Batch : 2K19 (HMT.

IMP OF PHARMACOLOGY
From Last 6 Year Papers Of HNGU.
Based On ; K D Tripathi ( 8th Edi. ).
Here x* means ;Que is asked in supple. exam.
CHAPTER N0 PAGE QUE. YEAR

SECTION: 1 GENERAL PHARMACOLOGY.

1 10 Systemic route of drug administration (oral) 17*(15*)

1.
2 10-13 Routes of drug administration with Advantages 18
& Disadvantages of parenteral route

2. 1 22 Bioavailability & it's clinical importance 18*

1 33-4 Enzyme induction 16

2 34 Presystemic elimination (1stpass effect) 15*,19*

3.
3 38 Clearance 15

4 38 Explain 1st & 0 order of kinetics of elimination 19,21

5 39 Half life of drug 15,16*

1 54 G-protein coupled receptors 16*

4.
2 67-8 Receptor antagonism (drug antagonism) 16(18*,19)

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1 73 Enumerate factors modifying drug effects 18*

5. 2 80 Drug tolerance 17*,18

3 84 Clinical trial 17

6. 1 96 Super sensitivity 18

2 96 Idiosyncratic drug reaction 21

SECTION: 2 DRUGS ACTING ON A.N.S.

1 119-20 Neostigmine in myasthenia gravis 15

2 122 Atropine in organophosphate poisoning 15

7.
3 123 Treatment of organophosphate poisoning 16*,19*

4 123 Pharmacotherapy of organophosphate 17

poisoning

8. 1 129 Dicyclomine 15

9. 1 146,50 Dopamine in shock 15

2 150 Therapeutic uses of adrenaline 17*,18

1 153 Alpha blockers 16*

2 156 Pheochromocytoma 21

10 3 162 Atenolol 15

4 163 Clinical uses of beta adrenergic blocking drugs 19*

5 165 Labetalol 15*

6 166 Treatment of open angle glaucoma 16*,17,18*

7 169 Latanoprost in glaucoma 15*

8 169 Prostaglandins analogues used in glaucoma 16

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SECTION: 3 AUTACOIDS & RELATED DRUGS.

11. 1 182 Cetrizine 15

1 192 Therapeutic uses of migraine 17

12.
2 192 Pharmacotherapy of migraine 18,19,21

3 193 Treatment of severe migraine 16*

1 209 Mechanism of NSAIDS 17*

14.
2 211,221 COX-2 inhibtors (selective) 15*(18*)

3 223-4 Treatment of paracetamol poisoning 16

1 227 Pharmacotherapy of rheumatoid arthritis 21

2 228 Methotrexate in rheumatoid arthritis 15

15. 3 228-9 Immunomodulators acting via TNF-alpha in 19*

Rheumatoid arthritis

4 230 Pharmacotherapy of gout 18*

5 231 Pharmacological basis of uses of colchicine in 19*

acute gouty arthritis

6 232 Pharmacotherapy of chronic gout 16

7 233 Allopurinol 17

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SECTION:4 RESPIRATORY SYSTEM DRUGS.

1 237 Treatment of dry cough 17*

2 238 Mucolytics 21

3 241,50 Pharmacotherapy of asthma 15

4 241 Pharmacotherapy of chronic asthma 16*,17

16.
5 242-3 Beta-2 agonists as bronchodilators 17

6 250 Pharmacotherapy of COPD 18*

7 253 Pharmacotherapy of status asthmaticus 15*,18*,19,19*,21

8 Drug used in dry cough 15*

SECTION:5 HORMONES & RELATED DRUGS.

