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Aripiprazole: Generic Name Brand Name Indications MOA
Aripiprazole: Generic Name Brand Name Indications MOA
receptors
Pimozide Orap indicated for the Pimozide selectively
suppression of motor inhibits type 2
and phonic tics in dopaminergic receptors in
patients with Tourette's the central nervous
Disorder who have failed system (CNS), thereby
to respond satisfactorily decreasing dopamine
to standard treatment. neurotransmission and
reducing the occurrence
of motor and vocal tics
and delusions of
parasitosis. In addition,
this agent antagonizes
alpha-adrenergic and 5-
HT2 receptors.
Porchloroperazine Compazine indicated in vertigo due prochlorperazine mainly
to Meniere's syndrome, blocks D2 dopamine
labyrinthitis and other receptors in the brain. It
causes, and for nausea can also block
and vomiting from any histaminergic, cholinergic,
cause including that and noradrenergic
associated with migraine. receptors.
It may also be used for
schizophrenia (especially
in the chronic stage),
acute mania and as an
adjunct to the short term
management of anxiety.
Quetiapine Seroquel For schizophrenia, acute The mechanism of action
manic episodes, and of SEROQUEL, as with
adjunctive treatment for other drugs having
major depressive efficacy in the treatment
disorder. of schizophrenia and
acute manic episodes
associated with bipolar
disorder, is unknown.
However, it has been
proposed that this drug=s
efficacy in schizophrenia is
mediated through a
combination of dopamine
type 2 (D2) and serotonin
type 2 (5HT2) antagonism.
Antagonism at receptors
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REFERENCES
https://www.rxlist.com/abilify-drug.htm#description
[Type here]
https://medlineplus.gov/druginfo/meds/a610015.html
https://go.drugbank.com/drugs/DB09128
https://www.webmd.com/drugs/2/drug-1444/chlorpromazine-oral/details#:~:text=This%20medication%20is%20used
%20to,take%20part%20in%20everyday%20life.
https://reference.medscape.com/drug/vraylar-cariprazine-999874
https://www.rxlist.com/prolixin-drug.htm
https://www.rxlist.com/clozaril-drug.htm#indications
https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018723s037lbl.pdf
https://www.rxlist.com/haldol-drug.htm#indications
https://www.medicines.org.uk/emc/product/968/smpc#gref
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159064/#:~:text=Adasuve%20is%20indicated%20for%20the,Mitigation
%20Strategy%20(REMS)%20program.
https://psychopharmacologyinstitute.com/publication/iloperidone-fanapt-indications-fda-approved-uses-2156#:~:text=FANAPT
%C2%AE%20tablets%20are%20indicated,of%20adult%20patients%20with%20schi
zophrenia.
https://psychopharmacologyinstitute.com/publication/lurasidone-indications-fda-approved-uses-2148
https://www.webmd.com/drugs/2/drug-7896/molindone-oral/details#:~:text=Molindone%20is%20used%20to%20treat,take
%20part%20in%20everyday%20life.
https://www.rxlist.com/invega-drug.htm
https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/089683s024lbl.pdf
https://www.webmd.com/drugs/2/drug-1644-9274/olanzapine-oral/olanzapine-oral/details
https://www.rxlist.com/orap-drug.htm
https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/207318lbl.pdf
https://www.medicines.org.uk/emc/product/4553/smpc#gref
https://www.ncbi.nlm.nih.gov/books/NBK459145/#:~:text=Indications-,Quetiapine%20is%20FDA%20approved%20for
%20schizophrenia%2C%20acute%20manic%20episodes%2C%20and,ages%2013%20to%2017%2C%20respectively
https://www.rxlist.com/risperdal-drug.htm#description
https://www.rxlist.com/thioridazine-drug.htm#indications
https://www.webmd.com/drugs/2/drug-11998/trifluoperazine-oral/details#:~:text=This%20medication%20is%20used
%20to,desire%20to%20hurt%20yourself%2Fother
https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018081s046_18082s031lbl.pdf
https://www.rxlist.com/geodon-drug.htm#indications
https://psychopharmacologyinstitute.com/publication/mechanism-of-action-of-aripiprazole-2119#:~:text=Aripiprazole%20is
%20a%20partial%20agonist,activity%20in%20the%20mesocortical%20pathway.
