A neurological disorder is any disorder of the nervous system that can result from structural, biochemical, or electrical abnormalities in the brain or nervous system. Examples of symptoms include paralysis, weakness, poor coordination, sensory loss, seizures, confusion, pain, and altered consciousness. There are many recognized neurological disorders, some common and some rare, which are assessed and treated by neurologists and clinical neuropsychologists.
A neurological disorder is any disorder of the nervous system that can result from structural, biochemical, or electrical abnormalities in the brain or nervous system. Examples of symptoms include paralysis, weakness, poor coordination, sensory loss, seizures, confusion, pain, and altered consciousness. There are many recognized neurological disorders, some common and some rare, which are assessed and treated by neurologists and clinical neuropsychologists.
A neurological disorder is any disorder of the nervous system that can result from structural, biochemical, or electrical abnormalities in the brain or nervous system. Examples of symptoms include paralysis, weakness, poor coordination, sensory loss, seizures, confusion, pain, and altered consciousness. There are many recognized neurological disorders, some common and some rare, which are assessed and treated by neurologists and clinical neuropsychologists.
neurological disorder is any disorder of the nervous system. Structural, biochemical or electrical
abnormalities in the brain, spinal cord or other nerves can result in a range of symptoms. Examples of symptoms include paralysis, muscle weakness, poor coordination, loss of sensation, seizures, confusion, pain and altered levels of consciousness. There are many recognized neurological disorders, some relatively common, but many rare. They may be assessed by neurological examination, and studied and treated within the specialities of neurology and clinical neuropsychology. Interventions for neurological disorders include preventive measures, lifestyle changes, physiotherapy or other therapy, neurorehabilitation, pain management, medication, operations performed by neurosurgeons or a specific diet.[1][2] The World Health Organization estimated in 2006 that neurological disorders and their sequelae (direct consequences) affect as many as one billion people worldwide, and identified health inequalities and social stigma/discrimination as major factors contributing to the associated disability and their impact.[3] Gradient coils are used to spatially encode the positions of protons by varying the magnetic field linearly across the imaging volume. The Larmor frequency will then vary as a function of position in the x, y and z-axes. Gradient coils are usually resistive electromagnets powered by sophisticated amplifiers which permit rapid and precise adjustments to their field strength and direction. Typical gradient systems are capable of producing gradients from 20 to 100 mT/m (i.e., in a 1.5 T magnet, when a maximal z-axis gradient is applied, the field strength may be 1.45 T at one end of a 1 m long bore and 1.55 T at the other[50]). It is the magnetic gradients that determine the plane of imaging—because the orthogonal gradients can be combined freely, any plane can be selected for imaging. Scan speed is dependent on performance of the gradient system. Stronger gradients allow for faster imaging, or for higher resolution; similarly, gradient systems capable of faster switching can also permit faster scanning. However, gradient performance is limited by safety concerns over nerve stimulation. Some important characteristics of gradient amplifiers and gradient coils are slew rate and gradient strength. As mentioned earlier, a gradient coil will create an additional, linearly varying magnetic field that adds or subtracts from the main magnetic field. This additional magnetic field will have components in all 3 directions, viz. x, y and z; however, only the component along the magnetic field (usually called the z-axis, hence denoted Gz) is useful for imaging. Along any given axis, the gradient will add to the magnetic field on one side of the zero position and subtract from it on the other side. Since the additional field is a gradient, it has units of gauss per centimeter or millitesla per meter (mT/m). High performance gradient coils used in MRI are typically capable of producing a gradient magnetic field of approximate 30 mT/m or higher for a 1.5 T MRI. The slew rate of a gradient system is a measure of how quickly the gradients can be ramped on or off. Typical higher performance gradients have a slew rate of up to 100–200 T·m−1·s−1. The slew rate depends both on the gradient coil (it takes more time to ramp up or down a large coil than a small coil) and on the performance of the gradient amplifier (it takes a lot of voltage to overcome the inductance of the coil) and has significant influence on image quality.