1 274 Pharmacotherapy of hyperthyroidism 17

2 275 Anti thyroid drugs 16

18. 3 277 Radioactive Iodine (I131) 18,21

4 278 Thyroid storm 19

5 Graves diseases 19*

1 284 Mechanism of action of insulin 18*

2 287 Insulin analogues 15*

19.
3 291 Tx / pharmacotherapy of diabetic ketoacidosis 15,17*,19

4 293 Oral hypoglycemic drugs 17

5 Pharmacotherapy of type 1 D.M. 16

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6 Pharmacotherapy of type 2 D.M. 16*,18

1 313 Synthetic corticosteroids 18*

2 314 Therapeutic uses of corticosteroids 19*

20. 3 317 Adverse effect of steroids 15*

4 317 Adverse effect & classification of corticosteroids 16*,17,19*,21

5 319 Indication & contraindication of corticosteroids 21

21. 1 325 Anabolic steroids 15*

1 345,48 Emergency contraception 16,18*

22.
2 346 Oral contraceptives : Mechanism of action & 19,21
therapeutic uses

3 350 Oral contraceptives : adverse effect 16*,17*,19,21

1 355&57 d/f b/w actions of oxytocin & ergometrine on 16*

23. uterus

2 358 Tocolytics 16,19

3 358 Beta 2 agonists as tocolytics 17*

1 362 Drugs used in tx. of osteoporosis 15

24.
2 366 Role of Vit D in Ca metabolism 17*

3 369 Biphosphates 19*

4 370 Osteoporosis 17

SECTION:6 DRUGS ACTING ON P.N.S.

25. 1 376 Compare : Succinylcholine v/s d-tubocurarine 19

2 382 Centrally acting m/s relaxants 16

1 392 Lidocaine as local anesthetic agent 15*

26.
2 392 Lignocaine / Lidocaine 16*

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SECTION:7 DRUGS ACTING ON C.N.S.

27. 1 408 I/V General Anesthetics 15*

28. 1 422 Tx Of Methanol Poisoning 16

29. 1 433 Zolpidem as short term hypnotic agent 15*

1 442 Carbamazepine 16*

30. Ethosumide in petit mal epilepsy (absence
2 443 15*
seizures)

3 450 Diazepam in Status Epilepticus 15

4 450 Pharmacotherapy of Status Epilepticus 18,18*,19,21

1 458 Seligiline (L-deprenyl) 15*

31.
2 459 COMT inhibitors 16

3 Pharmacotherapy of Parkinson's d/s 18

4 Combination of L-dopa & Carbidopa 19

1 470 Adverse effect of Antipsychotics 15,21

32.
2 474 Lithium Carbonate 15*

3 474 Lithium 19

4 478 Atypical Antipsychotics 16

1 482 Cheese reaction 17*,18

33.
2 487 Name of SSRI 21

34. 1 511 Pure Opioid Antagonists 19*

35. 1 517 Pharmacotherapy of Alzheimer's d/s 17*

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SECTION:8 DRUGS ACTING ON C.V.S.

1 530-5 ACE-IS 15
36.
2 531&33 ACE-IS : Uses & Adverse reaction 16*,18*,19

38. 1 561 Pharmacotherapy of Congestive cardiac failure 17,19*

1 584 Chronic stable Angina 19

2 585-90 Pharmacological basis of using organic nitrates 17*

in Angina Pectoris

40. 3 588 Organic Nitrates 15

4 591 Ca channel blocker 15*

5 598 K channel blocker 16

6 602 Tx of M.I. 18*,21

1 611 Central Sympatholytics 16

41.
2 617 Tx. of hypertension in pregnancy 19

SECTION:9 DRUGS ACTING ON KIDNEY.

1 626 Loop Acting Diuretics 15,19*

42. 2 634 K sparing diuretics 16*

3 Therapeutic uses of diuretics 17*,18

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SECTION:10 DRUGS AFFECTING BLOOD & IT' S FORMATION.

