Common Emergency Drugs & Dose Calculations: Ayusewa

7/21/22, 3:27 PM Common Emergency Drugs & Dose Calculations - AYUSEWA
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Common Emergency Drugs & Dose
Calculations
March 9, 2021
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DOPAMINE
About Drug
https://ayusewa.com/common-emergency-drugs-dose-calculations/ 1/26
Dopamine is a prescription medicine used to treat the symptoms of low blood pressure, low cardiac
output and improves blood flow to the kidneys. Dopamine may be used alone or with other
medications.
Dopamine belongs to a class of drugs called Inotropic Agents.
Drug Usage
1 ampoule= 200mg/5ml
Amount of drug needed per 50ml infusion solution :
Amount of drug to dilute = Body weight * 3
Example: 70 kg * 3 = 210 mg
Amount of drug = (210 mg * 5 ml)/200 mg = 5.25 ml
Preparation: 44.75 ml NSS + 5.25 ml drug = 50 ml 1 ml = (210 mg * 1000) / 50 ml = 4200 mcg
Rate of Infusion: (mcg * body weight * 60 min ) / drug concentration
Example: (5 mcg * 70 * 60 ) / 4200 mcg = 5 ml / hr
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DORMICUM (MIDAZOLAM)
About Drug
Midazolam injection is used before medical procedures and surgery to cause drowsiness, relieve
anxiety, and prevent any memory of the event. It is also sometimes given as part of the anesthesia
during surgery to produce a loss of consciousness. It is also used to cause a state of decreased
consciousness in seriously ill people in intensive care units (ICU) who are breathing with the help of
a machine. It is in a class of medications called benzodiazepines. It works by slowing activity in the
← brain to allow relaxation and decreased consciousness.
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 Drug Usage
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1 ampoule= 15mg/3ml
Preparation: 45 mg ampoule (9 ml) + 36 ml NSS
Drug Concentration : 45 mg / 45 ml = 1 mg / 1 ml
Rate of Infusion:
(Desired Dose * Quantity ) / Drug Concentration
Example: (2 mg * 45 ml ) / 45 mg = 2 ml / hr
FENTANYL
About Drug
←
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Whatsa Fentanyl is used to treat breakthrough pain (sudden episodes of pain that occur despite round the
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clock treatment with pain medication) in cancer patients at least 18 years of age (or at least 16 years
 of age if using Actiq brand lozenges) who are taking regularly scheduled doses of another narcotic
Call (opiate) pain medication, and who are tolerant (used to the effects of the medication) to narcotic
Now
pain medications. It is in a class of medications called narcotic (opiate) analgesics. It works by
changing the way the brain and nervous system respond to pain.
Drug Usage
Infusion: 1 ampoule= 500 mcg/10 ml

Preparation: 10 ml Fentanyl + 40 ml NSS
Drug Concentration : 50 ml = 500 mcg
1 ml = 10 mcg
Rate of Infusion:
(Desired Dose * Quantity ) / Drug Concentration
Example: (25 mcg * 50 ml ) = 2.5 ml 500 mcg
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DOBUTAMINE
Now
About Drug
Dobutamine is indicated for patients who require positive inotropic support in the treatment of
cardiac decompensation due to depressed contractility resulting either from organic heart disease
or from cardiac surgical procedures, especially when a low cardiac output is associated with raised
pulmonary capillary pressure.
Drug Usage
1 ampoule= 250mg/5ml
Amount of drug needed per 50ml solution :
Amount of drug to dilute = Body weight * 3
Example: 70 kg * 3 = 210 mg
Amount of drug = (210 mg * 5 ml)/250 mg = 4.2 ml
Preparation: 45.8 ml NSS + 4.2 ml drug = 50 ml
Rate of Infusion:
(mcg * body weight * 60 min ) / drug concentration
Example: (4 mcg * 70 * 60 ) / 4200 mcg = 4 ml / hr
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ATRACURIUM
About Drug
Atracurium Besylate Injection is a skeletal muscle relaxant used in addition to general anesthesia, to
facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or
mechanical ventilation. Atracurium besylate injection is available in generic form.
Drug Usage
1 ampoule= 25 mg (2.5 ml)

