molecular aggregation.

Unquestionably, mechanochromic molecules with AIE effect

are valuable candidates for high-performance mechanical force-responsive luminous

materials, and mechanochromic fluorescence AIE luminogens have been reported by

Park.[33] Nevertheless, high-contrast mechanochromic fluorescence compounds

exhibiting AIE are still rare.[34] The π-conjugated fluorescent molecules with

push-pull effects involving donor-acceptor (D-A) or donor-π-acceptor (D-π-A)

structures usually possess twisted molecular conformations, which enable

f
oo
fluorescence changes in the sensitivity to mechanical force.[35,36] Furthermore,

r
-p
distorted molecular conformations are conducive to the formation of AIE effects.
re
Consequently, D-A or D-π-A type fluorophores promote high-contrast
lP

mechanochromic fluorescence.[37-40]

Fluorescent molecules with AIE characteristics are suitable not only for the
na

preparation of stimuli-responsive materials, but also for bioimaging and biosensing in

ur

vivo on account of the fact that AIE luminogens can emit bright fluorescence in vivo.
Jo

Iodide (I−) plays an important role in human physiological activities, such as

intellectual development, thyroid gland functions and basic metabolism.[41,42]

Humans intake a certain amount of I− daily. A variety of diseases, including thyroiditis,

thyrotoxicosis, hypothyroidism, hyperthyroidism, and thyroid cancer, are attributed to

the insufficient or excessive intake of I−.[43-45] Hence, there is a need to develop an

efficient and convenient method to monitor I− concentrations in human bodies for

health assessment. To date, a variety of materials have been reported for detecting and

tracking I−.[46-50] Although much progress has been achieved, the working scope of