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Benefit Drug List
Benefit Drug List
Benefit Drug List
DEFINITIONS
Class I Reimbursed for active cancer or approved treatment or approved indication only.
Reimbursed for approved indications only. Completion of the BC Cancer Compassionate Access Program Application (formerly Undesignated Indication Form) is necessary to provide
Restricted Funding (R)
the appropriate clinical information for each patient.
NOTES
1. BC Cancer will reimburse, to the Communities Oncology Network hospital pharmacy, the actual acquisition cost of a Benefit Drug, up to the maximum price as determined by BC Cancer, based on the current brand
and contract price. Please contact the OSCAR Hotline at 1-888-355-0355 if more information is required.
2. Not Otherwise Specified (NOS) code only applicable to Class I drugs where indicated.
3. Intrahepatic use of chemotherapy drugs is not reimbursable unless specified.
4. For queries regarding other indications not specified, please contact the BC Cancer Compassionate Access Program Office at 604.877.6000 x 6277 or cap_bcca@bccancer.bc.ca
* denotes change
Page 2 of 65
BC Cancer Benefit Drug List
April 2022
anastrozole (cont'd) tablet Gynecology therapy for advanced ovarian cancer using an aromatase inhibitor GOOVAI I
Treatment of Metastatic Castration Sensitive Prostate Cancer using
apalutamide tablet Genitourinary UGUMCSPAPA R
Apalutamide
Treatment of Non- Metastatic Castration Resistant Prostate Cancer Using
apalutamide tablet Genitourinary UGUPAPA R
Apalutamide
first-line induction and consolidation therapy of acute promyelocytic
arsenic trioxide injectable Leukemia & BMT LKATOATRA I
leukemia using arsenic trioxide and tretinoin
first-line induction and consolidation therapy of acute promyelocytic
arsenic trioxide injectable Leukemia & BMT LKATOP I
leukemia using arsenic trioxide, tretinoin and daunorubicin
asparaginase
injectable Leukemia & BMT LKNOS, LYNOS I
(KIDROLASE®)
* denotes change
Page 3 of 65
BC Cancer Benefit Drug List
April 2022
bendamustine (cont'd) injectable Lymphoma treatment of Non-Hodgkin Lymphoma with bendamustine and rituximab LYBENDR I
bendamustine injectable Lymphoma treatment of relapsed chronic lymphocytic leukemia with bendamustine LYCLLBEND I
* denotes change
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BC Cancer Benefit Drug List
April 2022
* denotes change
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BC Cancer Benefit Drug List
April 2022
cabozantinib tablet Gastrointestinal Treatment of Advanced Hepatocellular Carcinoma using Cabozantinib UGICABO R
cabozantinib tablet Genitourinary therapy for metastatic renal cell carcinoma using cabozantinib GUCABO I
* denotes change
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BC Cancer Benefit Drug List
April 2022
capecitabine tablet Breast therapy for metastatic breast cancer using capecitabine and lapatinib BRAVLCAP I
* denotes change
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BC Cancer Benefit Drug List
April 2022
carboplatin injectable Neuro-Oncology carboplatin and etoposide in the treatment of recurrent ependymoma CNCARV I
* denotes change
Page 8 of 65
BC Cancer Benefit Drug List
April 2022
second line treatment for epithelial ovarian cancer relapsing after primary
carboplatin (cont'd) injectable Gynecology GOOVPLDC I
treatment using pegylated liposomal doxorubicin (PLD) and carboplatin
carboplatin (cont'd) injectable Gynecology treatment of small-cell gynecologic cancer with cisplatin and etoposide GOSCPE I
carboplatin (cont'd) injectable Genitourinary palliative therapy for urothelial carcinoma using cisplatin and gemcitabine GUAVPG I
* denotes change
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BC Cancer Benefit Drug List
April 2022
carboplatin (cont'd) injectable Genitourinary therapy of genitourinary small cell tumors with a platin and etoposide GUSCPE I
therapy of genitourinary small cell tumors with a platin and etoposide with
carboplatin (cont'd) injectable Genitourinary GUSCPERT I
radiation
treatment of advanced squamous cell carcinoma of the head and neck
carboplatin (cont'd) injectable Head and Neck HNAVFUP I
cancer using fluorouracil and platinum
treatment for unresectable, locoregionally recurrent or metastatic
carboplatin (cont'd) injectable Head and Neck squamous cell carcinoma of the head and neck using paclitaxel and HNAVPC I
cisplatin or carboplatin
* denotes change
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BC Cancer Benefit Drug List
April 2022
carboplatin (cont'd) injectable Lung treatment of thymoma with cisplatin and etoposide LUOTPE I
carboplatin (cont'd) injectable Lung treatment of thymoma using cisplatin and etoposide with radiation therapy LUOTPERT I
* denotes change
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BC Cancer Benefit Drug List
April 2022
cemiplimab injectable Skin & Melanoma Cemiplimab for Treatment of Cutaneous Squamous Cell Carcinoma SMAVCEM I
treatment of ALK-positive advanced non-small cell lung cancer (NSCLC)
ceritinib capsule Lung LUAVCER I
with ceritinib
palliative third line treatment of metastatic colorectal cancer with wild-type
cetuximab injectable Gastrointestinal GIAVCETIR I
KRAS using cetuximab and irinotecan
combined cetuximab and radiation treatment for locally advanced
cetuximab (cont'd) injectable Head and Neck HNLACETRT I
squamous cell carcinoma of the head and neck
chlorambucil tablet Lymphoma low grade lymphoma and chronic lymphocytic leukemia LYCHLOR I
chlorambucil tablet Lymphoma treatment of indolent B-cell lymphoma with chlorambucil and rituximab LYCHLRR I
chlorambucil tablet Lymphoma treatment of chronic lymphocytic leukemia with chlorambucil and rituximab LYCLLCHLR I
* denotes change
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BC Cancer Benefit Drug List
April 2022
combined modality curative therapy for carcinoma of the anal canal using
cisplatin (cont'd) injectable Gastrointestinal GIFUPART I
