Benefit Drug List

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Page 1 of 65

BC Cancer Benefit Drug List


April 2022

DEFINITIONS
Class I Reimbursed for active cancer or approved treatment or approved indication only.
Reimbursed for approved indications only. Completion of the BC Cancer Compassionate Access Program Application (formerly Undesignated Indication Form) is necessary to provide
Restricted Funding (R)
the appropriate clinical information for each patient.
NOTES
1. BC Cancer will reimburse, to the Communities Oncology Network hospital pharmacy, the actual acquisition cost of a Benefit Drug, up to the maximum price as determined by BC Cancer, based on the current brand
and contract price.  Please contact the OSCAR Hotline at 1-888-355-0355 if more information is required.
2. Not Otherwise Specified (NOS) code only applicable to Class I drugs where indicated.
3. Intrahepatic use of chemotherapy drugs is not reimbursable unless specified.
4. For queries regarding other indications not specified, please contact the BC Cancer Compassionate Access Program Office at 604.877.6000 x 6277 or cap_bcca@bccancer.bc.ca

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
Therapy for Metastatic Castration-Sensitive Prostate Cancer using
abiraterone tablet Genitourinary UGUMCSPABI R
Abiraterone and Prednisone
Palliative Therapy for Metastatic Castration Resistant Prostate Cancer
abiraterone tablet Genitourinary UGUPABI R
Using Abiraterone and prednisone
Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia or
acalabrutinib capsule Lymphoma LYACAL I
Small Lymphocytic Lymphoma using Acalabrutinib
Treatment of Previously Untreated Chronic Lymphocytic Leukemia or
acalabrutinib capsule Lymphoma ULYFACAL R
Small Lymphocytic Lymphoma using Acalabrutinib
acitretin capsule Lymphoma reversal of early dysplastic and neoplastic stem changes LYNOS I
first-line treatment of epidermal growth factor receptor mutation-positive
afatinib tablet Lung LUAVAFAT I
advanced non-small cell lung cancer with afatinib
aldesleukin injectable Skin & Melanoma Treatment of In-Transit Melanoma with Intralesional Aldesleukin IL-2 SMILALD I
pediatric patients with high risk neuroblastoma treated on the ANBL0032
aldesleukin injectable Pediatric I
study

treatment of pediatric patients with high-risk neuroblastoma who achieve a


aldesleukin injectable Pediatric response to prior first-line multi-agent, multimodal therapy using R
dinutuximab in combination with sargramostim, aldesleukin and tretinoin

treatment of ALK-positive advanced non-small cell lung cancer with


alectinib capsule Lung LUAVALE I
alectinib
treatment of fludarabine-refractory B-chronic lymphocytic leukemia and T-
alemtuzumab injectable Lymphoma LYALEM I
prolymphocytic leukemia
Treatment of Cutaneous T-Cell Lymphoma (Mycosis Fungoides/ Sézary
alitretinoin tablet Lymphoma LYALIT I
Syndrome)

Only reimbursable when


aminolevulinic acid prescribed by physicians in the
topical solution Skin & Melanoma topical therapy for skin cancer with PDT (Photodynamic Therapy) SMPDT I
(LEVULAN® KERASTICK®) Skin Tumour Group within the BC
Cancer Skin PDT Program

amsacrine injectable Leukemia & BMT LKNOS I


patients with thrombocytosis related to a myeloproliferative disorder who
anagrelide capsule Leukemia & BMT have had an inadequate response to or are intolerant of hydroxyurea LKANAG I
and/or interferon

* denotes change
Page 2 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
neoadjuvant or adjuvant therapy for breast cancer using anastrozole in
anastrozole tablet Breast BRAJANAS I
postmenopausal women

neoadjuvant or adjuvant ovarian suppression and aromatase inhibitor in


anastrozole tablet Breast BRAJLHRHAI I
premenopausal women with high-risk early stage breast cancer

first or second line hormonal treatment for advanced breast cancer in


anastrozole tablet Breast BRAVANAS I
postmenopausal women
therapy for advanced breast cancer using a LHRH agonist and an
anastrozole tablet Breast BRAVLHRHA I
aromatase inhibitor
therapy of advanced breast cancer using palbociclib and aromatase
anastrozole (cont'd) tablet Breast BRAVPALAI I
inhibitor with or without LHRH agonist
therapy of advanced breast cancer using ribociclib and aromatase
anastrozole (cont'd) tablet Breast BRAVRIBAI I
inhibitor with or without LHRH agonist

hormonal treatment for advanced endometrial cancer in postmenopausal


anastrozole (cont'd) tablet Gynecology GOENDAI I
women with contraindications to tamoxifen or intolerant of tamoxifen

anastrozole (cont'd) tablet Gynecology therapy for advanced ovarian cancer using an aromatase inhibitor GOOVAI I
Treatment of Metastatic Castration Sensitive Prostate Cancer using
apalutamide tablet Genitourinary UGUMCSPAPA R
Apalutamide
Treatment of Non- Metastatic Castration Resistant Prostate Cancer Using
apalutamide tablet Genitourinary UGUPAPA R
Apalutamide
first-line induction and consolidation therapy of acute promyelocytic
arsenic trioxide injectable Leukemia & BMT LKATOATRA I
leukemia using arsenic trioxide and tretinoin
first-line induction and consolidation therapy of acute promyelocytic
arsenic trioxide injectable Leukemia & BMT LKATOP I
leukemia using arsenic trioxide, tretinoin and daunorubicin

induction and consolidation therapy of relapsed acute promyelocytic


arsenic trioxide injectable Leukemia & BMT LKATOR I
leukemia using arsenic trioxide and tretinoin (All-Trans Retinoic Acid)

asparaginase
injectable Leukemia & BMT LKNOS, LYNOS I
(KIDROLASE®)

treatment of acute lymphoblastic leukemia and lymphoblastic lymphoma


asparaginase-erwinia
injectable Leukemia & BMT using asparaginase-Erwinia (Erwinase®) in patients allergic to LKNOS, LYNOS I
(ERWINASE®)
asparaginase (Kidrolase®) or pegaspargase (Oncaspar®)

First-Line Treatment of Advanced Hepatocellular Carcinoma using


atezolizumab injectable Gastrointestinal GIATZB* I
Atezolizumab and Bevacizumab
atezolizumab injectable Lung treatment of advanced non-small cell lung cancer LUAVATZ I
treatment of advanced non-small cell lung cancer using 4-weekly
atezolizumab injectable Lung LUAVATZ4 I
atezolizumab
second-line treatment of recurrent or metastatic merkel cell carcinoma
avelumab injectable Skin & Melanoma SMMCCAVE I
using avelumab
axitinib tablet Genitourinary therapy for metastatic renal cell carcinoma using axitinib GUAXIT I
Treatment of Metastatic Renal Cell Carcinoma Using Pembrolizumab and
axitinib tablet Genitourinary GUAVPEMAX I
Axitinib
azacitidine injectable Leukemia & BMT therapy of acute myeloid leukemia using azacitidine and sorafenib LKAMLAS I
azacitidine (cont'd) injectable Leukemia & BMT therapy of myelodysplastic syndrome ULKMDSA R
bacillus calmette guerin Therapy for High- or Intermediate-Risk Non-Muscle Invasive Bladder
injectable Genitourinary GUBCG I
(BCG) Cancer using BCG

* denotes change
Page 3 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
bendamustine injectable Lymphoma treatment of Non-Hodgkin Lymphoma with bendamustine LYBEND I

bendamustine (cont'd) injectable Lymphoma treatment of Non-Hodgkin Lymphoma with bendamustine and rituximab LYBENDR I

bendamustine injectable Lymphoma treatment of relapsed chronic lymphocytic leukemia with bendamustine LYCLLBEND I

treatment of relapsed/refractory chronic lymphocytic leukemia or small


bendamustine injectable Lymphoma LYCLLBENDR I
lymphocytic lymphoma with bendamustine and rituximab
treatment of previously untreated chronic lymphocytic leukemia (CLL) with
bendamustine (cont'd) injectable Lymphoma LYCLLFBR I
bendamustine and rituximab
treatment of rituximab-refractory follicular lymphoma with obinutuzumab in
bendamustine (cont'd) injectable Lymphoma LYOBBEND I
combination with bendamustine
Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma and
bendamustine injectable Lymphoma Not Eligible for Transplant using Polatuzumab Vedotin, Bendamustine and LYPOLABR* I
Rituximab
First-Line Treatment of Advanced Hepatocellular Carcinoma using
bevacizumab injectable Gastrointestinal GIATZB* I
Atezolizumab and Bevacizumab
palliative therapy of metastatic colorectal cancer using capecitabine and
bevacizumab injectable Gastrointestinal GIAVCAPB I
bevacizumab
palliative combination chemotherapy for metastatic colorectal cancer using
bevacizumab injectable Gastrointestinal GICIRB I
irinotecan, bevacizumab and capecitabine
palliative combination chemotherapy for metastatic colorectal cancer using
bevacizumab injectable Gastrointestinal GICOXB I
oxaliplatin, bevacizumab and capecitabine

palliative combination chemotherapy for metastatic colorectal cancer using


bevacizumab (cont'd) injectable Gastrointestinal GIFFIRB I
irinotecan, fluorouracil, folinic acid (leucovorin) and bevacizumab

palliative combination chemotherapy for metastatic colorectal cancer using


bevacizumab (cont'd) injectable Gastrointestinal GIFFOXB I
oxaliplatin, fluorouracil, leucovorin, and bevacizumab
bevacizumab (cont'd) injectable Neuro-Oncology patients with relapsed malignant gliomas CNBEV I
alternative treatment of gynecological malignancies using bevacizumab,
bevacizumab (cont'd) injectable Gynecology GOCABRBEV I
carboplatin and paclitaxel NAB (ABRAXANE) Note: Biosimilar bevacizumab
Alternative Treatment of Gynecological Malignancies using Bevacizumab, (ZIRABEV®, MVASI®) is funded
bevacizumab (cont'd) injectable Gynecology GOCISPBEV I
Cisplatin and Paclitaxel for treatment started on or after
primary treatment of metastatic/recurrent cancer of the cervix with November 1st, 2019. AVASTIN®
bevacizumab (cont'd) injectable Gynecology GOCXCATB I
bevacizumab, carboplatin and paclitaxel is funded for treatment started
treatment of platinum resistant epithelial ovarian cancer with bevacizumab prior to November 1st, 2019.
bevacizumab (cont'd) injectable Gynecology GOOVBEVG I
and gemcitabine
treatment of platinum resistant epithelial ovarian cancer with bevacizumab
bevacizumab injectable Gynecology GOOVBEVLD I
and pegylated liposomal doxorubicin
treatment of platinum resistant epithelial ovarian cancer with bevacizumab
bevacizumab (cont'd) injectable Gynecology GOOVBEVP I
and paclitaxel
treatment of platinum resistant epithelial ovarian cancer with bevacizumab
bevacizumab injectable Gynecology GOOVBEVV I
and vinorelbine
primary treatment of invasive epithelial ovarian, fallopian tube and primary
bevacizumab (cont'd) injectable Gynecology peritoneal cancer with high risk of relapse using bevacizumab, carboplatin GOOVCATB I
and paclitaxel
treatment with bevacizumab as a single agent or in combination with
bevacizumab (cont'd) Pediatric chemotherapy for pediatric patients with low-grade gliom progressing after I
first-line chemotherapy
therapy for advanced solitary fibrous tumours and hemangiopericytoma
bevacizumab (cont'd) Sarcoma SATEMBEV I
using temozolomide and bevacizumab
Approval from Health Canada
bexarotene (SAP) capsule Lymphoma patients with refractory cutaneous T-cell lymphoma LYMFBEX I Special Access Programme is
required for each patient.
bicalutamide tablet Genitourinary Treatment of Prostate Cancer with High-Dose Bicalutamide GUPHDBIC I Not reimbursed for vasomotor
bicalutamide tablet Genitourinary Non-Steroidal Treatment of Prostate Cancer, at 50 mg po daily GUPNSAA I symptoms (hot flashes)

* denotes change
Page 4 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
therapy of non-dysgerminomatous ovarian germ cell cancer using
bleomycin injectable Gynecology GOBEP I
bleomycin, etoposide, and cisplatin
curative therapy for germ cell cancer using with bleomycin, etoposide,
bleomycin injectable Genitourinary GUBEP I Not reimbursed for pleurodesis
cisplatin for germ cell cancers
palliative therapy for kaposi’s sarcoma using vinblastine alternating with
bleomycin injectable Kaposi's Sarcoma KSVB I
vincristine
treatment of Hodgkin lymphoma with doxorubicin, bleomycin, vinblastine,
bleomycin (cont'd) injectable Lymphoma LYABVD I
and dacarbazine
treatment of Hodgkin's Disease with cyclophosphamide, vinblastine,
bleomycin injectable Lymphoma LYCVPPABO I Not reimbursed for pleurodesis
procarbazine and prednisone
Other tumour site code
Not Otherwise
bleomycin injectable followed by ‘NOS’ (e.g. I
Specified LYNOS)
treatment of Philadelphia chromosome (Ph)-positive or Ph-negative
blinatumomab injectable Leukemia & BMT refractory or relapsed pre-B-cell acute lymphoblastic leukemia with ULKBLIN R
blinatumomab
treatment of pediatric patients with Philadelphia chromosome-negative (Ph-
blinatumomab injectable Leukemia & BMT ) relapsed or refractory pre-B-cell acute lymphoblastic leukemia using R
blinatumomab
Bortezomib, Lenalidomide and Dexamethasone for Previously Untreated
bortezomib injectable Myeloma UMYBLDF R
Multiple Myeloma
maintenance therapy for multiple myeloma using bortezomib for patients
bortezomib injectable Myeloma MYBORMTN I
with the high-risk chromosome abnormality

treatment of multiple myeloma using bortezomib, dexamethasone with or


injectable Myeloma MYBORPRE I
without cyclophosphamide as induction pre-stem cell transplant

treatment of relapsed multiple myeloma using bortezomib,


bortezomib injectable Myeloma MYBORREL I
dexamethasone with or without cyclophosphamide
treatment of relapsed and refractory multiple myeloma with daratumumab
bortezomib (cont'd) injectable Myeloma in combination with bortezomib and dexamethasone with or without UMYDARBD R
cyclophosphamide
treatment of multiple myeloma using melphalan, prednisone and weekly
bortezomib (cont'd) injectable Myeloma bortezomib with the option of substituting cyclophosphamide for MYMPBOR I
melphalan
bosutinib tablet Leukemia & BMT treatment of chronic myeloid leukemia using bosutinib LKCMLB I

Treatment of Previously Untreated, Stage IV Hodgkin Lymphoma with


brentuximab vedotin injectable Lymphoma LYAVDBV I
Doxorubicin, Vinblastine, Dacarbazine and Brentuximab Vedotin

treatment of Hodgkin lymphoma and anaplastic large cell lymphoma with


brentuximab vedotin injectable Lymphoma LYBRENTUX I
brentuximab vedotin

treatment for consolidation therapy post-autologous stem cell transplant


brentuximab vedotin injectable Lymphoma LYBV I
(ASCT) for Hodgkin lymphoma using brentuximab vedotin

treatment of CD30-positive peripheral T-Cell Lymphoma (PTCL) with


brentuximab vedotin
injectable Lymphoma doxorubicin, cyclophosphamide, prednisone (CHP) and brentuximab LYCHPBV I
(cont'd)
vedotin
Treatment of Cutaneous T-Cell Lymphoma (CTCL) with Brentuximab
brentuximab vedotin injectable Lymphoma LYCTCLBV I
Vedotin
bromocriptine tablet, capsule Neuro-Oncology therapy for pituitary adenomas using bromocriptine CNB I

* denotes change
Page 5 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES

long-acting neoadjuvant or adjuvant ovarian suppression and aromatase inhibitor in


buserelin Breast BRAJLHRHAI I
injectable premenopausal women with high-risk early stage breast cancer

neoadjuvant or adjuvant therapy for breast cancer using a LHRH agonist


buserelin (cont'd) injectable Breast BRAJLHRHT I
and tamoxifen
therapy for advanced breast cancer using a LHRH agonist and an
buserelin injectable Breast BRAVLHRHA I
aromatase inhibitor
combination therapy with tamoxifen as palliative therapy for metastatic
buserelin injectable Breast BRAVLHRHT I
breast cancer
Not reimbursed for endometriosis
therapy of advanced breast cancer using palbociclib and aromatase
buserelin injectable Breast BRAVPALAI I
inhibitor with or without LHRH agonist
Therapy of Advanced Breast Cancer using Palbociclib and Fulvestrant
buserelin injectable Breast BRAVPBFLV I
with or without LHRH Agonist
Therapy of Advanced Breast Cancer using Ribociclib and Fulvestrant with
buserelin injectable Breast BRAVRBFLV I
or without LHRH Agonist
therapy of advanced breast cancer using ribociclib and aromatase
buserelin injectable Breast BRAVRIBAI I
inhibitor with or without LHRH agonist
buserelin (cont'd) injectable Genitourinary therapy for prostate cancer using LHRH agonist GUPLHRH I
Tumour site code
Not Otherwise
busulfan tablet followed by ‘NOS’ I
Specified
(e.g. LKNOS)
myeloablative conditioning therapy prior to hematopoietic stem cell
busulfan injectable Leukemia & BMT BMTIVBUCY I
transplantation for myeloid malignancies
busulfan injectable Pediatric pediatric patients who cannot swallow oral busulfan I
palliative therapy for metastatic castration resistant prostate cancer using
cabazitaxel injectable Genitourinary GUPCABA I
cabazitaxel and prednisone
cabergoline tablet Neuro-Oncology therapy for pituitary adenomas using cabergoline CNCAB I

cabozantinib tablet Gastrointestinal Treatment of Advanced Hepatocellular Carcinoma using Cabozantinib UGICABO R

cabozantinib tablet Genitourinary therapy for metastatic renal cell carcinoma using cabozantinib GUCABO I

* denotes change
Page 6 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
capecitabine tablet Breast therapy of adjuvant breast cancer using capecitabine BRAJCAP I
metastatic breast cancer as first line treatment if anthracyclines and
taxanes contraindicated, or where sidfect profile and/or treatment delivery
capecitabine (cont'd) tablet Breast concerns favour initial use of BRAVCAP; second or third line treatment of BRAVCAP I
metastatic breast cancer that has previously responded to an
anthracycline and taxane

capecitabine tablet Breast therapy for metastatic breast cancer using capecitabine and lapatinib BRAVLCAP I

palliative therapy for metastatic breast cancer using trastuzumab and


capecitabine tablet Breast BRAVTCAP I
capecitabine
capecitabine tablet Gastrointestinal adjuvant therapy of colon cancer using capecitabine GIAJCAP I
adjuvant combination chemotherapy for stage III and IIB colon cancer with
capecitabine tablet Gastrointestinal GIAJCAPOX I
oxaliplatin
first line palliative therapy of metastatic or unresectable colorectal
capecitabine (cont'd) tablet Gastrointestinal GIAVCAP I
adenocarcinoma in a patient either not suitable for or refusing GIIRFUFA
palliative therapy of metastatic colorectal cancer using capecitabine and
capecitabine (cont'd) tablet Gastrointestinal GIAVCAPB I
bevacizumab
combined modality therapy for metastatic rectal carcinoma using
capecitabine tablet Gastrointestinal GIAVCRT I
capecitabine and radiation therapy
palliative therapy of metastatic neuroendocrine cancer using
capecitabine tablet Gastrointestinal GIAVTZCAP I
temozolomide and capecitabine
capecitabine (cont'd) tablet Gastrointestinal Adjuvant Therapy of Biliary Cancer using Capecitabine GIBAJCAP I

palliative combination chemotherapy for metastatic colorectal cancer using


capecitabine (cont'd) tablet Gastrointestinal GICAPIRI I
irinotecan and capecitabine in patients unsuitable for GIFOLFIRI

palliative combination chemotherapy for metastatic colorectal cancer using


capecitabine (cont'd) tablet Gastrointestinal GICAPOX I
oxaliplatin and capecitabine
combination with mitomycin and radiation therapy as curative combined
capecitabine (cont'd) tablet Gastrointestinal GICART I
modality therapy for carcinoma of the anal canal
palliative combination chemotherapy for metastatic colorectal cancer using
capecitabine (cont'd) tablet Gastrointestinal GICIRB I
irinotecan, bevacizumab and capecitabine
palliative combination chemotherapy for metastatic colorectal cancer using
capecitabine (cont'd) tablet Gastrointestinal GICOXB I
oxaliplatin, bevacizumab and capecitabine
curative-intent combined modality therapy for cancer of the anal canal,
capecitabine (cont'd) tablet Gastrointestinal GICPART I
using cisplatin, capecitabine and radiation therapy
adjuvant chemotherapy in gastric cancer patients with D2 resection (node
capecitabine (cont'd) tablet Gastrointestinal negative) or ineligible for adjuvant chemoradiation using oxaliplatin and GIGAJCOX I
capecitabine
adjuvant chemotherapy in gastric cancer patients with completely
capecitabine (cont'd) tablet Gastrointestinal resected gastric cancer using cisplatin and capecitabine and radiation GIGAJCPRT I
therapy
palliative therapy of metastatic or locally advanced anal squamous cell
capecitabine (cont'd) tablet Gastrointestinal GIGAVCC I
carcinoma using cisplatin and capecitabine
Palliative Treatment of Metastatic or Locally Advanced Gastric,
capecitabine (cont'd) tablet Gastrointestinal Gastroesophageal Junction or Esophageal Adenocarcinoma using GIGAVCCT I
Cisplatin, Capecitabine and Trastuzumab

* denotes change
Page 7 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
Palliative Treatment of Metastatic or Locally Advanced Gastric,
capecitabine (cont'd) tablet Gastrointestinal Gastroesophageal Junction or Esophageal Carcinoma using Capecitabine GIGAVCOX I
and Oxaliplatin
palliative treatment of metastatic or locally advanced gastric,
capecitabine (cont'd) tablet Gastrointestinal gastroesophageal junction, or esophageal adenocarcinoma using GIGAVCOXT I
capecitabine, oxaliplatin and trastuzumab
treatment of operable cancer of the stomach, stomach-esophagus
capecitabine (cont'd) tablet Gastrointestinal junction or lower 1/3 esophagus, given before and after surgery, using GIGECC I
epirubicin, cisplatin and capecitabine
adjuvant chemotherapy for resected pancreatic adenocarcinoma using
capecitabine (cont'd) tablet Gastrointestinal GIPAJGCAP I
capecitabine and gemcitabine
second line treatment of metastatic or unresectable pancreatic
capecitabine (cont'd) tablet Gastrointestinal GIPAVCAP I
adenocarcinoma using capecitabine
Adjuvant or Neoadjuvant Combination Chemotherapy for Stage III Rectal
capecitabine (cont'd) tablet Gastrointestinal GIRAJCOX I
Cancer using Oxaliplatin and Capecitabine
adjuvant capecitabine therapy for stage II and III rectal cancer previously
capecitabine (cont'd) tablet Gastrointestinal GIRCAP I
treated with preoperative radiotherapy
combined modality adjuvant therapy for high risk rectal carcinoma using
capecitabine (cont'd) tablet Gastrointestinal GIRCRT I
capecitabine and radiation therapy
combined modality adjuvant therapy for high risk rectal carcinoma using
capecitabine (cont'd) tablet Gastrointestinal GIRINFRT I
capecitabine, infusional fluorouracil and radiation therapy
treatment of recurrent or metastatic squamous cell cancer of the head and
capecitabine (cont'd) tablet Head and Neck HNAVCAP I
neck with capecitabine
treatment of recurrent or metastatic nasopharyngeal cancer with
capecitabine (cont'd) tablet Head and Neck HNNAVCAP I
capecitabine
neoadjuvant or adjuvant therapy for breast cancer using carboplatin,
carboplatin injectable Breast BRAJDCARBT I
docetaxel and trastuzumab
palliative therapy for metastatic breast cancer using cisplatin and
carboplatin (cont'd) injectable Breast BRAVGEMP I
gemcitabine

neoadjuvant therapy for triple-negative breast cancer using carboplatin


carboplatin (cont'd) injectable Breast BRLACTWAC I
and weekly paclitaxel followed by doxorubicin and cyclophosphamide

Neoadjuvant Therapy for Triple-Negative Breast Cancer using Dose-


carboplatin (cont'd) injectable Breast Dense Therapy: Carboplatin and Weekly Paclitaxel Followed by BRLACTWACG I
Doxorubicin and Cyclophosphamide

carboplatin injectable Neuro-Oncology carboplatin and etoposide in the treatment of recurrent ependymoma CNCARV I

First-Line Palliative Treatment of Metastatic Anal Squamous Cell


carboplatin (cont'd) injectable Gastrointestinal GIAAVCT I
Carcinoma using Carboplatin and Weekly Paclitaxel
first-line palliative chemotherapy for advanced gallbladder cancer and
carboplatin (cont'd) injectable Gastrointestinal GIAVPG I
cholangiocarcinoma using gemcitabine and cisplatin
neoadjuvant treatment of esophageal and gastroesophageal carcinomas
carboplatin injectable Gastrointestinal GIENACTRT I
using carboplatin, paclitaxel and radiation therapy
alternative treatment of gynecological malignancies using carboplatin and
carboplatin (cont'd) injectable Gynecology GOCABR I
paclitaxel NAB (ABRAXANE)
alternative treatment of gynecological malignancies using bevacizumab,
carboplatin (cont'd) injectable Gynecology GOCABRBEV I
carboplatin and paclitaxel NAB (ABRAXANE)

