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Algae as Industrial Organisms


Photosynthetic bio-manufacturing
Stephen Mayfield PhD
California Center for Algae Biotechnology
UC San Diego

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What is bio-manufacturing?
Is the use of living systems and organisms to develop or make
useful products

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Agriculture is also bio-manufacturing

Algae is Agriculture

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Photosynthetic Bio-manufacturing: Using
Carbon Dioxide and Sunlight to Create Products
Sun ! Plants ! Products Occurs in the Chloroplast

Light Reactions produce Energy and Reducing Agents Dark Reactions produces glucose

Glyceraldehyde-3-
phosphate 4
How important is Photosynthetic Bio-Manufacturing?

All Food and 85% of our Fuel* are products of Photosynthesis!

*Petroleum (algae) and Coal (plants) are simply fossil Photosynthate


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Algae are a new platform for photosynthetic
bio-manufacturing

Inputs Conversion Outputs


Engine 6
Algae bio-manufacturing can produce a 

wide spectrum of products

Low Cost
lipids High Volume

carbs

proteins

High Cost
Low Volume
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Microalgae Production – $12 billion market
Annual Application &
Microalgae Producer Country Price (U.S. $)
Production Product
Human Nutrition $53 kg-1
3000 tonnes dry USA, China, India,
Spirulina weight Myanmar, Japan
Cosmetics
Phycobiliproteins $16 mg-1
2000 tonnes dry Human Nutrition
Chlorella Taiwan, Germany, Japan $53 kg-1
weight Cosmetics
Human Nutrition
1200 tonnes dry Australia, Israel, USA,
Dunaliella salina Cosmetics $318-$3,186 kg-1
weight Japan
B-carotene
Aphanizomenon flos- 500 tonnes dry
USA Human Nutrition $53 kg-1
aquae weight

Haematocococcus 300 tonnes dry Aquaculture $2000 -


USA, India, Israel
pluvialis weight Astaxanthin $10,596 kg-1

Crypthecodinium 240 tonnes DHA oil USA DHA oil $64 gm-1
cohnii
Shizochytrium 10 tonnes DHA oil USA DHA oil $64 gm-1
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Adapted from: Brennan, L. and Owende, P. (2010) Renewable and Sustainable Energy Reviews. 14: 557-577.

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