MALARIA

Thick blood smear – detects presence of parasites – erythrocytes are piled in layers os that both the
erythrocyte count and Plasmodium concentration are approx. 10-20 times those observed normally in the
visual field

Plasmodium vivax : immature trophozoite P. vivax : mature trophozoite

P. malariae : mature schizont P. vivax : red cell schizont

Macrogametocytes of different types of Plasmodium

Microgametocyte and macrogametocyte of P. Falciparum

BABESIOS

LEISHMANIA

Macrophages with amastigotes

CHAGAS disease

PAROVOVIRUS B19 (FIFTH DISEASE)

WUCHERERIA BANCROFTI
-Blood smear obtained at night – Giemsa or hematoxylin and eosin – detection of microfilariae
EHRLICHIA CHAFFEENIS
PLAGUE

rod shaped bacteria are sporeless and have no flagella

ANAPLASMA PHAGOCYTOPHILUM

neutrophile granulocytes with intracellular inclusions w/ bacteria (morulae)

ANTHRAX

TULAREMIA (Rabbit Fever)

PASTURELLA MULTOCIDA
DENGUE

EPSTEIN BARR

CYTOMEGALOVIRUS

“owl eye” appearance

GAS GANGRENE – CLOSTRIDIUM PERFRINGENS
STAPHYLOCOCCUS AUREUS

Phagocytosis of MRSA

PSEUDOMONAS AERUGINOSA

HERPES SIMPLES VIRUS

Tzanck cell – positive Tzanck test

HUMAN PAPILLOMA VIRUS

Pap smear showing low-grade dysplasia – irregular clump of koilocytes (see arrow)
KAPOSI SARCOMA

POXVIRUS

oval shaped virions w/a dumb-bell core

MEASLES VIRUS

DIFFERENTIAL DIAGNOSIS OF RASHES

LEPROSY

TINEA VERSICOLOR (PITYRIASIS VERSICOLOR)

DERMATOPHYTE – TRICHOPHYTON

wet mount w/ KOH solution – fungal hyphae

CANDIDA ALBICANS

Oval budding yeast and hyphae & long pseudohyphae at 20o Germ tubes at 37o

Grocott’s methenamine silver staining of lung tissue w/ Candida albicans (black)

SPOROTRICHOSIS (ROSE GARDENER DISEASE)

COCCIDIOMYCOSIS (VALLEY FEVER)

HISTOPLASMOSIS

BLASTOMYCOSIS

PARACOCCIDIOIDOMYCOSIS
TRICHINELLOSIS

SCABIES

scabies mite