* denotes change
Page 8 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment of advanced/recurrent non-small cell cancer of the cervix with
carboplatin (cont'd) injectable Gynecology GOCXCAD I
carboplatin and docetaxel
primary treatment of advanced/recurrent non-small cell cancer of the
carboplatin (cont'd) injectable Gynecology GOCXCAT I
cervix with carboplatin and paclitaxel
primary treatment of metastatic/recurrent cancer of the cervix with
carboplatin injectable Gynecology GOCXCATB I
bevacizumab, carboplatin and paclitaxel
treatment of primarily advanced or recurrent endometrial cancer using
carboplatin injectable Gynecology GOENDCAD I
carboplatin and docetaxel
treatment of primary advanced or recurrent endometrial cancer using
carboplatin (cont'd) injectable Gynecology GOENDCAT I
carboplatin and paclitaxel
primary treatment with visible or no visible residual tumour (moderate,
high, or extreme risk) or treatment at relapse of invasive epithelial ovarian,
carboplatin (cont'd) injectable Gynecology GOOVCAD I
fallopian tube, and primary peritoneal cancer, using carboplatin and
docetaxel
carboplatin and gemcitabine for the treatment of recurrent platinum-
carboplatin (cont'd) injectable Gynecology GOOVCAG I
sensitive ovarian cancer
first or second line therapy for invasive epithelial ovarian cancer using
carboplatin (cont'd) injectable Gynecology GOOVCARB I
single-agent carboplatin
primary treatment of invasive epithelial ovarian, fallopian tube and primary
carboplatin (cont'd) injectable Gynecology peritoneal cancer with high risk of relapse using bevacizumab, carboplatin GOOVCATB I
and paclitaxel
primary treatment of invasive epithelial ovarian, fallopian tube and primary
carboplatin (cont'd) injectable Gynecology peritoneal cancer, with no visible residual tumour (moderate-high risk) GOOVCATM I
using carboplatin and paclitaxel
second line treatment using paclitaxel and carboplatin for epithelial ovarian
carboplatin (cont'd) injectable Gynecology GOOVCATR I
cancer relapsing after primary treatment
primary treatment of visible residual (extreme risk) invasive epithelial
carboplatin (cont'd) injectable Gynecology ovarian cancer in ambulatory care settings using paclitaxel and GOOVCATX I
carboplatin

primary treatment of advanced epithelial ovarian, primary peritoneal, or


carboplatin (cont'd) injectable Gynecology GOOVDDCAT I
fallopian tube carcinoma using carboplatin and weekly paclitaxel

first line treatment of epithelial ovarian cancer using doxorubicin pegylated


carboplatin (cont'd) injectable Gynecology GOOVFPLDC I
liposomal and carboplatin

primary treatment of stage III less than or equal to 1 cm visible residual


invasive epithelial ovarian cancer or stage 1 grade 3 or stage II grade 3
carboplatin (cont'd) injectable Gynecology GOOVIPPC I
papillary serous ovarian cancer using intravenous and intraperitoneal
paclitaxel and intraperitoneal carboplatin

second line treatment for epithelial ovarian cancer relapsing after primary
carboplatin (cont'd) injectable Gynecology GOOVPLDC I
treatment using pegylated liposomal doxorubicin (PLD) and carboplatin

carboplatin (cont'd) injectable Gynecology treatment of small-cell gynecologic cancer with cisplatin and etoposide GOSCPE I

treatment of small-cell gynecologic cancer with cisplatin and etoposide


carboplatin (cont'd) injectable Gynecology GOSCPERT I
with radiation therapy

carboplatin (cont'd) injectable Genitourinary palliative therapy for urothelial carcinoma using cisplatin and gemcitabine GUAVPG I

* denotes change
Page 9 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
carboplatin (cont'd) injectable Genitourinary adjuvant therapy for stage I high risk seminoma using carboplatin GUSCARB I

carboplatin (cont'd) injectable Genitourinary therapy of genitourinary small cell tumors with a platin and etoposide GUSCPE I

therapy of genitourinary small cell tumors with a platin and etoposide with
carboplatin (cont'd) injectable Genitourinary GUSCPERT I
radiation
treatment of advanced squamous cell carcinoma of the head and neck
carboplatin (cont'd) injectable Head and Neck HNAVFUP I
cancer using fluorouracil and platinum
treatment for unresectable, locoregionally recurrent or metastatic
carboplatin (cont'd) injectable Head and Neck squamous cell carcinoma of the head and neck using paclitaxel and HNAVPC I
cisplatin or carboplatin

First-Line Treatment of Advanced Squamous Cell Carcinoma of the Head


carboplatin (cont'd) injectable Head and Neck UHNAVPCPMB R
and Neck with Paclitaxel, Carboplatin and Pembrolizumab

treatment of recurrent or metastatic squamous cell carcinoma of the head


carboplatin (cont'd) injectable Head and Neck HNAVPD I
and neck with platinum and docetaxel
treatment of recurrent and metastatic squamous cell cancer with platinum
carboplatin (cont'd) injectable Head and Neck HNAVPE I
and etoposide

First-Line Treatment of Advanced Squamous Cell Carcinoma of the Head


carboplatin (cont'd) injectable Head and Neck UHNAVPFPMB R
and Neck using Platinum, Fluorouracil and Pembrolizumab

combined chemotherapy (carboplatin and fluorouracil) and radiation


carboplatin (cont'd) injectable Head and Neck treatment for locally advanced squamous cell carcinoma of the head and HNLACAFRT I
neck
treatment of locally advanced squamous cell carcinoma of the head and
carboplatin (cont'd) injectable Head and Neck HNLACART I
neck with concurrent carboplatin and radiation
Treatment of Locally Advanced Squamous Cell Carcinoma of the Head
carboplatin (cont'd) injectable Head and Neck HNLACART3 I
and Neck with Concurrent 3-Weekly Carboplatin and Radiation
treatment for advanced nasopharyngeal cancer of the head and neck
carboplatin (cont'd) injectable Head and Neck HNNAVFUP I
using platinum and fluorouracil
treatment of recurrent and/or metastatic nasopharyngeal cancer with
carboplatin (cont'd) injectable Head and Neck HNNAVPE I
platinum and etoposide
treatment of locoregionally recurrent and/or metastatic nasopharyngeal
carboplatin (cont'd) injectable Head and Neck HNNAVPG I
cancer with platinum and gemcitabine
treatment of recurrent or metastatic nasopharyngeal carcinoma with
carboplatin (cont'd) injectable Head and Neck HNNAVPC I
carboplatin and paclitaxel
adjuvant carboplatin and paclitaxel following resection of stage I, II and
carboplatin (cont'd) injectable Lung LUAJPC I
IIIA non-small cell lung cancer
first-line treatment of advanced non-small cell lung cancer with carboplatin
carboplatin (cont'd) injectable Lung LUAVPC I
and paclitaxel
first-line treatment of advanced squamous non-small cell lung cancer with
carboplatin (cont'd) injectable Lung LUAVPCPMB I
paclitaxel, carboplatin and pembrolizumab
treatment of advanced non-small cell lung cancer with platinum and
carboplatin (cont'd) injectable Lung LUAVPG I
gemcitabine
first-line treatment of advanced squamous non-small cell lung cancer with
cisplatin (cont'd) injectable Lung LUAVPGPMB I
platinum, gemcitabine and pembrolizumab
first-line treatment of advanced non-small cell lung cancer with platinum
carboplatin (cont'd) injectable Lung LUAVPP I
and pemetrexed
first-line treatment of advanced non-squamous non-small cell lung cancer
carboplatin (cont'd) injectable Lung LUAVPPPMB I
with platinum, pemetrexed and pembrolizumab
treatment of locally advanced non-small cell lung cancer using carboplatin
carboplatin (cont'd) injectable Lung LULACATRT I
and paclitaxel with radiation therapy

* denotes change
Page 10 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment of locally advanced non-small cell lung cancer using cisplatin
carboplatin (cont'd) injectable Lung LULAPERT I
and etoposide with radiation therapy

treatment of locally advanced non-small cell lung cancer using alternative


carboplatin (cont'd) injectable Lung LULAPE2RT I
dosing of cisplatin and etoposide with radiation therapy

carboplatin (cont'd) injectable Lung treatment of thymoma with cisplatin and etoposide LUOTPE I

carboplatin (cont'd) injectable Lung treatment of thymoma using cisplatin and etoposide with radiation therapy LUOTPERT I

treatment of cancer of unknown primary involving the thorax with cisplatin


carboplatin (cont'd) injectable Lung LUPUPE I
and etoposide
therapy of extensive stage small cell lung cancer with cisplatin and
carboplatin (cont'd) injectable Lung LUSCPE I
etoposide
therapy of limited stage small cell lung cancer using cisplatin and
carboplatin (cont'd) injectable Lung LUSCPERT I
etoposide with radiation
second line treatment of extensive stage small cell lung cancer (SCLC)
carboplatin (cont'd) injectable Lung LUSCPI I
with irinotecan with or without platinum

treatment of relapsed or refractory advanced stage aggressive B-cell non-


carboplatin (cont'd) injectable Lymphoma LYRICE I
Hodgkin’s lymphoma with ifosfamide, carboplatin, etoposide and rituximab

primary treatment of cancer of unknown primary origin using carboplatin


carboplatin (cont'd) injectable Primary Unknown PUCAT I
and paclitaxel
treatment of recurrent or metastatic Merkel cell carcinoma with cisplatin
carboplatin (cont'd) injectable Skin & Melanoma SMMCCPE I
and etoposide

Other tumour site


Not Otherwise
carboplatin (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. HNNOS)

* denotes change
Page 11 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
therapy of multiple myeloma using carfilzomib and dexamethasone with or
carfilzomib injectable Myeloma UMYCARDEX R
without cyclophosphamide
therapy of multiple myeloma using carfilzomib, lenalidomide with
carfilzomib injectable Myeloma UMYCARLD R
dexamethasone
carmustine injectable Lymphoma topical therapy in cutaneous T-cell lymphoma LYCARTOP I

Other tumour site


Not Otherwise
carmustine injectable code followed by I
Specified
‘NOS’ (e.g. LKNOS)

cemiplimab injectable Skin & Melanoma Cemiplimab for Treatment of Cutaneous Squamous Cell Carcinoma SMAVCEM I
treatment of ALK-positive advanced non-small cell lung cancer (NSCLC)
ceritinib capsule Lung LUAVCER I
with ceritinib
palliative third line treatment of metastatic colorectal cancer with wild-type
cetuximab injectable Gastrointestinal GIAVCETIR I
KRAS using cetuximab and irinotecan
combined cetuximab and radiation treatment for locally advanced
cetuximab (cont'd) injectable Head and Neck HNLACETRT I
squamous cell carcinoma of the head and neck
chlorambucil tablet Lymphoma low grade lymphoma and chronic lymphocytic leukemia LYCHLOR I

chlorambucil tablet Lymphoma treatment of indolent B-cell lymphoma with chlorambucil and rituximab LYCHLRR I

chlorambucil tablet Lymphoma treatment of chronic lymphocytic leukemia with chlorambucil and rituximab LYCLLCHLR I

chlorambucil tablet Lymphoma lymphoma palliative chemotherapy LYPALL I


treatment of previously untreated chronic lymphocytic leukemia using
chlorambucil (cont'd) tablet Lymphoma LYOBCHLOR I
obinutuzumab in combination with chlorambucil
Other tumour site
Not Otherwise code followed by
chlorambucil (cont'd) tablet I
Specified ‘NOS’ (e.g. LKNOS,
LYNOS)

* denotes change
Page 12 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
palliative therapy for metastatic breast cancer using cisplatin and
cisplatin injectable Breast BRAVGEMP I
gemcitabine
adjuvant lomustine, cisplatin and vincristine in adult high-risk
cisplatin Neuro-Oncology CNCCV I
injectable medulloblastoma or other primitive neuroectodermal tumour
first-line palliative chemotherapy for advanced gallbladder cancer and
cisplatin Gastrointestinal GIAVPG I
injectable cholangiocarcinoma using gemcitabine and cisplatin
curative-intent combined modality therapy for cancer of the anal canal,
cisplatin GICPART I
injectable Gastrointestinal using cisplatin, capecitabine and radiation therapy
Note: cisplatin solution and
cisplatin powder (SAP) only funded
hepatic trans-arterial chemoembolization for primary liver cancer or liver
cisplatin (cont'd) injectable Gastrointestinal GIEMBOL I when prescribed by specialists at
metastasis
BC Cancer VC and Royal Jubilee
Hospital

palliative chemotherapy for upper gastrointestinal tract cancer (gastric,


cisplatin (cont'd) injectable Gastrointestinal esophageal, gall bladder carcinoma and cholangiocarcinoma) and GIFUC I
metastatic anal cancer using infusional fluorouracil and cisplatin

combined modality curative therapy for carcinoma of the anal canal using
cisplatin (cont'd) injectable Gastrointestinal GIFUPART I
cisplatin, infusional fluorouracil and radiation therapy
adjuvant chemotherapy of gastric cancer patients with completely
cisplatin (cont'd) injectable Gastrointestinal resected gastric cancer using cisplatin and capecitabine and radiation GIGAJCPRT I
therapy
palliative therapy of metastatic or locally advanced anal squamous cell
cisplatin (cont'd) injectable Gastrointestinal GIGAVCC I
carcinoma using cisplatin and capecitabine
Palliative Treatment of Metastatic or Locally Advanced Gastric,
cisplatin (cont'd) injectable Gastrointestinal Gastroesophageal Junction or Esophageal Adenocarcinoma using GIGAVCCT I
Cisplatin, Capecitabine and Trastuzumab
palliative treatment of metastatic or inoperable, locally advanced gastric or
cisplatin (cont'd) injectable Gastrointestinal gastroesophageal junction adenocarcinoma using cisplatin, infusional GIGAVCFT I
fluorouracil and trastuzumab
treatment of operable cancer of the stomach, stomach-esophagus
cisplatin (cont'd) injectable Gastrointestinal junction or lower 1/3 esophagus, given before and after surgery, using GIGECC I
epirubicin, cisplatin and capecitabine

cisplatin (cont'd) injectable Gastrointestinal palliative therapy of neuroendocrine tumours using cisplatin and etoposide GIPE I

hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with


cisplatin (cont'd) Gastrointestinal GIPMHIPEC I
peritoneal mesothelioma using doxorubicin, cisplatin and paclitaxel
injectable
therapy of non-dysgerminomatous ovarian germ cell cancer using
cisplatin (cont'd) injectable Gynecology GOBEP I
bleomycin, etoposide and cisplatin
alternative treatment of gynecological malignancies using cisplatin and
cisplatin (cont'd) injectable Gynecology GOCISP I
paclitaxel

* denotes change
Page 13 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
Alternative Treatment of Gynecological Malignancies using Bevacizumab,
cisplatin (cont'd) injectable Gynecology GOCISPBEV I
Cisplatin and Paclitaxel
treatment of high risk squamous carcinoma, adenocarcinoma, or
cisplatin (cont'd) injectable Gynecology adenosquamous carcinoma of the cervix with concurrent cisplatin and GOCXCRT I
radiation
therapy of dysgerminomatous ovarian germ cell cancer using cisplatin and
cisplatin (cont'd) injectable Gynecology GOEP I
etoposide
cisplatin (cont'd) injectable Gynecology invasive epithelial ovarian cancer GOOVCIS I

cisplatin (cont'd) injectable Gynecology treatment of small-cell gynecologic cancer with cisplatin and etoposide GOSCPE I

treatment of small-cell gynecologic cancer with cisplatin and etoposide


cisplatin (cont'd) injectable Gynecology GOSCPERT I
with radiation therapy

cisplatin (cont'd) injectable Genitourinary adjuvant therapy for urothelial carcinoma using cisplatin and gemcitabine GUAJPG I

cisplatin (cont'd) injectable Genitourinary palliative therapy for urothelial carcinoma using cisplatin and gemcitabine GUAVPG I

curative therapy for germ cell cancer using bleomycin, etoposide and
cisplatin (cont'd) injectable Genitourinary GUBEP I
cisplatin
treatment of locally advanced bladder cancer with weekly cisplatin and
cisplatin (cont'd) injectable Genitourinary GUBPWRT I
concurrent radiation
treatment of metastatic adrenalcortical cancer with doxorubicin, etoposide,
cisplatin (cont'd) injectable Genitourinary GUEDPM I
cisplatin and mitotane

cisplatin (cont'd) injectable Genitourinary therapy for nonseminoma germ cell cancer using etoposide-cisplatin GUEP I

combined modality therapy for squamous cell cancer of the genitourinary


cisplatin (cont'd) injectable Genitourinary GUFUPRT I
system using fluorouracil and cisplatin with radiation
therapy for transitional cell cancers of the urothelium using methotrexate,
cisplatin (cont'd) injectable Genitourinary GUMVAC I
vinblastine, doxorubicin and cisplatin
neo-adjuvant therapy for urothelial carcinoma using cisplatin and
cisplatin (cont'd) injectable Genitourinary GUNAJPG I
gemcitabine

cisplatin (cont'd) injectable Genitourinary therapy of genitourinary small cell tumors with a platin and etoposide GUSCPE I

therapy of genitourinary small cell tumors with a platin and etoposide with
cisplatin (cont'd) injectable Genitourinary GUSCPERT I
radiation
advanced therapy for relapsed testicular germ cell cancer using paclitaxel,
cisplatin (cont'd) injectable Genitourinary GUTIP I
ifosfamide and cisplatin
consolidation/ salvage treatment for germ cell cancer using vinblastine,
cisplatin (cont'd) injectable Genitourinary GUVEIP I
cisplatin, ifosfamide and mesna
nonseminoma consolidation/salvage protocol using etoposide, cisplatin,
cisplatin (cont'd) injectable Genitourinary GUVIP2 I
ifosfamide, mesna
treatment of advanced squamous cell carcinoma of the head and neck
cisplatin (cont'd) injectable Head and Neck HNAVFUP I
cancer using fluorouracil and platinum
palliative chemotherapy for advanced head and neck squamous cell
cisplatin (cont'd) injectable Head and Neck HNAVP I
carcinoma with weekly cisplatin
treatment for unresectable, locoregionally recurrent or metastatic
cisplatin (cont'd) injectable Head and Neck squamous cell carcinoma of the head and neck using paclitaxel and HNAVPC I
cisplatin or carboplatin

* denotes change
Page 14 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment of recurrent or metastatic squamous cell carcinoma of the head
cisplatin (cont'd) injectable Head and Neck HNAVPD I
and neck with platinum and docetaxel
treatment of recurrent and metastatic squamous cell cancer with platinum
cisplatin (cont'd) injectable Head and Neck HNAVPE I
and etoposide

First-Line Treatment of Advanced Squamous Cell Carcinoma of the Head


cisplatin (cont'd) injectable Head and Neck UHNAVPFPMB R
and Neck using Platinum, Fluorouracil and Pembrolizumab

treatment of locally advanced (alternate) head and neck cancer using


cisplatin (cont'd) injectable Head and Neck HNLAALTPRT I
cisplatin during radiation therapy
treatment of locally advanced squamous cell carcinoma of the head and
cisplatin (cont'd) injectable Head and Neck HNLADCF I
neck with docetaxel, cisplatin and infusional fluorouracil
combined chemotherapy (cisplatin) and radiation treatment for locally
cisplatin (cont'd) injectable Head and Neck HNLAPRT I
advanced squamous cell carcinoma of the head and neck
treatment for advanced nasopharyngeal cancer of the head and neck
cisplatin (cont'd) injectable Head and Neck HNNAVFUP I
using platinum and fluorouracil
palliative chemotherapy for advanced head and neck nasopharyngeal
cisplatin (cont'd) injectable Head and Neck HNNAVP I
carcinoma with weekly cisplatin
treatment of recurrent and/or metastatic nasopharyngeal cancer with
cisplatin (cont'd) injectable Head and Neck HNNAVPE I
platinum and etoposide
treatment of locoregionally recurrent and/or metastatic nasopharyngeal
cisplatin (cont'd) injectable Head and Neck HNNAVPG I
cancer with platinum and gemcitabine
induction treatment of locally advanced nasopharyngeal cancer with
cisplatin (cont'd) injectable Head and Neck HNNLAPG I
cisplatin and gemcitabine
treatment of locally advanced nasopharyngeal cancer with concurrent
cisplatin (cont'd) injectable Head and Neck HNNLAPRT I
cisplatin and radiation
treatment of advanced head and neck cancer using cisplatin and
cisplatin (cont'd) injectable Head and Neck HNSAVFUP I
fluorouracil
treatment of advanced salivary gland cancers with cisplatin and
cisplatin (cont'd) injectable Head and Neck HNSAVNP I
vinorelbine
treatment of advanced salivary gland cancers with platinum, doxorubicin
cisplatin (cont'd) injectable Head and Neck HNSAVPAC I
and cyclophospahmide
adjuvant cisplatin and vinorelbine following resection of non-small cell lung
cisplatin (cont'd) injectable Lung LUAJNP I
cancer
Adjuvant Cisplatin and Pemetrexed Following Resection of Non-Small Cell
cisplatin (cont'd) injectable Lung LUAJPP I
Lung Cancer
first-line treatment of advanced non-small cell lung cancer with cisplatin
cisplatin (cont'd) injectable Lung LUAVDC I
and docetaxel
treatment for advanced non-small cell lung cancer with cisplatin and
cisplatin (cont'd) injectable Lung LUAVNP I
vinorelbine
treatment of advanced non-small cell lung cancer with platinum and
cisplatin (cont'd) injectable Lung LUAVPG I
gemcitabine
first-line treatment of advanced squamous non-small cell lung cancer with
cisplatin (cont'd) injectable Lung LUAVPGPMB I
platinum, gemcitabine and pembrolizumab
first-line treatment of advanced non-small cell lung cancer with platinum
cisplatin (cont'd) injectable Lung LUAVPP I
and pemetrexed
first-line treatment of advanced non-squamous non-small cell lung cancer
cisplatin (cont'd) injectable Lung LUAVPPPMB I
with platinum, pemetrexed and pembrolizumab
treatment of locally advanced non-small cell lung cancer using cisplatin
cisplatin (cont'd) injectable Lung LULAPERT I
and etoposide with radiation therapy

* denotes change
Page 15 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES

treatment of locally advanced non-small cell lung cancer using alternative


cisplatin (cont'd) injectable Lung LULAPE2RT I
dosing of cisplatin and etoposide with radiation therapy

cisplatin (cont'd) injectable Lung treatment of malignant mesothelioma with platinum and gemcitabine LUMMPG I

cisplatin (cont'd) injectable Lung treatment of malignant mesothelioma with platinum and pemetrexed LUMMPP I

cisplatin (cont'd) injectable Lung treatment of thymoma with platinum, doxorubicin and cyclophosphamide LUOTPAC I

cisplatin (cont'd) injectable Lung treatment of thymoma with cisplatin and etoposide LUOTPE I

cisplatin (cont'd) injectable Lung treatment of thymoma using cisplatin and etoposide with radiation therapy LUOTPERT I

treatment of cancer of unknown primary involving the thorax with cisplatin


cisplatin (cont'd) injectable Lung LUPUPE I
and etoposide
therapy of extensive stage small cell lung cancer with cisplatin and
cisplatin (cont'd) injectable Lung LUSCPE I
etoposide
therapy of limited stage small cell lung cancer using cisplatin and
cisplatin (cont'd) injectable Lung LUSCPERT I
etoposide with radiation
second line treatment of extensive stage small cell lung cancer (SCLC)
cisplatin (cont'd) injectable Lung LUSCPI I
with irinotecan with or without platinum

cisplatin (cont'd) injectable Lymphoma treatment of lymphoma with gemcitabine, dexamethasone and platinum LYGDP I

treatment of lymphoma with gemcitabine, dexamethasone and platinum


cisplatin (cont'd) injectable Lymphoma LYGDPR I
with rituximab

Treatment of newly diagnosed nasal, extranodal natural killer (NK) or T-


cisplatin (cont'd) injectable Lymphoma cell lymphoma, stage IE to IIE using concurrent radiation and weekly LYVIPDRT I
cisplatin followed by etoposide, ifosfamide, cisplatin and dexamethasone

cisplatin (cont'd) injectable Sarcoma adjuvant therapy for osteosarcoma using doxorubicin and cisplatin SAAJAP I

cisplatin (cont'd) injectable Sarcoma therapy of advanced osteosarcoma using doxorubicin and cisplatin SAAVAP I

hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with


cisplatin (cont'd) injectable Sarcoma SAHIPEC I
peritoneal desmoplastic small round cell tumour (DSRCT)
treatment of recurrent or metastatic Merkel cell carcinoma with cisplatin
cisplatin (cont'd) injectable Skin & Melanoma SMMCCPE I
and etoposide
Other tumour site
Not Otherwise
cisplatin (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. HNNOS)
cladribine injectable Lymphoma hairy cell leukemia LYCDA I
bony metastases associated with breast cancer or acute bone pain
clodronate capsule Breast BRAVCLOD I Not reimbursed for hypercalcemia
secondary to metastatic breast cancer
treatment of BRAF V600 mutation-positive unresectable or metastatic
cobimetinib tablet Skin & Melanoma SMAVVC I
melanoma using vemurafenib and cobimetinib
treatment of metastatic adrenalcortical cancer with doxorubicin, etoposide,
cortisone tablet Genitourinary GUEDPM I
cisplatin and mitotane
cortisone tablet Genitourinary treatment of adrenal cortical cancer using mitotane GUMITO I
Other tumour site
Not Otherwise
cortisone tablet code followed by I
Specified
‘NOS’ (e.g. GUNOS)

* denotes change
Page 16 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
second-line treatment of ALK-positive advanced non-small cell lung
crizotinib tablet Lung LUAVCRIZ I
cancer (NSCLC) with crizotinib
first-line treatment of ALK-positive advanced non-small cell lung cancer
crizotinib (cont'd) tablet Lung LUAVCRIZF I
(NSCLC) with crizotinib
first-line treatment of ROS1-positive advanced non-small cell lung cancer
crizotinib (cont'd) tablet Lung LUAVCRIZR I
with crizotinib
myeloablative conditioning therapy prior to autologous and allogeneic
cyclophosphamide tablet, injectable Leukemia & BMT hematopoietic stem cell transplantation for myeloid malignancies using IV BMTIVBUCY I
busulfan and cyclophosphamide
adjuvant therapy for breast cancer using doxorubicin and
cyclophosphamide tablet, injectable Breast BRAJAC I
cyclophosphamide
neoadjuvant or adjuvant therapy for breast cancer using doxorubicin and
cyclophosphamide (cont'd) tablet, injectable Breast BRAJACT I
cyclophosphamide followed by paclitaxel

neoadjuvant or adjuvant therapy for breast cancer using dose dense


cyclophosphamide (cont'd) tablet, injectable Breast BRAJACTG I
therapy: doxorubicin and cyclophosphamide followed by paclitaxel

neoadjuvant or adjuvant therapy for breast cancer using doxorubicin and


cyclophosphamide (cont'd) tablet, injectable Breast BRAJACTT I
cyclophosphamide followed by paclitaxel and trastuzumab

neoadjuvant or adjuvant therapy for breast cancer using dose dense


cyclophosphamide tablet, injectable Breast therapy: doxorubicin and cyclophosphamide followed by paclitaxel and BRAJACTTG I
trastuzumab
neoadjuvant or adjuvant therapy for early breast cancer using doxorubicin
cyclophosphamide (cont'd) tablet, injectable Breast BRAJACTW I
and cyclophosphamide followed by weekly paclitaxel
adjuvant therapy for high-risk breast cancer using cyclophosphamide
cyclophosphamide (cont'd) tablet, injectable BRAJCMFPO I
Breast (oral), methotrexate and fluorouracil
neoadjuvant or adjuvant therapy for breast cancer using
cyclophosphamide (cont'd) tablet, injectable BRAJDAC I
Breast cyclophosphamide, doxorubicin and docetaxel
neoadjuvant or adjuvant therapy for breast cancer using docetaxel and
cyclophosphamide (cont'd) tablet, injectable Breast BRAJDC I
cyclophosphamide
adjuvant therapy for breast cancer using fluorouracil, epirubicin and
cyclophosphamide (cont'd) tablet, injectable Breast BRAJFEC I
cyclophosphamide
neoadjuvant or adjuvant therapy for breast cancer using fluorouracil,
cyclophosphamide (cont'd) tablet, injectable Breast BRAJFECD I
epirubicin and cyclophosphamide and docetaxel

neoadjuvant or adjuvant therapy for breast cancer using fluorouracil,


cyclophosphamide (cont'd) tablet, injectable BRAJFECDT I
epirubicin and cyclophosphamide followed by docetaxel and trastuzumab
Breast
neoadjuvant or adjuvant therapy for breast cancer using trastuzumab,
cyclophosphamide (cont'd) tablet, injectable Breast BRAJTDC I
docetaxel and cyclophosphamide
palliative therapy for metastatic breast cancer using doxorubicin and
cyclophosphamide (cont'd) tablet, injectable Breast BRAVAC I
cyclophosphamide
palliative therapy for advanced breast cancer using cyclophosphamide,
cyclophosphamide (cont'd) tablet, injectable BRAVCMF I
Breast methotrexate and fluorouracil
palliative therapy for metastatic breast cancer using metronomic low-dose
cyclophosphamide (cont'd) tablet, injectable Breast BRAVCMPO I
oral cyclophosphamide and methotrexate
treatment of locally advanced breast cancer using doxorubicin and
cyclophosphamide (cont'd) tablet, injectable Breast BRLAACD I
cyclophosphamide followed by docetaxel