1 647-48 Oral iron preparations 15

2 651 Pharmacotherapy of Fe def. anemia 16,17*,18

3 652 Therapeutic uses of Vit B12 16*

44.
4 652 Vit B12 - role in erythropoiesis 17

5 655 Folic acid 19

6 656 Pharmacotherapy of Megaloblastic anemia 18*

7 656-7 Folinic acid rescue 19

1 663 Heparin 16

2 665 Low mol. weight heparin 15

3 665 Adverse effect of heparin 17

4 667 Oral anticoagulants 17

45.
5 667-8 Warfarin 15*

6 673 Fibrinolytic drugs 16*,21

7 676 Antiplatelet drugs 15

8 680 Role of antiplatelet drugs in coronary artery 19*

d/s

1 682 Hypolipidaemic drugs 17*

46.
2 683 HMG CoA reductase inhibitors 19*

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SECTION:11 G.I.T. DRUGS .

1 695 Pharmacotherapy of Peptic Ulcer 17,21

2 698 Famotidine in peptic ulcer 15*

47. 3 699 PPIS 16*,17,19*

4 703 Non systemic antacids 17*,18

5 705 Pharmacotherapy of H.pylori infection 18*

1 709 Classify drugs used in vomiting 19

2 710-15 Antiemetic drugs~classify 18

48.
3 710-15 Action,adverse effect & uses of Metodopramide 18

4 713 Prokinetic drugs 18*

49. 1 728-9 ORS 17,21

SECTION:12 ANTIMICROBIAL DRUGS .

1 744 Super Infection 17*

50. 2 747 Min. Inhibitory Contraceptive 17*

3 Rational antibiotic therapy 17

1 757 Cortimoxazole 17
51.
2 762 Tx. of Typhoid Fever 17,21

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1 768 Antibiotic resistance 15*,16

2 774 Beta lactamase inhibitors 21

52.
3 777 3rd generation cephalosporins 15*,19*

4 779-81 Noscomial infection(hospital acquired infection) 18

53. 1 815 Pharmacotherapy of tuberculosis 15*

1 794 Enumerate adverse effects of aminoglycosides 18,19

54.
2 794 Shared toxicities of aminoglycosides 21

55. 1 809-12 Drugs used in UTI (urinary tract infection) 15

1 815 Pharmacotherapy of category 1 tuberculosis 16*,17

56. 2 816 Isoniazid 19

3 825 MDR Tuberculosis (multi drug resistant) 19*

57. 1 834-5 Pharmacotherapy of leprosy 15

1 841 Tx. of candidiasis 18

58. 2 847 Topical antifungal drugs 16,19*

3 Therapeutic uses of antifungal drugs 18

1 861-7 Drugs used in HIV infection 15*

60. 2 868 HAART 16,17*

3 Pharmacotherapy of HIV AIDS 19*

1 873 Pharmacotherapy of P.Falciparum malaria 18

2 875 Suppresive prophylaxis of malaria 21

61. 3 877 Chloroquine resistance 16

4 878 Complicated P.Falciparum malaria 19

5 887 Artesunate 16*

6 Chemoprophylaxis of malaria 15*

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1 894 Metronidazole 15,19

2 894 Luminal amoebicides 16*

62. 3 895 Therapeutic uses of metronidazole 17*

4 899 Pharmacotherapy of acute amoebic dysentery 17*,18

5 899 Tx. of amoebiasis 21

6 900 Tx. of hepatic amoebiasis 18*

63. 1 908 Albendazole 15

SECTION:13 CHEMOTHERAPY OF NIOPLASTIC DISEASES .

1 914 Principles Of Cancer Chemotherapy & selection 18

of drug
64.
2 916 Classification & adverse effect of Anticancer 16*
drugs

SECTION:14 MISCELLANEOUS DRUGS .

66. 1 952 Acne Vulgaris 18

67. 1 961 Pharmacotherapy of scabies 18*

69. 1 968 Vit -A 16

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EXTRA QUE .

1 General principle in prescribing drugs in patients with renal failure. 18

2 Role of enz. in therapeutics of d/s. 18*

3 Plasma expanders. 18*

4 Recombinat DNA technology. 18*

5 Generalized tonic clonic seizures. 19*

6 Postcoital pill. 19*

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