Preparation: 4 ampoule (100 mg) + 40 ml NSS
Drug Concentration: 100 mg / 50 ml
Rate of Infusion: (Desired Dose * 50 ml) / Drug Concentration
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AMIODARONE
About Drug
Amiodarone is used to treat certain types of serious (possibly fatal) irregular heartbeat (such as
persistent ventricular fibrillation/tachycardia). It is used to restore normal heart rhythm and maintain
a regular, steady heartbeat.
Amiodarone is known as an anti-arrhythmic drug. It works by blocking certain electrical signals in the
heart that can cause an irregular heartbeat.
Drug Usage
← 1 ampoule= 150 mg (3 ml)

Loading Dose: 1 ampoule (150 mg / 3 ml) + 12 mlD5W
 A.MAINTANENCE DOSE: 360 mg in 6 hours
Whatsa ( 360 mg * 3 ml ) 150 mg = 7.2 ml
pp
7.2 ml ( amiodarone ) + 42.8 ml D5%W = 50 ml = 8.3 ml/hr
 B. 540 mg in 18 hours
Call
Now ( 540 mg * 3 ml ) / 150 mg = 10.8 ml
10.8 ml ( amiodarone ) + 39.2 ml D5%W = 2.7 ml / hr
ADRENALINE
About Drug
Adrenaline, also known as Epinephrine, is a medication and hormone. As a medication, it is used to

treat a number of conditions, including anaphylaxis, cardiac arrest, asthma, and superficial bleeding.
Inhaled epinephrine may be used to improve the symptoms of croup. It may also be used for asthma
← when other treatments are not effective. It is given intravenously, by injection into a muscle, by
 inhalation, or by injection just under the skin.
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Now Drug Usage
1 ampoule= 1 ml / 1mg
Preparation: 12 ml of Adrenaline + 38 ml D5W = 50 ml
Drug Concentration = 12 mg / 50 ml = 0.24 mg
0.24 mg * 1000 = 240 mcg / ml
Rate of Infusion: ( Desired Dose * 60 ) / 240 mcg = ml / hr
Example (2mcg * 60 min) / 240 mcg = 0.5 ml / hr
HEPARIN
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 About Drug
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 Heparin is used to prevent blood clots from forming in people who have certain medical conditions
Call or who are undergoing certain medical procedures that increase the chance that clots will form.
Now Heparin is also used to stop the growth of clots that have already formed in the blood vessels, but it
cannot be used to decrease the size of clots that have already formed
Drug Usage
1 ampoule= 25,000 IU / 5 ml
Preparation: 45 ml NSS + 25,000 ( 5 ml ) Heparin
Rate of Infusion: ( Desired Dose * Quantity ) / Drug Concentration
Example 100 units * 50 / 25,000 units = 0.2 ml / hr
HYDRALAZINE
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Hydralazine is used to treat high blood pressure. Hydralazine is in a class of medications called
vasodilators. It works by relaxing the blood vessels so that blood can flow more easily through the
body
Drug Usage
1 ampoule= 20 mg
Preparation: 20 mg dilute in 1 ml water of inj
Loading Dose: 10-20 mg over 3-5 minutes, further dilute with 10 ml NS over 3-5 mins, then repeat
after 20-30 minutes
Infusion: Reconstitute 3 ampoules ( 60 mg ) Hydralazine with 1 ml water of injection each.
Make upto 60 ml with NSS
Drug Concentration: 1 ml : 1mg
Note: Give rate between 2 and 15 mg / hr depending on BP and Pulse
INSULIN
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About Drug
Human insulin is used to control blood sugar in people who have type 1 diabetes (condition in which
the body does not make insulin and therefore cannot control the amount of sugar in the blood) or in
people who have type 2 diabetes (condition in which the blood sugar is too high because the body
does not produce or use insulin normally) that cannot be controlled with oral medications alone
Drug Usage
Preparation: 49.5 ml NSS + 50 units (0.5 ml R.I)