* denotes change
Page 17 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment of locally advanced breast cancer using doxorubicin and
cyclophosphamide (cont'd) tablet, injectable Breast BRLAACDT I
cyclophosphamide followed by docetaxel and trastuzumab

neoadjuvant therapy for triple-negative breast cancer using carboplatin


cyclophosphamide (cont'd) injectable Breast BRLACTWAC I
and weekly paclitaxel followed by doxorubicin and cyclophosphamide

Neoadjuvant Therapy for Triple-Negative Breast Cancer using Dose-


cyclophosphamide (cont'd) injectable Breast Dense Therapy: Carboplatin and Weekly Paclitaxel Followed by BRLACTWACG I
Doxorubicin and Cyclophosphamide

neoadjuvant therapy for breast cancer using dose dense therapy:


cyclophosphamide (cont'd) injectable Breast BRLATACG I
paclitaxel followed by doxorubicin and cyclophosphamide

treatment of locally advanced breast cancer using doxorubicin and


cyclophosphamide (cont'd) injectable Breast BRLATWAC I
cyclophosphamide followed by weekly paclitaxel
palliative therapy for relapsed/progressing epithelial ovarian, primary
cyclophosphamide (cont'd) tablet, injectable Gynecology peritoneal, or fallopian tube carcinoma using metronomic low-dose oral GOOVCYCPO I
cyclophosphamide
therapy for high-risk Gestational Trophoblastic Neoplasia (GTN) using
cyclophosphamide (cont'd) tablet, injectable Gynecology etoposide, methotrexate, leucovorin (folinic acid), dactinomycin, GOTDEMACO I
cyclophosphamide and vincristine
palliative therapy for advanced salivary gland cancers using
cyclophosphamide (cont'd) tablet, injectable Head and Neck HNSAVFAC I
cyclophosphamide, doxorubicin and fluorouracil
treatment of advanced salivary gland cancers with platinum, doxorubicin
cyclophosphamide (cont'd) tablet, injectable Head and Neck HNSAVPAC I
and cyclophospahmide
treatment of thymoma/thymic carcinoma with cyclophosphamide,
cyclophosphamide (cont'd) tablet, injectable Lung LUOTCAV I
doxorubicin and vincristine

cyclophosphamide (cont'd) tablet, injectable Lung treatment of thymoma with platinum, doxorubicin and cyclophosphamide LUOTPAC I

treatment of extensive small cell lung cancer with cyclophosphamide,


cyclophosphamide (cont'd) tablet, injectable Lung LUSCCAV I
doxorubicin and vincristine
treatment of lymphoma with doxorubicin, cyclophosphamide, vincristine
cyclophosphamide (cont'd) tablet, injectable Lymphoma LYCHOP I
and prednisone
treatment of lymphoma with doxorubicin, cyclophosphamide, vincristine,
cyclophosphamide (cont'd) tablet, injectable Lymphoma LYCHOPR I
prednisone and rituximab
treatment of CD30-positive peripheral T-Cell Lymphoma (PTCL) with
cyclophosphamide (cont'd) tablet, injectable Lymphoma doxorubicin, cyclophosphamide, prednisone (CHP) and brentuximab LYCHPBV I
vedotin
treatment of relapsed chronic lymphocytic leukemia using
cyclophosphamide (cont'd) tablet, injectable Lymphoma LYCLLCVPR I
cyclophosphamide, vincristine, prednisone and rituximab

treatment of Burkitt’s Lymphoma and Leukemia with cyclophosphamide,


cyclophosphamide (cont'd) tablet, injectable Lymphoma LYCODOXMR I
vincristine, doxorubicin, methotrexate, leucovorin and rituximab

advanced indolent lymphoma using cyclophosphamide, vincristine and


cyclophosphamide (cont'd) tablet, injectable Lymphoma LYCVP I
prednisone
treatment of Hodgkin's disease with cyclophosphamide, vinblastine,
cyclophosphamide (cont'd) tablet, injectable Lymphoma LYCVPPABO I
procarbazine and prednisone
treatment of advanced indolent lymphoma using cyclophosphamide,
cyclophosphamide (cont'd) tablet, injectable Lymphoma LYCVPR I
vincristine, prednisone and rituximab
therapy of lymphoma, Hodgkin's disease, chronic lymphocytic leukemia or
cyclophosphamide (cont'd) tablet, injectable Lymphoma LYCYCLO I
multiple myeloma using cyclophosphamide

* denotes change
Page 18 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment of lymphoma with dose-adjusted etoposide, doxorubicin,
cyclophosphamide (cont'd) tablet, injectable Lymphoma vincristine, cyclophosphamide, prednisone and rituximab with intrathecal LYEPOCHR I
methotrexate

treatment of chronic lymphocytic leukemia (CLL) or prolymphocytic


cyclophosphamide (cont'd) tablet, injectable Lymphoma LYFCR I
leukemia with fludarabine, cyclophosphamide and rituximab

cyclophosphamide (cont'd) tablet, injectable Lymphoma lymphoma palliative chemotherapy LYPALL I

treatment of multiple myeloma using bortezomib, dexamethasone with or


cyclophosphamide (cont'd) tablet, injectable Myeloma MYBORPRE I
without cyclophosphamide as induction pre-stem cell transplant

treatment of relapsed multiple myeloma using bortezomib,


cyclophosphamide (cont'd) tablet, injectable Myeloma MYBORREL I
dexamethasone with or without cyclophosphamide
therapy of multiple myeloma using carfilzomib and dexamethasone with or
cyclophosphamide (cont'd) tablet, injectable Myeloma UMYCARDEX R
without cyclophosphamide
treatment of relapsed and refractory multiple myeloma with daratumumab
cyclophosphamide (cont'd) tablet, injectable Myeloma in combination with bortezomib and dexamethasone with or without UMYDARBD R
cyclophosphamide
treatment of multiple myeloma using melphalan, prednisone and weekly
cyclophosphamide (cont'd) tablet, injectable Myeloma bortezomib with the option of substituting cyclophosphamide for MYMPBOR I
melphalan
single dose cyclophosphamide priming therapy for multiple myeloma prior
cyclophosphamide (cont'd) tablet, injectable Myeloma MYHDC I
to autologous stem cell transplant
SAIME alternating with SAVAC or SAVACM with filgrastim support at
TWO weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
cyclophosphamide (cont'd) tablet, injectable Sarcoma SAALT2W I
Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma
SAIME alternating with SAVAC or SAVACM with filgrastim support at
THREE weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
cyclophosphamide (cont'd) tablet, injectable Sarcoma SAALT3W I
Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma
summary for treatment of recurrent/refractory neuroblastoma, ewing’s
cyclophosphamide (cont'd) tablet, injectable Sarcoma sarcoma, osteogenic sarcoma or rhabdomyosarcoma with SAAVTC I
topotecan/cyclophosphamide

cyclophosphamide (cont'd) tablet, injectable Sarcoma treatment of sarcomas with vincristine, doxorubicin and cyclophosphamide SAVAC I

Treatment of Sarcomas with Pelvic Primaries or Chemotherapy-Induced


cyclophosphamide (cont'd) tablet, injectable Sarcoma SAVACM I
Hematuria using Vincristine, Doxorubicin, Cyclophosphamide and Mesna

Adjuvant Therapy for Rhabdomyosarcoma using Vincristine, Dactinomycin


cyclophosphamide (cont'd) tablet, injectable Sarcoma SAVDC I
and Cyclophosphamide
treatment of recurrent/refractory rhabdomysarcoma in pediatric patients
cyclophosphamide (cont'd) tablet, injectable Pediatric with cyclophosphamide, vinorelbine and temsirolimus on the COG I
ARST0921 protocol

Other tumour site


Not Otherwise
cyclophosphamide (cont'd) tablet, injectable code followed by I
Specified
‘NOS’ (e.g. BRNOS)

* denotes change
Page 19 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
cytopenias associated with lymphoproliferative disorder of large granular
cyclosporine capsule Lymphoma LYCSPA I
lymphocytes
treatment of hemophagocytic lymphohistiocytosis with etoposide,
cyclosporine capsule Lymphoma HLHETCSPA I
dexamethasone and cyclosporine
cytarabine injectable Leukemia & BMT therapy of acute myeloid leukemia using low dose cytarabine LKAMLCYT I
Treatment of Acute Myeloid Leukemia using Gemtuzumab Ozogamicin
cytarabine injectable Leukemia & BMT ULKGEMOZ R
with Induction and Consolidation Chemotherapy

treatment of Burkitt’s lymphoma and leukemia with cyclophosphamide,


cytarabine injectable Lymphoma LYCODOXMR I
vincristine, doxorubicin, methotrexate, leucovorin and rituximab

cytarabine injectable Lymphoma treatment of lymphoma using intrathecal methotrexate and cytarabine LYIT I

treatment of Burkitt’s lymphoma and leukemia with ifosfamide, mesna,


cytarabine (cont'd) injectable Lymphoma LYIVACR I
etoposide, cytarabine and rituximab
therapy for solid tumours using intrathecal methotrexate and/or thiotepa
cytarabine (cont'd) injectable Miscellaneous Origins MOIT I
and/or cytarabine

Other tumour site


Not Otherwise
cytarabine (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. LYNOS)

* denotes change
Page 20 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
adjuvant treatment of stage III and IV, BRAF-mutated, fully resected
dabrafenib capsule Skin & Melanoma SMAJDT I
melanoma using dabrafenib and trametinib
treatment of BRAF V600 mutation-positive unresectable or metastatic
dabrafenib capsule Skin & Melanoma SMAVDAB I
melanoma using dabrafenib
treatment of BRAF V600 mutation-positive unresectable or metastatic
dabrafenib capsule Skin & Melanoma SMAVDT I
melanoma using dabrafenib and trametinib
treatment of Hodgkin's disease with doxorubicin, bleomycin, vinblastine
dacarbazine injectable Lymphoma LYABVD I
and dacarbazine

Treatment of Previously Untreated, Stage IV Hodgkin Lymphoma with


dacarbazine (cont'd) injectable Lymphoma LYAVDBV I
Doxorubicin, Vinblastine, Dacarbazine and Brentuximab Vedotin

adjuvant treatment of patients with soft tissue sarcoma using doxorubicin


dacarbazine (cont'd) injectable Sarcoma SAAJADIC I
and dacarbazine
treatment of patients with soft tissue sarcoma using doxorubicin and
dacarbazine injectable Sarcoma SAAVADIC I
dacarbazine

dacarbazine (cont'd) injectable Sarcoma high dose single agent dacarbazine for metastatic soft tissue sarcoma SADTIC I

therapy for metastatic malignant melanoma using high dose single agent
dacarbazine injectable Skin & Melanoma SMDTIC I
dacarbazine

Other tumour site


Not Otherwise
dacarbazine (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. SMNOS)

therapy for high-risk Gestational Trophoblastic Neoplasia (GTN) using


dactinomycin injectable Gynecology etoposide, methotrexate, leucovorin (folinic acid), dactinomycin, GOTDEMACO I
cyclophosphamide and vincristine

Therapy for Moderate Low-Risk Gestational Trophoblastic Cancer using GOTDMR (previously
dactinomycin (cont'd) injectable Gynecology I
Dactinomycin and Methotrexate GOTDLR)

Therapy for Low-Risk Gestational Trophoblastic Cancer using


dactinomycin (cont'd) injectable Gynecology GOTDLRA I
Dactinomycin
Adjuvant Therapy for Rhabdomyosarcoma using Vincristine, Dactinomycin
dactinomycin injectable Sarcoma SAVDC I
and Cyclophosphamide

Other tumour site


Not Otherwise
dactinomycin injectable code followed by I
Specified
‘NOS’ (e.g. SANOS)

treatment of relapsed and refractory multiple myeloma with daratumumab


daratumumab injectable Myeloma in combination with bortezomib and dexamethasone with or without UMYDARBD R
cyclophosphamide

treatment of relapsed and refractory multiple myeloma with daratumumab


daratumumab injectable Myeloma UMYDARLD R
in combination with lenalidomide and dexamethasone

Treatment of Non-Metastatic Castration-Resistant Prostate Cancer using


darolutamide tablet Genitourinary UGUNMPDAR R
Darolutamide
treatment of chronic myeloid leukemia and Ph+ acute lymphoblastic
dasatinib tablet Leukemia & BMT LKCMLD I
leukemia

* denotes change
Page 21 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES

first-line induction and consolidation therapy of acute promyelocytic


daunorubicin injectable Leukemia & BMT LKATOP I
leukemia using arsenic trioxide, tretinoin and daunorubicin

Treatment of Acute Myeloid Leukemia using Gemtuzumab Ozogamicin


daunorubicin injectable Leukemia & BMT ULKGEMOZ R
with Induction and Consolidation Chemotherapy

Other tumour site


Not Otherwise
daunorubicin injectable code followed by I
Specified
‘NOS’ (e.g. KSNOS)

degarelix injectable Genitourinary therapy for prostate cancer using LHRH antagonist GUPLHRHA I
neoadjuvant use in patients with non-metastatic operable giant cell tumour
denosumab (XGEVA®) injectable Sarcoma SANADENO I
of the bone
Therapy for Metastatic Castration-Sensitive Prostate Cancer using
dexamethasone tablet Genitourinary UGUMCSPABI R
Abiraterone and Prednisone
Palliative Therapy for Metastatic Castration Resistant Prostate Cancer
dexamethasone tablet Genitourinary UGUPABI R
Using Abiraterone and prednisone

palliative therapy for metastatic hormone refractory prostate cancer GUPDOC I

treatment of hemophagocytic lymphohistiocytosis with etoposide,


dexamethasone tablet Lymphoma HLHETCSPA I
dexamethasone and cycloSPORINE

treatment of refractory or relapsing extranodal natural killer or T-Cell


dexamethasone tablet Lymphoma LYASPMEDEX I
lymphoma using pegaspargase, methotrexate and dexamethasone

dexamethasone (cont'd) tablet Lymphoma treatment of lymphoma with gemcitabine, dexamethasone and platinum LYGDP I
treatment of lymphoma with gemcitabine, dexamethasone and platinum
dexamethasone Lymphoma LYGDPR I
tablet with rituximab

dexamethasone (cont'd) Lymphoma lymphoma palliative chemotherapy LYPALL I


tablet

treatment of natural killer or T-Cell Lymphoma using dexamethasone,


dexamethasone Lymphoma LYSMILE I
methotrexate, ifosfamide, pegaspargase and etoposide
tablet

treatment of newly diagnosed nasal, extranodal natural killer (NK) or T-cell Not reimbursed for:
dexamethasone (cont'd) tablet Lymphoma lymphoma, stage IE to IIE using concurrent radiation and weekly cisplatin LYVIPDRT I anti-emetic treatment, steroid
followed by etoposide, ifosfamide, cisplatin and dexamethasone replacement therapy, pre-taxane
use, or appetite stimulation
Bortezomib, Lenalidomide and Dexamethasone for Previously Untreated
dexamethasone (cont'd) tablet Myeloma UMYBLDF R
Multiple Myeloma

treatment of multiple myeloma using bortezomib, dexamethasone with or


dexamethasone (cont'd) tablet Myeloma MYBORPRE I
without cyclophosphamide as induction pre-stem cell transplant

treatment of relapsed multiple myeloma using bortezomib,


dexamethasone MYBORREL I
tablet Myeloma dexamethasone with or without cyclophosphamide
therapy of multiple myeloma using carfilzomib and dexamethasone with or
dexamethasone (cont'd) UMYCARDEX R
tablet Myeloma without cyclophosphamide
therapy of multiple myeloma using carfilzomib, lenalidomide with
dexamethasone (cont'd) tablet Myeloma UMYCARLD R
dexamethasone
treatment of relapsed and refractory multiple myeloma with daratumumab
dexamethasone in combination with bortezomib and dexamethasone with or without UMYDARBD R
tablet Myeloma cyclophosphamide

* denotes change
Page 22 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES

treatment of relapsed and refractory multiple myeloma with daratumumab


dexamethasone (cont'd) tablet Myeloma UMYDARLD R
in combination with lenalidomide and dexamethasone

treatment of previously untreated multiple myeloma and not eligible for


dexamethasone UMYLDF R
stem cell transplant using lenalidomide with low-dose dexamethasone
tablet Myeloma
therapy of relapsed multiple myeloma using lenalidomide with
dexamethasone (cont'd) tablet Myeloma UMYLDREL R
dexamethasone
treatment of multiple myeloma using melphalan, prednisone and weekly
dexamethasone (cont'd) bortezomib with the option of substituting cyclophosphamide for MYMPBOR I
tablet Myeloma melphalan

dexamethasone therapy of multiple myeloma using pomalidomide with dexamethasone UMYPOMDEX R


tablet Myeloma
patients with primary or metastatic disease exhibiting cerebral edema or Not reimbursed for:
dexamethasone (cont'd) tablet Miscellaneous Origins CNS swelling; management of malignant brain tumours; management of MODEXA I anti-emetic treatment, steroid
CNS lymphoma replacement therapy, pre-taxane
Other tumour site use, or appetite stimulation
Not Otherwise code followed by
dexamethasone (cont'd) tablet I
Specified ‘NOS’ (for e.g.
CNNOS)

Other tumour site


Not Otherwise
dexamethasone (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. BRNOS)

pediatric patients with acute myeloid leukemia receiving anthracycline on


dexrazoxane injectable Pediatric I
the COG AAML1031 protocol
pediatric patients with neuroblastoma treated on the CCG AEWS1031
dexrazoxane injectable Pediatric I
protocol
pediatric patients with rhabdomyosarcoma treated on the COG
dexrazoxane (cont'd) injectable Pediatric I
ARST08P1 protocol
treatment of pediatric patients with high-risk neuroblastoma who achieve a
dinutuximab injectable Pediatric response to prior first-line multi-agent, multimodal therapy using R
dinutuximab in combination with sargramostim, aldesleukin and tretinoin
neoadjuvant or adjuvant therapy for breast cancer using
docetaxel injectable Breast BRAJDAC I
cyclophosphamide, doxorubicin and docetaxel
neoadjuvant or adjuvant therapy for breast cancer using docetaxel and
docetaxel (cont'd) injectable Breast BRAJDC I
cyclophosphamide
neoadjuvant or adjuvant therapy for breast cancer using carboplatin,
docetaxel (cont'd) injectable Breast BRAJDCARBT I
docetaxel and trastuzumab
neoadjuvant or adjuvant therapy for breast cancer using fluorouracil,
docetaxel (cont'd) injectable Breast BRAJFECD I
epirubicin and cyclophosphamide and docetaxel

neoadjuvant or adjuvant therapy for breast cancer using fluorouracil,


docetaxel (cont'd) injectable Breast BRAJFECDT I
epirubicin and cyclophosphamide followed by docetaxel and trastuzumab

neoadjuvant or adjuvant therapy for breast cancer using trastuzumab,


docetaxel (cont'd) injectable Breast BRAJTDC I
docetaxel and cyclophosphamide
combination with doxorubicin and cyclophosphamide as treatment of
docetaxel (cont'd) injectable Breast BRLAACD I
locally advanced breast cancer

* denotes change
Page 23 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment of locally advanced breast cancer using doxorubicin and
docetaxel (cont'd) injectable Breast BRLAACDT I
cyclophosphamide followed by docetaxel and trastuzumab
first, second, or third line treatment of metastatic breast cancer patients
docetaxel (cont'd) injectable Breast with ECOG performance status 0, 1, or 2, and greater than 3 month life BRAVDOC I
expectancy
weekly docetaxel regimen for metastatic breast cancer patients with poor
docetaxel (cont'd) injectable Breast tolerance to 3-weekly docetaxel regimen (BRAVDOC) or high doses of BRAVDOC7 I
dexamethasone used in BRAVDOC
palliative therapy for metastatic breast cancer using gemcitabine and
docetaxel (cont'd) injectable Breast BRAVGEMD I
docetaxel
palliative therapy for metastatic breast cancer using pertuzumab,
docetaxel (cont'd) injectable Breast trastuzumab (Herceptin®) and docetaxel as first-line treatment for BRAVPTRAD I
advanced breast cancer
palliative treatment of metastatic esophagogastric adenocarcinoma with
docetaxel (cont'd) injectable Gastrointestinal GIAVDOC I
docetaxel
perioperative treatment of resectable adenocarcinoma of the stomach,
docetaxel (cont'd) injectable Gastrointestinal gastroesophageal junction or lower 1/3 esophagus using docetaxel, GIGFLODOC I
oxaliplatin, infusional fluorouracil, and leucovorin

combination with carboplatin as primary treatment of advanced/recurrent


docetaxel (cont'd) injectable Gynecology GOCXCAD I
non-small cell cancer of the cervix in ambulatory care settings

treatment of primarily advanced or recurrent endometrial cancer using


docetaxel (cont'd) injectable Gynecology GOENDCAD I
carboplatin and docetaxel
primary treatment with visible or no visible residual tumour (moderate,
high, or extreme risk) or treatment at relapse of invasive epithelial ovarian,
docetaxel (cont'd) injectable Gynecology GOOVCAD I
fallopian tube, and primary peritoneal cancer, using carboplatin and
docetaxel
treatment of progressive, platinum-refractory epithelial ovarian carcinoma,
docetaxel (cont'd) injectable Gynecology GOOVDOC I
primary peritoneal
combination with gemcitabine for advanced or recurrent uterine sarcoma
docetaxel (cont'd) injectable Gynecology GOSADG I
cancer
Intravesical Therapy for Non-Muscle Invasive Bladder Cancer using
docetaxel (cont'd) injectable Genitourinary GUBGEMDOC I
Gemcitabine and Docetaxel

docetaxel (cont'd) injectable Genitourinary intravesical use for bladder cancer if BCG and mitomycin C not available GUNOS I

docetaxel (cont'd) injectable Genitourinary palliative therapy for metastatic hormone refractory prostate cancer GUPDOC I

first-line treatment of castration sensitive, metastatic prostate cancer


docetaxel (cont'd) injectable Genitourinary using docetaxel and androgen deprivation therapy with LHRH agonist or GUPDOCADT I
LHRH antagonist with or without antiandrogen, or surgical castration

treatment of recurrent or metastatic squamous cell carcinoma of the head


docetaxel (cont'd) injectable Head and Neck HNAVDOC I
and neck with docetaxel
treatment of recurrent or metastatic squamous cell carcinoma of the head
docetaxel (cont'd) injectable Head and Neck HNAVPD I
and neck with platinum and docetaxel

* denotes change
Page 24 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment of locally advanced squamous cell carcinoma of the head and
docetaxel (cont'd) injectable Head and Neck HNLADCF I
neck with docetaxel, cisplatin and infusional fluorouracil
combination with cisplatin as first line treatment of advanced non-small
docetaxel (cont'd) injectable Lung LUAVDC I
lung cancer
docetaxel (cont'd) injectable Lung second-line treatment of non-small cell lung cancer LUAVDOC I
combination with gemcitabine as second or third line therapy for soft
docetaxel (cont'd) injectable Sarcoma SAAVGEMD I
tissue sarcomas
adjuvant therapy for breast cancer using doxorubicin and
doxorubicin injectable Breast BRAJAC I
cyclophosphamide
neoadjuvant or adjuvant therapy for breast cancer using doxorubicin and
doxorubicin injectable Breast BRAJACT I
cyclophosphamide followed by paclitaxel

neoadjuvant or adjuvant therapy for breast cancer using dose dense


doxorubicin (cont'd) injectable Breast BRAJACTG I
therapy: doxorubicin and cyclophosphamide followed by paclitaxel

neoadjuvant or adjuvant therapy for breast cancer using doxorubicin and


doxorubicin injectable Breast BRAJACTT I
cyclophosphamide followed by paclitaxel and trastuzumab

neoadjuvant or adjuvant therapy for breast cancer using dose dense


doxorubicin (cont'd) injectable Breast therapy: doxorubicin and cyclophosphamide followed by paclitaxel and BRAJACTTG I
trastuzumab
neoadjuvant or adjuvant therapy for early breast cancer using doxorubicin
doxorubicin injectable Breast BRAJACTW I
and cyclophosphamide followed by weekly paclitaxel
neoadjuvant or adjuvant therapy for breast cancer using
doxorubicin (cont'd) injectable Breast BRAJDAC I
cyclophosphamide, doxorubicin and docetaxel

doxorubicin injectable Breast palliative therapy for metastatic breast cancer using weekly doxorubicin BRAVA7 I

palliative therapy for metastatic breast cancer using doxorubicin and


doxorubicin (cont'd) injectable Breast BRAVAC I
cyclophosphamide
treatment of locally advanced breast cancer using doxorubicin and
doxorubicin (cont'd) injectable Breast BRLAACD I
cyclophosphamide followed by docetaxel
treatment of locally advanced breast cancer using doxorubicin and
doxorubicin (cont'd) injectable Breast BRLAACDT I
cyclophosphamide followed by docetaxel and trastuzumab

neoadjuvant therapy for triple-negative breast cancer using carboplatin


doxorubicin (cont'd) injectable Breast BRLACTWAC I
and weekly paclitaxel followed by doxorubicin and cyclophosphamide

Neoadjuvant Therapy for Triple-Negative Breast Cancer using Dose-


doxorubicin (cont'd) injectable Breast Dense Therapy: Carboplatin and Weekly Paclitaxel Followed by BRLACTWACG I
Doxorubicin and Cyclophosphamide

neoadjuvant therapy for breast cancer using dose dense therapy:


doxorubicin (cont'd) injectable Breast BRLATACG I
paclitaxel followed by doxorubicin and cyclophosphamide

treatment of locally advanced breast cancer using doxorubicin and


doxorubicin (cont'd) injectable Breast BRLATWAC I
cyclophosphamide followed by weekly paclitaxel
doxorubicin (cont'd) injectable Gastrointestinal palliative therapy for hepatoma using doxorubicin GIA I
transarterial chemoembolization (TACE) of hepatocellular carcinoma using
doxorubicin (cont'd) injectable Gastrointestinal GIDEBTACE I
drug-eluting bead (DEB) loaded with doxorubicin