cisplatin, infusional fluorouracil and radiation therapy
adjuvant chemotherapy of gastric cancer patients with completely
cisplatin (cont'd) injectable Gastrointestinal resected gastric cancer using cisplatin and capecitabine and radiation GIGAJCPRT I
therapy
palliative therapy of metastatic or locally advanced anal squamous cell
cisplatin (cont'd) injectable Gastrointestinal GIGAVCC I
carcinoma using cisplatin and capecitabine
Palliative Treatment of Metastatic or Locally Advanced Gastric,
cisplatin (cont'd) injectable Gastrointestinal Gastroesophageal Junction or Esophageal Adenocarcinoma using GIGAVCCT I
Cisplatin, Capecitabine and Trastuzumab
palliative treatment of metastatic or inoperable, locally advanced gastric or
cisplatin (cont'd) injectable Gastrointestinal gastroesophageal junction adenocarcinoma using cisplatin, infusional GIGAVCFT I
fluorouracil and trastuzumab
treatment of operable cancer of the stomach, stomach-esophagus
cisplatin (cont'd) injectable Gastrointestinal junction or lower 1/3 esophagus, given before and after surgery, using GIGECC I
epirubicin, cisplatin and capecitabine
cisplatin (cont'd) injectable Gastrointestinal palliative therapy of neuroendocrine tumours using cisplatin and etoposide GIPE I
* denotes change
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BC Cancer Benefit Drug List
April 2022
cisplatin (cont'd) injectable Gynecology treatment of small-cell gynecologic cancer with cisplatin and etoposide GOSCPE I
cisplatin (cont'd) injectable Genitourinary adjuvant therapy for urothelial carcinoma using cisplatin and gemcitabine GUAJPG I
cisplatin (cont'd) injectable Genitourinary palliative therapy for urothelial carcinoma using cisplatin and gemcitabine GUAVPG I
curative therapy for germ cell cancer using bleomycin, etoposide and
cisplatin (cont'd) injectable Genitourinary GUBEP I
cisplatin
treatment of locally advanced bladder cancer with weekly cisplatin and
cisplatin (cont'd) injectable Genitourinary GUBPWRT I
concurrent radiation
treatment of metastatic adrenalcortical cancer with doxorubicin, etoposide,
cisplatin (cont'd) injectable Genitourinary GUEDPM I
cisplatin and mitotane
cisplatin (cont'd) injectable Genitourinary therapy for nonseminoma germ cell cancer using etoposide-cisplatin GUEP I
cisplatin (cont'd) injectable Genitourinary therapy of genitourinary small cell tumors with a platin and etoposide GUSCPE I
therapy of genitourinary small cell tumors with a platin and etoposide with
cisplatin (cont'd) injectable Genitourinary GUSCPERT I
radiation
advanced therapy for relapsed testicular germ cell cancer using paclitaxel,
cisplatin (cont'd) injectable Genitourinary GUTIP I
ifosfamide and cisplatin
consolidation/ salvage treatment for germ cell cancer using vinblastine,
cisplatin (cont'd) injectable Genitourinary GUVEIP I
cisplatin, ifosfamide and mesna
nonseminoma consolidation/salvage protocol using etoposide, cisplatin,
cisplatin (cont'd) injectable Genitourinary GUVIP2 I
ifosfamide, mesna
treatment of advanced squamous cell carcinoma of the head and neck
cisplatin (cont'd) injectable Head and Neck HNAVFUP I
cancer using fluorouracil and platinum
palliative chemotherapy for advanced head and neck squamous cell
cisplatin (cont'd) injectable Head and Neck HNAVP I
carcinoma with weekly cisplatin
treatment for unresectable, locoregionally recurrent or metastatic
cisplatin (cont'd) injectable Head and Neck squamous cell carcinoma of the head and neck using paclitaxel and HNAVPC I
cisplatin or carboplatin
* denotes change
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BC Cancer Benefit Drug List
April 2022
* denotes change
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BC Cancer Benefit Drug List
April 2022
cisplatin (cont'd) injectable Lung treatment of malignant mesothelioma with platinum and gemcitabine LUMMPG I
cisplatin (cont'd) injectable Lung treatment of malignant mesothelioma with platinum and pemetrexed LUMMPP I
cisplatin (cont'd) injectable Lung treatment of thymoma with platinum, doxorubicin and cyclophosphamide LUOTPAC I
cisplatin (cont'd) injectable Lung treatment of thymoma with cisplatin and etoposide LUOTPE I
cisplatin (cont'd) injectable Lung treatment of thymoma using cisplatin and etoposide with radiation therapy LUOTPERT I
cisplatin (cont'd) injectable Lymphoma treatment of lymphoma with gemcitabine, dexamethasone and platinum LYGDP I
cisplatin (cont'd) injectable Sarcoma adjuvant therapy for osteosarcoma using doxorubicin and cisplatin SAAJAP I
cisplatin (cont'd) injectable Sarcoma therapy of advanced osteosarcoma using doxorubicin and cisplatin SAAVAP I
* denotes change
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April 2022
* denotes change
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BC Cancer Benefit Drug List
April 2022
cyclophosphamide (cont'd) tablet, injectable Lung treatment of thymoma with platinum, doxorubicin and cyclophosphamide LUOTPAC I
* denotes change
Page 18 of 65
BC Cancer Benefit Drug List
April 2022
cyclophosphamide (cont'd) tablet, injectable Sarcoma treatment of sarcomas with vincristine, doxorubicin and cyclophosphamide SAVAC I
* denotes change
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BC Cancer Benefit Drug List
April 2022
cytarabine injectable Lymphoma treatment of lymphoma using intrathecal methotrexate and cytarabine LYIT I
* denotes change
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BC Cancer Benefit Drug List
April 2022
dacarbazine (cont'd) injectable Sarcoma high dose single agent dacarbazine for metastatic soft tissue sarcoma SADTIC I
therapy for metastatic malignant melanoma using high dose single agent
dacarbazine injectable Skin & Melanoma SMDTIC I
dacarbazine
Therapy for Moderate Low-Risk Gestational Trophoblastic Cancer using GOTDMR (previously
dactinomycin (cont'd) injectable Gynecology I
Dactinomycin and Methotrexate GOTDLR)
* denotes change
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BC Cancer Benefit Drug List
April 2022
