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Maternal and Child Health Nursing, 8 Edition.: LESSON PREVIEW/REVIEW (5 Minutes)
Maternal and Child Health Nursing, 8 Edition.: LESSON PREVIEW/REVIEW (5 Minutes)
Maternal and Child Health Nursing, 8 Edition.: LESSON PREVIEW/REVIEW (5 Minutes)
LEUKEMIA (p.1512)
Leukemia is the distorted and uncontrolled proliferation of WBC’s and is the most frequently occurring type of cancer in
children
ACUTE LYMPHOCYTIC(LYMPHOBLASTIC) LEUKEMIA (ALL)
75% of leukemias THERAPEUTIC MANAGEMENT
involves lymphoblasts or immature WBC’s Up to 95% will have a first remission but if a child
With rapid proliferation of lymphoblasts, RBC and experiences a relapse, chances of long-term
platelet production fall and invasion of body survival are reduced to 70%
organs by the WBC’s begins Induction phase of chemotherapy- complete
highest incidence is between 2 to 6 years old remission or absence of leukemia cells
prognosis in those <1 is not as good as in those Sanctuary or consolidation phase- preventing
from 2-6 years old leukemia cells from invading or growing in the
more common in boys and in white children, CNS
children with Down’s syndrome or Fanconi 3rd, administering delayed intensive therapy
syndrome Maintenance phase-maintaining the original
remission
ASSESSMENT
1st symptoms: pallor, w-grade fever, lethargy CHEMOTHERAPY IN CHILDREN
(symptoms of anemia), petechiae and bleeding It involves administration via central venous
from oral mucous membranes and may bruise catheter or port to prevent irritation of vessel
easily because of low platelet count walls; also they can be clamped or trapped so the
As spleen and liver enlarge due to infiltration of child ca be ambulatory between treatments
abnormal cells, abdominal pain, vomiting and Drugs:
anorexia occur vincristine,
As abnormal lymphocytes invade the bone prednisone,
periosteum, bone and Joint point pain L-asparaginase,
COMPLICATIONS
Testicular Invasion- leukemic cells in the testes
will not be destroyed by chemotherapy therefore
irradiation is done leading to sterility
ACUTE MYELOID LEUKEMIA
MANAGEMENT
It involves the over proliferation of granulocytes Bone Marrow aspiration and Biopsy; cells are
neutrophils, basophils and eosinophils) typed to determine prognosis (M1 to M6)
Accounts for only 20% in childhood leukemias 1 to 2 months of Cytarabine and anthracycline
More frequent in late adolescence (daunorubicin) to achieve full remission
Granulocytes grow so rapidly they are often During maintenance phase, additional
forced out into the bloodstream while still in the chemotherapeutic agents like cyclophosphamide
blast stage. It results in limited production of RBC and 6-thioguanine are used usually for 6 to 9
and platelets months
Remission is difficult to achieve and is often brief
ASSESSMENT Bone Marrow transplantation is recommended
Same symptoms as ALL.
Susceptible to infection
WILM’S TUMOR/NEPHROBLASTOMA
Malignant cancer of the kidney; usually
unilateral; encapsulated at the time of STAGE DESCRIPTION
diagnosis I Tumor confined to 1 kidney and
completely removed surgically
INCIDENCE: most frequent abdominal tumor
II Tumor extending beyond the kidney but
and most common type of renal cancer; 1 :
completely removed surgically
200,000 to 250,000 children; peak – 3 yrs; III Regional spread of the disease beyond
increased incidence among siblings
SYMPTOMS
pain on urination,
frequency,
burning
hematuria, l
low-grade fever,
mild abdominal pain,
enuresis
**Urine for culture is obtained by a clean-catch technique
Multiple Choice
3. It occurs when children fail to respond to medications during an attack with an extreme emergency because a
child may die of heart failure due to a combination of exhaustion, atelectasis and acidosis from bronchial
plugging:
A. Status Asthmaticus
B. Urinary Tract Infection
C. Asthma
D. Acute Allergic Reaction
ANSWER: ________
RATIO:__________________________________________________________________________________________
_________________________________________________________________________________________________
______________________________________________________________
4. Malignant cancer of the kidney; usually unilateral; encapsulated at the time of diagnosis:
A. Acute Myeloid Leukemia
B. Nephroblastoma
C. Acute Lymphocytic Leukemia
D. Asthma
ANSWER: ________
RATIO:__________________________________________________________________________________________
_________________________________________________________________________________________________
______________________________________________________________
5. It involves lymphoblasts or immature WBC’s with rapid proliferation of lymphoblasts, RBC and platelet
production fall and invasion of body organs by the WBC’s begins:
A. Acute Myeloid Leukemia
B. Nephroblastoma
C. Acute Lymphocytic Leukemia
D. Asthma
ANSWER: ________
RATIO:__________________________________________________________________________________________
_________________________________________________________________________________________________
______________________________________________________________
7. A complication of Acute Lymphocytic Leukemia wherein the leukemic cells in the testes will not be destroyed
by chemotherapy therefore irradiation is done leading to sterility:
A. CNS involvement
B. Renal Involvement
C. Testicular Invasion
D. Wilm’s Tumor
ANSWER: ________
RATIO:__________________________________________________________________________________________
_________________________________________________________________________________________________
______________________________________________________________
8. A complication of Acute Lymphocytic Leukemia wherein blindness, hydrocephalus, recurrent seizures, nuchal
rigidity, headache, irritability:
A. CNS involvement
B. Renal Involvement
C. Testicular Invasion
D. Wilm’s Tumor
ANSWER: ________
RATIO:__________________________________________________________________________________________
_________________________________________________________________________________________________
______________________________________________________________
9. A complication of Acute Lymphocytic Leukemia wherein from invasion of leukemia cells the kidneys enlarge
and function impaired
A. CNS involvement
B. Renal Involvement
C. Testicular Invasion
D. Wilm’s Tumor
ANSWER: ________
RATIO:__________________________________________________________________________________________
_________________________________________________________________________________________________
______________________________________________________________
RATIONALIZATION ACTIVITY (THIS WILL BE DONE DURING THE FACE TO FACE INTERACTION)
The instructor will now rationalize the answers to the students. You can now ask questions and debate among yourselves.
Write the correct answer and correct/additional ratio in the space provided.
1. ANSWER: ________
You are done with the session! Let’s track your progress.
PERIOD 1
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
PERIOD 2
17 18 19 20 21 22 23 24 25 26 27 28 29 30 31
PERIOD 3
32 33 34 35 36 37 38 39 40 41 42 43 44 45 46
1. You will use index cards or half-sheets of paper to provide written feedback to the following questions:
a. What was the most useful or the most meaningful thing you have learned this session?
b. What question(s) do you have as we end this session?
2. Pass the responses to your instructor before you leave.
(For next session, review Common Health Problems in School Aged Children-Diabetes Mellitus p.1359,
Rheumatic Fever p. 1161, Juvenile Arthritis p. 1454, Common Parasitic Infection p.1225, Impetigo p.1216 .)