* denotes change
Page 25 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES

Note: only funded when prescribed


hepatic trans-arterial chemoembolization for primary liver cancer or liver
doxorubicin (cont'd) injectable Gastrointestinal GIEMBOL I by specialists at BC Cancer VC &
metastasis
Royal Jubilee Hospital

palliative therapy for pancreatic endocrine tumours using streptozocin and


doxorubicin (cont'd) injectable Gastrointestinal GIENDO2 I
doxorubicin

hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with


doxorubicin (cont'd) injectable Gastrointestinal GIPMHIPEC I
peritoneal mesothelioma using doxorubicin, cisplatin and paclitaxel

doxorubicin (cont'd) injectable Genitourinary palliative therapy for advanced adrenal cortical cancer using doxorubicin GUAVD I

treatment of metastatic adrenalcortical cancer with doxorubicin, etoposide, Not reimbursed for bladder
doxorubicin (cont'd) injectable Genitourinary GUEDPM I
cisplatin and mitotane instillations
therapy for transitional cell cancers of the urothelium using methotrexate,
doxorubicin (cont'd) injectable Genitourinary GUMVAC I
vinblastine, doxorubicin and cisplatin
doxorubicin (cont'd) injectable Gynecology for use in patients with advanced endometrial cancer GOENDD I
doxorubicin (cont'd) injectable Gynecology for use in patients with advanced uterine sarcoma GOSAD I
doxorubicin (cont'd) injectable Head and Neck palliative therapy for advanced thyroid cancers using doxorubicin HNOTAVD I
palliative therapy for advanced salivary gland cancers using
doxorubicin (cont'd) injectable Head and Neck HNSAVFAC I
cyclophosphamide, doxorubicin and fluorouracil
treatment of advanced salivary gland cancers with platinum, doxorubicin
doxorubicin (cont'd) injectable Head and Neck HNSAVPAC I
and cyclophospahmide
treatment of thymoma/thymic carcinoma with cyclophosphamide,
doxorubicin (cont'd) injectable Lung LUOTCAV I
doxorubicin and vincristine

doxorubicin (cont'd) injectable Lung treatment of thymoma with platinum, doxorubicin, and cyclophosphamide LUOTPAC I

treatment of extensive small cell lung cancer with cyclophosphamide,


doxorubicin (cont'd) injectable Lung LUSCCAV I
doxorubicin and vincristine
treatment of Hodgkin's disease with doxorubicin, bleomycin, vinblastine
doxorubicin (cont'd) injectable Lymphoma LYABVD I
and dacarbazine

Treatment of Previously Untreated, Stage IV Hodgkin Lymphoma with


doxorubicin (cont'd) injectable Lymphoma LYAVDBV I
Doxorubicin, Vinblastine, Dacarbazine and Brentuximab Vedotin

treatment of lymphoma with doxorubicin, cyclophosphamide, vincristine


doxorubicin (cont'd) injectable Lymphoma LYCHOP I
and prednisone
treatment of lymphoma with doxorubicin, cyclophosphamide, vincristine,
doxorubicin (cont'd) injectable Lymphoma LYCHOPR I
prednisone and rituximab
central nervous system prophylaxis with high dose methotrexate, CHOP
doxorubicin (cont'd) injectable Lymphoma LYCHOPRMTX I
and rituximab in diffuse large B-cell lymphoma
treatment of CD30-positive peripheral T-Cell Lymphoma (PTCL) with
doxorubicin (cont'd) injectable Lymphoma doxorubicin, cyclophosphamide, prednisone (CHP) and brentuximab LYCHPBV I
vedotin

treatment of burkitt’s lymphoma and leukemia with cyclophosphamide,


doxorubicin (cont'd) injectable Lymphoma LYCODOXMR I
vincristine, doxorubicin, methotrexate, leucovorin and rituximab

* denotes change
Page 26 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment of Hodgkin's Disease with cyclophosphamide, vinblastine,
doxorubicin (cont'd) injectable Lymphoma LYCVPPABO I
procarbazine and prednisone
treatment of lymphoma with dose-adjusted etoposide, doxorubicin,
doxorubicin (cont'd) injectable Lymphoma vincristine, cyclophosphamide, prednisone and rituximab with intrathecal LYEPOCHR I
methotrexate
doxorubicin (cont'd) injectable Lymphoma lymphoma palliative chemotherapy LYPALL I
therapy for advanced soft tissue sarcoma using doxorubicin, ifosfamide-
doxorubicin (cont'd) injectable Sarcoma SAAI I
mesna
3-day doxorubicin, ifosfamide and mesna for use in patients with
doxorubicin (cont'd) injectable Sarcoma SAAI3 I
advanced soft tissue sarcoma
doxorubicin for adjuvant use for patients with non-metastatic operable
doxorubicin (cont'd) injectable Sarcoma SAAJA I
large high grade soft tissue sarcoma
adjuvant treatment of patients with soft tissue sarcoma using doxorubicin
doxorubicin (cont'd) injectable Sarcoma SAAJADIC I
and dacarbazine

doxorubicin (cont'd) injectable Sarcoma adjuvant therapy for osteosarcoma using doxorubicin and cisplatin SAAJAP I

SAIME alternating with SAVAC or SAVACM with filgrastim support at


TWO weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
doxorubicin (cont'd) injectable Sarcoma SAALT2W I
Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma
SAIME alternating with SAVAC or SAVACM with filgrastim support at
THREE weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
doxorubicin (cont'd) tablet, injectable Sarcoma SAALT3W I
Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma
doxorubicin (cont'd) injectable Sarcoma therapy for advanced soft tissue sarcoma using doxorubicin SAAVA I
treatment of patients with soft tissue sarcoma using doxorubicin and
doxorubicin (cont'd) injectable Sarcoma SAAVADIC I
dacarbazine

doxorubicin (cont'd) injectable Sarcoma therapy of advanced osteosarcoma using doxorubicin and cisplatin SAAVAP I

doxorubicin (cont'd) injectable Sarcoma treatment of sarcomas with vincristine, doxorubicin and cyclophosphamide SAVAC I

Treatment of Sarcomas with Pelvic Primaries or Chemotherapy-Induced


doxorubicin (cont'd) injectable Sarcoma SAVACM I
Hematuria using Vincristine, Doxorubicin, Cyclophosphamide and Mesna

Other tumour site


Not Otherwise Not reimbursed for bladder
doxorubicin (cont'd) injectable code followed by I
Specified instillations
‘NOS’ (e.g. BRNOS)

* denotes change
Page 27 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
doxorubicin pegylated treatment of platinum resistant epithelial ovarian cancer with bevacizumab
injectable Gynecology GOOVBEVLD I
liposomal and pegylated liposomal doxorubicin
doxorubicin pegylated first line treatment of epithelial ovarian cancer using doxorubicin pegylated
injectable Gynecology GOOVFPLDC I
liposomal liposomal and carboplatin
doxorubicin pegylated treatment of epithelial ovarian cancer relapsing after primary treatment
injectable Gynecology GOOVLDOX I
liposomal using pegylated liposomal doxorubicin
doxorubicin pegylated treatment of epithelial ovarian cancer relapsing after primary treatment
injectable Gynecology GOOVPLDC I
liposomal using pegylated liposomal doxorubicin and carboplatin
doxorubicin pegylated
injectable Kaposi's Sarcoma Kaposi’s sarcoma KSLDO I
liposomal
doxorubicin pegylated Treatment of Relapsed or Refractory Hodgkin Lymphoma with
injectable Lymphoma LYGVLD I
liposomal Gemcitabine, Vinorelbine and Doxorubicin Pegylated Liposomal
drug-eluting bead (DEB)
loaded with doxorubicin transarterial chemoembolization (TACE) of hepatocellular carcinoma using
other Gastrointestinal GIDEBTACE I
(DC Bead® or drug-eluting bead (DEB) loaded with doxorubicin
HepaSphere™)
treatment of locally advanced non-small cell lung cancer using
durvalumab injectable Lung LULADUR I
durvalumab
treatment of locally advanced non-small cell lung cancer using 4-weekly
durvalumab injectable Lung LULADUR4 I
durvalumab
First-Line Treatment of ROS1-Positive Advanced Non-Small Cell Lung
entrectinib capsule Lung ULUAVENT* R
Cancer (NSCLC) with Entrectinib
Therapy for Metastatic Castration Sensitive Prostate Cancer using
enzalutamide tablet Genitourinary UGUMCSPENZ R
Enzalutamide
Therapy for Non-Metastatic Castration Resistant Prostate Cancer Using
enzalutamide tablet Genitourinary UGUNMPENZ R
Enzalutamide
Palliative Therapy for Metastatic Castration Resistant Prostate Cancer
enzalutamide tablet Genitourinary UGUPENZ R
Using Enzalutamide
adjuvant therapy for breast cancer using fluorouracil, epirubicin and
epirubicin injectable Breast BRAJFEC I
cyclophosphamide
neoadjuvant or adjuvant therapy for breast cancer using fluorouracil,
epirubicin injectable Breast BRAJFECD I
epirubicin and cyclophosphamide and docetaxel

neoadjuvant or adjuvant therapy for breast cancer using fluorouracil,


epirubicin (cont'd) injectable Breast BRAJFECDT I
epirubicin and cyclophosphamide followed by docetaxel and trastuzumab

treatment of operable cancer of the stomach, stomach-esophagus


epirubicin (cont'd) injectable Gastrointestinal junction or lower 1/3 esophagus, given before and after surgery, using GIGECC I
epirubicin, cisplatin and capecitabine

epirubicin (cont'd) injectable Genitourinary intravesical use for bladder cancer if BCG and mitomycin C not available GUNOS I

Other tumour site


Not Otherwise
epirubicin (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. BRNOS)

eribulin injectable Breast Palliative Therapy for Metastatic Breast Cancer using Eribulin BRAVERIB I
eribulin injectable Sarcoma Palliative Therapy for Metastatic Sarcoma using Eribulin SAAVERIB I

erlotinib tablet Lung second or third line treatment of advanced non-small cell lung cancer LUAVERL I

maintenance therapy of advanced non-small cell lung cancer after first-line


erlotinib tablet Lung LUAVMTNE I
chemotherapy

* denotes change
Page 28 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
capsule/
etoposide Neuro-Oncology carboplatin and etoposide in the treatment of recurrent ependymoma CNCARV I
injectable
capsule/ palliative treatment of patients with recurrent malignant gliomas and
etoposide Neuro-Oncology CNETO I
injectable ependymoma using low dose etoposide
capsule/ therapy for recurrent malignant brain tumours using temozolomide and
etoposide Neuro-Oncology CNTMZETO I
injectable etoposide
capsule/
etoposide Gastrointestinal palliative therapy of neuroendocrine tumours using cisplatin and etoposide GIPE I
injectable
capsule/ therapy of non-dysgerminomatous ovarian germ cell cancer using
etoposide Gynecology GOBEP I
injectable bleomycin, etoposide and cisplatin
capsule/ therapy of dysgerminomatous ovarian germ cell cancer using cisplatin and
etoposide Gynecology GOEP I
injectable etoposide
capsule/ treatment of relapsed/progressing epithelial ovarian, primary peritoneal, or
etoposide Gynecology GOOVETO I
injectable fallopian tube carcinoma using etoposide
capsule/
etoposide (cont'd) Gynecology treatment of small-cell gynecologic cancer with cisplatin and etoposide GOSCPE I
injectable
capsule/ treatment of small-cell gynecologic cancer with cisplatin and etoposide
etoposide Gynecology GOSCPERT I
injectable with radiation therapy
therapy for high-risk Gestational Trophoblastic Neoplasia (GTN) using
capsule/
etoposide (cont'd) Gynecology etoposide, methotrexate, leucovorin (folinic acid), dactinomycin, GOTDEMACO I
injectable
cyclophosphamide and vincristine
capsule/ curative therapy for germ cell cancer using bleomycin, etoposide and
etoposide (cont'd) Genitourinary GUBEP I
injectable cisplatin
capsule/ treatment of metastatic adrenalcortical cancer with doxorubicin, etoposide,
etoposide (cont'd) Genitourinary GUEDPM I
injectable cisplatin and mitotane
capsule/
etoposide (cont'd) Genitourinary therapy for nonseminoma germ cell cancer using etoposide-cisplatin GUEP I
injectable
capsule/
etoposide (cont'd) Genitourinary therapy of genitourinary small cell tumours with a platin and etoposide GUSCPE I
injectable
capsule/ therapy of genitourinary small cell tumors with a platin and etoposide with
etoposide (cont'd) Genitourinary GUSCPERT I
injectable radiation
capsule/ nonseminoma consolidation/salvage protocol using etoposide, cisplatin,
etoposide Genitourinary GUVIP2 I
injectable ifosfamide, mesna
capsule/ treatment of recurrent and metastatic squamous cell cancer with platinum
etoposide (cont'd) Head and Neck HNAVPE I
injectable and etoposide
capsule/ treatment of recurrent and/or metastatic nasopharyngeal cancer with
etoposide (cont'd) Head and Neck HNNAVPE I
injectable platinum and etoposide
capsule/ treatment of locally advanced non-small cell lung cancer using cisplatin
etoposide (cont'd) Lung LULAPERT I
injectable and etoposide with radiation

capsule/ treatment of locally advanced non-small cell lung cancer using alternative
etoposide (cont'd) Lung LULAPE2RT I
injectable dosing of cisplatin and etoposide with radiation therapy

* denotes change
Page 29 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
capsule/
etoposide (cont'd) Lung treatment of thymoma with cisplatin and etoposide LUOTPE I
injectable
capsule/
etoposide (cont'd) Lung treatment of thymoma using cisplatin and etoposide with radiation therapy LUOTPERT I
injectable
capsule/ treatment of cancer of unknown primary involving the thorax with cisplatin
etoposide (cont'd) Lung LUPUPE I
injectable and etoposide
capsule/ therapy of extensive stage small cell lung cancer with cisplatin and
etoposide (cont'd) Lung LUSCPE I
injectable etoposide
capsule/ therapy of limited stage small cell lung cancer using cisplatin and
etoposide (cont'd) Lung LUSCPERT I
injectable etoposide with radiation
capsule/ palliative therapy of extensive stage small cell lung cancer with oral
etoposide (cont'd) Lung LUSCPOE I
injectable etoposide
capsule/ treatment of hemophagocytic lymphohistiocytosis with etoposide,
etoposide (cont'd) Lymphoma HLHETCSPA I
injectable dexamethasone and cycloSPORINE
treatment of lymphoma with dose-adjusted etoposide, doxorubicin,
capsule/
etoposide (cont'd) Lymphoma vincristine, cyclophosphamide, prednisone and rituximab with intrathecal LYEPOCHR I
injectable
methotrexate
capsule/ treatment of burkitt’s lymphoma and leukemia with ifosfamide, mesna,
etoposide (cont'd) Lymphoma LYIVACR I
injectable etoposide, cytarabine and rituximab
capsule/
etoposide (cont'd) Lymphoma lymphoma palliative chemotherapy LYPALL I
injectable

capsule/ treatment of relapsed or refractory advanced stage aggressive B-cell non-


etoposide (cont'd) Lymphoma LYRICE I
injectable Hodgkin’s lymphoma with ifosfamide, carboplatin, etoposide and rituximab

capsule/ treatment of natural killer or T-Cell Lymphoma using dexamethasone,


etoposide (cont'd) Lymphoma LYSMILE I
injectable methotrexate, ifosfamide, pegaspargase and etoposide

treatment of newly diagnosed nasal, extranodal natural killer (NK) or T-cell


capsule/
etoposide (cont'd) Lymphoma lymphoma, stage IE to IIE using concurrent radiation and weekly cisplatin LYVIPDRT I
injectable
followed by etoposide, ifosfamide, cisplatin and dexamethasone

SAIME alternating with SAVAC or SAVACM with filgrastim support at


capsule/ TWO weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
etoposide (cont'd) Sarcoma SAALT2W I
injectable Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma
SAIME alternating with SAVAC or SAVACM with filgrastim support at
capsule/ THREE weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
etoposide (cont'd) SAALT3W I
injectable Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma
capsule/ 3-Day etoposide & ifosfamide-mesna for patients with advanced soft
etoposide (cont'd) Sarcoma SAAVIME3 I
injectable tissue or bony sarcomas

* denotes change
Page 30 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
capsule/
etoposide (cont'd) Sarcoma etoposide, ifosfamide-mesna (SAIME) for use in sarcomas SAIME I
injectable
capsule/ treatment of recurrent or metastatic Merkel cell carcinoma with cisplatin
etoposide (cont'd) Skin & Melanoma SMMCCPE I
injectable and etoposide

Other tumour site


capsule/ Not Otherwise
etoposide (cont'd) code followed by I
injectable Specified
‘NOS’ (e.g. HNNOS)

everolimus tablet Breast therapy for advanced breast cancer using everolimus and exemestane BRAVEVEX I

treatment of advanced neuroendocrine tumours of gastrointestinal origin


everolimus tablet Gastrointestinal UGINETEV R
(non-functional) using everolimus
Note: AFINITOR® DISPERZTM
everolimus tablet Gastrointestinal palliative treatment of advanced pancreatic neuroendocrine tumours GIPNEVER I formulation not funded

everolimus tablet Genitourinary therapy for advanced renal cancer using everolimus GUEVER I
treatment of advanced neuroendocrine tumours of lung origin (non-
everolimus (cont'd) tablet Lung ULUNETEV R
functional) using everolimus
neoadjuvant or adjuvant therapy for breast cancer using exemestane in
exemestane tablet Breast BRAJEXE I
postmenopausal women

neoadjuvant or adjuvant ovarian suppression and aromatase inhibitor in


exemestane tablet Breast BRAJLHRHAI I
premenopausal women with high-risk early stage breast cancer

exemestane tablet Breast therapy for advanced breast cancer using everolimus and exemestane BRAVEVEX I

first or second line hormonal treatment for advanced breast cancer in


exemestane tablet Breast BRAVEXE I
postmenopausal women
therapy for advanced breast cancer using a LHRH agonist and an
exemestane (cont'd) tablet Breast BRAVLHRHA I
aromatase inhibitor
hormonal treatment for advanced endometrial cancer in postmenopausal
exemestane (cont'd) tablet Gynecology GOENDAI I
women

Note: NEUPOGEN® brand will


for inpatient administration only - see BC PharmaCare Special Authority
filgrastim (GRASTOFIL®) injectable FILGRASTIM only be reimbursed for pediatric
Form for indications covered
inpatient administration

fludarabine injectable/ tablet Leukemia & BMT BMTNOS I

treatment of chronic lymphocytic leukemia or prolymphocytic leukemia with


fludarabine injectable/ tablet Lymphoma LYCLLFLUDR I
fludarabine and rituximab

treatment of chronic lymphocytic leukemia (CLL) or prolymphocytic


fludarabine injectable/ tablet Lymphoma LYFCR I
leukemia with fludarabine, cyclophosphamide and rituximab

fludarabine injectable/ tablet Lymphoma chronic lymphocytic leukemia or low grade lymphoma LYFLU I

fludarabine injectable/ tablet Lymphoma treatment of relapsed indolent lymphoma with fludarabine and rituximab LYFLUDR I

fludarabine injectable/ tablet Pediatric pediatric patients with AML treated on the CCG-2961 study
I
treatment of metastatic adrenalcortical cancer with doxorubicin, etoposide,
fludrocortisone tablet Genitourinary GUEDPM I
cisplatin and mitotane
fludrocortisone (cont'd) tablet Genitourinary mineralocorticoid deficiency associated with mitotane use GUMITO I

* denotes change
Page 31 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
adjuvant therapy for high-risk breast cancer using cyclophosphamide
fluorouracil injectable Breast BRAJCMFPO I
(oral), methotrexate and fluorouracil
adjuvant therapy for breast cancer using fluorouracil, epirubicin and
fluorouracil (cont'd) injectable Breast BRAJFEC I
cyclophosphamide
neoadjuvant or adjuvant therapy for breast cancer using fluorouracil,
fluorouracil injectable Breast BRAJFECD I
epirubicin and cyclophosphamide and docetaxel

neoadjuvant or adjuvant therapy for breast cancer using fluorouracil,


fluorouracil (cont'd) injectable Breast BRAJFECDT I
epirubicin and cyclophosphamide followed by docetaxel and trastuzumab

palliative therapy for advanced breast cancer using cyclophosphamide,


fluorouracil (cont'd) injectable Breast BRAVCMF I
methotrexate and fluorouracil

adjuvant combination chemotherapy for stage III and stage IIB colon
fluorouracil (cont'd) injectable Gastrointestinal GIAJFFOX I
cancer using oxaliplatin, fluorouracil and folinic acid (leucovorin)

adjuvant therapy of colon cancer using fluorouracil injection and infusion


fluorouracil (cont'd) injectable Gastrointestinal GIAJFL I
and leucovorin infusion

palliative combination chemotherapy for metastatic colorectal cancer using


fluorouracil (cont'd) injectable Gastrointestinal GIAVFL I
fluorouracil injection and infusion and folinic acid (leucovorin) infusion

combined modality therapy for locally advanced esophageal cancer using


fluorouracil (cont'd) injectable Gastrointestinal GIEFFOXRT I
oxaliplatin, fluorouracil, leucovorin, and radiation therapy

Note: only funded when prescribed


hepatic trans-arterial chemoembolization for primary liver cancer or liver
fluorouracil (cont'd) injectable Gastrointestinal GIEMBOL I by specialists at BC Cancer VC &
metastasis
Royal Jubilee Hospital

palliative therapy for pancreatic endocrine tumours using streptozocin and


fluorouracil (cont'd) injectable Gastrointestinal GIENDO2 I
doxorubicin

palliative combination chemotherapy for metastatic colorectal cancer using


fluorouracil (cont'd) injectable Gastrointestinal GIFFIRB I
irinotecan, fluorouracil, folinic acid (leucovorin) and bevacizumab

palliative combination chemotherapy for metastatic colorectal cancer using


fluorouracil (cont'd) injectable Gastrointestinal GIFFIRPAN I
irinotecan, fluorouracil, leucovorin, and panitumumab

palliative combination chemotherapy for metastatic colorectal cancer using


fluorouracil (cont'd) injectable Gastrointestinal GIFFOXB I
oxaliplatin, fluorouracil, leucovorin, and bevacizumab

palliative combination chemotherapy for metastatic colorectal cancer using


fluorouracil (cont'd) injectable Gastrointestinal GIFFOXPAN I
oxaliplatin, fluorouracil, leucovorin, and panitumumab

palliative combination chemotherapy for advanced pancreatic


fluorouracil (cont'd) injectable Gastrointestinal adenocarcinoma using irinotecan, oxaliplatin, fluorouracil and folinic acid GIFIRINOX I
(leucovorin)
palliative combination chemotherapy for metastatic colorectal cancer using
fluorouracil (cont'd) injectable Gastrointestinal GIFOLFIRI I
irinotecan, fluorouracil and folinic acid (leucovorin)
palliative combination chemotherapy for metastatic colorectal cancer using
fluorouracil (cont'd) injectable Gastrointestinal GIFOLFOX I
oxaliplatin, fluorouracil and folinic acid (leucovorin)

* denotes change
Page 32 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
combined modality curative therapy for carcinoma of the anal canal using
fluorouracil (cont'd) injectable Gastrointestinal GIFUART I
mitomycin, fluorouracil and radiation therapy

palliative chemotherapy for upper gastrointestinal tract cancer (gastric,


fluorouracil (cont'd) injectable Gastrointestinal esophageal, gall bladder carcinoma and cholangiocarcinoma) and GIFUC I
metastatic anal cancer using infusional fluorouracil and cisplatin

combined modality curative therapy for carcinoma of the anal canal using
fluorouracil (cont'd) injectable Gastrointestinal GIFUPART I
cisplatin, infusional fluorouracil and radiation therapy
adjuvant chemotherapy in gastric cancer patients with D2 resection (node
fluorouracil (cont'd) injectable Gastrointestinal negative) or ineligible for adjuvant chemoradiation using oxaliplatin, GIGAJFFOX I
fluorouracil, and leucovorin
palliative treatment of metastatic or inoperable, locally advanced gastric or
fluorouracil (cont'd) injectable Gastrointestinal gastroesophageal junction adenocarcinoma using cisplatin, infusional GIGAVCFT I
fluorouracil and trastuzumab
Palliative Treatment of Metastatic or Locally Advanced Gastric,
fluorouracil (cont'd) injectable Gastrointestinal Gastroesophageal Junction or Esophageal Carcinoma using Oxaliplatin, GIGAVFFOX I
Fluorouracil and Leucovorin
palliative treatment of metastatic or locally advanced HER-2 positive
fluorouracil (cont'd) injectable Gastrointestinal gastric, gastroesophageal junction, or esophageal adenocarcinoma using GIGAVFFOXT I
oxaliplatin, fluorouracil, leucovorin, and trastuzumab
perioperative treatment of resectable adenocarcinoma of the stomach,
fluorouracil (cont'd) injectable Gastrointestinal gastroesophageal junction or lower 1/3 esophagus using docetaxel, GIGFLODOC I
oxaliplatin, infusional fluorouracil, and leucovorin

palliative combination chemotherapy for metastatic gastric or esophageal


fluorouracil (cont'd) injectable Gastrointestinal GIGFOLFIRI I
adenocarcinoma using irinotecan, fluorouracil and folinic acid (leucovorin)

hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with


fluorouracil (cont'd) injectable Gastrointestinal peritoneal carcinomatosis from limited advanced colorectal and GIHIPEC I
appendiceal carcinomas using oxaliplatin and fluorouracil
adjuvant chemotherapy for resected pancreatic adenocarcinoma using
fluorouracil (cont'd) injectable Gastrointestinal GIPAJFIROX I
irinotecan, oxaliplatin, fluorouracil and leucovorin
Second-Line Treatment for Metastatic Pancreatic Cancer using
fluorouracil (cont'd) injectable Gastrointestinal GIPAVFFIRI I
Irinotecan, Fluorouracil and Leucovorin
Palliative Combination Chemotherapy for Metastatic Pancreatic Cancer
fluorouracil (cont'd) injectable Gastrointestinal GIPAVFFOX I
using Oxaliplatin, Fluorouracil and Leucovorin
Adjuvant or Neoadjuvant Combination Chemotherapy for Stage III Rectal
fluorouracil (cont'd) injectable Gastrointestinal GIRAJFFOX I
Cancer using Oxaliplatin, Fluorouracil and Leucovorin
combined modality adjuvant therapy for high risk rectal carcinoma using
fluorouracil (cont'd) injectable Gastrointestinal GIRINFRT I
capecitabine, infusional fluorouracil and radiation therapy
combined modality therapy for squamous cell cancer of the genitourinary
fluorouracil (cont'd) injectable Genitourinary GUFUPRT I
system using fluorouracil and cisplatin with radiation