degarelix injectable Genitourinary therapy for prostate cancer using LHRH antagonist GUPLHRHA I
neoadjuvant use in patients with non-metastatic operable giant cell tumour
denosumab (XGEVA®) injectable Sarcoma SANADENO I
of the bone
Therapy for Metastatic Castration-Sensitive Prostate Cancer using
dexamethasone tablet Genitourinary UGUMCSPABI R
Abiraterone and Prednisone
Palliative Therapy for Metastatic Castration Resistant Prostate Cancer
dexamethasone tablet Genitourinary UGUPABI R
Using Abiraterone and prednisone
dexamethasone (cont'd) tablet Lymphoma treatment of lymphoma with gemcitabine, dexamethasone and platinum LYGDP I
treatment of lymphoma with gemcitabine, dexamethasone and platinum
dexamethasone Lymphoma LYGDPR I
tablet with rituximab
treatment of newly diagnosed nasal, extranodal natural killer (NK) or T-cell Not reimbursed for:
dexamethasone (cont'd) tablet Lymphoma lymphoma, stage IE to IIE using concurrent radiation and weekly cisplatin LYVIPDRT I anti-emetic treatment, steroid
followed by etoposide, ifosfamide, cisplatin and dexamethasone replacement therapy, pre-taxane
use, or appetite stimulation
Bortezomib, Lenalidomide and Dexamethasone for Previously Untreated
dexamethasone (cont'd) tablet Myeloma UMYBLDF R
Multiple Myeloma
* denotes change
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April 2022
* denotes change
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BC Cancer Benefit Drug List
April 2022
docetaxel (cont'd) injectable Genitourinary intravesical use for bladder cancer if BCG and mitomycin C not available GUNOS I
docetaxel (cont'd) injectable Genitourinary palliative therapy for metastatic hormone refractory prostate cancer GUPDOC I
* denotes change
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BC Cancer Benefit Drug List
April 2022
doxorubicin injectable Breast palliative therapy for metastatic breast cancer using weekly doxorubicin BRAVA7 I
* denotes change
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BC Cancer Benefit Drug List
April 2022
doxorubicin (cont'd) injectable Genitourinary palliative therapy for advanced adrenal cortical cancer using doxorubicin GUAVD I
treatment of metastatic adrenalcortical cancer with doxorubicin, etoposide, Not reimbursed for bladder
doxorubicin (cont'd) injectable Genitourinary GUEDPM I
cisplatin and mitotane instillations
therapy for transitional cell cancers of the urothelium using methotrexate,
doxorubicin (cont'd) injectable Genitourinary GUMVAC I
vinblastine, doxorubicin and cisplatin
doxorubicin (cont'd) injectable Gynecology for use in patients with advanced endometrial cancer GOENDD I
doxorubicin (cont'd) injectable Gynecology for use in patients with advanced uterine sarcoma GOSAD I
doxorubicin (cont'd) injectable Head and Neck palliative therapy for advanced thyroid cancers using doxorubicin HNOTAVD I
palliative therapy for advanced salivary gland cancers using
doxorubicin (cont'd) injectable Head and Neck HNSAVFAC I
cyclophosphamide, doxorubicin and fluorouracil
treatment of advanced salivary gland cancers with platinum, doxorubicin
doxorubicin (cont'd) injectable Head and Neck HNSAVPAC I
and cyclophospahmide
treatment of thymoma/thymic carcinoma with cyclophosphamide,
doxorubicin (cont'd) injectable Lung LUOTCAV I
doxorubicin and vincristine
doxorubicin (cont'd) injectable Lung treatment of thymoma with platinum, doxorubicin, and cyclophosphamide LUOTPAC I
* denotes change
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BC Cancer Benefit Drug List
April 2022
doxorubicin (cont'd) injectable Sarcoma adjuvant therapy for osteosarcoma using doxorubicin and cisplatin SAAJAP I
doxorubicin (cont'd) injectable Sarcoma therapy of advanced osteosarcoma using doxorubicin and cisplatin SAAVAP I
doxorubicin (cont'd) injectable Sarcoma treatment of sarcomas with vincristine, doxorubicin and cyclophosphamide SAVAC I
* denotes change
Page 27 of 65
BC Cancer Benefit Drug List
April 2022
epirubicin (cont'd) injectable Genitourinary intravesical use for bladder cancer if BCG and mitomycin C not available GUNOS I
eribulin injectable Breast Palliative Therapy for Metastatic Breast Cancer using Eribulin BRAVERIB I
eribulin injectable Sarcoma Palliative Therapy for Metastatic Sarcoma using Eribulin SAAVERIB I
erlotinib tablet Lung second or third line treatment of advanced non-small cell lung cancer LUAVERL I
* denotes change
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BC Cancer Benefit Drug List
April 2022
capsule/ treatment of locally advanced non-small cell lung cancer using alternative
etoposide (cont'd) Lung LULAPE2RT I
injectable dosing of cisplatin and etoposide with radiation therapy
* denotes change
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BC Cancer Benefit Drug List
April 2022
* denotes change
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BC Cancer Benefit Drug List
April 2022
everolimus tablet Breast therapy for advanced breast cancer using everolimus and exemestane BRAVEVEX I
everolimus tablet Genitourinary therapy for advanced renal cancer using everolimus GUEVER I
treatment of advanced neuroendocrine tumours of lung origin (non-
everolimus (cont'd) tablet Lung ULUNETEV R
functional) using everolimus
neoadjuvant or adjuvant therapy for breast cancer using exemestane in
exemestane tablet Breast BRAJEXE I
postmenopausal women
exemestane tablet Breast therapy for advanced breast cancer using everolimus and exemestane BRAVEVEX I
fludarabine injectable/ tablet Lymphoma chronic lymphocytic leukemia or low grade lymphoma LYFLU I
fludarabine injectable/ tablet Lymphoma treatment of relapsed indolent lymphoma with fludarabine and rituximab LYFLUDR I
fludarabine injectable/ tablet Pediatric pediatric patients with AML treated on the CCG-2961 study
I
treatment of metastatic adrenalcortical cancer with doxorubicin, etoposide,
fludrocortisone tablet Genitourinary GUEDPM I
cisplatin and mitotane
fludrocortisone (cont'd) tablet Genitourinary mineralocorticoid deficiency associated with mitotane use GUMITO I
