RENE INDUSTRIES LIMITED

GENERAL TEST PROCEDURE

TITLE: PREPARATION AND STANDARDIZATION OF 0.1 M /0.1N SODIUM HYDROXIDE

SOLUTION
GTP NUMBER SUPERSDES Effective Date Review Date Page No.
GTP002-00 Nil. 11/2011 10/2013 Page 1 of 2

1.0 PURPOSE
1.1 To lay down the procedure for Preparation and Standardization of 0.1M/0.1N Sodium
Hydroxide Solution.

2.0 APPARATUS
2.1 Burette
2.2 Iodine flask
2.3 1000 ml volumetric flask
2.4 1000 ml beaker

3.0 REAGENTS

3.1 Sodium hydroxide AR grade

3.2 Potassium Hydrogen phthalate AR grade

3.3 Phenolphthalein

4.0 PROCEDURE
4.1 Preparation:
4.1.1 Dissolve 4.2 grams of sodium hydroxide in sufficient carbon dioxide free water to
produce1000 ml.
4.2 Standardization:
4.2.1 Weigh accurately about 0.5 grams of Potassium Hydrogen phthalate, previously powdered and
dried at 120°C for 2 hours and dissolve in 75 ml of carbon dioxide free water.
4.2.2 Add 0.1ml of phenolphthalein solution and titrate with 0.1N sodium hydroxide solutions until a
permanent pink colour is produced.
4.2.3 Each ml 0.1N sodium hydroxide = 0.02042 g of Potassium Hydrogen phthalate.

PREPARED BY CHECKED BY APPROVED BY AUTHORISED BY

NAME SWARNA OKOT FRANCIS ANJI REDDY. G MWIGO. J.B
DESIGNATION Q.C- CHEMIST Q.C- MANAGER Q.A- MANAGER PHARMACIST-IN-CHARGE.
SIGNATURE
DATE
QAP006/F06-00
 RENE INDUSTRIES LIMITED

GENERAL TEST PROCEDURE

TITLE: PREPARATION AND STANDARDIZATION OF 0.1 M /0.1N SODIUM HYDROXIDE

SOLUTION
GTP NUMBER SUPERSDES Effective Date Review Date Page No.
GTP002-00 Nil. 11/2011 10/2013 Page 2 of 2

4.2.4 Calculation

Sample weight x 0.1

= --------------------------------
Titer volume x 0.02042

# Store in bottles with well - fitted suitable stoppers which prevents access to Carbon dioxide.
# Use within 30 days from the date of preparation.

5.0 REFERENCES

5.1 I.P 1996 Page No –A213

END OF DOCUMENT

PREPARED BY CHECKED BY APPROVED BY AUTHORISED BY

NAME SWARNA OKOT FRANCIS ANJI REDDY. G MWIGO. J.B
DESIGNATION Q.C- CHEMIST Q.C- MANAGER Q.A- MANAGER PHARMACIST-IN-CHARGE.
SIGNATURE
DATE
QAP006/F06-00