* denotes change
Page 33 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
fluorouracil and leucovorin for recurrent head and neck cancer (squamous
fluorouracil (cont'd) injectable Head and Neck HNAVFUFA I
cell carcinoma)
treatment of advanced squamous cell carcinoma of the head and neck
fluorouracil (cont'd) injectable Head and Neck HNAVFUP I
cancer using fluorouracil and platinum

First-Line Treatment of Advanced Squamous Cell Carcinoma of the Head


fluorouracil (cont'd) injectable Head and Neck UHNAVPFPMB R
and Neck using Platinum, Fluorouracil and Pembrolizumab

combined chemotherapy (carboplatin and fluorouracil) and radiation


fluorouracil (cont'd) injectable Head and Neck treatment for locally advanced squamous cell carcinoma of the head and HNLACAFRT I
neck
treatment of locally advanced squamous cell carcinoma of the head and
fluorouracil (cont'd) injectable Head and Neck HNLADCF I
neck with docetaxel, cisplatin and infusional fluorouracil
fluorouracil and leucovorin for recurrent head and neck cancer
fluorouracil (cont'd) injectable Head and Neck HNNAVFUFA I
(nasopharyngeal)
treatment for advanced nasopharyngeal cancer of the head and neck
fluorouracil (cont'd) injectable Head and Neck HNNAVFUP I
using platinum and fluorouracil
palliative therapy for advanced salivary gland cancers using
fluorouracil (cont'd) injectable Head and Neck HNSAVFAC I
cyclophosphamide, doxorubicin and fluorouracil
treatment of advanced head and neck cancer using cisplatin and
fluorouracil (cont'd) injectable Head and Neck HNSAVFUP I
fluorouracil

Other tumour site


Not Otherwise
fluorouracil (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. HNNOS)

fluorouracil eyedrops Ocular Topical Therapy for Ocular Malignancies using Fluorouracil Eye Drops OCFU I

fluorouracil topical cream Skin & Melanoma skin cancer SMNOS I


Not reimbursed for vasomotor
flutamide tablet Genitourinary nonsteroidal treatment of prostate cancer GUPNSAA I
symptoms (hot flashes)
Therapy of Advanced Breast Cancer using Palbociclib and Fulvestrant
fulvestrant injectable Breast BRAVPBFLV I
with or without LHRH Agonist
Therapy of Advanced Breast Cancer using Ribociclib and Fulvestrant with
fulvestrant injectable Breast BRAVRBFLV I
or without LHRH Agonist
first-line treatment of epidermal growth factor receptor mutation-positive
gefitinib tablet Lung LUAVGEFF I
advanced NSCLC
gemcitabine injectable Breast palliative therapy for metastatic breast cancer using gemcitabine BRAVGEM I
palliative therapy for metastatic breast cancer using gemcitabine and
gemcitabine injectable Breast BRAVGEMD I
docetaxel
as palliative therapy for metastatic breast cancer using cisplatin and
gemcitabine (cont'd) injectable Breast BRAVGEMP I
gemcitabine

gemcitabine injectable Breast treatment of metastatic breast cancer using gemcitabine and paclitaxel BRAVGEMT I

first-line palliative chemotherapy for advanced gallbladder cancer and


gemcitabine (cont'd) injectable Gastrointestinal GIAVPG I
cholangiocarcinoma using gemcitabine and cisplatin
adjuvant chemotherapy for resected pancreatic adenocarcinoma using
gemcitabine (cont'd) injectable Gastrointestinal GIPAJGCAP I
capecitabine and gemcitabine

gemcitabine (cont'd) injectable Gastrointestinal adjuvant chemotherapy for pancreatic adenocarcinoma using gemcitabine GIPAJGEM I

palliative chemotherapy for pancreatic adenocarcinoma, gallbladder


gemcitabine injectable Gastrointestinal GIPGEM I
cancer, and cholangiocarcinoma using gemcitabine

* denotes change
Page 34 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
first line treatment of locally advanced and metastatic pancreatic cancer
gemcitabine (cont'd) injectable Gastrointestinal GIPGEMABR I
with paclitaxel NAB (ABRAXANE) and gemcitabine
treatment of platinum resistant epithelial ovarian cancer with bevacizumab
gemcitabine (cont'd) injectable Gynecology GOOVBEVG I
and gemcitabine
carboplatin and gemcitabine for the treatment of recurrent platinum-
gemcitabine injectable Gynecology GOOVCAG I
sensitive ovarian cancer
palliative chemotherapy for re-treatment of ovarian, tubal, and peritoneal
gemcitabine injectable Gynecology GOOVGEM I
cancer using gemcitabine
combination with docetaxel for advanced or recurrent uterine sarcoma
gemcitabine (cont'd) injectable Gynecology GOSADG I
cancer

gemcitabine (cont'd) injectable Genitourinary adjuvant therapy for urothelial carcinoma using cisplatin and gemcitabine GUAJPG I

combination with cisplatin for advanced transitional cell carcinoma of the


gemcitabine (cont'd) injectable Genitourinary GUAVPG I
bladder
intravesical therapy for non-muscle invasive bladder cancer using
gemcitabine (cont'd) injectable Genitourinary GUBGEM I
gemcitabine
Intravesical Therapy for Non-Muscle Invasive Bladder Cancer using
gemcitabine (cont'd) injectable Genitourinary GUBGEMDOC I
Gemcitabine and Docetaxel

gemcitabine (cont'd) injectable Genitourinary combination with cisplatin as neoadjuvant therapy for urothelial carcinoma GUNAJPG I

gemcitabine (cont'd) injectable Genitourinary palliative therapy for germ cell cancers using paclitaxel and gemcitabine GUTAXGEM I

treatment of loco-regionally recurrent and/or metastatic nasopharyngeal


gemcitabine (cont'd) injectable Head and Neck HNNAVGEM I
cancer with gemcitabine
treatment of local-regionally recurrent and/or metastatic nasopharyngeal
gemcitabine (cont'd) injectable Head and Neck HNNAVPG I
cancer with platinum and gemcitabine
as induction treatment of locally advanced nasopharyngeal cancer with
gemcitabine (cont'd) injectable Head and Neck HNNLAPG I
cisplatin and gemcitabine
combination with cisplatin or carboplatin as treatment of advanced non-
gemcitabine (cont'd) injectable Lung LUAVPG I
small cell lung cancer
first-line treatment of advanced squamous non-small cell lung cancer with
gemcitabine (cont'd) injectable Lung LUAVPGPMB I
platinum, gemcitabine and pembrolizumab

gemcitabine (cont'd) injectable Lung treatment of malignant mesothelioma with platinum and gemcitabine LUMMPG I

gemcitabine (cont'd) injectable Lymphoma treatment of lymphoma with gemcitabine, dexamethasone and platinum LYGDP I

treatment of lymphoma with gemcitabine, dexamethasone and platinum


gemcitabine (cont'd) injectable Lymphoma LYGDPR I
with rituximab

Treatment of Newly Diagnosed or Relapsed/Refractory Natural Killer or T-


gemcitabine (cont'd) injectable Lymphoma LYGEMOXPEG* I
Cell Lymphoma using Gemcitabine, Oxaliplatin and Pegaspargase

Treatment of Relapsed or Refractory Hodgkin Lymphoma with


gemcitabine (cont'd) injectable Lymphoma LYGVLD I
Gemcitabine, Vinorelbine and Doxorubicin Pegylated Liposomal
gemcitabine (cont'd) injectable Lymphoma palliative chemotherapy of lymphomas LYPALL I

treatment of pediatric patients with relapsed Hodgkin lymphoma with a


gemcitabine (cont'd) injectable Pediatric I
combination of ifosfamide, mesna, gemcitabine and vinorelbine (IGEV)

combination with docetaxel as second or third line therapy for soft tissue
gemcitabine (cont'd) injectable Sarcoma SAAVGEMD I
sarcomas
Treatment of Acute Myeloid Leukemia using Gemtuzumab Ozogamicin
gemtuzumab ozogamicin injectable Leukemia & BMT LKGEMOZ I
with Induction and Consolidation Chemotherapy
Therapy of Relapsed or Refractory FLT3+ Acute Myeloid Leukemia using
gilteritinib tablet Leukemia & BMT ULKAMLGIL R
Gilteritinib

* denotes change
Page 35 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES

long acting neoadjuvant or adjuvant ovarian suppression and aromatase inhibitor in


goserelin Breast BRAJLHRHAI I
injectable premenopausal women with high-risk early stage breast cancer

long acting neoadjuvant or adjuvant therapy for breast cancer using a LHRH agonist
goserelin Breast BRAJLHRHT I
injectable and tamoxifen
long acting therapy for advanced breast cancer using a LHRH agonist and an
goserelin (cont'd) Breast BRAVLHRHA I
injectable aromatase inhibitor
long acting combination therapy with tamoxifen palliative therapy for metastatic breast
goserelin (cont'd) Breast BRAVLHRHT I
injectable cancer
long acting therapy of advanced breast cancer using palbociclib and aromatase Not reimbursed for endometriosis
goserelin (cont'd) Breast BRAVPALAI I
injectable inhibitor with or without LHRH agonist
long acting Therapy of Advanced Breast Cancer using Palbociclib and Fulvestrant
goserelin (cont'd) Breast BRAVPBFLV I
injectable with or without LHRH Agonist
long acting Therapy of Advanced Breast Cancer using Ribociclib and Fulvestrant with
goserelin (cont'd) Breast BRAVRBFLV I
injectable or without LHRH Agonist
long acting therapy of advanced breast cancer using ribociclib and aromatase
goserelin (cont'd) Breast BRAVRIBAI I
injectable inhibitor with or without LHRH agonist
long acting
goserelin (cont'd) Genitourinary therapy for prostate cancer using LHRH agonist GUPLHRH I
injectable
treatment of hemophagocytic lymphohistiocytosis with etoposide,
hydrocortisone tablet, injectable Lymphoma HLHETCSPA I
dexamethasone and cycloSPORINE

Other tumour site Not reimbursed for supportive care


Not Otherwise
hydrocortisone (cont'd) tablet, injectable code followed by I
Specified
‘NOS’ (e.g. LYNOS)

Myeloid neoplasms, including but not limited to: Acute myeloid leukemia,
Myelodysplastic syndromes (e.g. Refractory anemia), Myeloproliferative
hydroxyurea capsule Leukemia & BMT LKNOS I
disease (e.g. Chronic myeloid leukemia, Polycythemia, Essential
thrombocythemia)
Lymphoid neoplasms, including but not limited to: Lymphoproliferative
hydroxyurea capsule Lymphoma LYNOS I
disease, Myeloma
ibritumomab 90Y Palliative therapy for lymphoma using radioimmunotherapy: rituximab-
injectable Lymphoma LYRITZ I
(ZEVALIN®) priming for ibritumomab 90Y (ZEVALIN®)
treatment of previously untreated chronic lymphocytic leukemia or small
ibrutinib capsule Lymphoma ULYFIBRU R
lymphocytic lymphoma using ibrutinib
treatment of relapsed or refractory chronic lymphocytic leukemia or small
ibrutinib capsule Lymphoma LYIBRU I
lymphocytic lymphoma using ibrutinib

ibrutinib (cont'd) capsule Lymphoma treatment of relapsed/refractory mantle-cell lymphoma using ibrutinib LYMIBRU I

Tumour site code


Not Otherwise
idarubicin injectable followed by ‘NOS’ I
Specified
(e.g. BRNOS)
treatment of relapsed/refractory chronic lymphocytic leukemia or small
idelalisib tablet Lymphoma LYIDELAR I
lymphocytic lymphoma using idelalisib and rituximab

* denotes change
Page 36 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
advanced therapy for relapsed testicular germ cell cancer using paclitaxel,
ifosfamide injectable Genitourinary GUTIP I
ifosfamide and cisplatin
consolidation/ salvage treatment for germ cell cancer using vinblastine,
ifosfamide injectable Genitourinary GUVEIP I
cisplatin, ifosfamide and mesna
nonseminoma consolidation/salvage protocol using etoposide, cisplatin,
ifosfamide (cont'd) injectable Genitourinary GUVIP2 I
ifosfamide, mesna
treatment of burkitt’s lymphoma and leukemia with ifosfamide, mesna,
ifosfamide (cont'd) injectable Lymphoma LYIVACR I
etoposide, cytarabine and rituximab

treatment of relapsed or refractory advanced stage aggressive B-cell non-


ifosfamide (cont'd) injectable Lymphoma LYRICE I
Hodgkin’s lymphoma with ifosfamide, carboplatin, etoposide and rituximab

treatment of natural killer or T-Cell Lymphoma using dexamethasone,


ifosfamide (cont'd) injectable Lymphoma LYSMILE I
methotrexate, ifosfamide, pegaspargase and etoposide

treatment of newly diagnosed nasal, extranodal natural killer (NK) or T-cell


ifosfamide (cont'd) injectable Lymphoma lymphoma, stage IE to IIE using concurrent radiation and weekly cisplatin LYVIPDRT I
followed by etoposide, ifosfamide, cisplatin and dexamethasone

treatment of pediatric patients with relapsed Hodgkin lymphoma with a


ifosfamide injectable Pediatric I
combination of ifosfamide, mesna, gemcitabine and vinorelbine (IGEV)

therapy for advanced soft tissue sarcoma using doxorubicin, ifosfamide-


ifosfamide injectable Sarcoma SAAI I
mesna
3-day doxorubicin, ifosfamide and mesna for use in patients with
ifosfamide (cont'd) injectable Sarcoma SAAI3 I
advanced soft tissue sarcoma
SAIME alternating with SAVAC or SAVACM with filgrastim support at
TWO weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
ifosfamide (cont'd) injectable Sarcoma SAALT2W I
Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma
SAIME alternating with SAVAC or SAVACM with filgrastim support at
THREE weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
ifosfamide (cont'd) injectable Sarcoma SAALT3W I
Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma
ifosfamide injectable Sarcoma therapy for advanced soft tissue sarcoma using ifosfamide SAAVI I
ifosfamide injectable Sarcoma 3-day ifosfamide for use in patients with advanced soft tissue sarcoma SAAVI3 I
3-Day etoposide & ifosfamide-mesna for patients with advanced soft
ifosfamide injectable Sarcoma SAAVIME3 I
tissue or bony sarcomas
ifosfamide injectable Sarcoma etoposide, ifosfamide-mesna (SAIME) for use in sarcomas SAIME I

Other tumour site


Not Otherwise
ifosfamide (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. LYNOS)

* denotes change
Page 37 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
therapy for chronic myeloid leukemia and Ph+ acute lymphoblastic
imatinib capsule/tablet Leukemia & BMT LKCMLI I
leukemia
pediatric patients with Philadelphia chromosome positive acute
imatinib capsule/tablet Pediatric I
lymphoblastic leukemia
adjuvant therapy of C-Kit positive high risk gastrointestinal stromal cell
imatinib capsule/tablet Sarcoma SAAJGI I
tumours
advanced c-kit positive and c-kit negative gastrointestinal stromal cell
imatinib (cont'd) capsule/tablet Sarcoma SAAVGI I
tumours
advanced c-kit positive gastrointestinal stromal cell tumors using 800 mg
imatinib capsule/tablet Sarcoma SAAVGIDD I
dosing of imatinib
imatinib capsule/tablet Skin & Melanoma treatment of advanced c-kit melanoma using imatinib SMAVI I
topical immunotherapy for in-transit melanoma metastases, cutaneous
imiquimod topical cream Skin & Melanoma SMIMI I
lymphoma, basal cell carcinoma using imiquimod
treatment of relapsed or refractory pre-B-cell acute lymphoblastic leukemia
inotuzumab ozogamicin injectable Leukemia & BMT ULKINOZ R
with inotuzumab ozogamicin
treatment of metastatic or advanced renal cell carcinoma using ipilimumab
ipilimumab injectable Genitourinary GUAVIPNI I
and nivolumab
first-line treatment of unresectable or metastatic melanoma using
injectable Skin & Melanoma SMAVFIPI I
ipilimumab
treatment of advanced and metastatic melanoma after prior systemic
ipilimumab injectable Skin & Melanoma SMAVIPI I
therapy
treatment of unresectable or metastatic melanoma using ipilimumab and
ipilimumab injectable Skin & Melanoma SMAVIPNI I
nivolumab
palliative third line treatment of metastatic colorectal cancer with wild-type
irinotecan injectable Gastrointestinal GIAVCETIR I
KRAS using cetuximab and irinotecan
Palliative Therapy of Metastatic Colorectal Cancer using Irinotecan and
irinotecan (cont'd) injectable Gastrointestinal GIAVRALIR I
Raltitrexed in Patients Intolerant to Fluorouracil or Capecitabine

palliative combination chemotherapy for metastatic colorectal cancer using


irinotecan (cont'd) injectable Gastrointestinal GICAPIRI I
irinotecan and capecitabine in patients unsuitable for GIFOLFIRI

palliative combination chemotherapy for metastatic colorectal cancer using


irinotecan injectable Gastrointestinal GICIRB I
irinotecan, bevacizumab and capecitabine

palliative combination chemotherapy for metastatic colorectal cancer using


irinotecan injectable Gastrointestinal GIFFIRB I
irinotecan, fluorouracil, folinic acid (leucovorin) and bevacizumab

palliative combination chemotherapy for metastatic colorectal cancer using


irinotecan injectable Gastrointestinal GIFFIRPAN I
irinotecan, fluorouracil, leucovorin, and panitumumab

* denotes change
Page 38 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
palliative combination chemotherapy for advanced pancreatic
irinotecan (cont'd) injectable Gastrointestinal adenocarcinoma using irinotecan, oxaliplatin, fluorouracil and folinic acid GIFIRINOX I
(leucovorin)
palliative combination chemotherapy for metastatic colorectal cancer using
irinotecan (cont'd) injectable Gastrointestinal GIFOLFIRI I
irinotecan, fluorouracil and folinic acid (leucovorin)
second line palliative combination chemotherapy for metastatic gastric or
irinotecan (cont'd) injectable Gastrointestinal esophageal adenocarcinoma using irinotecan, fluorouracil and folinic acid GIGFOLFIRI I
(leucovorin)

irinotecan (cont'd) injectable Gastrointestinal palliative chemotherapy of metastatic colorectal cancer using irinotecan GIIR I

palliative therapy of metastatic colorectal cancer in patients who may not


irinotecan injectable Gastrointestinal GIIRINALT I
tolerate the 3-weekly irinotecan schedule of GIIR
adjuvant chemotherapy for resected pancreatic adenocarcinoma using
irinotecan injectable Gastrointestinal GIPAJFIROX I
irinotecan, oxaliplatin, fluorouracil and leucovorin
Second-Line Treatment for Metastatic Pancreatic Cancer using
irinotecan injectable Gastrointestinal GIPAVFFIRI I
Irinotecan, Fluorouracil and Leucovorin
second line treatment of extensive stage small cell lung cancer (SCLC)
irinotecan injectable Lung LUSCPI I
with irinotecan with or without platinum
pediatric patients treated on the COG protocol ARST0531 for intermediate-
irinotecan (cont'd) injectable Pediatric I
risk rhabdomyosarcoma
pediatric patients with recurrent pediatric neuroblastoma treated on the
irinotecan (cont'd) injectable Pediatric I
COG protocol ANBL0421
pediatric patients with high risk renal tumors treated on the COG protocol
irinotecan (cont'd) injectable Pediatric I
AREN0321
pediatric patients with high risk rhabdomyosarcoma treated on the COG
irinotecan (cont'd) injectable Pediatric I
protocol ARSTO431
pediatric patients with rhabdomyosarcoma treated on the COG
irinotecan (cont'd) injectable Pediatric I
ARST08P1 protocol
pediatric patients with recurrent/refractory medulloblastomas/CNS PNET
irinotecan (cont'd) injectable Pediatric I
of childhood treated on the COG ACNS0821 protocol

isotretinoin (ACCUTANE) capsule Pediatric pediatric patients with high risk neuroblastoma I

pediatric patients treated on the COG protocol ACNS0332 for above


isotretinoin (ACCUTANE™) capsule Pediatric I
average risk medulloblastoma/PNE

lanreotide injectable Neuro-Oncology treatment of growth hormone secreting pituitary adenoma using lanreotide CNLAN I

symptomatic management of functional carcinoid and neuroendocrine


lanreotide (cont'd) injectable Gastrointestinal UGILAN R
tumours of the GI Tract using lanreotide

lapatinib tablet Breast therapy for metastatic breast cancer using capecitabine and lapatinib BRAVLCAP I

* denotes change
Page 39 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
lenalidomide capsule Leukemia & BMT therapy of myelodysplastic syndrome using lenalidomide ULKMDSL R
Bortezomib, Lenalidomide and Dexamethasone for Previously Untreated
lenalidomide capsule Myeloma UMYBLDF R
Multiple Myeloma
therapy of multiple myeloma using carfilzomib, lenalidomide with
lenalidomide capsule Myeloma UMYCARLD R
dexamethasone

treatment of relapsed and refractory multiple myeloma with daratumumab


lenalidomide capsule Myeloma UMYDARLD R
in combination with lenalidomide and dexamethasone

treatment of previously untreated multiple myeloma and not eligible for


lenalidomide capsule Myeloma UMYLDF R
stem cell transplant using lenalidomide with low-dose dexamethasone

therapy of relapsed multiple myeloma using lenalidomide with


lenalidomide (cont'd) capsule Myeloma UMYLDREL R
dexamethasone
lenalidomide capsule Myeloma maintenance therapy of multiple myeloma using lenalidomide UMYLENMTN R
lenvatinib capsule Gastrointestinal Therapy of Advanced Hepatocellular Carcinoma using Lenvatinib GILEN I
therapy for locally recurrent or metastatic, RAI-refractory differentiated
lenvatinib capsule Head and Neck HNOTLEN I
thyroid cancer using lenvatinib
neoadjuvant or adjuvant therapy for breast cancer using letrozole in
letrozole tablet Breast BRAJLET I
postmenopausal women

neoadjuvant or adjuvant ovarian suppression and aromatase inhibitor in


letrozole (cont'd) tablet Breast BRAJLHRHAI I
premenopausal women with high-risk early stage breast cancer

first or second line hormonal treatment for advanced breast cancer in


letrozole tablet Breast BRAVLET I
postmenopausal women
therapy for advanced breast cancer using a LHRH agonist and an
letrozole (cont'd) tablet Breast BRAVLHRHA I
aromatase inhibitor
therapy of advanced breast cancer using palbociclib and aromatase
letrozole tablet Breast BRAVPALAI I
inhibitor with or without LHRH agonist
therapy of advanced breast cancer using ribociclib and aromatase
letrozole tablet Breast BRAVRIBAI I
inhibitor with or without LHRH agonist

hormonal treatment for advanced endometrial cancer in postmenopausal


letrozole (cont'd) tablet Gynecology GOENDAI I
women with contraindications to tamoxifen or intolerant of tamoxifen

hormonal treatment for advanced ovarian cancer in postmenopausal


letrozole (cont'd) tablet Gynecology GOOVAI I
women

* denotes change
Page 40 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment of meningeal disease using high-dose methotrexate with
leucovorin calcium tablet, injectable Breast BRAVHDMTX I
leucovorin rescue

adjuvant combination chemotherapy for Stage III and Stage IIB colon
leucovorin calcium tablet, injectable Gastrointestinal GIAJFFOX I
cancer using oxaliplatin, fluorouracil and folinic acid (Leucovorin)

adjuvant therapy of colon cancer using fluorouracil injection and infusion


leucovorin calcium tablet, injectable Gastrointestinal GIAJFL I
and leucovorin infusion

palliative combination chemotherapy for metastatic colorectal cancer using


leucovorin calcium (cont'd) tablet, injectable Gastrointestinal GIAVFL I
fluorouracil injection and infusion and folinic acid (leucovorin) infusion

combined modality therapy for locally advanced esophageal cancer using


leucovorin calcium (cont'd) tablet, injectable Gastrointestinal GIEFFOXRT I
oxaliplatin, fluorouracil, leucovorin, and radiation therapy

palliative combination chemotherapy for metastatic colorectal cancer using


leucovorin calcium (cont'd) tablet, injectable Gastrointestinal GIFFIRB I
irinotecan, fluorouracil, folinic acid (leucovorin) and bevacizumab

palliative combination chemotherapy for metastatic colorectal cancer using


leucovorin calcium (cont'd) injectable Gastrointestinal GIFFIRPAN I
irinotecan, fluorouracil, leucovorin, and panitumumab

palliative combination chemotherapy for metastatic colorectal cancer using


leucovorin calcium (cont'd) tablet, injectable Gastrointestinal GIFFOXB I
oxaliplatin, fluorouracil, leucovorin, and bevacizumab

palliative combination chemotherapy for metastatic colorectal cancer using


leucovorin calcium (cont'd) tablet, injectable Gastrointestinal GIFFOXPAN I
oxaliplatin, fluorouracil, leucovorin, and panitumumab

palliative combination chemotherapy for advanced pancreatic


leucovorin calcium (cont'd) tablet, injectable Gastrointestinal adenocarcinoma using irinotecan, oxaliplatin, fluorouracil and folinic acid GIFIRINOX I
(leucovorin)
palliative combination chemotherapy for metastatic colorectal cancer using
leucovorin calcium tablet, injectable Gastrointestinal GIFOLFIRI I
irinotecan, fluorouracil and folinic acid (leucovorin)
palliative combination chemotherapy for metastatic colorectal cancer using
leucovorin calcium (cont'd) tablet, injectable Gastrointestinal GIFOLFOX I
oxaliplatin, fluorouracil and folinic acid (leucovorin)
adjuvant chemotherapy in gastric cancer patients with D2 resection (node
leucovorin calcium (cont'd) tablet, injectable Gastrointestinal negative) or ineligible for adjuvant chemoradiation using oxaliplatin, GIGAJFFOX I
fluorouracil, and leucovorin
Palliative Treatment of Metastatic or Locally Advanced Gastric,
leucovorin calcium (cont'd) tablet, injectable Gastrointestinal Gastroesophageal Junction or Esophageal Carcinoma using Oxaliplatin, GIGAVFFOX I
Fluorouracil and Leucovorin
palliative treatment of metastatic or locally advanced HER-2 positive
leucovorin calcium (cont'd) tablet, injectable Gastrointestinal gastric, gastroesophageal junction, or esophageal adenocarcinoma using GIGAVFFOXT I
oxaliplatin, fluorouracil, leucovorin, and trastuzumab
perioperative treatment of resectable adenocarcinoma of the stomach,
leucovorin calcium (cont'd) tablet, injectable Gastrointestinal gastroesophageal junction or lower 1/3 esophagus using docetaxel, GIGFLODOC I
oxaliplatin, infusional fluorouracil, and leucovorin

palliative combination chemotherapy for metastatic gastric or esophageal


leucovorin calcium (cont'd) tablet, injectable Gastrointestinal GIGFOLFIRI I
adenocarcinoma using irinotecan, fluorouracil and folinic acid (leucovorin)