* denotes change
Page 31 of 65
BC Cancer Benefit Drug List
April 2022
adjuvant combination chemotherapy for stage III and stage IIB colon
fluorouracil (cont'd) injectable Gastrointestinal GIAJFFOX I
cancer using oxaliplatin, fluorouracil and folinic acid (leucovorin)
* denotes change
Page 32 of 65
BC Cancer Benefit Drug List
April 2022
combined modality curative therapy for carcinoma of the anal canal using
fluorouracil (cont'd) injectable Gastrointestinal GIFUPART I
cisplatin, infusional fluorouracil and radiation therapy
adjuvant chemotherapy in gastric cancer patients with D2 resection (node
fluorouracil (cont'd) injectable Gastrointestinal negative) or ineligible for adjuvant chemoradiation using oxaliplatin, GIGAJFFOX I
fluorouracil, and leucovorin
palliative treatment of metastatic or inoperable, locally advanced gastric or
fluorouracil (cont'd) injectable Gastrointestinal gastroesophageal junction adenocarcinoma using cisplatin, infusional GIGAVCFT I
fluorouracil and trastuzumab
Palliative Treatment of Metastatic or Locally Advanced Gastric,
fluorouracil (cont'd) injectable Gastrointestinal Gastroesophageal Junction or Esophageal Carcinoma using Oxaliplatin, GIGAVFFOX I
Fluorouracil and Leucovorin
palliative treatment of metastatic or locally advanced HER-2 positive
fluorouracil (cont'd) injectable Gastrointestinal gastric, gastroesophageal junction, or esophageal adenocarcinoma using GIGAVFFOXT I
oxaliplatin, fluorouracil, leucovorin, and trastuzumab
perioperative treatment of resectable adenocarcinoma of the stomach,
fluorouracil (cont'd) injectable Gastrointestinal gastroesophageal junction or lower 1/3 esophagus using docetaxel, GIGFLODOC I
oxaliplatin, infusional fluorouracil, and leucovorin
* denotes change
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BC Cancer Benefit Drug List
April 2022
fluorouracil eyedrops Ocular Topical Therapy for Ocular Malignancies using Fluorouracil Eye Drops OCFU I
gemcitabine injectable Breast treatment of metastatic breast cancer using gemcitabine and paclitaxel BRAVGEMT I
gemcitabine (cont'd) injectable Gastrointestinal adjuvant chemotherapy for pancreatic adenocarcinoma using gemcitabine GIPAJGEM I
* denotes change
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BC Cancer Benefit Drug List
April 2022
gemcitabine (cont'd) injectable Genitourinary adjuvant therapy for urothelial carcinoma using cisplatin and gemcitabine GUAJPG I
gemcitabine (cont'd) injectable Genitourinary combination with cisplatin as neoadjuvant therapy for urothelial carcinoma GUNAJPG I
gemcitabine (cont'd) injectable Genitourinary palliative therapy for germ cell cancers using paclitaxel and gemcitabine GUTAXGEM I
gemcitabine (cont'd) injectable Lung treatment of malignant mesothelioma with platinum and gemcitabine LUMMPG I
gemcitabine (cont'd) injectable Lymphoma treatment of lymphoma with gemcitabine, dexamethasone and platinum LYGDP I
combination with docetaxel as second or third line therapy for soft tissue
gemcitabine (cont'd) injectable Sarcoma SAAVGEMD I
sarcomas
Treatment of Acute Myeloid Leukemia using Gemtuzumab Ozogamicin
gemtuzumab ozogamicin injectable Leukemia & BMT LKGEMOZ I
with Induction and Consolidation Chemotherapy
Therapy of Relapsed or Refractory FLT3+ Acute Myeloid Leukemia using
gilteritinib tablet Leukemia & BMT ULKAMLGIL R
Gilteritinib
* denotes change
Page 35 of 65
BC Cancer Benefit Drug List
April 2022
long acting neoadjuvant or adjuvant therapy for breast cancer using a LHRH agonist
goserelin Breast BRAJLHRHT I
injectable and tamoxifen
long acting therapy for advanced breast cancer using a LHRH agonist and an
goserelin (cont'd) Breast BRAVLHRHA I
injectable aromatase inhibitor
long acting combination therapy with tamoxifen palliative therapy for metastatic breast
goserelin (cont'd) Breast BRAVLHRHT I
injectable cancer
long acting therapy of advanced breast cancer using palbociclib and aromatase Not reimbursed for endometriosis
goserelin (cont'd) Breast BRAVPALAI I
injectable inhibitor with or without LHRH agonist
long acting Therapy of Advanced Breast Cancer using Palbociclib and Fulvestrant
goserelin (cont'd) Breast BRAVPBFLV I
injectable with or without LHRH Agonist
long acting Therapy of Advanced Breast Cancer using Ribociclib and Fulvestrant with
goserelin (cont'd) Breast BRAVRBFLV I
injectable or without LHRH Agonist
long acting therapy of advanced breast cancer using ribociclib and aromatase
goserelin (cont'd) Breast BRAVRIBAI I
injectable inhibitor with or without LHRH agonist
long acting
goserelin (cont'd) Genitourinary therapy for prostate cancer using LHRH agonist GUPLHRH I
injectable
treatment of hemophagocytic lymphohistiocytosis with etoposide,
hydrocortisone tablet, injectable Lymphoma HLHETCSPA I
dexamethasone and cycloSPORINE
Myeloid neoplasms, including but not limited to: Acute myeloid leukemia,
Myelodysplastic syndromes (e.g. Refractory anemia), Myeloproliferative
hydroxyurea capsule Leukemia & BMT LKNOS I
disease (e.g. Chronic myeloid leukemia, Polycythemia, Essential
thrombocythemia)
Lymphoid neoplasms, including but not limited to: Lymphoproliferative
hydroxyurea capsule Lymphoma LYNOS I
disease, Myeloma
ibritumomab 90Y Palliative therapy for lymphoma using radioimmunotherapy: rituximab-
injectable Lymphoma LYRITZ I
(ZEVALIN®) priming for ibritumomab 90Y (ZEVALIN®)
treatment of previously untreated chronic lymphocytic leukemia or small
ibrutinib capsule Lymphoma ULYFIBRU R
lymphocytic lymphoma using ibrutinib
treatment of relapsed or refractory chronic lymphocytic leukemia or small
ibrutinib capsule Lymphoma LYIBRU I
lymphocytic lymphoma using ibrutinib
ibrutinib (cont'd) capsule Lymphoma treatment of relapsed/refractory mantle-cell lymphoma using ibrutinib LYMIBRU I
* denotes change
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April 2022
* denotes change
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April 2022
* denotes change
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BC Cancer Benefit Drug List
