5/8/2019

Microbotox
Yasmina Ahmed El Attar
Lecturer
Dermatology & venereology department
Faculty of medicine
Tanta university

Mesobotox verus Microbotox

The Same

• Mesobotox: this term was neither sufficiently scientific nor did it

convey the extent or depth of the injections over the target areas

• Microbotox reflects the small doses of toxin delivered in each

microdroplet.

1
 5/8/2019

Microbotox
Microbotox is the injection of multiple microdroplets of diluted
onabotulinumtoxinA into the dermis
or the interface between the dermis and the superficial layer of facial
muscles.

Botox
It was recommended in botox :
• to use a dilution of 2.0–2.5 mL of saline for every 100 units of Botox.
Injections of 2–4 Botox units (0.05– 0.1 mL) were delivered to target
muscles

• Complete muscle paralysis in addition,

the smooth lustrous appearance of the forehead

skin due to decreased sweat and sebaceous gland
activity was an aesthetic bonus.

2
 5/8/2019

Microbotox
• Small injection volumes would prevent unwanted diffusion of the
solution into deeper muscles,
• thus retaining more muscle function to give a natural appearance.

• Superficial muscle weakening

Microbotox

• The duration of improvement after a session of Microbotox typically

lasts for 3–4 months and some cases up to 6 months.

3
 5/8/2019

BOTOX

4
 5/8/2019

Microbotox

• The intention is to decrease sweat and sebaceous gland activity to

improve skin texture and sheen
• and to target the superficial layer of muscles (that find attachment to the
undersurface of the dermis) causing visible rhytides.

Microbotox

• Attenuation of disturbing lines • Smoothen horizontal creases,

and wrinkles yet to retain a • Improving contouring of the
cervicomental angle.
natural animated appearance:
• Decrease vertical banding of the neck, as
well as to achieve better apposition of the
platysma to the jawline and neck,
➢Brow and forehead
➢The under-eye lines, • Improve skin texture,
➢Lower face • Decrease oiliness of the central
T zone of the face and cheeks

5
 5/8/2019

Microbotox

• The Microbotox solution is mixed in the syringe by adding a small volume of lidocaine to the
calculated dose of onabotulinumtoxin A drawn from a standard bottle of Botox prepared with
2.5 mL saline.
• Each 1mL syringe of Microbotox solution contains 20–28 units of onabotulinumtoxinA per mL
of solution
• and is used to deliver 100–120 injections.

Microbotox

• 20 units in 1 mL of solution.
• multiple tiny blebs of diluted Botox at 0.8- to 1.0- cm

• This is equivalent to reconstituting

• a bottle of Botox with 5.0 mL saline and then directly drawing out 1
mL of the solution into the syringe.

• However, it is more convenient to use Botox from a bottle of 100

units that has been reconstituted with 2.5 mL of saline

6
 5/8/2019

Microbotox

COMPLICATIONS
• Most complications have arisen from mistakes with droplet size and
depth of injection.
• The Microbotox will diffuse into the thickness of the underlying muscle
creating total paralysis rather than mere superficial muscle weakening.

Microbotox

• 0.05-mL droplet can further be divided into 20–30 smaller Microbotox droplets
• 100 and 120 injections with each 1 mL

7
 5/8/2019

Microbotox

3 fingerbreadths
above the mandibular border,

one fingerbreadth
posterior to the depressor anguli oris

Before After

8
 5/8/2019

Microbotox

Before After

9
5/8/2019

10
5/8/2019

11
5/8/2019

12
 5/8/2019

• The dermis can be treated with microdroplets (0.001 cc) solution

at a thousand of injection sites using an injector.
• The author invented a unique injection solution in which S-HA is
mixed botulinum toxin A.

13
 5/8/2019

• With a 1-mm depth setting on the automatic injector, the actual

injection depth on the face was approximately 0.5–0.9 mm because
of the bevel of the needle tip.

The hydrotoxin method in a 61-year-old woman. A, C, Before. B, D, 4 weeks after fine wrinkles in
the crow’s feet area and anterior malar area improved and became shiny.

14
5/8/2019

15
 5/8/2019

Triple therapy in keloids and scars

(IPL+ IL Microbotox + IL Triamcinolone )

IPL : 640 nm crystal filter

28 units in 1 mL of microbotox solution.

0.2 ml of IL triamcinolone

Microbotox

• Attenuation of disturbing lines • Smoothen horizontal creases,

and wrinkles yet to retain a
• Improving contouring of the
natural animated appearance:
cervicomental angle.
➢Brow and forehead
➢The under-eye lines, • Improve skin texture,
• Wide pores treatment
➢Lower face
• Decrease oiliness of the central
T zone of the face and cheeks

16
 5/8/2019

Thank you for your kind attention

17