Rate of Infusion: (Desired Dose * Quantity) / 50 units
Example: (3 Units * 50 ml ) / 50 units = 3 ml / hr
p ( )
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LABETALOL
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About Drug
Labetalol belongs to a group of medicines called beta blockers. It’s used to treat high blood
pressure, including high blood pressure in pregnancy. It can also be used to prevent chest pain
caused by angina
Drug Usage
1 ampule ( 20 ml ) = 100 mg
Preparation: 20 ml Labetalol + 30 ml NSS
Preparation: 20 ml Labetalol 30 ml NSS
Drug Concentration: 1 ml = 2 mg
Rate of Infusion: (Desired Dose * Quantity) / Drug Concentration
Example: (5 mg * 50 ) / 100 mg = 2.5 ml / hr
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LASIX
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About Drug
Lasix is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure,
liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and
swelling in your arms, legs, and abdomen. This drug is also used to treat high blood pressure
Drug Usage
1 ampule = 20 mg ( 2ml )
Drug Concentration: 10 ampule = 200 mg (20 ml)
Preparation: 20 ml Lasix + 20 ml NSS
40 ml = 200 mg
1 ml = 5 mg
Rate of Infusion: (Desired Dose * Quantity) / Drug Concentration
Example: (10 mg/hr * 40 ml ) / 200 mg = 2 ml / hr
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LEVOPHED
About Drug
Levophed (norepinephrine bitartrate) is a vasoconstrictor, similar to adrenaline, used to treat life-

threatening low blood pressure (hypotension) that can occur with certain medical conditions or
surgical procedures. Levophed is often used during or after CPR (cardio-pulmonary resuscitation)
Drug Usage
1 ampule = 3 mg / 3 ml
Drug Concentration: 3 mg / 50 ml = 0.06 mg /1 ml
0.06 mg * 1000 mcg = 60 mcg / ml

Preparation: 3 mg + 47 ml D5W = 50 ml
Rate of Infusion: (Desired Dose * 60 min) / 60 mcg
Example: ( 2 mcg * 60 min ) / 60 mcg = 2 ml / hr
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NITROGLYCERINE
About Drug
Nitroglycerin sublingual tablets are used to treat episodes of angina (chest pain) in people who have
coronary artery disease (narrowing of the blood vessels that supply blood to the heart). It is also
used just before activities that may cause episodes of angina in order to prevent the angina from
occurring
Drug Usage
1 ampule = 50 mg ( 10 ml )
Drug Concentration: 50 mg / 50 ml = 1 mg /1 ml
1 mg * 1000 mcg = 1000 mcg / ml
Preparation: 40 ml NSS + 10 ml NTG
Rate of Infusion: (Desired Dose * 60 min) / Drug Concentration
Example: ( 5 mcg * 60 min ) / 1000 mcg = 0.3 ml / hr
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OMEPRAZOLE
About Drug
Omeprazole reduces the amount of acid your stomach makes. It’s a widely used treatment for
indigestion and heartburn and acid reflux. It’s also taken to prevent and treat stomach ulcers.
Sometimes omeprazole is taken for a rare illness caused by a tumour in the pancreas or gut called
Zollinger-Ellison syndrome.
Drug Usage
1 vial = 40 mg
← Preparation: 5 vial (200 mg) Omeprazole + 50 ml NS
 50 ml = 200 mg
Whatsa 1 ml = 4 mg
pp Rate of Infusion: (Desired Dose * Quantity) / Drug Concentration
 Example: ( 8 mg * 50 ml ) / 200 mcg = 2 ml / hr
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PHENYLEPHRINE
About Drug
Phenylephrine is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also
used to relieve sinus congestion and pressure. Phenylephrine will relieve symptoms but will not treat
the cause of the symptoms or speed recovery. Phenylephrine is in a class of medications called
nasal decongestants. It works by reducing swelling of the blood vessels in the nasal passages
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Whatsa Drug Usage
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Call 1 ampoule: 10 mg / 1 ml
Now
Preparation: 10 mg in 250 ml NS
1 ml = 40 mcg/min
Rate of Infusion: (Desired Dose * 60) / 40 mcg/ml
Example: ( 1 mcg/min * 60 ) / 40 mcg/ml = 40 mcg / min
PHENYTOIN
About Drug
Phenytoin is used to control certain type of seizures, and to treat and prevent seizures that may
← begin during or after surgery to the brain or nervous system. Phenytoin is in a class of medications
 called anticonvulsants. It works by decreasing abnormal electrical activity in the brain
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Now Drug Usage
1 ampoule: 250 mg / 5 ml
Loading Dose: 15 mg/kg at a rate not greater than 50 mg/min for 20-30 mins.
Maintenance Dose: Followed by 100 mg every 6-8 hours
Prophylaxis: 200-600 mg/day PO/IV
Antiarrythmic: 10 mg IV every 15 minutes until arrhythmia stops
PROPOFOL
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About Drug

