Drug Data Classification Mechanism of Indications Contraindications Adverse Nursing

action effects responsibilities

Generic Methyldopa is Methyldopa may Methyldopa is Contraindicated CNS: Before:
name: in a class of lower blood indicated for the with sedation,  Check
Methyldopa medication pressure by management of hypersensitivity to headache, doctor’s order
called stimulating central hypertension as methyldopa, active asthenia,  Assess
Patient’s hypertensives. inhibitory alpha- monotherapy or in hepatic disease weakness sensitivity to
dose: It works by adrenergic combination with previous methyldopa,
250mg TID relaxing the receptors, false hydrochlorothiazide. methyldopa CV: hepatic
blood vessels neurotransmissio Methyldopa therapy associated bradycardia, disease, renal
Route: Oral so that blood n and/or reduction injection is used to with liver disorder myocarditis failure,
can flow more of plasma renin manage dialysis
easily activity hypertensive crises Precaution: Dermatologic:  Assess
throughout the Use cautiously with rash seen as weight, skin
body previous liver eczema or color, lesions,
disease, renal lichenoid mucous
failure, dialysis, eruption, toxic membrane
bilateral epidermal color, lesions,
cerebrovascular necrolysis orientation,
disease; fever affect
pregnancy,  Educate
lactation Endocrine: client about
breast the drug, it’s
Interaction: enlargement, purpose and
Drug-drug: gynecomastia, importance
potentiation of the lactation
pressor effects of During:
sympathomimetic GI: nausea,  Check the
amines; increased vomiting, label twice
hypotension during distention,  Administer at
surgery with central constipation, the right dose
anesthetics hepatic and in the
necrosis right time
Drug-lab test:
 Do not crush
methyldopa may Hematologic:
nor chew
interfere with test Positive
tablets,
for urinary uric Coomb’s test, swallow
acid, serum hemolytic whole
creatine, AST, anemia, bone  Discontinue
urinary marrow drug if fever,
catecholamines depression abnormalities
in liver
Other: nasal function tests,
stuffiness, mild or jaundice
arthralgia, occurs
myalgia, septic  Discontinue
shock-like drug if
symptoms Coombs’-
positive
hemolytic
anemia
occurs

After:
 Monitor blood
counts
periodically to
detect
hemolytic
anemia
 Monitor
hepatic
function,
especially in
the first 6-8
weeks of
therapy or if
unexplained
fever appears
 Ensure that
methyldopa is
not reinstated
 in such
patients
 Report
unexplained,
prolonged
general
tiredness;
yellowing of
the skin or
eyes; fever;
bruising;
rash.
 Document
and record