April 2022
irinotecan (cont'd) injectable Gastrointestinal palliative chemotherapy of metastatic colorectal cancer using irinotecan GIIR I
isotretinoin (ACCUTANE) capsule Pediatric pediatric patients with high risk neuroblastoma I
lanreotide injectable Neuro-Oncology treatment of growth hormone secreting pituitary adenoma using lanreotide CNLAN I
lapatinib tablet Breast therapy for metastatic breast cancer using capecitabine and lapatinib BRAVLCAP I
* denotes change
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BC Cancer Benefit Drug List
April 2022
* denotes change
Page 40 of 65
BC Cancer Benefit Drug List
April 2022
adjuvant combination chemotherapy for Stage III and Stage IIB colon
leucovorin calcium tablet, injectable Gastrointestinal GIAJFFOX I
cancer using oxaliplatin, fluorouracil and folinic acid (Leucovorin)
* denotes change
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BC Cancer Benefit Drug List
April 2022
Therapy for Moderate Low-Risk Gestational Trophoblastic Cancer using GOTDMR (previously
leucovorin calcium (cont'd) tablet, injectable Gynecology I
Dactinomycin and Methotrexate GOTDLR)
fluorouracil and leucovorin for recurrent head and neck cancer (squamous
leucovorin calcium (cont'd) tablet, injectable Head and Neck HNAVFUFA I
cell carcinoma)
fluorouracil and leucovorin for recurrent head and neck cancer
leucovorin calcium (cont'd) tablet, injectable Head and Neck HNNAVFUFA I
(nasopharyngeal)
* denotes change
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BC Cancer Benefit Drug List
April 2022
injectable, long neoadjuvant or adjuvant therapy for breast cancer using a LHRH agonist
leuprolide Breast BRAJLHRHT I
acting injectable and tamoxifen
injectable, long therapy for advanced breast cancer using a LHRH agonist and an
leuprolide (cont'd) Breast BRAVLHRHA I
acting injectable aromatase inhibitor
injectable, long combination therapy with tamoxifen palliative therapy for metastatic breast
leuprolide Breast BRAVLHRHT I
acting injectable cancer
Not reimbursed for endometriosis.
injectable, long therapy of advanced breast cancer using palbociclib and aromatase Leuprolide acetate IM (LUPRON®)
leuprolide (cont'd) Breast BRAVPALAI I
acting injectable inhibitor with or without LHRH agonist and SC (ELIGARD®) injectables
are both reimbursable for prostate
injectable, long Therapy of Advanced Breast Cancer using Palbociclib and Fulvestrant cancer indications (GUPLHRH).
leuprolide Breast BRAVPBFLV I
acting injectable with or without LHRH Agonist
injectable, long Therapy of Advanced Breast Cancer using Ribociclib and Fulvestrant with
leuprolide Breast BRAVRBFLV I
acting injectable or without LHRH Agonist
injectable, long therapy of advanced breast cancer using ribociclib and aromatase
leuprolide Breast BRAVRIBAI I
acting injectable inhibitor with or without LHRH agonist
injectable, long
leuprolide Genitourinary therapy for prostate cancer using LHRH agonist GUPLHRH I
acting injectable
lomustine capsule Neuro-Oncology lomustine for treatment of recurrent malignant brain tumors CNCCNU I
adjuvant lomustine, cisplatin and vincristine in adult high-risk
lomustine capsule Neuro-Oncology CNCCV I
medulloblastoma or other primitive neuroectodermal tumour
modified PCV chemotherapy of brain tumours using procarbazine,
lomustine (cont'd) capsule Neuro-Oncology CNMODPCV I
lomustine and vincristine
lomustine (cont'd) capsule Lymphoma lymphoma palliative chemotherapy LYPALL I
megestrol tablet Breast breast cancer BRAVMEG I Not reimbursed for appetite
stimulation or symptom
megestrol tablet Gynecology non-aromatase inhibitor hormonal treatment of endometrial cancer GOENDH I management
* denotes change
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BC Cancer Benefit Drug List
April 2022
melphalan tablet, injectable Myeloma treatment of multiple myeloma using melphalan and prednisone MYMP I
* denotes change
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BC Cancer Benefit Drug List
April 2022
mesna injectable 3-day ifosfamide for use in patients with advanced soft tissue sarcoma SAAVI3 I
Sarcoma
3-day etoposide & ifosfamide-mesna for patients with advanced soft
mesna injectable SAAVIME3 I
Sarcoma tissue or bony sarcomas
mesna (cont'd) injectable Sarcoma etoposide, ifosfamide-mesna (SAIME) for use in sarcomas SAIME I
Approved for use ONLY as an uro-
Treatment of Sarcomas with Pelvic Primaries or Chemotherapy-Induced protector for ifosfamide or high
mesna (cont'd) injectable Sarcoma SAVACM I
Hematuria using Vincristine, Doxorubicin, Cyclophosphamide and Mesna dose cyclophosphamide
mesna dosage modification for hematuria secondary to
mesna (cont'd) injectable Supportive Care SCMESNA I
oxazaphosphorines
Therapy for Moderate Low-Risk Gestational Trophoblastic Cancer using GOTDMR (previously
methotrexate (cont'd) tablet, injectable Gynecology I
Dactinomycin and Methotrexate GOTDLR)
* denotes change
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April 2022
methotrexate (cont'd) tablet, injectable Lymphoma treatment of lymphoma using intrathecal methotrexate and cytarabine LYIT I
* denotes change
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April 2022
nilotinib tablet Leukemia & BMT Treatment of Chronic Myeloid Leukemia using Nilotinib LKCMLN I
prostate carcinoma patients who are intolerant to bicalutamide or Not reimbursed for vasomotor
nilutamide tablet Genitourinary GUPNSAA I
flutamide, at 150 mg po daily symptoms (hot flashes)
Maintenance Treatment of Newly Diagnosed Platinum Responsive
niraparib capsule Gynecology UGOOVFNIRM R
Epithelial Ovarian Cancer using Niraparib
Maintenance Treatment of Relapsed Platinum Sensitive and Responsive
niraparib capsule Gynecology UGOOVNIRAM R
Epithelial Ovarian Cancer using Niraparib
treatment of metastatic or advanced renal cell carcinoma using ipilimumab
nivolumab injectable Genitourinary GUAVIPNI I
and nivolumab
* denotes change
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April 2022
