk for human consumption.
CAUTION: Do not use Decoquinate in feeds containing bentonite.
LIMITATIONS FOR USE: Feed at least 28 days during periods of exposure to coccidiosis or when experience indicates
that it is likely to be a hazard. Type C feed may be prepared from dry or liquid Type B feed.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Young Goats Decoquinate 12.9-90.8 g/ton For the prevention of coccidiosis in
young goats caused by Eimeria
christenseni and Eimeria
ninakohlyakimovae.
LIMITATIONS FOR USE: Feed Type C feed or milk replacer at a rate to provide 22.7 mg per 100 lb.
(0.5 mg/kg) of bodyweight per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Decoquinate 90.9-535.7 g/ton For the prevention of coccidiosis in
young goats caused by Eimeria
christenseni and Eimeria
ninakohlyakimovae.
LIMITATIONS FOR USE: Feed Type C medicated feed supplements as a top dress or mix into the daily
ration to provide 22.7 mg/100 lb. (0.5 mg/kg) bodyweight per day.
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2021 Feed Additive Compendium | Additive Listings 185

Decoquinate (Continued)
Sheep
10. FDA Status: No feed mill license required.
Regulation §558.195
WARNING STATEMENT REQUIRED: Do not feed to sheep producing milk for human consumption.
CAUTION: Do not use Decoquinate in feeds containing bentonite.
LIMITATIONS FOR USE: Feed at least 28 days during periods of exposure to coccidiosis or when experience indicates
that it is likely to be a hazard. Type C feed may be prepared from dry or liquid Type B feed.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Young Sheep Decoquinate 12.9-90.8 g/ton For the prevention of coccidiosis in
young sheep caused by Eimeria
bakuensis, Eimeria crandallis,
Eimeria ovinoidalis and Eimeria parva.
LIMITATIONS FOR USE: Feed Type C medicated feed or milk replacer at a rate to provide 22.7 mg
per 100 lb. of bodyweight (0.5 mg/kg) per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Decoquinate 90.9-535.7 g/ton For the prevention of coccidiosis in
young sheep caused by Eimeria
bakuensis, Eimeria crandallis,
Eimeria ovinoidalis and Eimeria parva.
LIMITATIONS FOR USE: Feed Type C medicated feed supplements as a top dress or mix into the daily
ration to provide 22.7 mg per 100 lb. of bodyweight (0.5 mg/kg) per day.
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PRODUCT INFORMATION
Decoquinate
Trade Name: Deccox, Zoetis Inc., Kalamazoo, Mich. 49007; Package: 50-lb. bag; Concentration: 6% active ingredient; Carrier or
Diluent: Corn meal, soybean oil, lecithin and silicon dioxide; Expiration Date: 60 months; Manufacturing Suggestions: Decoquinate
should not be used in feeds containing bentonite.
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Denagard
(see Tiamulin)

Deracin
(see Chlortetracycline)

186 Additive Listings | 2021 Feed Additive Compendium