* denotes change
Page 41 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
adjuvant chemotherapy for resected pancreatic adenocarcinoma using
leucovorin calcium (cont'd) injectable Gastrointestinal GIPAJFIROX I
irinotecan, oxaliplatin, fluorouracil and leucovorin
Second-Line Treatment for Metastatic Pancreatic Cancer using
leucovorin calcium (cont'd) injectable Gastrointestinal GIPAVFFIRI I
Irinotecan, Fluorouracil and Leucovorin
Palliative Combination Chemotherapy for Metastatic Pancreatic Cancer
leucovorin calcium (cont'd) injectable Gastrointestinal GIPAVFFOX I
using Oxaliplatin, Fluorouracil and Leucovorin
Adjuvant or Neoadjuvant Combination Chemotherapy for Stage III Rectal
leucovorin calcium (cont'd) tablet, injectable Gastrointestinal GIRAJFFOX I
Cancer using Oxaliplatin, Fluorouracil and Leucovorin
therapy for high-risk Gestational Trophoblastic Neoplasia (GTN) using
leucovorin calcium (cont'd) tablet, injectable Gynecology etoposide, methotrexate, leucovorin (folinic acid), dactinomycin, GOTDEMACO I
cyclophosphamide and vincristine

Therapy for Moderate Low-Risk Gestational Trophoblastic Cancer using GOTDMR (previously
leucovorin calcium (cont'd) tablet, injectable Gynecology I
Dactinomycin and Methotrexate GOTDLR)

fluorouracil and leucovorin for recurrent head and neck cancer (squamous
leucovorin calcium (cont'd) tablet, injectable Head and Neck HNAVFUFA I
cell carcinoma)
fluorouracil and leucovorin for recurrent head and neck cancer
leucovorin calcium (cont'd) tablet, injectable Head and Neck HNNAVFUFA I
(nasopharyngeal)

treatment of refractory or relapsing extranodal natural killer or T-Cell


leucovorin calcium (cont'd) tablet, injectable Lymphoma LYASPMEDEX I
lymphoma using pegaspargase, methotrexate and dexamethasone

central nervous system prophylaxis with high dose methotrexate, CHOP


leucovorin calcium (cont'd) tablet, injectable Lymphoma LYCHOPRMTX I
and rituximab in diffuse large B-cell lymphoma

treatment of Burkitt’s lymphoma and leukemia with cyclophosphamide,


leucovorin calcium (cont'd) tablet, injectable Lymphoma LYCODOXMR I
vincristine, doxorubicin, methotrexate, leucovorin and rituximab

Treatment of Primary and Secondary CNS Lymphoma with High-Dose


leucovorin calcium (cont'd) tablet, injectable Lymphoma LYHDMRTEM I
Methotrexate, Rituximab and Temozolomide

treatment of natural killer or T-Cell lymphoma using dexamethasone,


leucovorin calcium (cont'd) tablet, injectable Lymphoma LYSMILE I
methotrexate, ifosfamide, pegaspargase and etoposide

Other tumour site


Not Otherwise
leucovorin calcium (cont'd) tablet, injectable code followed by I
Specified
‘NOS’ (e.g. LYNOS)

* denotes change
Page 42 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
long acting neoadjuvant or adjuvant ovarian suppression and aromatase inhibitor in
leuprolide Breast BRAJLHRHAI I
injectable premenopausal women with high-risk early stage breast cancer

injectable, long neoadjuvant or adjuvant therapy for breast cancer using a LHRH agonist
leuprolide Breast BRAJLHRHT I
acting injectable and tamoxifen

injectable, long therapy for advanced breast cancer using a LHRH agonist and an
leuprolide (cont'd) Breast BRAVLHRHA I
acting injectable aromatase inhibitor

injectable, long combination therapy with tamoxifen palliative therapy for metastatic breast
leuprolide Breast BRAVLHRHT I
acting injectable cancer
Not reimbursed for endometriosis.
injectable, long therapy of advanced breast cancer using palbociclib and aromatase Leuprolide acetate IM (LUPRON®)
leuprolide (cont'd) Breast BRAVPALAI I
acting injectable inhibitor with or without LHRH agonist and SC (ELIGARD®) injectables
are both reimbursable for prostate
injectable, long Therapy of Advanced Breast Cancer using Palbociclib and Fulvestrant cancer indications (GUPLHRH).
leuprolide Breast BRAVPBFLV I
acting injectable with or without LHRH Agonist

injectable, long Therapy of Advanced Breast Cancer using Ribociclib and Fulvestrant with
leuprolide Breast BRAVRBFLV I
acting injectable or without LHRH Agonist

injectable, long therapy of advanced breast cancer using ribociclib and aromatase
leuprolide Breast BRAVRIBAI I
acting injectable inhibitor with or without LHRH agonist

injectable, long
leuprolide Genitourinary therapy for prostate cancer using LHRH agonist GUPLHRH I
acting injectable

lomustine capsule Neuro-Oncology lomustine for treatment of recurrent malignant brain tumors CNCCNU I
adjuvant lomustine, cisplatin and vincristine in adult high-risk
lomustine capsule Neuro-Oncology CNCCV I
medulloblastoma or other primitive neuroectodermal tumour
modified PCV chemotherapy of brain tumours using procarbazine,
lomustine (cont'd) capsule Neuro-Oncology CNMODPCV I
lomustine and vincristine
lomustine (cont'd) capsule Lymphoma lymphoma palliative chemotherapy LYPALL I

Other tumour site


Not Otherwise
lomustine (cont'd) capsule code followed by I
Specified
‘NOS’ (e.g. CNNOS)

Peptide Receptor Radionuclide Therapy (PRRT) using 177Lu-Dotatate


177 radio-
Lu-Dotatate Gastrointestinal (LUTATHERA) for Treatment in Patients with Somatostatin Receptor UGIPRRT R
pharmaceutical
Positive Midgut Neuroendocrine Tumours
Approval from Health Canada
mechlorethamine
topical gel Lymphoma topical mechlorethamine in cutaneous T-Cell lymphoma LYMECHLOR I Special Access Programme is
(chlormethine) (SAP)
required for each patient

Not reimbursed for appetite


medroxyprogesterone tablet Gynecology non-aromatase inhibitor hormonal treatment of endometrial cancer GOENDH I
stimulation or replacement therapy.

megestrol tablet Breast breast cancer BRAVMEG I Not reimbursed for appetite
stimulation or symptom
megestrol tablet Gynecology non-aromatase inhibitor hormonal treatment of endometrial cancer GOENDH I management

* denotes change
Page 43 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
conditioning therapy for autologous stem cell transplant using high dose
melphalan tablet, injectable Leukemia & BMT BMTMM0301 I
melphalan in the treatment of multiple myeloma

melphalan tablet, injectable Myeloma treatment of multiple myeloma using melphalan and prednisone MYMP I

treatment of multiple myeloma using melphalan, prednisone and weekly


melphalan tablet, injectable Myeloma bortezomib with the option of substituting cyclophosphamide for MYMPBOR I
melphalan

Other tumour site


Not Otherwise
melphalan tablet, injectable code followed by I
Specified
‘NOS’ (e.g. LKNOS)

Tumour site code


Not Otherwise
6-mercaptopurine tablet followed by ‘NOS’ I
Specified
(e.g. LKNOS)
therapy for relapsed testicular germ cell cancer using paclitaxel,
mesna injectable Genitourinary GUTIP I
ifosfamide and cisplatin (TIP)
consolidation/ salvage treatment for germ cell cancer using vinblastine,
mesna Genitourinary GUVEIP I
cisplatin, ifosfamide and mesna
nonseminoma consolidation/salvage protocol using etoposide, cisplatin,
mesna injectable GUVIP2 I
Genitourinary ifosfamide, mesna
Treatment of Burkitt’s lymphoma and leukemia with ifosfamide, mesna,
mesna (cont'd) injectable Lymphoma LYIVACR I
etoposide, cytarabine and rituximab
treatment of relapsed or refractory advanced stage aggressive B-Cell Non-
mesna (cont'd) injectable Hodgkin’s Lymphoma with ifosfamide, carboplatin, etoposide and LYRICE I
rituximab
treatment of Natural Killer or T-Cell Lymphoma using dexamethasone,
mesna (cont'd) injectable LYSMILE I
methotrexate, ifosfamide, pegaspargase and etoposide

treatment of newly diagnosed Nasal, Extranodal Natural Killer (NK) or T-


mesna (cont'd) injectable cell lymphoma, using concurrent radiation and weekly cisplatin followed by LYVIPDRT I Approved for use ONLY as an uro-
etoposide, ifosfamide, cisplatin and dexamethasone  protector for ifosfamide or high
dose cyclophosphamide
treatment of pediatric patients with relapsed Hodgkin lymphoma with a
mesna injectable Pediatric I
combination of ifosfamide, mesna, gemcitabine and vinorelbine (IGEV)

therapy for advanced soft tissue sarcoma using doxorubicin, ifosfamide-


mesna injectable Sarcoma SAAI I
mesna
3-day doxorubicin, ifosfamide and mesna for use in patients with
mesna (cont'd) injectable Sarcoma SAAI3 I
advanced soft tissue sarcoma
SAIME alternating with SAVAC or SAVACM with filgrastim support at
TWO weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
mesna (cont'd) injectable Sarcoma SAALT2W I
Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma
SAIME alternating with SAVAC or SAVACM with filgrastim support at
THREE weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
mesna (cont'd) injectable Sarcoma SAALT3W I
Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma

* denotes change
Page 44 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
mesna (cont'd) injectable Sarcoma therapy for advanced soft tissue sarcoma using ifosfamide SAAVI I

mesna injectable 3-day ifosfamide for use in patients with advanced soft tissue sarcoma SAAVI3 I
Sarcoma
3-day etoposide & ifosfamide-mesna for patients with advanced soft
mesna injectable SAAVIME3 I
Sarcoma tissue or bony sarcomas
mesna (cont'd) injectable Sarcoma etoposide, ifosfamide-mesna (SAIME) for use in sarcomas SAIME I
Approved for use ONLY as an uro-
Treatment of Sarcomas with Pelvic Primaries or Chemotherapy-Induced protector for ifosfamide or high
mesna (cont'd) injectable Sarcoma SAVACM I
Hematuria using Vincristine, Doxorubicin, Cyclophosphamide and Mesna dose cyclophosphamide
mesna dosage modification for hematuria secondary to
mesna (cont'd) injectable Supportive Care SCMESNA I
oxazaphosphorines

Other tumour site


Not Otherwise
mesna (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. SANOS)

adjuvant therapy for high-risk breast cancer using cyclophosphamide


methotrexate tablet, injectable Breast BRAJCMFPO I
(oral), methotrexate and fluorouracil
palliative therapy for advanced breast cancer using cyclophosphamide,
methotrexate (cont'd) tablet, injectable Breast BRAVCMF I
methotrexate and fluorouracil
treatment of meningeal disease using high-dose methotrexate with
methotrexate (cont'd) tablet, injectable Breast BRAVHDMTX I
leucovorin rescue
therapy for high-risk Gestational Trophoblastic Neoplasia (GTN) using
methotrexate tablet, injectable Gynecology etoposide, methotrexate, leucovorin (folinic acid), dactinomycin, GOTDEMACO I
cyclophosphamide and vincristine

Therapy for Moderate Low-Risk Gestational Trophoblastic Cancer using GOTDMR (previously
methotrexate (cont'd) tablet, injectable Gynecology I
Dactinomycin and Methotrexate GOTDLR)

therapy for transitional cell cancers of the urothelium using methotrexate,


methotrexate tablet, injectable Genitourinary GUMVAC I
vinblastine, doxorubicin and cisplatin
treatment of head and neck cancer using methotrexate as standard Not reimbursed for rheumatoid
methotrexate tablet, injectable Head and Neck HNAVM I
therapy arthritis, psoriasis.
methotrexate (cont'd) tablet, injectable Kaposi's Sarcoma therapy for Kaposi's Sarcoma using vinblastine-vincristine KSVB I
treatment of hemophagocytic lymphohistiocytosis with etoposide,
methotrexate (cont'd) tablet, injectable Lymphoma HLHETCSPA I
dexamethasone and cycloSPORINE

treatment of refractory or relapsing extranodal natural killer or T-Cell


methotrexate (cont'd) tablet, injectable Lymphoma LYASPMEDEX I
lymphoma using pegaspargase, methotrexate and dexamethasone

central nervous system prophylaxis with high dose methotrexate, CHOP


methotrexate (cont'd) tablet, injectable Lymphoma LYCHOPRMTX I
and rituximab in diffuse large B-cell lymphoma

treatment of burkitt’s lymphoma and leukemia with cyclophosphamide,


methotrexate (cont'd) tablet, injectable Lymphoma LYCODOXMR I
vincristine, doxorubicin, methotrexate, leucovorin and rituximab

treatment of lymphoma with dose-adjusted etoposide, doxorubicin,


methotrexate (cont'd) tablet, injectable Lymphoma vincristine, cyclophosphamide, prednisone and rituximab with intrathecal LYEPOCHR I
methotrexate

* denotes change
Page 45 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
Treatment of Primary and Secondary CNS Lymphoma with High-Dose
methotrexate (cont'd) tablet, injectable Lymphoma LYHDMRTEM I
Methotrexate, Rituximab and Temozolomide
Central Nervous System Prophylaxis with High-Dose Methotrexate in
methotrexate (cont'd) tablet, injectable Lymphoma LYHDMTXPRO I
Diffuse Large B-Cell Lymphoma

methotrexate (cont'd) tablet, injectable Lymphoma treatment of lymphoma using intrathecal methotrexate and cytarabine LYIT I

treatment of Burkitt’s Lymphoma and Leukemia with ifosfamide, mesna,


methotrexate (cont'd) tablet, injectable Lymphoma LYIVACR I
etoposide, cytarabine and rituximab

methotrexate (cont'd) tablet, injectable Lymphoma lymphoma palliative chemotherapy LYPALL I


Not reimbursed for rheumatoid
treatment of natural killer or T-Cell Lymphoma using dexamethasone, arthritis, psoriasis.
methotrexate (cont'd) tablet, injectable Lymphoma LYSMILE I
methotrexate, ifosfamide, pegaspargase and etoposide

therapy for solid tumours using intrathecal methotrexate and/or thiotepa


methotrexate (cont'd) tablet, injectable Miscellaneous Origins MOIT I
and/or cytarabine
palliative therapy for aggressive fibromatosis using weekly or alternate
methotrexate (cont'd) tablet, injectable Sarcoma SAMV I
week methotrexate and vinblastine intravenously

Other tumour site


Not Otherwise
methotrexate (cont'd) tablet, injectable code followed by I
Specified
‘NOS’ (e.g. MYNOS)

Treatment of Cutaneous T-Cell Lymphoma (Sézary Syndrome) with


methoxsalen injectable Lymphoma LYMFECP I
Extracorporeal Photopheresis
Only reimbursable when
prescribed by physicians in the
methyl aminolevulinate
topical cream Skin & Melanoma topical therapy for skin cancer with PDT (Photodynamic Therapy) SMPDT I Skin Tumour Group within the Skin
(METVIX®)
PDT Program of the BC Cancer
Agency
therapy of FLT3+ acute myeloid leukemia using midostaurin in
midostaurin capsule Leukemia & BMT LKAMLMIDO I
combination with induction and consolidation chemotherapy
combined modality therapy for carcinoma of the anal canal using
mitomycin injectable Gastrointestinal GICART I
mitomycin, capecitabine and radiation therapy
Only funded when prescribed by
hepatic trans-arterial chemoembolization for primary liver cancer or liver
mitomycin injectable Gastrointestinal GIEMBOL I specialists at BC Cancer VC &
metastasis
Royal Jubilee Hospital
combined modality curative therapy for carcinoma of the anal canal using
mitomycin (cont'd) injectable Gastrointestinal GIFUART I
mitomycin, fluorouracil and radiation therapy
chemotherapy of pseudomyxoma peritonei using intraperitoneal mitomycin
mitomycin (cont'd) injectable Gastrointestinal GIFUIP I
and fluorouracil

* denotes change
Page 46 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with
mitomycin (cont'd) injectable Gastrointestinal peritoneal carcinomatosis from limited advanced colorectal and GIHIPEC I
appendiceal carcinomas using oxaliplatin and fluorouracil
combined modality therapy for squamous cell cancer of the genitourinary
mitomycin (cont'd) injectable Genitourinary GUFUPRT I
system using fluorouracil and cisplatin with radiation
intravesical therapy for non-muscle invasive cell bladder cancer using GUBMITO
mitomycin injectable Genitourinary I
mitomycin
mitomycin eye drops Ocular eye drops as topical therapy for ocular malignancies OCMITO I

Other tumour site


Not Otherwise
mitomycin (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. GUNOS)

mitotane tablet Genitourinary treatment of advanced adrenal cortical cancer GUMITO I


treatment of metastatic adrenalcortical cancer with doxorubicin, etoposide,
mitotane tablet Genitourinary GUEDPM I
cisplatin and mitotane
palliative therapy for hormone-refractory prostate cancer using
mitoxantrone injectable Genitourinary GUPMX I
mitoxantrone and prednisone

Other tumour site


Not Otherwise
mitoxantrone injectable code followed by I
Specified
‘NOS’ (e.g. BRNOS)

nilotinib tablet Leukemia & BMT Treatment of Chronic Myeloid Leukemia using Nilotinib LKCMLN I
prostate carcinoma patients who are intolerant to bicalutamide or Not reimbursed for vasomotor
nilutamide tablet Genitourinary GUPNSAA I
flutamide, at 150 mg po daily symptoms (hot flashes)
Maintenance Treatment of Newly Diagnosed Platinum Responsive
niraparib capsule Gynecology UGOOVFNIRM R
Epithelial Ovarian Cancer using Niraparib
Maintenance Treatment of Relapsed Platinum Sensitive and Responsive
niraparib capsule Gynecology UGOOVNIRAM R
Epithelial Ovarian Cancer using Niraparib
treatment of metastatic or advanced renal cell carcinoma using ipilimumab
nivolumab injectable Genitourinary GUAVIPNI I
and nivolumab

treatment of metastatic or advanced renal cell carcinoma using nivolumab GUAVNIV I

treatment of metastatic or advanced renal cell carcinoma using 4-weekly


nivolumab (cont'd) injectable Genitourinary GUAVNIV4 I
nivolumab

Palliative Therapy for Unresectable, Platinum-Refractory, Recurrent or


nivolumab injectable Head and Neck HNAVNIV I
Metastatic Squamous Cell Cancer of the Head and Neck using Nivolumab

Palliative Therapy for Unresectable, Platinum-Refractory, Recurrent or


nivolumab injectable Head and Neck Metastatic Squamous Cell Cancer of the Head and Neck using 4-Weekly HNAVNIV4 I
Nivolumab
nivolumab injectable Lung treatment of advanced non-small cell lung cancer using nivolumab LUAVNIV I
treatment of advanced non-small cell lung cancer using 4-weekly
nivolumab injectable Lung LUAVNIV4 I
nivolumab

Lymphoma treatment of relapsed or refractory Hodgkin lymphoma using nivolumab LYNIV I

treatment of relapsed or refractory Hodgkin lymphoma using 4-weekly


Lymphoma LYNIV4 I
nivolumab
adjuvant treatment of resected stage III-IV NED melanoma using
nivolumab injectable Skin & Melanoma SMAJNIV I
nivolumab

* denotes change
Page 47 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
adjuvant treatment of resected stage III-IV NED melanoma using 4-weekly
nivolumab (cont'd) injectable Skin & Melanoma SMAJNIV4 I
nivolumab
treatment of unresectable or metastatic melanoma using ipilimumab and
nivolumab injectable Skin & Melanoma SMAVIPNI I
nivolumab

nivolumab injectable Skin & Melanoma treatment of unresectable or metastatic melanoma using nivolumab SMAVNIV I

treatment of unresectable or metastatic melanoma using 4-weekly


nivolumab injectable Skin & Melanoma SMAVNIV4 I
nivolumab
treatment of previously untreated chronic lymphocytic leukemia using
obinutuzumab injectable Lymphoma LYOBCHLOR I
obinutuzumab in combination with chlorambucil
treatment of rituximab-refractory follicular lymphoma with obinutuzumab in
obinutuzumab injectable Lymphoma LYOBBEND I
combination with bendamustine
Treatment of Previously Untreated Chronic Lymphocytic Leukemia or
obinutuzumab injectable Lymphoma LYVENOB I
Small Lymphocytic Lymphoma using Venetoclax and Obinutuzumab
short acting
octreotide Neuro-Oncology treatment of growth hormone secreting pituitary adenoma CNNOS I
injectable
management of non-functional neuroendocrine tumours of the GI tract;
octreotide injectable Gastrointestinal symptomatic management of functional carcinoid and neuroendocrine GINOS I
tumours of the GI tract
long acting
octreotide Neuro-Oncology treatment of growth hormone secreting pituitary adenoma CNOCTLAR I
injectable
long acting
octreotide Gastrointestinal management of non-functional neuroendocrine tumours of the GI tract GINFOCLAR I
injectable
long acting symptomatic management of functional carcinoid and neuroendocrine
octreotide Gastrointestinal GIOCTLAR I
injectable tumors of the GI tract
Maintenance Treatment of Newly Diagnosed BRCA-Mutated Platinum
olaparib tablet Gynecology GOOVFOLAM I
Responsive Epithelial Ovarian Cancer using Olaparib
Note: capsule formulation not
Maintenance Treatment of Relapsed, BRCA-Mutated, Platinum Sensitive funded
olaparib tablet Gynecology GOOVOLAPM I
and Responsive Epithelial Ovarian Cancer using Olaparib

treatment of EGFR T790M mutation-positive advanced non-small cell lung


osimertinib tablet Lung LUAVOSI I
cancer with osimertinib
first-line treatment of EGFR mutation-positive advanced non-small cell
osimertinib tablet Lung LUAVOSIF I
lung cancer with osimertinib
adjuvant combination chemotherapy for stage III and IIB colon cancer with
oxaliplatin injectable Gastrointestinal GIAJCAPOX I
capecitabine
adjuvant combination chemotherapy for stage III and IIB colon cancer with
oxaliplatin (cont'd) injectable Gastrointestinal GIAJFFOX I
fluorouracil and folinic acid
adjuvant combination chemotherapy for node-positive colon cancer using
oxaliplatin injectable Gastrointestinal oxaliplatin and raltitrexed in patients intolerant to fluorouracil or GIAJRALOX I
capecitabine
Palliative Therapy of Metastatic Colorectal Cancer using Oxaliplatin and
oxaliplatin injectable Gastrointestinal GIAVRALOX I
Raltitrexed in Patients Intolerant to Fluorouracil or Capecitabine
palliative combination chemotherapy for metastatic colorectal cancer using
oxaliplatin injectable Gastrointestinal GICAPOX I
oxaliplatin and capecitabine
palliative combination chemotherapy for metastatic colorectal cancer using
oxaliplatin (cont'd) injectable Gastrointestinal GICOXB I
oxaliplatin, bevacizumab and capecitabine

* denotes change
Page 48 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES

combined modality therapy for locally advanced esophageal cancer using


oxaliplatin (cont'd) injectable Gastrointestinal GIEFFOXRT I
oxaliplatin, fluorouracil, leucovorin, and radiation therapy

palliative combination chemotherapy for metastatic colorectal cancer using


oxaliplatin injectable Gastrointestinal GIFFOXB I
oxaliplatin, fluorouracil, leucovorin, and bevacizumab

palliative combination chemotherapy for metastatic colorectal cancer using


oxaliplatin injectable Gastrointestinal GIFFOXPAN I
oxaliplatin, fluorouracil, leucovorin, and panitumumab

palliative combination chemotherapy for advanced pancreatic


oxaliplatin (cont'd) injectable Gastrointestinal adenocarcinoma using irinotecan, oxaliplatin, fluorouracil and folinic acid GIFIRINOX I
(leucovorin)
palliative combination chemotherapy for metastatic colorectal cancer with
oxaliplatin (cont'd) injectable Gastrointestinal GIFOLFOX I
fluorouracil and folinic acid
adjuvant chemotherapy in gastric cancer patients with D2 resection (node
oxaliplatin (cont'd) injectable Gastrointestinal negative) or ineligible for adjuvant chemoradiation using oxaliplatin and GIGAJCOX I
capecitabine
adjuvant chemotherapy in gastric cancer patients with D2 resection (node
oxaliplatin injectable Gastrointestinal negative) or ineligible for adjuvant chemoradiation using oxaliplatin, GIGAJFFOX I
fluorouracil, and leucovorin
Palliative Treatment of Metastatic or Locally Advanced Gastric,
oxaliplatin injectable Gastrointestinal Gastroesophageal Junction or Esophageal Carcinoma using Capecitabine GIGAVCOX I
and Oxaliplatin
palliative treatment of metastatic or locally advanced gastric,
oxaliplatin injectable Gastrointestinal gastroesophageal junction, or esophageal adenocarcinoma using GIGAVCOXT I
capecitabine, oxaliplatin and trastuzumab
Palliative Treatment of Metastatic or Locally Advanced Gastric,
oxaliplatin (cont'd) injectable Gastrointestinal Gastroesophageal Junction or Esophageal Carcinoma using Oxaliplatin, GIGAVFFOX I
Fluorouracil and Leucovorin
palliative treatment of metastatic or locally advanced HER-2 positive
oxaliplatin injectable Gastrointestinal gastric, gastroesophageal junction, or esophageal adenocarcinoma using GIGAVFFOXT I
oxaliplatin, fluorouracil, leucovorin, and trastuzumab
perioperative treatment of resectable adenocarcinoma of the stomach,
oxaliplatin injectable Gastrointestinal gastroesophageal junction or lower 1/3 esophagus using docetaxel, GIGFLODOC I
oxaliplatin, infusional fluorouracil, and leucovorin
hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with
oxaliplatin (cont'd) injectable Gastrointestinal peritoneal carcinomatosis from limited advanced colorectal and GIHIPEC I
appendiceal carcinomas using oxaliplatin and fluorouracil
adjuvant chemotherapy for resected pancreatic adenocarcinoma using
oxaliplatin (cont'd) injectable Gastrointestinal GIPAJFIROX I
irinotecan, oxaliplatin, fluorouracil and leucovorin
Palliative Combination Chemotherapy for Metastatic Pancreatic Cancer
oxaliplatin (cont'd) injectable Gastrointestinal GIPAVFFOX I
using Oxaliplatin, Fluorouracil and Leucovorin
Adjuvant or Neoadjuvant Combination Chemotherapy for Stage III Rectal
oxaliplatin injectable Gastrointestinal GIRAJCOX I
Cancer using Oxaliplatin and Capecitabine
Adjuvant or Neoadjuvant Combination Chemotherapy for Stage III Rectal
oxaliplatin injectable Gastrointestinal GIRAJFFOX I
Cancer using Oxaliplatin, Fluorouracil and Leucovorin

Treatment of Newly Diagnosed or Relapsed/Refractory Natural Killer or T-


oxaliplatin (cont'd) injectable Lymphoma LYGEMOXPEG* I
Cell Lymphoma using Gemcitabine, Oxaliplatin and Pegaspargase