nivolumab injectable Skin & Melanoma treatment of unresectable or metastatic melanoma using nivolumab SMAVNIV I
* denotes change
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BC Cancer Benefit Drug List
April 2022
* denotes change
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BC Cancer Benefit Drug List
April 2022
paclitaxel injectable Breast treatment of metastatic breast cancer using gemcitabine and paclitaxel BRAVGEMT I
* denotes change
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BC Cancer Benefit Drug List
April 2022
paclitaxel (cont'd) injectable Gynecology primarily advanced or recurrent endometrial cancer GOENDCAT I
primary treatment of invasive epithelial ovarian, fallopian tube and primary
paclitaxel (cont'd) injectable Gynecology peritoneal cancer with high risk of relapse using bevacizumab, carboplatin GOOVCATB I
and paclitaxel
paclitaxel (cont'd) injectable Genitourinary palliative therapy for germ cell cancers using paclitaxel and gemcitabine GUTAXGEM I
advanced therapy for relapsed testicular germ cell cancer using paclitaxel,
paclitaxel (cont'd) injectable Genitourinary GUTIP I
ifosfamide and cisplatin
treatment for unresectable, locoregionally recurrent or metastatic
paclitaxel (cont'd) injectable Head and Neck squamous cell carcinoma of the head and neck using paclitaxel and HNAVPC I
cisplatin or carboplatin
* denotes change
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BC Cancer Benefit Drug List
April 2022
pazopanib tablet Genitourinary palliative therapy for renal cell carcinoma using pazopanib GUPAZO I
* denotes change
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BC Cancer Benefit Drug List
April 2022
peginterferon alfa-2a injectable Leukemia & BMT therapy of chronic myeloid neoplasms and hypereosinophilic syndrome LKPEGIFN I
* denotes change
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BC Cancer Benefit Drug List
April 2022
pembrolizumab (cont'd) injectable Skin & Melanoma treatment of unresectable or metastatic melanoma using pembrolizumab SMAVPEM I
pemetrexed (cont'd) injectable Lung treatment of malignant mesothelioma with platinum and pemetrexed LUMMPP I
pomalidomide capsule Myeloma therapy of multiple myeloma using pomalidomide with dexamethasone UMYPOMDEX R
prednisone tablet Genitourinary palliative therapy for metastatic hormone refractory prostate cancer GUPDOC I
* denotes change
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BC Cancer Benefit Drug List
April 2022
prednisone (cont'd) tablet Myeloma treatment of multiple myeloma using melphalan and prednisone MYMP I
treatment of multiple myeloma using melphalan, prednisone and weekly
prednisone (cont'd) tablet Myeloma bortezomib with the option of substituting cyclophosphamide for MYMPBOR I
melphalan
* denotes change
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BC Cancer Benefit Drug List
April 2022
procarbazine capsule Neuro-Oncology standard procarbazine for second-line treatment of recurrent brain tumor CNPROC I
radio- therapy for metastatic castration resistant prostate cancer using radium-
radium-223 Genitourinary GUPRAD I
pharmaceutical 223
adjuvant combination chemotherapy for node-positive colon cancer using
raltitrexed injectable Gastrointestinal oxaliplatin and raltitrexed in patients intolerant to fluorouracil or GIAJRALOX I
capecitabine
Palliative Therapy of Metastatic Colorectal Cancer using Irinotecan and
GIAVRALIR I
Raltitrexed in Patients Intolerant to Fluorouracil or Capecitabine
Palliative Therapy of Metastatic Colorectal Cancer using Oxaliplatin and
GIAVRALOX I
Raltitrexed in Patients Intolerant to Fluorouracil or Capecitabine
unresectable or metastatic colorectal adenocarcinoma for patients with
raltitrexed injectable Gastrointestinal GIRALT I
previous fluorouracil toxicity
second-line therapy for metastatic or locally advanced gastric or
ramucirumab injectable Gastrointestinal gastroesophageal junction cancer using weekly paclitaxel and GIGAVRAMT I
ramucirumab
third line treatment of advanced gastrointestinal stromal cell tumours
regorafenib tablet Sarcoma SAAVGR I
(GIST's) using regorafenib
regorafenib tablet Gastrointestinal treatment of advanced hepatocellular carcinoma using regorafenib GIREGO I
* denotes change
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April 2022
IV / 1400 mg SC
rituximab (cont'd) Lymphoma combination with CVP for advanced stage indolent lymphoma at diagnosis LYCVPR I
injectable
* denotes change
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BC Cancer Benefit Drug List
April 2022
IV / 1400 mg SC
rituximab Lymphoma treatment of relapsed indolent lymphoma with fludarabine and rituximab LYFLUDR I
injectable
IV / 1400 mg SC treatment of lymphoma with gemcitabine, dexamethasone and platinum
rituximab (cont'd) Lymphoma LYGDPR I
injectable with rituximab
IV / 1400 mg SC Treatment of Primary and Secondary CNS Lymphoma with High-Dose
rituximab (cont'd) Lymphoma LYHDMRTEM I
injectable Methotrexate, Rituximab and Temozolomide
IV / 1600 mg SC treatment of relapsed/refractory chronic lymphocytic leukemia or small
rituximab (cont'd) Lymphoma LYIDELAR I
injectable lymphocytic lymphoma using idelalisib and rituximab
IV / 1400 mg SC treatment of Burkitt’s lymphoma and leukemia with ifosfamide, mesna, Note: Biosimilar rituximab
rituximab (cont'd) Lymphoma LYIVACR I
injectable etoposide, cytarabine and rituximab (RIXIMYO®, RUXIENCE®) is
Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma and funded for intravenous rituximab
IV / 1400 mg SC started on or after August 1st,
rituximab (cont'd) Lymphoma Not Eligible for Transplant using Polatuzumab Vedotin, Bendamustine and LYPOLABR* I
injectable 2020. RITUXAN® is funded for
Rituximab
intravenous rituximab started prior
IV / 1400 mg SC treatment of relapsed or refractory advanced stage aggressive B-cell non- to and continue beyond August
rituximab (cont'd) Lymphoma LYRICE I
injectable Hodgkin’s lymphoma with ifosfamide, carboplatin, etoposide and rituximab 1st, 2020.