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Propofol is an intravenous (IV) sedative-hypnotic agent that can be used for initiation and

maintenance of Monitored Anesthesia Care (MAC) sedation, combined sedation and regional
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Now anesthesia, induction of general anesthesia, maintenance of general anesthesia, and intensive care
unit (ICU) sedation of intubated, mechanically ventilated patients
Drug Usage
Infusion: 1 ampoule: 200 mg = 20 ml

Preparation: 500 mg = 50 ml without dilution
Drug Concentration: 1 ml = 10 mg
Rate of Infusion: ( Desired Dose * Quantity ) / Drug Concentration
SANDOSTATIN
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Sandostatin LAR Depot (octreotide acetate) is an octapeptide used to treat acromegaly. Sandostatin
LAR Depot is also used to reduce flushing episodes and watery diarrhea caused by cancerous
tumors (carcinoid syndrome) or tumors called vasoactive intestinal peptide tumors (VIP adenomas)
Drug Usage
1 ampoule: 100 mcg / ml

3 ampoules (300 mcg / 3 ml) + 27 ml NSS = 30 ml
Drug Concentration: 30 ml = 300 mcg
1ml = 10 mcg
Note: 25 mcg bolus followed by 25-50 mcg / hr
VASOPRESSIN
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About Drug
Vasopressin is used to manage anti-diuretic hormone deficiency. It has off-label uses and is used in
the treatment of gastrointestinal bleeding, ventricular tachycardia and ventricular defibrillation.
Vasopressin is used to treat diabetes insipidus related to low levels of antidiuretic hormone
Drug Usage
1 ampoule: 20 units / 1ml

Usual Dose: 0.01 to 0.03 units/minutes
Preparation: 20 units in 50 ml NSS
Drug Concentration: 20 units / 50 ml = 0 4 units / ml
Drug Concentration: 20 units / 50 ml = 0.4 units / ml
Rate of Infusion: ( Desired Dose * 60 ) / Drug Concentration
Example: (0.01 units/min * 60 ) / 0.4 units / ml = 1.5 ml/hr
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7/21/22, 3:27 PM Common Emergency Drugs & Dose Calculations - AYUSEWA

ICU Ambulance Services in Patna

Infusion: 1 ampoule= 500 mcg/10 ml

1 ampoule= 25 mg (2.5 ml)

← 1 ampoule= 150 mg (3 ml)

Adrenaline, also known as Epinephrine, is a medication and hormone. As a medication, it is used to

Preparation: 49.5 ml NSS + 50 units (0.5 ml R.I)

Levophed (norepinephrine bitartrate) is a vasoconstrictor, similar to adrenaline, used to treat life-

0.06 mg * 1000 mcg = 60 mcg / ml

Infusion: 1 ampoule: 200 mg = 20 ml

1 ampoule: 100 mcg / ml

1 ampoule: 20 units / 1ml

#Air ambulance #Emergency Medicine #ICU Ambulance #train ambulance

Previous Air Ambulance Service Patna

Next How does Ambulance Service Play An Important Role Today?

Why Hiring Emergency Train Ambulance Services Important Today?

How does Ambulance Service Play An Important Role Today?

Common Emergency Drugs & Dose Calculations

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Almost 57 percent of the land is vulnerable to earthquake, 68 percent to drought, 8 percent to

ambulance services in India.

A Unit of SabSaman Private Limited

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