Cardiolipin is an important phospholipid found predominantly in the inner mitochondrial membrane, where it makes up 20% of total lipids. It plays a key role in mitochondrial energy metabolism by interacting with enzymes involved in oxidative phosphorylation. Cardiolipin has a unique dimeric structure with four acyl chains that allows it to form a stable hydrogen bond network and trap protons, helping drive oxidative phosphorylation. Its structure also enables it to be targeted by fluorescent dyes like nonyl acridine orange used to label mitochondria.
Cardiolipin is an important phospholipid found predominantly in the inner mitochondrial membrane, where it makes up 20% of total lipids. It plays a key role in mitochondrial energy metabolism by interacting with enzymes involved in oxidative phosphorylation. Cardiolipin has a unique dimeric structure with four acyl chains that allows it to form a stable hydrogen bond network and trap protons, helping drive oxidative phosphorylation. Its structure also enables it to be targeted by fluorescent dyes like nonyl acridine orange used to label mitochondria.
Cardiolipin is an important phospholipid found predominantly in the inner mitochondrial membrane, where it makes up 20% of total lipids. It plays a key role in mitochondrial energy metabolism by interacting with enzymes involved in oxidative phosphorylation. Cardiolipin has a unique dimeric structure with four acyl chains that allows it to form a stable hydrogen bond network and trap protons, helping drive oxidative phosphorylation. Its structure also enables it to be targeted by fluorescent dyes like nonyl acridine orange used to label mitochondria.