Radio frequency system[edit]
The radio frequency (RF) transmission system consists of an RF synthesizer, power amplifier and transmitting coil. That coil is usually built into the body of the scanner. The power of the transmitter is variable, but high-end whole-body scanners may have a peak output power of up to 35 kW,[51] and be capable of sustaining average power of 1 kW. Although these electromagnetic fields are in the RF range of tens of megahertz (often in the shortwave radio portion of the electromagnetic spectrum) at powers usually exceeding the highest powers used by amateur radio, there is very little RF interference produced by the MRI machine. The reason for this, is that the MRI is not a radio transmitter. The RF frequency electromagnetic field produced in the "transmitting coil" is a magnetic near-field with very little associated changing electric field component (such as all conventional radio wave transmissions have). Thus, the high-powered electromagnetic field produced in the MRI transmitter coil does not produce much electromagnetic radiation at its RF frequency, and the power is confined to the coil space and not radiated as "radio waves." Thus, the transmitting coil is a good EM field transmitter at radio frequency, but a poor EM radiation transmitter at radio frequency. The receiver consists of the coil, pre-amplifier and signal processing system. The RF electromagnetic radiation produced by nuclear relaxation inside the subject is true EM radiation (radio waves), and these leave the subject as RF radiation, but they are of such low power as to also not cause appreciable RF interference that can be picked up by nearby radio tuners (in addition, MRI scanners are generally situated in metal mesh lined rooms which act as Faraday cages.) While it is possible to scan using the integrated coil for RF transmission and MR signal reception, if a small region is being imaged, then better image quality (i.e., higher signal-to-noise ratio) is obtained by using a close-fitting smaller coil. A variety of coils are available which fit closely around parts of the body such as the head, knee, wrist, breast, or internally, e.g., the rectum. A recent development in MRI technology has been the development of sophisticated multi-element phased array[52] coils which are capable of acquiring multiple channels of data in parallel. This 'parallel imaging' technique uses unique acquisition schemes that allow for accelerated imaging, by replacing some of the spatial coding originating from the magnetic gradients with the spatial sensitivity of the different coil elements. However, the increased acceleration also reduces the signal-to-noise ratio and can create residual artifacts in the image reconstruction. Two frequently used parallel acquisition and reconstruction schemes are known as SENSE[53] and GRAPPA.[54] A detailed review of parallel imaging techniques can be found here:[55] An electromagnetic field (also EM field or EMF) is a classical (i.e. non-quantum) field produced by accelerating electric charges.[1] It is the field described by classical electrodynamics and is the classical counterpart to the quantized electromagnetic field tensor in quantum electrodynamics. The electromagnetic field propagates at the speed of light (in fact, this field can be identified as light) and interacts with charges and currents. Its quantum counterpart is one of the four fundamental forces of nature (the others are gravitation, weak interaction and strong interaction.) The field can be viewed as the combination of an electric field and a magnetic field. The electric field is produced by stationary charges, and the magnetic field by moving charges (currents); these two are often described as the sources of the field. The way in which charges and currents interact with the electromagnetic field is described by Maxwell's equations and the Lorentz force law.[2] The force created by the electric field is much stronger than the force created by the magnetic field.[3] From a classical perspective in the history of electromagnetism, the electromagnetic field can be regarded as a smooth, continuous field, propagated in a wavelike manner. By contrast, from the perspective of quantum field theory, this field is seen as quantized; meaning that the free quantum field (i.e. non-interacting field) can be expressed as the Fourier sum of creation and annihilation operators in energy-momentum space while the effects of the interacting quantum field may be analyzed in perturbation theory via the S-matrix with the aid of a whole host of mathematical techniques such as the Dyson series, Wick's theorem, correlation functions, time-evolution operators, Feynman diagrams etc. Note that the quantized field is still spatially continuous; its energy states however are discrete (the field's energy states must not be confused with its energy values, which are continuous; the quantum field's creation operators create multiple discrete states of energy called photons.)