* denotes change
Page 49 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
neoadjuvant or adjuvant therapy for breast cancer using doxorubicin and
paclitaxel injectable Breast BRAJACT I
cyclophosphamide followed by paclitaxel

neoadjuvant or adjuvant therapy for breast cancer using dose dense


paclitaxel injectable Breast BRAJACTG I
therapy: doxorubicin and cyclophosphamide followed by paclitaxel

neoadjuvant or adjuvant therapy for breast cancer using doxorubicin and


paclitaxel (cont'd) injectable Breast BRAJACTT I
cyclophosphamide followed by paclitaxel and trastuzumab

neoadjuvant or adjuvant therapy for breast cancer using dose dense


paclitaxel (cont'd) injectable Breast therapy: doxorubicin and cyclophosphamide followed by paclitaxel and BRAJACTTG I
trastuzumab
neoadjuvant or adjuvant therapy for early breast cancer using doxorubicin
paclitaxel (cont'd) injectable Breast BRAJACTW I
and cyclophosphamide followed by weekly paclitaxel
adjuvant therapy for breast cancer using weekly paclitaxel and
paclitaxel injectable Breast BRAJTTW I
trastuzumab

paclitaxel injectable Breast treatment of metastatic breast cancer using gemcitabine and paclitaxel BRAVGEMT I

palliative therapy for metastatic breast cancer using pertuzumab,


paclitaxel (cont'd) injectable Breast trastuzumab (Herceptin®), and paclitaxel as first-line treatment for BRAVPTRAT I
advanced breast cancer
paclitaxel (cont'd) injectable Breast palliative therapy for metastatic breast cancer using paclitaxel BRAVTAX I

palliative therapy for metastatic breast cancer using weekly paclitaxel


paclitaxel injectable Breast BRAVTW I
(given weekly for 3 weeks out of 4 weeks) (replaces BRAVT7)

neoadjuvant therapy for triple-negative breast cancer using carboplatin


paclitaxel (cont'd) injectable Breast BRLACTWAC I
and weekly paclitaxel followed by doxorubicin and cyclophosphamide

Neoadjuvant Therapy for Triple-Negative Breast Cancer using Dose-


paclitaxel (cont'd) injectable Breast Dense Therapy: Carboplatin and Weekly Paclitaxel Followed by BRLACTWACG I
Doxorubicin and Cyclophosphamide

neoadjuvant therapy for breast cancer using dose dense therapy:


paclitaxel (cont'd) injectable Breast BRLATACG I
paclitaxel followed by doxorubicin and cyclophosphamide

treatment of locally advanced breast cancer using doxorubicin and


paclitaxel injectable Breast BRLATWAC I
cyclophosphamide followed by weekly paclitaxel
First-Line Palliative Treatment of Metastatic Anal Squamous Cell
paclitaxel (cont'd) injectable Gastrointestinal GIAAVCT I
Carcinoma using Carboplatin and Weekly Paclitaxel
neoadjuvant treatment of esophageal and gastroesophageal carcinomas
paclitaxel (cont'd) injectable Gastrointestinal GIENACTRT I
using carboplatin, paclitaxel and radiation therapy
second-line therapy for metastatic or locally advanced gastric or
paclitaxel (cont'd) injectable Gastrointestinal gastroesophageal junction cancer using weekly paclitaxel and GIGAVRAMT I
ramucirumab

hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with


paclitaxel (cont'd) injectable Gastrointestinal GIPMHIPEC I
peritoneal mesothelioma using doxorubicin, cisplatin and paclitaxel

* denotes change
Page 50 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
alternative treatment of gynecological malignancies using cisplatin and
paclitaxel (cont'd) injectable Gynecology GOCISP I
paclitaxel
Alternative Treatment of Gynecological Malignancies using Bevacizumab,
paclitaxel (cont'd) injectable Gynecology GOCISPBEV I
Cisplatin and Paclitaxel

combination with carboplatin as primary treatment of advanced/recurrent


paclitaxel (cont'd) injectable Gynecology GOCXCAT I
non-small cell cancer of the cervix in ambulatory care settings

paclitaxel (cont'd) injectable Gynecology primarily advanced or recurrent endometrial cancer GOENDCAT I
primary treatment of invasive epithelial ovarian, fallopian tube and primary
paclitaxel (cont'd) injectable Gynecology peritoneal cancer with high risk of relapse using bevacizumab, carboplatin GOOVCATB I
and paclitaxel

primary treatment of invasive epithelial ovarian, fallopian tube and primary


paclitaxel (cont'd) injectable Gynecology GOOVCATM I
peritoneal cancer, with no visible residual tumour (moderate-high risk)

ovarian cancer relapsing after complete remission of at least 4 months’


paclitaxel (cont'd) injectable Gynecology GOOVCATR I
duration in response to primary treatment with carboplatin and paclitaxel

primary treatment of visible residual (extreme risk) invasive epithelial


paclitaxel (cont'd) injectable Gynecology GOOVCATX I
ovarian cancer
primary treatment of metastatic/recurrent cancer of the cervix with
paclitaxel (cont'd) injectable Gynecology GOCXCATB I
bevacizumab, carboplatin and paclitaxel
treatment of platinum resistant epithelial ovarian cancer with bevacizumab
paclitaxel (cont'd) injectable Gynecology GOOVBEVP R
and paclitaxel

primary treatment of advanced epithelial ovarian, primary peritoneal, or


paclitaxel (cont'd) injectable Gynecology GOOVDDCAT I
fallopian tube carcinoma using carboplatin and weekly paclitaxel

primary treatment of stage III less than or equal to 1 cm visible residual


paclitaxel (cont'd) injectable Gynecology invasive epithelial ovarian cancer using intravenous and intraperitoneal GOOVIPPC I
paclitaxel and intraperitoneal carboplatin
progressive, platinum-refractory ovarian carcinoma, primary peritoneal
paclitaxel (cont'd) injectable Gynecology GOOVTAX3 I
carcinoma or fallopian tube carcinoma

paclitaxel (cont'd) injectable Genitourinary palliative therapy for germ cell cancers using paclitaxel and gemcitabine GUTAXGEM I

advanced therapy for relapsed testicular germ cell cancer using paclitaxel,
paclitaxel (cont'd) injectable Genitourinary GUTIP I
ifosfamide and cisplatin
treatment for unresectable, locoregionally recurrent or metastatic
paclitaxel (cont'd) injectable Head and Neck squamous cell carcinoma of the head and neck using paclitaxel and HNAVPC I
cisplatin or carboplatin

First-Line Treatment of Advanced Squamous Cell Carcinoma of the Head


paclitaxel (cont'd) injectable Head and Neck UHNAVPCPMB R
and Neck with Paclitaxel, Carboplatin and Pembrolizumab

treatment of recurrent or metastatic nasopharyngeal carcinoma with


paclitaxel (cont'd) injectable Head and Neck HNNAVPC I
carboplatin and paclitaxel

* denotes change
Page 51 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
adjuvant carboplatin and paclitaxel following resection of stage I, II and
paclitaxel (cont'd) injectable Lung LUAJPC I
IIIA non-small cell lung cancer
combination with carboplatin as first line treatment of advanced non-small
paclitaxel (cont'd) injectable Lung LUAVPC I
cell lung cancer
first-line treatment of advanced squamous non-small cell lung cancer with
paclitaxel (cont'd) injectable Lung LUAVPCPMB I
paclitaxel, carboplatin and pembrolizumab
treatment of locally advanced non-small cell lung cancer using carboplatin
paclitaxel (cont'd) injectable Lung LULACATRT I
and paclitaxel with radiation therapy
primary treatment of cancer of unknown primary origin using carboplatin
paclitaxel (cont'd) injectable Primary Unknown PUCAT I
and paclitaxel

treatment of recurrent or resistant pediatric malignant germ cell tumors


paclitaxel (cont'd) injectable Pediatric I
with paclitaxel, ifosfamide and carboplatin (COG protocol AGCT0521)

Metastatic or Unresectable Angiosarcoma using Weekly Paclitaxel (3


paclitaxel (cont'd) injectable Sarcoma SAAVTW I
Weeks out of 4 Weeks Schedule)
paclitaxel NAB Palliative Therapy for Metastatic Breast Cancer using PACLitaxel NAB
injectable Breast BRAVABR I
(ABRAXANE) (ABRAXANE)
paclitaxel NAB First Line Treatment of Locally Advanced and Metastatic Pancreatic
injectable Gastrointestinal GIPGEMABR I
(ABRAXANE) Cancer with PACLitaxel NAB (ABRAXANE) and Gemcitabine
paclitaxel NAB Alternative Treatment of Gynecological Malignancies Using CARBOplatin
injectable Gynecology GOCABR I
(ABRAXANE) and PACLitaxel NAB (ABRAXANE)
paclitaxel NAB Alternative Treatment of Gynecological Malignancies Using Bevacizumab,
injectable Gynecology GOCABRBEV I
(ABRAXANE) CARBOplatin and PACLitaxel NAB (ABRAXANE)
Therapy of Advanced Breast Cancer using Palbociclib and Aromatase
palbociclib capsule Breast BRAVPALAI I
Inhibitor with or without LHRH Agonist
Therapy of Advanced Breast Cancer using Palbociclib and Fulvestrant
palbociclib capsule Breast BRAVPBFLV I
with or without LHRH Agonist
adjuvant therapy for breast cancer in post-menopausal women using
pamidronate injectable Breast BRAJPAM I
pamidronate
bony metastases associated with breast cancer for patients who do not
pamidronate injectable Breast BRAVCLOD I
tolerate oral clodronate Not reimbursed for hypercalcemia
prevention of skeletal related events secondary to breast cancer using
pamidronate injectable Breast BRAVPAM I
pamidronate
pamidronate injectable Myeloma multiple myeloma MYPAM I
palliative third-line treatment of metastatic colorectal cancer using
panitumumab injectable Gastrointestinal GIAVPANI I
panitumumab with wild type KRAS

palliative combination chemotherapy for metastatic colorectal cancer using


panitumumab injectable Gastrointestinal GIFFIRPAN I
irinotecan, fluorouracil, leucovorin, and panitumumab

palliative combination chemotherapy for metastatic colorectal cancer using


panitumumab injectable Gastrointestinal GIFFOXPAN I
oxaliplatin, fluorouracil, leucovorin, and panitumumab

pazopanib tablet Genitourinary palliative therapy for renal cell carcinoma using pazopanib GUPAZO I

* denotes change
Page 52 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
pegaspargase treatment of refractory or relapsing extranodal natural killer or T-Cell
injectable Lymphoma LYASPMEDEX I
(ONCASPAR®) lymphoma using pegaspargase, methotrexate and dexamethasone

pegaspargase Treatment of Newly Diagnosed or Relapsed/Refractory Natural Killer or T-


injectable Lymphoma LYGEMOXPEG* I
(ONCASPAR®) Cell Lymphoma using Gemcitabine, Oxaliplatin and Pegaspargase

pegaspargase treatment of natural killer or T-Cell Lymphoma using dexamethasone,


injectable Lymphoma LYSMILE I
(ONCASPAR®) methotrexate, ifosfamide, pegaspargase and etoposide
pegaspargase treatment of acute lymphoblastic leukemia and lymphoblastic lymphoma
injectable Lymphoma LKNOS, LYNOS I
(ONCASPAR®) using pegaspargase (ONCOSPAR)
pegaspargase
injectable Pediatric pediatric patients with leukemia or lymphoma I
(ONCASPAR®) (cont'd)

peginterferon alfa-2a injectable Leukemia & BMT therapy of chronic myeloid neoplasms and hypereosinophilic syndrome LKPEGIFN I

First-Line Treatment of dMMR/MSI-H Metastatic Colorectal Cancer using


pembrolizumab injectable Gastrointestinal UGIAVPEM R
Pembrolizumab
First-Line Treatment of dMMR/MSI-H Metastatic Colorectal Cancer using
pembrolizumab injectable Gastrointestinal UGIAVPEM6 R
6-Weekly Pembrolizumab
treatment of locally advanced or metastatic urothelial carcinoma using
pembrolizumab injectable Genitourinary GUAVPEM I
pembrolizumab
treatment of locally advanced or metastatic urothelial carcinoma using 6-
pembrolizumab injectable Genitourinary GUAVPEM6 I
weekly pembrolizumab
Treatment of Metastatic Renal Cell Carcinoma Using Pembrolizumab and
pembrolizumab injectable Genitourinary GUAVPEMAX I
Axitinib
First-Line Treatment of Advanced Squamous Cell Carcinoma of the Head
pembrolizumab injectable Head and Neck UHNAVPCPMB R
and Neck with Paclitaxel, Carboplatin and Pembrolizumab
First-Line Treatment of Advanced Squamous Cell Carcinoma of the Head
pembrolizumab injectable Head and Neck UHNAVPFPMB R
and Neck using Platinum, Fluorouracil and Pembrolizumab
First-Line Treatment of Advanced Squamous Cell Carcinoma of the Head
pembrolizumab injectable Head and Neck UHNAVPMBF R
and Neck with Pembrolizumab
First-Line Treatment of Advanced Squamous Cell Carcinoma of the Head
pembrolizumab injectable Head and Neck UHNAVPMBF6 R
and Neck using 6-Weekly Pembrolizumab
Maintenance Treatment of Advanced Squamous Cell Carcinoma of the
pembrolizumab injectable Head and Neck HNAVPMBM I
Head and Neck with Pembrolizumab
Maintenance Treatment of Advanced Squamous Cell Carcinoma of the
pembrolizumab injectable Head and Neck HNAVPMBM6 I
Head and Neck using 6-Weekly Pembrolizumab
first-line treatment of advanced squamous non-small cell lung cancer with
pembrolizumab injectable Lung LUAVPCPMB I
paclitaxel, carboplatin and pembrolizumab
first-line treatment of advanced squamous non-small cell lung cancer with
pembrolizumab injectable Lung LUAVPGPMB I
platinum, gemcitabine and pembrolizumab
second-line treatment of advanced non-small cell lung cancer using
pembrolizumab injectable Lung LUAVPMB I
pembrolizumab
treatment of advanced non-small cell lung cancer using 6-weekly
pembrolizumab injectable Lung LUAVPMB6 I
pembrolizumab
first-line treatment of advanced non-small cell lung cancer using
pembrolizumab injectable Lung LUAVPMBF I
pembrolizumab
first-line treatment of advanced non-small cell lung cancer using 6-weekly
pembrolizumab injectable Lung LUAVPMBF6 I
pembrolizumab
maintenance therapy of advanced non-small cell lung cancer with
pembrolizumab injectable Lung LUAVPMBM I
pembrolizumab
maintenance therapy of advanced non-small cell lung cancer with 6-
pembrolizumab injectable Lung LUAVPMBM6 I
weekly pembrolizumab
maintenance therapy of advanced non-squamous non-small cell lung
pembrolizumab injectable Lung LUAVPPMBM I
cancer with pemetrexed and pembrolizumab
first-line treatment of advanced non-squamous non-small cell lung cancer
pembrolizumab injectable Lung LUAVPPPMB I
with platinum, pemetrexed and pembrolizumab
treatment of relapsed or refractory hodgkin lymphoma using
pembrolizumab injectable Lymphoma LYPEM I
pembrolizumab

* denotes change
Page 53 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment of relapsed or refractory hodgkin lymphoma using 6-weekly
pembrolizumab (cont'd) injectable Lymphoma LYPEM6 I
pembrolizumab
adjuvant treatment of resected stage III – IV NED melanoma using
pembrolizumab injectable Skin & Melanoma SMAJPEM I
pembrolizumab
adjuvant treatment of resected stage III – IV NED melanoma using 6-
pembrolizumab injectable Skin & Melanoma SMAJPEM6 I
weekly pembrolizumab

pembrolizumab (cont'd) injectable Skin & Melanoma treatment of unresectable or metastatic melanoma using pembrolizumab SMAVPEM I

treatment of unresectable or metastatic melanoma using 6-weekly


pembrolizumab (cont'd) injectable Skin & Melanoma SMAVPEM6 I
pembrolizumab
Adjuvant Cisplatin and Pemetrexed Following Resection of Non-Small Cell
pemetrexed injectable Lung LUAJPP I
Lung Cance
pemetrexed injectable Lung second-line treatment of advanced non-small cell lung cancer LUAVPEM I
maintenance therapy of advanced non-small cell lung cancer after first-line
pemetrexed injectable Lung LUAVPMTN I
chemotherapy
first-line treatment of advanced non-small cell lung cancer with platinum
pemetrexed injectable Lung LUAVPP I
and pemetrexed
maintenance therapy of advanced non-squamous non-small cell lung
pemetrexed injectable Lung LUAVPPMBM I
cancer with pemetrexed and pembrolizumab
first-line treatment of advanced non-squamous non-small cell lung cancer
pemetrexed injectable Lung LUAVPPPMB I
with platinum, pemetrexed and pembrolizumab

pemetrexed (cont'd) injectable Lung treatment of malignant mesothelioma with platinum and pemetrexed LUMMPP I

palliative therapy for metastatic breast cancer using pertuzumab,


pertuzumab injectable Breast trastuzumab (Herceptin®) and docetaxel as first-line treatment for BRAVPTRAD I
advanced breast cancer
palliative therapy for metastatic breast cancer using pertuzumab,
pertuzumab (cont'd) injectable Breast trastuzumab (Herceptin®), and paclitaxel as first-line treatment for BRAVPTRAT I
advanced breast cancer
plerixafor injectable hematopoietic stem cell mobilization PLERIXAFOR I
Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma and
polatuzumab vedotin injectable Lymphoma Not Eligible for Transplant using Polatuzumab Vedotin, Bendamustine and LYPOLABR* I
Rituximab

pomalidomide capsule Myeloma therapy of multiple myeloma using pomalidomide with dexamethasone UMYPOMDEX R

treatment of chronic myeloid leukemia and Ph+ acute lymphoblastic


ponatinib tablet Leukemia & BMT ULKCMLP R
leukemia using ponatinib
treatment of relapsed or refractory Peripheral T-Cell lymphoma (PTCL)
pralatrexate injectable Lymphoma ULYPRA R
with pralatrexate
prednisolone suspension Pediatric pediatric patients I
palliative therapy for metastatic castration resistant prostate cancer sing
prednisone tablet Genitourinary GUPCABA I
cabazitaxel and prednisone
Therapy for Metastatic Castration-Sensitive Prostate Cancer using
UGUMCSPABI R
Abiraterone and Prednisone
Palliative Therapy for Metastatic Castration Resistant Prostate Cancer
prednisone (cont'd) tablet Genitourinary UGUPABI R
Using Abiraterone and prednisone

prednisone tablet Genitourinary palliative therapy for metastatic hormone refractory prostate cancer GUPDOC I

palliative therapy for hormone-refractory prostate cancer using


prednisone (cont'd) tablet Genitourinary GUPMX I
mitoxantrone and prednisone
treatment of lymphoma with doxorubicin, cyclophosphamide, vincristine
prednisone tablet Lymphoma LYCHOP I
and prednisone
treatment of lymphoma with doxorubicin, cyclophosphamide, vincristine,
prednisone (cont'd) tablet Lymphoma LYCHOPR I
prednisone and rituximab

* denotes change
Page 54 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
central nervous system prophylaxis with high dose methotrexate, CHOP
prednisone (cont'd) tablet Lymphoma LYCHOPRMTX I
and rituximab in diffuse large B-cell lymphoma
treatment of CD30-positive peripheral T-Cell Lymphoma (PTCL) with
prednisone (cont'd) tablet Lymphoma doxorubicin, cyclophosphamide, prednisone (CHP) and brentuximab LYCHPBV I
vedotin
treatment of relapsed chronic lymphocytic leukemia using
prednisone tablet Lymphoma LYCLLCVPR I
cyclophosphamide, vincristine, prednisone and rituximab
advanced indolent lymphoma using cyclophosphamide, vincristine and
prednisone (cont'd) tablet Lymphoma LYCVP I
prednisone
treatment of Hodgkin's Disease with cyclophosphamide, vinblastine,
prednisone (cont'd) tablet Lymphoma LYCVPPABO I
procarbazine and prednisone
treatment of advanced indolent lymphoma using cyclophosphamide,
prednisone tablet Lymphoma LYCVPR I
vincristine, prednisone and rituximab
therapy of lymphoma, Hodgkin's disease, chronic lymphocytic leukemia or
prednisone tablet Lymphoma LYCYCLO I
multiple myeloma using cyclophosphamide
treatment of lymphoma with dose-adjusted etoposide, doxorubicin,
prednisone (cont'd) tablet Lymphoma vincristine, cyclophosphamide, prednisone and rituximab with intrathecal LYEPOCHR I
methotrexate
prednisone (cont'd) tablet Lymphoma lymphoma palliative chemotherapy LYPALL I
Bortezomib, Lenalidomide and Dexamethasone for Previously Untreated
prednisone (cont'd) tablet Myeloma UMYBLDF R
Multiple Myeloma

treatment of multiple myeloma using bortezomib, dexamethasone with or


prednisone (cont'd) tablet Myeloma MYBORPRE I
without cyclophosphamide as induction pre-stem cell transplant

treatment of relapsed multiple myeloma using bortezomib,


prednisone (cont'd) tablet Myeloma MYBORREL I
dexamethasone with or without cyclophosphamide
treatment of relapsed and refractory multiple myeloma with daratumumab
prednisone (cont'd) tablet Myeloma in combination with bortezomib and dexamethasone with or without UMYDARBD R
cyclophosphamide

treatment of relapsed and refractory multiple myeloma with daratumumab


prednisone (cont'd) tablet Myeloma UMYDARLD R
in combination with lenalidomide and dexamethasone

prednisone (cont'd) tablet Myeloma treatment of multiple myeloma using melphalan and prednisone MYMP I
treatment of multiple myeloma using melphalan, prednisone and weekly
prednisone (cont'd) tablet Myeloma bortezomib with the option of substituting cyclophosphamide for MYMPBOR I
melphalan

Other tumour site


Not Otherwise
prednisone (cont'd) tablet code followed by I
Specified
‘NOS’ (e.g. LKNOS)

* denotes change
Page 55 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
modified PCV chemotherapy of brain tumours using procarbazine,
procarbazine capsule Neuro-Oncology CNMODPCV I
lomustine and vincristine

procarbazine capsule Neuro-Oncology standard procarbazine for second-line treatment of recurrent brain tumor CNPROC I

treatment of Hodgkin's Disease with cyclophosphamide, vinblastine,


procarbazine (cont'd) capsule Lymphoma LYCVPPABO I
procarbazine and prednisone
procarbazine capsule Lymphoma lymphoma palliative chemotherapy LYPALL I

Other tumour site


Not Otherwise
procarbazine (cont'd) capsule code followed by I
Specified
‘NOS’ (e.g. CNNOS)

radio- therapy for metastatic castration resistant prostate cancer using radium-
radium-223 Genitourinary GUPRAD I
pharmaceutical 223
adjuvant combination chemotherapy for node-positive colon cancer using
raltitrexed injectable Gastrointestinal oxaliplatin and raltitrexed in patients intolerant to fluorouracil or GIAJRALOX I
capecitabine
Palliative Therapy of Metastatic Colorectal Cancer using Irinotecan and
GIAVRALIR I
Raltitrexed in Patients Intolerant to Fluorouracil or Capecitabine
Palliative Therapy of Metastatic Colorectal Cancer using Oxaliplatin and
GIAVRALOX I
Raltitrexed in Patients Intolerant to Fluorouracil or Capecitabine
unresectable or metastatic colorectal adenocarcinoma for patients with
raltitrexed injectable Gastrointestinal GIRALT I
previous fluorouracil toxicity
second-line therapy for metastatic or locally advanced gastric or
ramucirumab injectable Gastrointestinal gastroesophageal junction cancer using weekly paclitaxel and GIGAVRAMT I
ramucirumab
third line treatment of advanced gastrointestinal stromal cell tumours
regorafenib tablet Sarcoma SAAVGR I
(GIST's) using regorafenib

regorafenib tablet Gastrointestinal treatment of advanced hepatocellular carcinoma using regorafenib GIREGO I

Therapy of Advanced Breast Cancer using Ribociclib and Fulvestrant with


ribociclib tablet Breast BRAVRBFLV I
or without LHRH Agonist
Therapy of Advanced Breast Cancer using Ribociclib and Aromatase
ribociclib tablet Breast BRAVRIBAI I
Inhibitor with or without LHRH Agonist

* denotes change
Page 56 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
IV injectable pre-emptive rituximab therapy of Epstein-Barr virus related post-transplant
rituximab Leukemia & BMT BMTLPDRIT I
only lymphoproliferative disease
IV / 1400 mg SC
rituximab Lymphoma treatment of Non-Hodgkin Lymphoma with bendamustine and rituximab LYBENDR I
injectable
IV / 1400 mg SC
rituximab Lymphoma treatment of indolent B-cell lymphoma with chlorambucil and rituximab LYCHLRR I
injectable

in combination with CHOP (cyclophosphamide, doxorubicin, prednisone,


IV / 1400 mg SC
rituximab (cont'd) Lymphoma vincristine), in all stages of newly diagnosed diffuse large B-cell lymphoma LYCHOPR I
injectable
and mantle cell lymphoma, advanced stage at diagnosis
Note: Biosimilar rituximab
IV / 1400 mg SC central nervous system prophylaxis with high dose methotrexate, CHOP (RIXIMYO®, RUXIENCE®) is
rituximab Lymphoma LYCHOPRMTX I
injectable and rituximab in diffuse large B-cell lymphoma funded for intravenous rituximab
IV / 1600 mg SC treatment of relapsed/refractory chronic lymphocytic leukemia or small started on or after August 1st,
rituximab Lymphoma LYCLLBENDR I
injectable lymphocytic lymphoma with bendamustine and rituximab 2020. RITUXAN® is funded for
IV / 1600 mg SC intravenous rituximab started prior
rituximab Lymphoma treatment of chronic lymphocytic leukemia with chlorambucil and rituximab LYCLLCHLR I
injectable to and continue beyond August
IV / 1600 mg SC treatment of relapsed chronic lymphocytic leukemia using 1st, 2020.
rituximab Lymphoma LYCLLCVPR I
injectable cyclophosphamide, vincristine, prednisone and rituximab
IV / 1600 mg SC treatment of previously untreated chronic lymphocytic leukemia (CLL) with
LYCLLFBR I
injectable bendamustine and rituximab
IV / 1600 mg SC treatment of chronic lymphocytic leukemia or prolymphocytic leukemia with
rituximab (cont'd) Lymphoma LYCLLFLUDR I
injectable fludarabine and rituximab

IV / 1400 mg SC treatment of Burkitt’s lymphoma and leukemia with cyclophosphamide,


rituximab (cont'd) Lymphoma LYCODOXMR I
injectable vincristine, doxorubicin, methotrexate, leucovorin and rituximab

IV / 1400 mg SC
rituximab (cont'd) Lymphoma combination with CVP for advanced stage indolent lymphoma at diagnosis LYCVPR I
injectable