[Type here]
https://www.centerwatch.com/directories/1067-fda-approved-drugs/listing/4167-saphris-asenapine#:~:text=Weight
%20increased-,Mechanism%20of%20Action,D2%20and%205%2DHT2A%20receptors.
https://www.rexultihcp.com/mdd/clinical-pharmacology
https://www.ncbi.nlm.nih.gov/books/NBK553079/#:~:text=Go%20to%3A-,Mechanism%20of%20Action,receptors%20in%20the
%20mesolimbic%20pathway.
https://journals.sagepub.com/doi/full/10.1177/2045125320905752
https://www.physio-pedia.com/Clozapine_in_the_Treatment_of_Psychosis#:~:text=schizophrenic%2Fschizoaffective
%20patients.-,Mechanism%20of%20Action,the%20D4%20dopamine%20receptor.
https://pubchem.ncbi.nlm.nih.gov/compound/Fluphenazine#:~:text=Fluphenazine%20is%20a%20phenothiazine%20with,that
%20are%20associated%20with%20schizophrenia.
https://www.medicinenet.com/valproic_acid/article.htm#is_valproic_acid_available_as_a_generic_drug
https://www.ncbi.nlm.nih.gov/books/NBK560892/#:~:text=Go%20to%3A-,Mechanism%20of%20Action,drug%20achieves%20its
%20maximal%20effect.
https://go.drugbank.com/drugs/DB00502
https://go.drugbank.com/drugs/DB00408
https://www.medicinenet.com/lurasidone_hydrochloride_latuda/article.htm
https://go.drugbank.com/drugs/DB04946
https://go.drugbank.com/drugs/DB01618
https://pubchem.ncbi.nlm.nih.gov/compound/Perphenazine#:~:text=Perphenazine%20is%20a%20phenothiazine
%20derivative,of%20dopamine%20in%20the%20brain.
https://go.drugbank.com/drugs/DB00334
https://pubchem.ncbi.nlm.nih.gov/compound/Pimozide#:~:text=Pimozide%20selectively%20inhibits%20type%202,adrenergic
%20and%205%2DHT2%20receptors.
https://go.drugbank.com/drugs/DB05316
https:/www.ncbi.nlm.nih.gov/books/NBK537083/#:~:text=Go%20to%3A-,Mechanism%20of%20Action,%2C%20cholinergic%2C
%20and%20noradrenergic%20receptors.
https://psychopharmacologyinstitute.com/publication/mechanism-of-action-of-risperidone-2126#:~:text=Risperidone%20is
%20an%20SGA%20with,neurotransmission%20in%20the%20mesolimbic%20pathway.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/20639se1-017,016_seroquel_lbl.pdf
https://pubchem.ncbi.nlm.nih.gov/compound/Tiotixene#:~:text=Thiothixene%20blocks%20postsynaptic%20dopamine
%20receptors,such%20as%20hallucinations%20and%20delusions
https://pubchem.ncbi.nlm.nih.gov/compound/5566#:~:text=Trifluoperazine%20is%20a%20phenothiazine%20derivative,by
%20an%20excess%20of%20dopamine.
https://go.drugbank.com/drugs/DB00246
https://www.ncbi.nlm.nih.gov/books/NBK559112/#:~:text=Go%20to%3A-,Mechanism%20of%20Action,also%20by
%20inhibiting%20histone%20deacetylase .
[Type here]
https://www.sciencedirect.com/topics/neuroscience/5-ht-receptor
https://jamanetwork.com/journals/jamapsychiatry/article-abstract/492990
https://psychopharmacologyinstitute.com/publication/d2-receptors-psychopharmacology-2116
https://pubmed.ncbi.nlm.nih.gov/11392633/#:~:text=Muscarinic%20receptors%20have%20been
%20implicated,pre%2Dclinical%20and%20clinical%20studies&text=Behavioral%20studies%20suggest%20that
%20the,reflex%2C%20a%20measure%20of%20attention
https://www.sciencedirect.com/topics/neuroscience/histamine-receptor#:~:text=Introduction,histamine
%20receptors%20have%20been%20identified.
https://www.frontiersin.org/articles/10.3389/fphar.2019.00299/full
microgliahttps://www.everydayhealth.com/gaba/guide/#:~:text=Gamma%2Daminobutyric20acid%2C%20or
%20GABA,the%20neurons%20or%20nerve%20cells