follicular lymphoma progressive despite alkylating agents and purine
IV / 1400 mg SC analogues (fludarabine or cladribine), post-transplant lymphoproliferative
rituximab (cont'd) Lymphoma LYRITUX I
injectable disease, or newly diagnosed (within 6 months) asymptomatic advanced
follicular lymphoma
IV injectable palliative therapy for lymphoma using radioimmunotherapy: rituximab-
Lymphoma LYRITZ I
only priming for ibritumomab 90Y (ZEVALIN®)
IV / 1400 mg SC
rituximab (cont'd) Lymphoma maintenance treatment of indolent lymphoma LYRMTN I
injectable
IV / 1600 mg SC treatment of relapsed/refractory chronic lymphocytic leukemia or small
rituximab (cont'd) Lymphoma LYVENETOR I
injectable lymphocytic lymphoma using venetoclax and rituximab
pediatric patients treated on the COG protocols ANHL0221 for CD20
IV injectable positive post-transplant lymphoproliferative disease following solid organ
Pediatric I
only transplantation and ANHL01P1 for newly diagnosed advanced B-cell
leukemia/lymphoma
treatment of relapsed or refractory Peripheral T-Cell lymphoma (PTCL)
romidepsin injectable Lymphoma ULYROMI R
with romidepsin
ruxolitinib tablet Leukemia & BMT treatment of symptomatic myelofibrosis with ruxolitinib ULKMFRUX R
ruxolitinib tablet Leukemia & BMT treatment of polycythemia vera with ruxolitinib ULKPCVRUX R
* denotes change
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BC Cancer Benefit Drug List
April 2022
sorafenib tablet Genitourinary palliative therapy for renal cell carcinoma in patients after cytokine failure GUSORAF I
sorafenib tablet Leukemia & BMT therapy of acute myeloid leukemia using azacitidine and sorafenib LKAMLAS I
palliative therapy for pancreatic endocrine tumours using streptozocin and
streptozocin injectable Gastrointestinal GIENDO2 I
doxorubicin Approval from Health Canada
Other tumour site Special Access Programme is
Not Otherwise required for each patient
streptozocin injectable code followed by I
Specified
‘NOS’ (e.g. GINOS)
sunitinib capsule Gastrointestinal as palliative treatment of advance pancreatic neuroendocrine tumours GIPNSUNI I
palliative therapy for renal cell carcinoma in patients who are not suitable
sunitinib capsule Genitourinary GUSUNI I
candidates for interferon
second line treatment of advanced c-kit positive gastrointestinal stromal
sunitinib (cont'd) capsule Sarcoma SAAVGS I
cell tumours (GIST's) after imatinib
neoadjuvant or adjuvant therapy for breast cancer using a LHRH agonist
tamoxifen tablet Breast BRAJLHRHT I
and tamoxifen
tamoxifen tablet Breast neoadjuvant or adjuvant therapy for breast cancer using tamoxifen BRAJTAM I
tamoxifen (cont'd) tablet Breast palliative therapy for breast cancer using a LHRH agonist and tamoxifen BRAVLHRHT I
* denotes change
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BC Cancer Benefit Drug List
April 2022
* denotes change
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BC Cancer Benefit Drug List
April 2022
thyrotropin alfa injectable Head and Neck radioiodine imaging in patients with thyroid cancer and treatment HNOTTSH I
treatment of relapsed/progressive epithelial ovarian, fallopian tube or
topotecan injectable Gynecology GOOVTOP I
primary peritoneal cancer using topotecan
topotecan (cont'd) injectable Lung second line treatment of recurrent small cell lung cancer LUSCTOP I
topotecan (cont'd) injectable Pediatric pediatric sarcoma I
intermediate-risk (COG ANBL0532) and high risk (COG ANBL0531)
topotecan injectable Pediatric I
pediatric neuroblastoma
summary for treatment of recurrent/refractory neuroblastoma, ewing’s
topotecan injectable Sarcoma sarcoma, osteogenic sarcoma or rhabdomyosarcoma with SAAVTC I
topotecan/cyclophosphamide
adjuvant treatment of stage III and IV, BRAF-mutated, fully resected
trametinib tablet Skin & Melanoma SMAJDT I
melanoma using dabrafenib and trametinib
treatment of BRAF V600 mutation-positive unresectable or metastatic
trametinib tablet Skin & Melanoma SMAVDT I
melanoma using dabrafenib and trametinib
treatment of BRAF V600 mutation-positive unresectable or metastatic
trametinib tablet Skin & Melanoma SMAVTRA I
melanoma using trametinib
neoadjuvant or adjuvant therapy for breast cancer using doxorubicin and
trastuzumab injectable Breast BRAJACTT I
cyclophosphamide followed by paclitaxel and trastuzumab
neoadjuvant or adjuvant therapy for breast cancer using dose dense
trastuzumab therapy: doxorubicin and cyclophosphamide followed by paclitaxel and BRAJACTTG I
trastuzumab Note: Biosimilar trastuzumab
neoadjuvant or adjuvant therapy for breast cancer using carboplatin, (HERZUMA®, TRAZIMERA®) is
trastuzumab (cont'd) Injectable Breast BRAJDCARBT I
docetaxel and trastuzumab funded for treatment started on or
after February 1st, 2020, except
neoadjuvant or adjuvant therapy for breast cancer using fluorouracil, HERCEPTIN® continues to be
trastuzumab Injectable Breast BRAJFECDT I
epirubicin and cyclophosphamide followed by docetaxel and trastuzumab funded when trastuzumab is used
neoadjuvant or adjuvant therapy for breast cancer using trastuzumab, with pertuzumab for advanced
trastuzumab Injectable Breast BRAJTDC I breast cancer (BRAVPTRAD,
docetaxel and cyclophosphamide
BRAVPTRAT). HERCEPTIN® is
Adjuvant Therapy for Breast Cancer using Trastuzumab Following the
trastuzumab Injectable Breast BRAJTR I funded for treatment started prior
Completion of Chemotherapy (Sequential)
to February 1st, 2020.
