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CFU Report - Cordlife (2017)
CFU Report - Cordlife (2017)
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INSIGHTȩ INTOȩ THEȩ FREQUENCIESȩ ANDȩ GROWTHȩ PROPERTIESȩ OFȩ HEMATOPOIETICȩ PROGENITORȩ CELLSȩ ATȩ VARIOUSȩ DEVELOPMENTALȩ
STAGESȩ !LTHOUGHȩ (3#Sȩ HAVEȩ THEȩ CAPACITYȩ TOȩ PROLIFERATEȩ ANDȩ DIFFERENTIATEȩ INȩ CULTUREȩ MOSTȩ CELLSȩ DETECTEDȩ INȩ
HEMATOPOIETICȩCULTUREȩASSAYȩCONSISTȩOFȩHEMATOPOIETICȩPROGENITORSȩWHICHȩHAVEȩLIMITEDȩSELF
RENEWALȩCAPACITYȩANDȩSHORTȩ
TERMȩ HEMATOPOIETICȩ POTENTIALȩ 0ROGENITORSȩ DETECTEDȩ INȩ CULTUREȩ ASSAYSȩ CANȩ EITHERȩ BEȩ MULTIPOTENTIALȩ CAPABLEȩ OFȩ
GENERATINGȩPROGENYȩOFȩMULTIPLEȩBLOODȩCELLȩTYPES ȩORȩRESTRICTEDȩTOȩONEȩORȩTWOȩLINEAGESȩERYTHROCYTESȩGRANULOCYTESȩ
MONOCYTESMACROPHAGESȩORȩPLATELETS
-ATUREȩ BLOODȩ CELLSȩ AREȩ SEENȩ TOȩ HAVEȩ LIMITEDȩ LIFEȩ SPANȩ ANDȩ AREȩ CONTINOUSLYȩ REPLACEDȩ BYȩ THEȩ PROLIFERATIONȩ ANDȩ DE
DIFFERENTIAIONȩȩOFȩAȩVERYȩSMALLȩPOPULATIONȩOFȩ@0LURIPOTENTȩ(3#Sȩ4HESEȩCELLSȩAREȩSEENȩPRIMARILYȩINȩTHEȩADULTȩBONEȩMARROWȩ
BUTȩ Aȩ VERYȩ PRIMITIVEȩ ANDȩ HIGHLYȩ PRODUCTIVEȩ FORMȩ OFȩ THESEȩ AREȩ FOUNDȩ INȩ THEȩ 5MBILICALȩ #ORDȩ "LOODȩ4HESEȩ CELLSȩ AREȩ
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