* denotes change
Page 57 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment of lymphoma with dose-adjusted etoposide, doxorubicin,
IV / 1400 mg SC
rituximab (cont'd) Lymphoma vincristine, cyclophosphamide, prednisone and rituximab with intrathecal LYEPOCHR I
injectable
methotrexate

IV / 1600 mg SC treatment of chronic lymphocytic leukemia (CLL) or prolymphocytic


rituximab (cont'd) Lymphoma LYFCR I
injectable leukemia with fludarabine, cyclophosphamide and rituximab

IV / 1400 mg SC
rituximab Lymphoma treatment of relapsed indolent lymphoma with fludarabine and rituximab LYFLUDR I
injectable
IV / 1400 mg SC treatment of lymphoma with gemcitabine, dexamethasone and platinum
rituximab (cont'd) Lymphoma LYGDPR I
injectable with rituximab
IV / 1400 mg SC Treatment of Primary and Secondary CNS Lymphoma with High-Dose
rituximab (cont'd) Lymphoma LYHDMRTEM I
injectable Methotrexate, Rituximab and Temozolomide
IV / 1600 mg SC treatment of relapsed/refractory chronic lymphocytic leukemia or small
rituximab (cont'd) Lymphoma LYIDELAR I
injectable lymphocytic lymphoma using idelalisib and rituximab
IV / 1400 mg SC treatment of Burkitt’s lymphoma and leukemia with ifosfamide, mesna, Note: Biosimilar rituximab
rituximab (cont'd) Lymphoma LYIVACR I
injectable etoposide, cytarabine and rituximab (RIXIMYO®, RUXIENCE®) is
Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma and funded for intravenous rituximab
IV / 1400 mg SC started on or after August 1st,
rituximab (cont'd) Lymphoma Not Eligible for Transplant using Polatuzumab Vedotin, Bendamustine and LYPOLABR* I
injectable 2020. RITUXAN® is funded for
Rituximab
intravenous rituximab started prior
IV / 1400 mg SC treatment of relapsed or refractory advanced stage aggressive B-cell non- to and continue beyond August
rituximab (cont'd) Lymphoma LYRICE I
injectable Hodgkin’s lymphoma with ifosfamide, carboplatin, etoposide and rituximab 1st, 2020.
follicular lymphoma progressive despite alkylating agents and purine
IV / 1400 mg SC analogues (fludarabine or cladribine), post-transplant lymphoproliferative
rituximab (cont'd) Lymphoma LYRITUX I
injectable disease, or newly diagnosed (within 6 months) asymptomatic advanced
follicular lymphoma
IV injectable palliative therapy for lymphoma using radioimmunotherapy: rituximab-
Lymphoma LYRITZ I
only priming for ibritumomab 90Y (ZEVALIN®)
IV / 1400 mg SC
rituximab (cont'd) Lymphoma maintenance treatment of indolent lymphoma LYRMTN I
injectable
IV / 1600 mg SC treatment of relapsed/refractory chronic lymphocytic leukemia or small
rituximab (cont'd) Lymphoma LYVENETOR I
injectable lymphocytic lymphoma using venetoclax and rituximab
pediatric patients treated on the COG protocols ANHL0221 for CD20
IV injectable positive post-transplant lymphoproliferative disease following solid organ
Pediatric I
only transplantation and ANHL01P1 for newly diagnosed advanced B-cell
leukemia/lymphoma
treatment of relapsed or refractory Peripheral T-Cell lymphoma (PTCL)
romidepsin injectable Lymphoma ULYROMI R
with romidepsin
ruxolitinib tablet Leukemia & BMT treatment of symptomatic myelofibrosis with ruxolitinib ULKMFRUX R
ruxolitinib tablet Leukemia & BMT treatment of polycythemia vera with ruxolitinib ULKPCVRUX R

* denotes change
Page 58 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
pediatric patients with neuroblastoma treated on the COG ANBL0032
sargramostim (SAP) injectable Pediatric I
protocol
pediatric patients with relapsed neuroblastoma treated on the COG
sargramostim injectable Pediatric I Approval from Health Canada
ANBL1021 protocol
Special Access Programme is
treatment of pediatric patients with high-risk neuroblastoma who achieve a required for each patient
sargramostim injectable Pediatric response to prior first-line multi-agent, multimodal therapy using R
dinutuximab in combination with sargramostim, aldesleukin and tretinoin

treatment of Multicentric Castleman’s Disease (MCD) negative for Human


siltuximab injectable Lymphoma Immunodeficiency Virus (HIV) and Human Herpes Virus-8 (HHV-8) Using LYSILTUX I
siltuximab
sorafenib tablet Gastrointestinal Therapy for Advanced Hepatocellular Carcinoma using Sorafenib GISORAF I

sorafenib tablet Genitourinary palliative therapy for renal cell carcinoma in patients after cytokine failure GUSORAF I

sorafenib tablet Leukemia & BMT therapy of acute myeloid leukemia using azacitidine and sorafenib LKAMLAS I
palliative therapy for pancreatic endocrine tumours using streptozocin and
streptozocin injectable Gastrointestinal GIENDO2 I
doxorubicin Approval from Health Canada
Other tumour site Special Access Programme is
Not Otherwise required for each patient
streptozocin injectable code followed by I
Specified
‘NOS’ (e.g. GINOS)

sunitinib capsule Gastrointestinal as palliative treatment of advance pancreatic neuroendocrine tumours GIPNSUNI I

palliative therapy for renal cell carcinoma in patients who are not suitable
sunitinib capsule Genitourinary GUSUNI I
candidates for interferon
second line treatment of advanced c-kit positive gastrointestinal stromal
sunitinib (cont'd) capsule Sarcoma SAAVGS I
cell tumours (GIST's) after imatinib
neoadjuvant or adjuvant therapy for breast cancer using a LHRH agonist
tamoxifen tablet Breast BRAJLHRHT I
and tamoxifen

tamoxifen tablet Breast neoadjuvant or adjuvant therapy for breast cancer using tamoxifen BRAJTAM I

tamoxifen (cont'd) tablet Breast palliative therapy for breast cancer using a LHRH agonist and tamoxifen BRAVLHRHT I

tamoxifen tablet Breast palliative therapy for breast cancer BRAVTAM I


endometrial cancernon-aromatase inhibitor hormonal treatment of
tamoxifen tablet Gynecology GOENDH I
endometrial cancer
tamoxifen tablet Gynecology therapy for advanced ovarian cancer using tamoxifen GOOVTAM I
tamoxifen (cont'd) tablet Head and Neck treatment of recurrent/metastatic salivary gland cancers HNSAVTAM I
tamoxifen tablet Sarcoma recurrent desmoid tumors/aggressive fibromatosis SATAM I

* denotes change
Page 59 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES

concomitant (dual modality) and 12 cycles of adjuvant temozolomide for


temozolomide capsule Neuro-Oncology CNAJ12TZRT I
newly diagnosed astrocytomas and oligodendrogliomas with radiation

concomitant and adjuvant temozolomide for newly diagnosed malignant


temozolomide capsule Neuro-Oncology CNAJTZRT I
gliomas with radiation
treatment of elderly newly diagnosed glioma patient with concurrent and
temozolomide capsule Neuro-Oncology CNELTZRT I
adjuvant temozolomide and radiation therapy
therapy for newly diagnosed malignant brain tumours with MGMT
temozolomide capsule Neuro-Oncology CNTEM60 I
methylation in elderly patients using temozolomide
temozolomide capsule Neuro-Oncology therapy for malignant brain tumours CNTEMOZ I
therapy for malignant brain tumours using metronomic dosing of
temozolomide (cont'd) capsule Neuro-Oncology CNTEMOZMD I
temozolomide
therapy for recurrent malignant brain tumours using temozolomide and
temozolomide (cont'd) capsule Neuro-Oncology CNTMZETO I
etoposide
palliative therapy of metastatic neuroendocrine cancer using
temozolomide (cont'd) capsule Gastrointestinal GIAVTZCAP I
temozolomide and capecitabine
Treatment of Primary and Secondary CNS Lymphoma with High-Dose
temozolomide (cont'd) capsule Lymphoma LYHDMRTEM I
Methotrexate, Rituximab and Temozolomide
temozolomide (cont'd) capsule Pediatric pediatric patients with brain tumours I
pediatric patients treated on the COG protocol ANBL0421 for recurrent
temozolomide capsule Pediatric I
neuroblastoma
pediatric patients with rhabdomyosarcoma treated on the COG
temozolomide (cont'd) capsule Pediatric I
ARST08P1 protocol
therapy for advanced solitary fibrous tumours and hemangiopericytoma
temozolomide (cont'd) capsule Sarcoma SATEMBEV I
using temozolomide and bevacizumab
temozolomide (cont'd) capsule Skin & Melanoma palliative therapy for malignant melanoma with brain metastases SMAVTMZ I
temsirolimus injectable Genitourinary therapy for advanced renal cancer using temsirolimus GUTEM I
treatment of recurrent/refractory rhabdomysarcoma in pediatric patients
temsirolimus injectable Pediatric with cyclophosphamide, vinorelbine and temsirolimus on the COG I
ARST0921 protocol
Tumour site code
Not Otherwise
teniposide injectable followed by ‘NOS’ I
Specified
(e.g. GUNOS)
Not reimbursed for symptom
testosterone enanthate injectable Breast palliative therapy for metastatic breast cancer BRAVTEST I management or appetite
stimulation
Tumour site code
Not Otherwise
thioguanine tablet followed by ‘NOS’ I
Specified
(e.g. LYNOS)

* denotes change
Page 60 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES

therapy for solid tumours using intrathecal methotrexate and/or thiotepa


thiotepa injectable Miscellaneous Origins MOIT I
and/or cytarabine

Other tumour site


Not Otherwise
thiotepa (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. GUNOS)

thyrotropin alfa injectable Head and Neck radioiodine imaging in patients with thyroid cancer and treatment HNOTTSH I
treatment of relapsed/progressive epithelial ovarian, fallopian tube or
topotecan injectable Gynecology GOOVTOP I
primary peritoneal cancer using topotecan
topotecan (cont'd) injectable Lung second line treatment of recurrent small cell lung cancer LUSCTOP I
topotecan (cont'd) injectable Pediatric pediatric sarcoma I
intermediate-risk (COG ANBL0532) and high risk (COG ANBL0531)
topotecan injectable Pediatric I
pediatric neuroblastoma
summary for treatment of recurrent/refractory neuroblastoma, ewing’s
topotecan injectable Sarcoma sarcoma, osteogenic sarcoma or rhabdomyosarcoma with SAAVTC I
topotecan/cyclophosphamide
adjuvant treatment of stage III and IV, BRAF-mutated, fully resected
trametinib tablet Skin & Melanoma SMAJDT I
melanoma using dabrafenib and trametinib
treatment of BRAF V600 mutation-positive unresectable or metastatic
trametinib tablet Skin & Melanoma SMAVDT I
melanoma using dabrafenib and trametinib
treatment of BRAF V600 mutation-positive unresectable or metastatic
trametinib tablet Skin & Melanoma SMAVTRA I
melanoma using trametinib
neoadjuvant or adjuvant therapy for breast cancer using doxorubicin and
trastuzumab injectable Breast BRAJACTT I
cyclophosphamide followed by paclitaxel and trastuzumab
neoadjuvant or adjuvant therapy for breast cancer using dose dense
trastuzumab therapy: doxorubicin and cyclophosphamide followed by paclitaxel and BRAJACTTG I
trastuzumab Note: Biosimilar trastuzumab
neoadjuvant or adjuvant therapy for breast cancer using carboplatin, (HERZUMA®, TRAZIMERA®) is
trastuzumab (cont'd) Injectable Breast BRAJDCARBT I
docetaxel and trastuzumab funded for treatment started on or
after February 1st, 2020, except
neoadjuvant or adjuvant therapy for breast cancer using fluorouracil, HERCEPTIN® continues to be
trastuzumab Injectable Breast BRAJFECDT I
epirubicin and cyclophosphamide followed by docetaxel and trastuzumab funded when trastuzumab is used
neoadjuvant or adjuvant therapy for breast cancer using trastuzumab, with pertuzumab for advanced
trastuzumab Injectable Breast BRAJTDC I breast cancer (BRAVPTRAD,
docetaxel and cyclophosphamide
BRAVPTRAT). HERCEPTIN® is
Adjuvant Therapy for Breast Cancer using Trastuzumab Following the
trastuzumab Injectable Breast BRAJTR I funded for treatment started prior
Completion of Chemotherapy (Sequential)
to February 1st, 2020.
adjuvant therapy for breast cancer using weekly paclitaxel and
trastuzumab injectable Breast BRAJTTW I
trastuzumab
palliative therapy for metastatic breast cancer using pertuzumab,
trastuzumab injectable Breast trastuzumab (Herceptin®) and docetaxel as first-line treatment for BRAVPTRAD I
advanced breast cancer

* denotes change
Page 61 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
palliative therapy for metastatic breast cancer using pertuzumab,
trastuzumab (cont'd) injectable Breast trastuzumab (Herceptin®), and paclitaxel as first-line treatment for BRAVPTRAT I
advanced breast cancer
palliative therapy for metastatic breast cancer using trastuzumab and
trastuzumab injectable Breast BRAVTCAP I
capecitabine

single agent therapy for metastatic breast cancer progressing after 1 prior
trastuzumab injectable Breast regimens (e.g., taxane) and responding to trastuzumab in combination BRAVTR I
with paclitaxel, with paclitaxel and carboplatin, or with vinorelbine

combination with 3-weekly vinorelbine as palliative therapy for metastatic Note: Biosimilar trastuzumab
trastuzumab (cont'd) Injectable Breast BRAVTRVIN I (HERZUMA®, TRAZIMERA®) is
breast cancer
funded for treatment started on or
treatment of locally advanced breast cancer using doxorubicin and
trastuzumab (cont'd) Injectable Breast BRLAACDT I after February 1st, 2020, except
cyclophosphamide followed by docetaxel and trastuzumab
HERCEPTIN® continues to be
Palliative Treatment of Metastatic or Locally Advanced Gastric, funded when trastuzumab is used
trastuzumab (cont'd) Injectable Gastrointestinal Gastroesophageal Junction or Esophageal Adenocarcinoma using GIGAVCCT I with pertuzumab for advanced
Cisplatin, Capecitabine and Trastuzumab breast cancer (BRAVPTRAD,
palliative treatment of metastatic or inoperable, locally advanced gastric or BRAVPTRAT). HERCEPTIN® is
trastuzumab (cont'd) Injectable Gastrointestinal gastroesophageal junction adenocarcinoma using cisplatin, infusional GIGAVCFT I funded for treatment started prior
fluorouracil and trastuzumab to February 1st, 2020.
palliative treatment of metastatic or locally advanced gastric,
trastuzumab (cont'd) Injectable Gastrointestinal gastroesophageal junction, or esophageal adenocarcinoma using GIGAVCOXT I
capecitabine, oxaliplatin and trastuzumab
Palliative Treatment of Metastatic or Locally Advanced Gastric,
trastuzumab (cont'd) Injectable Gastrointestinal Gastroesophageal Junction or Esophageal Carcinoma using Oxaliplatin, GIGAVFFOXT I
Fluorouracil and Leucovorin
continuation of palliative treatment of metastatic or inoperable, locally
trastuzumab (cont'd) injectable Gastrointestinal advanced gastric or gastroesophageal junction adenocarcinoma using GIGAVTR I
trastuzumab
trastuzumab emtansine adjuvant therapy for breast cancer using trastuzumab emtansine
injectable Breast UBRAJKAD R
(KADCYLA) (KADCYLA)
trastuzumab emtansine palliative therapy for metastatic breast cancer using trastuzumab
injectable Breast BRAVKAD I
(KADCYLA) emtansine (KADCYLA)
treosulfan injectable Leukemia & BMT BMTNOS I
pre-conditioning therapy with treosulfan for pediatric patients at risk for
treosulfan (SAP) injectable Pediatric busulfan-related toxicity prior to hematopoietic stem cell transplantation for R
malignant conditions
tretinoin (VESANOID®) capsule Leukemia & BMT acute promyelocytic leukemia LKNOS I
tretinoin (VESANOID®) first-line induction and consolidation therapy of acute promyelocytic
capsule Leukemia & BMT LKATOATRA I
(cont'd) leukemia using arsenic trioxide and tretinoin
first-line induction and consolidation therapy of acute promyelocytic
tretinoin (VESANOID®) capsule Leukemia & BMT LKATOP I
leukemia using arsenic trioxide, tretinoin and daunorubicin

induction and consolidation therapy of relapsed acute promyelocytic


tretinoin (VESANOID®) capsule Leukemia & BMT LKATOR I
leukemia using arsenic trioxide and tretinoin (All-Trans Retinoic Acid)

treatment of pediatric patients with high-risk neuroblastoma who achieve a


tretinoin (VESANOID®) capsule Leukemia & BMT response to prior first-line multi-agent, multimodal therapy using R
dinutuximab in combination with sargramostim, aldesleukin and tretinoin

Third- or Later-Line Therapy for Advanced Gastroesophageal Carcinoma


trifluridine-tipiracil tablet Gastrointestinal GIGAVTRFT I
using Trifluridine-Tipiracil

* denotes change
Page 62 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
treatment for locally advanced or metastatic medullary thyroid cancer
vandetanib tablet Head and Neck HNOTVAN I
using vandetanib
treatment of BRAF V600 mutation-positive unresectable or metastatic
vemurafenib tablet Skin & Melanoma SMAVVEM I
melanoma using vemurafenib
treatment of BRAF V600 mutation-positive unresectable or metastatic
vemurafenib tablet Skin & Melanoma SMAVVC I
melanoma using vemurafenib and cobimetinib
treatment of relapsed/refractory chronic lymphocytic leukemia or small
venetoclax tablet Lymphoma ULYVENETO R
lymphocytic lymphoma using venetoclax
treatment of relapsed/refractory chronic lymphocytic leukemia or small
venetoclax tablet Lymphoma LYVENETOR I
lymphocytic lymphoma using venetoclax and rituximab
Treatment of Previously Untreated Chronic Lymphocytic Leukemia or
venetoclax tablet Lymphoma LYVENOB I
Small Lymphocytic Lymphoma using Venetoclax and Obinutuzumab
therapy for transitional cell cancers of the urothelium using methotrexate,
vinblastine injectable Genitourinary GUMVAC I
vinblastine, doxorubicin and cisplatin
consolidation/ salvage treatment for germ cell cancer using vinblastine,
vinblastine injectable Genitourinary GUVEIP I
cisplatin, ifosfamide and mesna
vinblastine injectable Kaposi's Sarcoma therapy for Kaposi's Sarcoma using vinblastine-vincristine KSVB I
treatment of Hodgkin's disease with doxorubicin, bleomycin, vinblastine
vinblastine injectable Lymphoma LYABVD I
and dacarbazine

Treatment of Previously Untreated, Stage IV Hodgkin Lymphoma with


vinblastine injectable Lymphoma LYAVDBV I
Doxorubicin, Vinblastine, Dacarbazine and Brentuximab Vedotin

treatment of Hodgkin's Disease with cyclophosphamide, vinblastine,


vinblastine injectable Lymphoma LYCVPPABO I
procarbazine and prednisone
vinblastine (cont'd) injectable Lymphoma lymphoma palliative chemotherapy LYPALL I
palliative therapy for aggressive fibromatosis using weekly or alternate
vinblastine (cont'd) injectable Sarcoma SAMV I
week methotrexate and vinblastine intravenously

Other tumour site


Not Otherwise
vinblastine injectable code followed by I
Specified
‘NOS’ (e.g. LYNOS)

adjuvant lomustine, cisplatin and vincristine in adult high-risk


vincristine injectable Neuro-Oncology CNCCV I
medulloblastoma or other primitive neuroectodermal tumour
modified PCV chemotherapy of brain tumours using procarbazine,
vincristine (cont'd) injectable Neuro-Oncology CNMODPCV I
lomustine and vincristine
therapy for high-risk Gestational Trophoblastic Neoplasia (GTN) using
vincristine (cont'd) injectable Gynecology etoposide, methotrexate, leucovorin (folinic acid), dactinomycin, GOTDEMACO I
cyclophosphamide and vincristine
vincristine (cont'd) injectable Kaposi's sarcoma therapy for Kaposi's Sarcoma using vinblastine-vincristine KSVB I
treatment of thymoma/thymic carcinoma with cyclophosphamide,
vincristine (cont'd) injectable Lung LUOTCAV I
doxorubicin and vincristine
treatment of extensive small cell lung cancer with cyclophosphamide,
vincristine (cont'd) injectable Lung LUSCCAV I
doxorubicin and vincristine
treatment of lymphoma with doxorubicin, cyclophosphamide, vincristine
vincristine (cont'd) injectable Lymphoma LYCHOP I
and prednisone
treatment of lymphoma with doxorubicin, cyclophosphamide, vincristine,
vincristine (cont'd) injectable Lymphoma LYCHOPR I
prednisone and rituximab

* denotes change
Page 63 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
central nervous system prophylaxis with high dose methotrexate, CHOP
vincristine (cont'd) injectable Lymphoma LYCHOPRMTX I
and rituximab in diffuse large B-cell lymphoma
treatment of relapsed chronic lymphocytic leukemia using
vincristine (cont'd) injectable Lymphoma LYCLLCVPR I
cyclophosphamide, vincristine, prednisone and rituximab

treatment of Burkitt’s Lymphoma and Leukemia with cyclophosphamide,


vincristine (cont'd) injectable Lymphoma LYCODOXMR I
vincristine, doxorubicin, methotrexate, leucovorin and rituximab

advanced indolent lymphoma using cyclophosphamide, vincristine and


vincristine (cont'd) injectable Lymphoma LYCVP I
prednisone
treatment of Hodgkin's Disease with cyclophosphamide, vinblastine,
vincristine (cont'd) injectable Lymphoma LYCVPPABO I
procarbazine and prednisone
treatment of advanced indolent lymphoma using cyclophosphamide,
vincristine (cont'd) injectable Lymphoma LYCVPR I
vincristine, prednisone and rituximab
treatment of lymphoma with dose-adjusted etoposide, doxorubicin,
vincristine (cont'd) injectable Lymphoma vincristine, cyclophosphamide, prednisone and rituximab with intrathecal LYEPOCHR I
methotrexate
vincristine (cont'd) injectable Lymphoma lymphoma palliative chemotherapy LYPALL I
SAIME alternating with SAVAC or SAVACM with filgrastim support at
TWO weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
vincristine (cont'd) injectable Sarcoma SAALT2W I
Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma
SAIME alternating with SAVAC or SAVACM with filgrastim support at
THREE weekly interval for newly diagnosed Ewing's Sarcoma/Ewing’s
vincristine (cont'd) injectable Sarcoma SAALT3W I
Family of Tumours, Desmoplastic Intra-Abdominal Small Round Blue Cell
Tumour or Rhabdomyosarcoma

* denotes change
Page 64 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES

vincristine (cont'd) injectable Sarcoma treatment of sarcomas with vincristine, doxorubicin and cyclophosphamide SAVAC I

Treatment of Sarcomas with Pelvic Primaries or Chemotherapy-Induced


vincristine (cont'd) injectable Sarcoma SAVACM I
Hematuria using Vincristine, Doxorubicin, Cyclophosphamide and Mesna

Adjuvant Therapy for Rhabdomyosarcoma using Vincristine, Dactinomycin


vincristine (cont'd) injectable Sarcoma SAVDC I
and Cyclophosphamide

Other tumour site


Not Otherwise
vincristine (cont'd) injectable code followed by I
Specified
‘NOS’ (e.g. LYNOS)

vinorelbine injectable Breast palliative therapy for metastatic breast cancer BRAVNAV I
combination with 3-weekly trastuzumab as palliative therapy for metastatic
vinorelbine injectable Breast BRAVTRVIN I
breast cancer
treatment of platinum resistant epithelial ovarian cancer with bevacizumab
vinorelbine injectable Gynecology GOOVBEVV I
and vinorelbine
palliative chemotherapy for re-treatment of ovarian, tubal, and peritoneal
vinorelbine injectable Gynecology GOOVVIN I
cancer
combination with cisplatin as treatment of advanced salivary gland
vinorelbine injectable Head and Neck HNSAVNP I
cancers with cisplatin and vinorelbine
adjuvant cisplatin and vinorelbine following resection of stage I, II and IIIA
vinorelbine (cont'd) injectable Lung LUAJNP I
non-small cell lung cancer
combination with cisplatin as treatment for advanced non-small cell lung
vinorelbine (cont'd) injectable Lung LUAVNP I
cancer
vinorelbine (cont'd) injectable Lung advanced non-small cell lung cancer in elderly patients LUAVVIN I
vinorelbine (cont'd) injectable Lung malignant mesothelioma LUMMVIN I
Treatment of Relapsed or Refractory Hodgkin Lymphoma with
vinorelbine (cont'd) injectable Lymphoma LYGVLD I
Gemcitabine, Vinorelbine and Doxorubicin Pegylated Liposomal
pediatric patients treated on the COG protocol AHOD0521 for
vinorelbine (cont'd) injectable Pediatric I
refractory/recurrent Hodgkin’s disease

treatment of pediatric patients with relapsed Hodgkin lymphoma with a


vinorelbine (cont'd) injectable Pediatric I
combination of ifosfamide, mesna, gemcitabine and vinorelbine (IGEV)

treatment of recurrent/refractory rhabdomysarcoma in pediatric patients


vinorelbine (cont'd) injectable Pediatric with cyclophosphamide, vinorelbine and temsirolimus on the COG I
ARST0921 protocol
vismodegib capsule Skin & Melanoma treatment of metastatic or locally advanced basal cell carcinoma SMAVVIS I

transarterial radioembolisation of hepatocellular carcinoma with portal


yttrium-90 injectable Gastrointestinal GIYTT I
venous invasion or T3 tumours, and metastatic neuroendocrine tumours

adjuvant therapy for breast cancer in post-menopausal women using


zoledronic acid injectable Breast BRAJZOL5 I
zoledronic acid
adjuvant therapy for breast cancer in post-menopausal women using 3-
BRAJZOL2 I
monthly zoledronic acid
treatment of acute bone pain secondary to breast cancer metastases
BRAVZOL I
using IV zoledronic acid
zoledronic acid injectable Breast treatment of multiple myeloma with zoledronic acid MYZOL I

* denotes change
Page 65 of 65
BC Cancer Benefit Drug List
April 2022

DOSAGE TUMOUR PROTOCOL


DRUG APPROVED INDICATIONS CLASS NOTES
FORM SITE CODES
Protocol Code Definitions
Bone Marrow Transplantation BMT
Breast BR
Gastrointestinal GI
Genitourinary GU
Gynecologic GO
Head and Neck HN
Kaposi’s sarcoma KS
Leukemia LK
Lung LU
Lymphoma LY
Miscellaneous Origin MO
Myeloma MY
Neuro-Oncology CN
Ocular OC
Primary Unknown PU
Sarcoma SA
Skin & Melanoma SM

* denotes change

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