adjuvant therapy for breast cancer using weekly paclitaxel and
trastuzumab injectable Breast BRAJTTW I
trastuzumab
palliative therapy for metastatic breast cancer using pertuzumab,
trastuzumab injectable Breast trastuzumab (Herceptin®) and docetaxel as first-line treatment for BRAVPTRAD I
advanced breast cancer
* denotes change
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BC Cancer Benefit Drug List
April 2022
single agent therapy for metastatic breast cancer progressing after 1 prior
trastuzumab injectable Breast regimens (e.g., taxane) and responding to trastuzumab in combination BRAVTR I
with paclitaxel, with paclitaxel and carboplatin, or with vinorelbine
combination with 3-weekly vinorelbine as palliative therapy for metastatic Note: Biosimilar trastuzumab
trastuzumab (cont'd) Injectable Breast BRAVTRVIN I (HERZUMA®, TRAZIMERA®) is
breast cancer
funded for treatment started on or
treatment of locally advanced breast cancer using doxorubicin and
trastuzumab (cont'd) Injectable Breast BRLAACDT I after February 1st, 2020, except
cyclophosphamide followed by docetaxel and trastuzumab
HERCEPTIN® continues to be
Palliative Treatment of Metastatic or Locally Advanced Gastric, funded when trastuzumab is used
trastuzumab (cont'd) Injectable Gastrointestinal Gastroesophageal Junction or Esophageal Adenocarcinoma using GIGAVCCT I with pertuzumab for advanced
Cisplatin, Capecitabine and Trastuzumab breast cancer (BRAVPTRAD,
palliative treatment of metastatic or inoperable, locally advanced gastric or BRAVPTRAT). HERCEPTIN® is
trastuzumab (cont'd) Injectable Gastrointestinal gastroesophageal junction adenocarcinoma using cisplatin, infusional GIGAVCFT I funded for treatment started prior
fluorouracil and trastuzumab to February 1st, 2020.
palliative treatment of metastatic or locally advanced gastric,
trastuzumab (cont'd) Injectable Gastrointestinal gastroesophageal junction, or esophageal adenocarcinoma using GIGAVCOXT I
capecitabine, oxaliplatin and trastuzumab
Palliative Treatment of Metastatic or Locally Advanced Gastric,
trastuzumab (cont'd) Injectable Gastrointestinal Gastroesophageal Junction or Esophageal Carcinoma using Oxaliplatin, GIGAVFFOXT I
Fluorouracil and Leucovorin
continuation of palliative treatment of metastatic or inoperable, locally
trastuzumab (cont'd) injectable Gastrointestinal advanced gastric or gastroesophageal junction adenocarcinoma using GIGAVTR I
trastuzumab
trastuzumab emtansine adjuvant therapy for breast cancer using trastuzumab emtansine
injectable Breast UBRAJKAD R
(KADCYLA) (KADCYLA)
trastuzumab emtansine palliative therapy for metastatic breast cancer using trastuzumab
injectable Breast BRAVKAD I
(KADCYLA) emtansine (KADCYLA)
treosulfan injectable Leukemia & BMT BMTNOS I
pre-conditioning therapy with treosulfan for pediatric patients at risk for
treosulfan (SAP) injectable Pediatric busulfan-related toxicity prior to hematopoietic stem cell transplantation for R
malignant conditions
tretinoin (VESANOID®) capsule Leukemia & BMT acute promyelocytic leukemia LKNOS I
tretinoin (VESANOID®) first-line induction and consolidation therapy of acute promyelocytic
capsule Leukemia & BMT LKATOATRA I
(cont'd) leukemia using arsenic trioxide and tretinoin
first-line induction and consolidation therapy of acute promyelocytic
tretinoin (VESANOID®) capsule Leukemia & BMT LKATOP I
leukemia using arsenic trioxide, tretinoin and daunorubicin
* denotes change
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April 2022
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April 2022
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April 2022
vincristine (cont'd) injectable Sarcoma treatment of sarcomas with vincristine, doxorubicin and cyclophosphamide SAVAC I
vinorelbine injectable Breast palliative therapy for metastatic breast cancer BRAVNAV I
combination with 3-weekly trastuzumab as palliative therapy for metastatic
vinorelbine injectable Breast BRAVTRVIN I
breast cancer
treatment of platinum resistant epithelial ovarian cancer with bevacizumab
vinorelbine injectable Gynecology GOOVBEVV I
and vinorelbine
palliative chemotherapy for re-treatment of ovarian, tubal, and peritoneal
vinorelbine injectable Gynecology GOOVVIN I
cancer
combination with cisplatin as treatment of advanced salivary gland
vinorelbine injectable Head and Neck HNSAVNP I
cancers with cisplatin and vinorelbine
adjuvant cisplatin and vinorelbine following resection of stage I, II and IIIA
vinorelbine (cont'd) injectable Lung LUAJNP I
non-small cell lung cancer
combination with cisplatin as treatment for advanced non-small cell lung
vinorelbine (cont'd) injectable Lung LUAVNP I
cancer
vinorelbine (cont'd) injectable Lung advanced non-small cell lung cancer in elderly patients LUAVVIN I
vinorelbine (cont'd) injectable Lung malignant mesothelioma LUMMVIN I
Treatment of Relapsed or Refractory Hodgkin Lymphoma with
vinorelbine (cont'd) injectable Lymphoma LYGVLD I
Gemcitabine, Vinorelbine and Doxorubicin Pegylated Liposomal
pediatric patients treated on the COG protocol AHOD0521 for
vinorelbine (cont'd) injectable Pediatric I
refractory/recurrent Hodgkin’s disease
* denotes change
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BC Cancer Benefit Drug List
April 2022
* denotes change